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Global Medical and Health Communication

gmhc
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Published by Universitas Islam Bandung

ISSN : 23019123 EISSN : 24605441 DOI : https://doi.org/10.29313/gmhc

Core Subject : Health, Science,

Dentistry Health Professions Immunology & microbiology Nursing Public Health

Global Medical and Health Communication is a journal that publishes research articles on medical and health published every 4 (four) months (April, August, and December). Articles are original research that needs to be disseminated and written in English. Subjects suitable for publication include but are not limited to the following fields of anesthesiology and intensive care, biochemistry, biomolecular, cardiovascular, child health, dentistry, dermatology and venerology, endocrinology, environmental health, epidemiology, geriatric, hematology, histology, histopathology, immunology, internal medicine, nursing sciences, midwifery, nutrition, nutrition and metabolism, obstetrics and gynecology, occupational health, oncology, ophthalmology, oral biology, orthopedics and traumatology, otorhinolaryngology, pharmacology, pharmacy, preventive medicine, public health, pulmonology, radiology, and reproductive health.

Arjuna Subject : Kedokteran - Epidemilogi

Articles 422 Documents

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Toksisitas Akut Ekstrak Air Buah Pepaya (Carica papaya L.) Muda terhadap Morfologi Eritrosit Yuktiana Kharisma; Eka Hendryanny; Astari P. Riani
Global Medical & Health Communication (GMHC) Vol 5, No 2 (2017)
Publisher : Universitas Islam Bandung

Pepaya (Carica papaya L.) adalah salah satu obat tradisional yang digunakan untuk mengatasi masalah kesehatan. Pepaya mengandung beberapa substansi fitokimia seperti saponin, alkaloid, terpenoid, dan flavonoid. Saponin dan alkaloid diketahui mampu berinteraksi dengan membran eritrosit dan menyebabkan disintegrasi membran sehingga dapat menyebabkan kerusakan pada eritrosit. Penelitian ini bertujuan mengetahui toksisitas akut ekstrak air buah pepaya muda terhadap morfologi eritrosit melalui pengamatan sediaan apus darah tepi. Metode penelitian ini adalah eksperimental laboratorium dilakukan di Laboratorium Biomedis, Fakultas Kedokteran, Universitas Islam Bandung periode Januari–Februari 2016. Penentuan kelompok dosis berdasar atas proposed (new) recommended method menggunakan 11 ekor tikus yang diberi dosis oral ekstrak air buah pepaya muda 50, 200, 400, 800, 1.000, 1.500, 2.000, 3.000, 4.000, 5.000 mg/kgBB masing-masing dan satu tikus hanya diberikan air sebagai kelompok kontrol. Pengamatan dilakukan setelah 24 jam pemberian ekstrak. Hasil pengamatan sediaan apus darah tepi menunjukkan tidak terdapat perubahan morfologi eritrosit baik bentuk, ukuran, dan warnanya. Simpulan, ekstrak air buah pepaya muda tidak memiliki toksisitas akut terhadap morfologi eritrositACUTE TOXICITY OF UNRIPE PAPAYA FRUIT (CARICA PAPAYA L.) WATER EXTRACT TO MORPHOLOGY OF ERYTHROCYTEPapaya (Carica papaya L.) is one of traditional medicines which was used to overcome health things. It is contained of some phytochemicals substance such as saponin, alkaloid, terpenoid, and flavonoid. Both saponin and alkaloid were known having an ability to interract with eryhtrocyte membran and cause membrane disintegrity that can destruct the erythrocyte. This study was aimed to know the acute toxicity of the aqueous extract of unripe papaya fruit to the erythrocyte morphology by observe the peripheral blood smear. The method of this study was conducted experimental laboratory at Loboratory of Biomedical, Faculty of Medicine, Universitas Islam Bandung in January–February 2016. Determination of dose group is based on proposed (new) recommended method with 11 rats were administrated oral dose 50, 200, 400, 800, 1,000, 1,500, 2,000, 3,000, 4,000, 5,000 mg/kgBW of unripe papaya fruit aqueous extract, and one rat was only given water as control group. Observation had been done at 24 hours after extract administrating. It showed that there was not any abnormal morphology, size, and chromatic changes of erythrocyte in blood smear observations. In conclusion, the aqueous extract of unripe papaya fruit do not have the acute toxicity to erythrocyte morphology.

Difference Duration of Labor at BC-MK15 Birth Chair with Conventional Bed in Multiparous Fitriani Fitriani; Johanes Cornelius Mose; Herry Herman
Global Medical & Health Communication (GMHC) Vol 6, No 2 (2018)
Publisher : Universitas Islam Bandung

Prolonged labor increases the mortality and morbidity of mother and baby. The philosophy of childbirth is a natural process by taking the upright positions. The BC-MK15 birth chairs can facilitate the vertical position of the delivery mother. This study aims to analyze the difference of childbirth duration in the BC-MK15 birth chair with the conventional bed in multiparous. This research was an experimental study of posttest-only control group design. Experimented at Pelayanan Obstetri Neonatal Emergensi Dasar/PONED (Basic Emergency Obstetric and Neonatal Care/BEONC) Puskesmas (Public Health Center) Garuda, Puter, and Ibrahim Aji Bandung from 17 April–26 May 2017. The research samples were 30 multiparous on their first stage active phase of treatment and control group. Sampling method using a random permuted block. Birth measurements using the digital Q & Q stopwatch. The results of the duration during the active phase of first stage BC-MK15 was shorter 250.44 minutes than conventional bed 271.61 minutes (p=0.038). The second stage of the BC-MK15 birth chair was shorter 20.67±2(1.02) minutes than the conventional beds of 26.06±2(1.08) minute (p=0.001). The total duration of the labor of BC-MK15 was 269.42 minutes shorter than conventional bed 299.09 minutes (p=0.011). In conclusion, the duration of childbirth is shorter in the BC-MK15 birth chair than the conventional bed in multiparous. PERBEDAAN LAMA PERSALINAN DI KURSI PERSALINAN BC-MK15 DENGAN TEMPAT TIDUR KONVENSIONAL PADA MULTIPARAPersalinan lama meningkatkan mortalitas dan morbiditas ibu dan bayi. Upaya yang dapat dilakukan sesuai filosofi persalinan adalah proses alamiah dengan memanfatkan posisi tegak. Kursi persalinan BC-MK15 dapat memfasilitasi posisi tegak pada ibu bersalin. Penelitian ini bertujuan menganalisis perbedaan lama persalinan di kursi persalinan BC-MK15 dengan tempat tidur konvensional pada multipara. Penelitian ini merupakan studi eksperimental posttest-only control group design. Sampel penelitian multipara kala I fase aktif di Puskesmas Pelayanan Obstetri Neonatal Emergensi Dasar (PONED) Garuda, Puter, dan Ibrahim Aji Kota Bandung. Penelitian dilakukan pada 17 April−26 Mei 2017 yang memenuhi kriteria inklusi berjumlah 30 sampel tiap-tiap kelompok perlakuan dan kontrol. Pengambilan sampel menggunakan random permuted block. Pengukuran lama persalinan menggunakan stopwatch digital merek Q&Q. Hasil penelitian lama persalinan kala I fase aktif kursi persalinan BC-MK15 lebih singkat 250,44 menit daripada tempat tidur konvensional 271,61 menit (p=0,038). Kala II kursi persalinan BC-MK15 lebih singkat 20,67±2(1,02) menit daripada tempat tidur konvensional 26,06±2(1,08) menit (p=0,001). Total lama persalinan kursi persalinan BC-MK15 lebih singkat 269,42 menit daripada tempat tidur konvensional 299,09 menit (p=0,011). Simpulan, lama persalinan lebih singkat pada kursi persalinan BC-MK15 daripada tempat tidur konvensional pada multipara.

Sanitasi, Higiene Perorangan, dan Pencemaran Tanah oleh Cacing pada Kecacingan pada Anak di Kelurahan Liliba, Kecamatan Oebobo Kota Kupang, Provinsi Nusa Tenggara Timur Eni Sinaga; Wanti Wanti; Kusmiyati Kusmiyati
Global Medical & Health Communication (GMHC) Vol 2, No 1 (2014)
Publisher : Universitas Islam Bandung

Penyakit kecacingan banyak ditemukan di daerah dengan kelembaban tinggi terutama pada kelompok masyarakat dengan higiene perorangan dan sanitasi lingkungan yang kurang baik. Tujuan penelitian ini untuk mengetahui hubungan kondisi sanitasi, higiene perorangan, pencemaran tanah oleh cacing dengan kejadian kecacingan pada anak usia 1–5 tahun di Kelurahan Liliba, Kecamatan Oebobo Kota Kupang, Provinsi Nusa Tenggara Timur. Penelitian observasional dengan rancangan cross sectional study dilakukan pada Mei–November 2012. Sampel penelitian 50 anak usia 1–5 tahun sebanyak 50 orang yang diambil secara random sampling. Data dianalisis menggunakan uji chi kuadrat (X2) dengan program statistical product and service solution (SPSS). Prevalensi kecacingan pada anak usia 1-5tahun di Kelurahan Liliba adalah 38%. Hasil Uji chi kuadrat menunjukkan hanya ada satu variabel yang berhubungan dengan kejadian kecacingan di Liliba yaitu higiene perorangan (p=0,005). Variabel yang tidak berhubungan dengan kejadian kecacingan pada anak 1–5 tahun di Liliba yaitu kondisi sarana air bersih (p=0,07), kondisi jamban (p=0,128), dan pencemaran tanah oleh cacing (p=0,309). Penelitian ini membuktikan ada hubungan bermakna antara higiene perorangan dan kejadian kecacingan, sehingga diharapkan orangtua lebih memperhatikan higiene perorangan anaknya seperti memotong kuku, mencuci tangan setelah bermain dan sebelum makan, mencuci tangan setelah buang air besar dan memberikan alas kaki saat bermain. Dinkes Kota dan Puskesmas khususnya secara periodic setiap 6 bulan sekali diharapkan melakukan tindakan pencegahan dan penanggulangan kecacingan dengan penyuluhan dan pemberian obat cacing kepada anak usia 1–5 tahun. SANITATION, PERSONAL HYGIENE, AND HELMINTH CONTAMINATION OF HELMINTH INFECTION IN CHILDREN AT LILIBA SUBDISTRICT, OEBOBO KUPANG, EAST NUSA TENGGARA PROVINCEHelminth infection was found especially in the area with high humidity and in the community with bad personal higiene and inadequate sanitation. The objective of this study is to describe the relation between sanitation, personal hygiene, helminth contamination in the soil and helminth infection in children 1–5 years old in Liliba subdistrict Oebobo Kupang, East Nusa Tenggara Province. This was an observational study with cross sectional approach was done on May to November 2012. A systematic random sampling of 50 children 1–5 years old involved in this study. Analysis using statistical product and servicesolution (SPSS) program ver. 17 was done with chi square (X2). The results showed that the prevalence of helminth infection on children 1–5 years old was 38%. One variable showed significant relationship with helminth infection is personal hygiene with p=0.005 while the availability of clean water, sanitation and soil contamination showed no significant relationship with p=0.07; p=0.128 and p=0.309 respectivelly. The study emphasized the need for personal hygiene that encouraged parents to help children exercise personal hygiene better. Several activities such as nail cutting, washing hands after playing and before eating, washing hands after defecating and using sandals for feet protections need to be promoted. Local Health department need to prevent the infection by promoting healthy living and distribute preventive drug especially for children 1–5 years old.

Pilihan Karier Lulusan Program Pendidikan Profesi Dokter Universitas Islam Bandung Tahun 2015 Eka Nurhayati; Titik Respati; Budiman Budiman
Global Medical & Health Communication (GMHC) Vol 4, No 2 (2016)
Publisher : Universitas Islam Bandung

Tahun 2014 merupakan tahun penting bagi dokter di Indonesia karena mulai diberlakukannya Jaminan Kesehatan Nasional (JKN) dan persiapan menjelang Masyarakat Ekonomi ASEAN (MEA) 2015. Alasan tersebut dapat memengaruhi pilihan karier lulusan fakultas kedokteran di Indonesia. Banyak penelitian terkait pemilihan karier kedokteran telah dilakukan di luar negeri, namun penelitian semacam ini belum pernah dilakukan di Fakultas Kedokteran Universitas Islam Bandung (FK Unisba). Tujuan penelitian adalah mengetahui pilihan karier lulusan Program Pendidikan Profesi Dokter (P3D) FK Unisba tahun 2015. Penelitian ini merupakan penelitian kuantitatif dengan rancangan deskriptif potong lintang, dilakukan pada bulan April 2015 menggunakan kuesioner dengan sampel 53 orang menggunakan teknik whole sampling. Hasil penelitian menunjukkan bahwa mayoritas lulusan program P3D FK Unisba 2015 adalah perempuan (68%) dan profesi yang paling banyak diminati adalah dokter spesialis (85%). Tempat bekerja yang paling banyak diminati adalah rumah sakit (74%). Lokasi pekerjaan yang paling banyak diminati ialah wilayah urban di Indonesia (68%). Pilihan sektor pekerjaan tidak menunjukkan perbedaan yang signifikan antara sektor publik (40%) dan swasta (43%). Simpulan penelitian ini menunjukkan bahwa lulusan P3D FK Unisba 2015 lebih banyak berminat pada profesi dokter spesialis dan bekerja di rumah sakit yang berlokasi di wilayah urban Indonesia. CAREER OPTIONS AMONG GRADUATES OF FACULTY OF MEDICINE BANDUNG ISLAMIC UNIVERSITY YEAR 2015Year 2014 was a very important moment for doctors in Indonesia since the Government began to enforce Jaminan Kesehatan Nasional (JKN) and the preparation for the ASEAN Economic Society (AEC) by 2015. Both reasons might influenced the choice of career of medical graduates in Indonesia. Many medical careers selection related research has been conducted abroad, but this kind of research has not been done in Medical Faculty of Bandung Islamic University (FK Unisba). The purpose of this study was to determine the career choice of graduates of Physician Professional Education Program (P3D) FK Unisba year 2015. This was cross sectional design. The study was conducted in April 2015 using questionnaire with 53 respondents. The results of this study indicated that the majority of P3D graduates FK Unisba were women (68%), with the most favourable profession were specialists (85%). The most demanding work place was hospital (74%), location of the most interesting work was the urban area in Indonesia (68%). Selection work sector showed no significant differences between the public sector (40%) and private (43%). The conclusion of this study showed that graduates of P3D FK Unisba year 2015 mostly interested to be specialist and works in hospital which located in urban area in Indonesia.

Akurasi Kriteria Voltase Elektrokardiografi Hipertrofi Ventrikel Kiri untuk Membedakan Jenis Geometri Hipertrofi Ventrikel Kiri Octo Tumbur; Zainal Safri; Refli Hassan
Global Medical & Health Communication (GMHC) Vol 5, No 2 (2017)
Publisher : Universitas Islam Bandung

Perbedaan jenis geometri hipertrofi ventrikel kiri dikaitkan dengan risiko penyakit kardiovaskular yang berbeda. Ekokardiografi dengan bantuan kriteria voltase elektrokardiografi (EKG) hipertrofi ventrikel kiri dapat membedakan jenis geometri hipertrofi ventrikel kiri. Tujuan penelitian mengetahui peranan berbagai kriteria voltase EKG hipertrofi ventrikel kiri untuk membedakan jenis geometri hipertrofi ventrikel kiri. Dilakukan penelitian potong lintang periode Juni–November 2015 terhadap 100 pasien di poliklinik dan rawat inap kardiologi RSUP H. Adam Malik Medan. Dilakukan anamnesis, pengukuran indeks massa tubuh, serta pemeriksaan EKG dan ekokardiografi. Jika hasil kriteria EKG hipertrofi ventrikel kiri Sokolow-Lyon tidak dipenuhi maka didapatkan geometri ventrikel kiri normal dengan sensitivitas 60%, spesifisitas 72,22%, dan akurasi 71%. Untuk jenis geometri eksentrik hipertrofi ventrikel kiri didapatkan bila Cornel voltase tidak dipenuhi, sensitivitasnya 25%, spesifisitas 71,88% dan akurasi 55%. Untuk jenis hipertrofi geometri konsentrik bila rasio RV6/V5 >1 dipenuhi, sensitivitasnya 55,56%, spesifisitas 56,36% dan akurasi 56%. Jika rasio RV6/V5 >1 tidak dipenuhi, jenis geometri konsentrik remodeling hipertrofi ditentukan dengan sensitivitas 55,56%, spesifisitas 49,45% dan akurasi 50%. Pada penelitian ini juga didapatkan sensitivitas dan spesifisitas kriteria Sokolow-Lyon untuk hipertrofi ventrikel kiri secara ekokardiografi dengan sensitivitas 72,22% dan spesifisitas 60,00%, kriteria Cornel voltase untuk hipertrofi ventrikel kiri secara ekokardiografi dengan sensitivitas 77,78% dan spesifisitas 70,00%, dan kriteria rasio RV6/V5 untuk hipertrofi ventrikel kiri secara ekokardiografi dengan sensitivitas 51,11% dan spesifisitas 70,00%. Secara keseluruhan, sensitivitas dan spesifisitas termasuk lemah. Simpulan, berbagai kriteria EKG ventrikel kiri dapat membedakan jenis geometri hipertrofi ventrikel kiri. Kriteria EKG hipertrofi kiri voltase, yaitu Sokolow-Lyon dan Cornel voltase sensitivitas dan spesifisitas lebih baik dibanding dengan rasio RV6/V5.ACCURACY OF CRITERIA VOLTAGE ELECTROCARDIOGRAPHY LEFT VENTRICULAR HYPERTROPHY TO DISTINGUISH TYPES OF LEFT VENTRICULAR HYPERTROPHY GEOMETRYThe different types of left ventricular hypertrophy geometry is associated with different risk of cardiovascular disease. Echocardiography is the gold standard for diagnosis of left ventricular hypertrophy. Electrocardiographic (ECG)left ventricular hypertrophy voltage criteria can distinguish the type of geometry of left ventricular hypertrophy. The purpose of this study to find out the role of various voltage ECG criteria to distinguish the type of geometry of left ventricle hypertrophy. A cross-sectional study doing from June to November 2015 on 100 patients in cardiology clinic and inpatient at Adam Malik Hospital, Medan, through anamnesis, body mass index measurement, ECG and echocardiography examinations. If the Sokolow-Lyon ECG criteria for left ventricular hypertrophy did not met, normal left ventricular geometry was diagnosed with 60% sensitivity, 72.22% specificity and 71% accuracy. The eccentric left ventricular hypertrophy geometry was diagnosed if Cornel voltage was not fulfilled, with 25% sensitivity, 71.88% specificity and 55% accuracy. The concentric hypertrophy geometry was diagnosed if the RV6/V5 ratio >1, with 55.56% sensitivity, 56.36% specificity and 56% accuracy. If the RV6/V5 ratio >1 are not met, concentric hypertrophic remodeling geometry was diagnosed with a sensitivity of 55.56%, a specificity of 49.45% and an accuracy of 50%. This study also found the sensitivity and specificity for left ventricular hypertrophy in echocardiography of Sokolow-Lyon criteria were 72.22% and 60.00%, the Cornel voltage criteria with a sensitivity of 77.78% and a specificity of 70.00%, and RV6/V5 ratio criteria with a sensitivity of 51.11% and a specificity of 70.00%. The overall sensitivity and specificity was low. In conclusion, various criteria of ECG left ventricular geometry voltage can differentiate left ventricular hypertrophy geometry types. Sokolow-Lyon and Cornell voltage criteria are more sensitive and specific than the RV6/V5 ratio.

Pengaruh Variasi Lama Penyimpanan Air Rendaman Jerami Padi terhadap Jumlah Telur Nyamuk Aedes aegypti di Ovitrap Model Kepanjen Putri Fitri Alfiantya; Aswin Djoko Baskoro; Lilik Zuhriyah
Global Medical & Health Communication (GMHC) Vol 6, No 1 (2018)
Publisher : Universitas Islam Bandung

Salah satu teknologi yang dapat digunakan untuk mengontrol perkembangbiakan vektor demam berdarah dengue (DBD) adalah ovitrap. Ovitrap adalah perangkap telur yang digunakan untuk mendeteksi keberadaan vektor demam berdarah, seperti Aedes albopictus dan Aedes aegypti. Penelitian ini bertujuan mengetahui pengaruh lama penyimpanan atraktan air rendaman jerami padi terhadap jumlah telur nyamuk Aedes aegypti pada ovitrap model Kepanjen yang dimodifikasi. Desain penelitian ini adalah pre-experimental design dengan one-group post-test only. Penelitian dilakukan pada bulan Januari–Maret 2014 di Laboratorium Parasitologi Fakultas Kedokteran Universitas Brawijaya dan Laboratorium Kimia Dasar FMIPA Universitas Brawijaya. Sebanyak 100 ekor nyamuk masing-masing diletakkan dalam 6 buah kandang. Setiap kandang diletakkan 4 buah ovitrap dengan usia penyimpanan atraktan yang berbeda, yaitu 0, 12, 34, dan 90 hari. Pengambilan telur dilakukan pada hari ke-3 dan ke-6. Hasil penelitian menunjukkan tidak ada perbedaan bermakna jumlah telur yang terperangkap antara usia penyimpanan atraktan (p=0,694). Air rendaman jerami padi sampai dengan usia 90 hari masih dapat digunakan sebagai atraktan pada ovitrap model Kepanjen. Simpulan, variasi lama penyimpanan atraktan air rendaman jerami padi tidak memberikan pengaruh pada jumlah telur Aedes aegypti yang terperangkap di ovitrap model Kepanjen. VARIANCE OF RICE STRAW INFUSED WATER STORAGE LENGTH AND ITS EFFECTS ON THE AMOUNT OF AEDES AEGYPTI MOSQUITO EGGS IN KEPANJEN MODEL OVITRAPOne of the technology that can be used in order to control the dengue vector breeding is ovitrap. Ovitrap is an egg trap which is used to detect the existence of dengue vector, such as Aedes aegypti and Aedes albopictus. This research aim to describe the effect of rice straw infused water storage length attractant to Aedes aegypti eggs amount trapped in Kepanjen model ovitrap. The study was pre-experimental with one-group post-test only conducted on January–March 2014 at Laboratory of Parasitology, Faculty of Medicine, Universitas Brawijaya and General Chemistry Laboratory, Faculty of Science, Universitas Brawijaya. In each of six cages, 100 mosquitoes were placed with 4 ovitraps with different storage length of rice straw infused water attractant, i.e. 0, 12, 34, and 90 days. Eggs collection was done at day 3rd and day 6th. The result showed that there was no significant differences on the number of eggs trapped among each different attractant storage length (p=0.694). Therefore, rice straw infused water can be use up to 90 days as an attractant in Kepanjen model ovitrap. In conclusion, the variation of rice straw infused water storage length attractant did not provide effects to the number of Aedes aegypti eggs trapped in Kepanjen model ovitrap.

Karakteristik dan Gaya Hidup Pasien Hipertensi di Rumah Sakit Al-Islam Bandung Rizky Ramdhani; Titik Respati; Siska Nia Irasanti
Global Medical & Health Communication (GMHC) Vol 1, No 2 (2013)
Publisher : Universitas Islam Bandung

Hipertensi merupakan masalah kesehatan yang semakin penting, karena prevalensi yang meningkat setiap tahun. Pada tahun 2000 World Health Organization memperkirakan prevalensi hipertensi sebesar 26,4% di dunia. Menurut Riskesdas tahun 2007 memperkirakan prevalensi hipertensi sebesar 31,7%. Faktor risiko hipertensi dapat dibedakan menjadi non modifiable (seperti keturunan, jenis kelamin, dan usia) dan modifiable (seperti kurang olahraga, obesitas, dan garam). Penelitian ini bertujuan untuk mengetahui karakteristik dan gaya hidup pasien hipertensi di RS Al-Islam Bandung. Penelitian ini adalah penelitian deskriptif analitik dengan pendekatan cross sectional. Subjek penelitian adalah pasien yang datang ke poli rawat jalan Instalasi Penyakit Dalam RS Al-Islam periode 1 April–31 Juli 2012. Sebanyak 230 subjek mengikuti penelitian terdiri atas 114 pasien hipertensi dan 116 pasien normotensi. Hasil penelitian menunjukkan pasien hipertensi rata-rata berusia 61–70 tahun (38,6%), berjenis kelamin perempuan (68,4%), berpendidikan S-1 (42,1%), ibu rumah tangga 48,2%, memiliki faktor genetik (66,7%), serta tidak rutin melakukan olahraga (47,4%). Hasil penelitian memperlihatkan faktor risiko yang mempunyai hubungan dengan hipertensi adalah usia (p=0,0001), jenis kelamin (p=0,007), riwayat hipertensi (p=0,048), tidak rutin olahraga (p=0,004), dan tidak melakukan pencegahan (p=0,0001). Simpulan penelitian ini adalah kejadian hipertensi dipengaruhi oleh usia, jenis kelamin, faktor risiko, dan kebiasaan olahraga rutin. Hasil ini diharapkan dapat dipergunakan untuk meningkatkan pengetahuan tentang faktor risiko hipertensi sehingga dapat menurunkan kejadian hipertensi di masyarakat. CHARACTERISTIC AND LIFESTYLE OF HYPERTENSION PATIENTS AT AL-ISLAM HOSPITAL BANDUNGHypertension is an increasingly important health problem, showed by an increasing prevalence every year. In 2000 the World Health Organization estimates that the prevalence of hypertension in the world were 26.4%. According to Riskesdas in 2007 it was estimated that the prevalence of hypertension in Indonesia was 31.7%. Risk factors for hypertension can be divided into non modifiable (such as heredity, gender, and age) and modifiable (such as lack of exercise, obesity and salt). This study aimed to investigate the patient's characteristics and lifestyle. This is a descriptive study using cross sectional analytic approach. Subjects were patients attending the outpatient clinic at Al-Islam Hospital, Internal Medicine Department during 1st April to 31st July 2012. A total of 230 subjects completed the study with 114 subjects diagnosed as hypertensive and 116 normotensive. The results showed that majority of hypertensive patients were 61–70 years old (38.6%), female (68.4%), university graduate (42.1%), housewives 48.2%, has genetic factor (66.7%), and doing exercise irregularly (47.4%). The results showed that risk factors associated with hypertension were age (p=0.0001), gender (p=0.007), genetic factors (p=0.048), irregular exercise (p=0.004) and no prevention of hypertension (p=0.001). The conclusion of this study is the incidence of hypertension is influenced by age, sex, genetic factors and regular exercise habits. These results are expected to be used to increase knowledge about risk factors for hypertension that may be used to help decreasing the incidence of this disease in the community.

Effectiveness of Various Mosquito Attractant Solutions to Control Mosquito Population Faridah, Lia; Albert, Christian; Fauziah, Nisa
Global Medical & Health Communication (GMHC) Vol 7, No 1 (2019)
Publisher : Universitas Islam Bandung

The vector-borne disease is a disease caused by an organism that can transmit disease between human or animal to human. In Indonesia, several vector-borne diseases are a burden of the government including dengue fever, chikungunya, filariasis, and malaria. The attractive baited lethal ovitrap (ALOT) is a novel strategy to alleviate mosquito populations in three main actions: attraction, an adulticide, and larvacide. Research using plant infusion can attract mosquitoes to lay their eggs is needed. This study aims to compare the effectiveness of the mosquito repellent solution using materials from organic waste in Bandung. This study was a quantitative analytic study with a quasi-experimental design conducted in the Faculty of Medicine Universitas Padjadjaran area in October 2016–July 2017. Research subjects are mosquito eggs in a solution which placed at 25 different places for every solution. The analysis was performed using Kruskal-Wallis test followed by the Dunn test. The result of the Kruskal-Wallis test indicates the difference of effectiveness of each solution (p<0.05). Based on the results of the Dunn test, the most significant difference found in the solution of wood shavings with the vegetable waste solution and the solution of wood shavings with corn straw (p<0.05). In conclusion, there is a difference in the effectiveness of the mosquito repellent solutions and the most attractive solution for mosquitoes to oviposit is the corn straw solution. EFEKTIVITAS BERBAGAI LARUTAN PENARIK NYAMUK UNTUK MENGONTROL POPULASI NYAMUKPenyakit tular vektor adalah penyakit yang disebabkan oleh organisme yang dapat mentransmisikan penyakit antarmanusia atau hewan ke manusia. Di Indonesia, terdapat beberapa penyakit tular vektor yang masih menjadi beban pemerintah, di antaranya demam berdarah, chikungunya, penyakit kaki gajah, dan malaria. Attractive baited lethal ovitrap (ALOT) merupakan strategi baru untuk menurunkan populasi nyamuk dalam tiga aksi utama, yaitu attraction, adulticide, dan larvacide. Penelitian terkait larutan dari tanaman yang dapat menarik nyamuk sangat diperlukan. Penelitian ini bertujuan membandingkan efektivitas larutan penarik nyamuk dengan menggunakan bahan dari limbah organik yang ada di Kota Bandung. Penelitian ini adalah penelitian analitik kuantitatif dengan desain quasi-eksperimental yang dilakukan di lingkungan Fakultas Kedokteran Universitas Padjadjaran pada bulan Oktober 2016–Juli 2017. Subjek penelitian merupakan telur nyamuk yang ada pada larutan yang diletakkan pada 25 titik untuk setiap larutan. Analisis dengan Uji Kruskal-Wallis yang dilanjutkan dengan Uji Dunn. Hasil penelitian dengan Uji Kruskal-Wallis menunjukkan perbedaan efektivitas tiap-tiap larutan (p<0,05). Berdasar atas hasil Uji Dunn, perbedaan yang paling signifikan terdapat pada larutan serutan kayu dengan larutan sampah sayur dan larutan serutan kayu dengan jerami jagung (p<0,05). Simpulan, terdapat perbedaan efektivitas larutan penarik nyamuk dan larutan yang menarik nyamuk paling banyak untuk bertelur adalah larutan jerami jagung.

Perbedaan Efek Infusa Bubuk Kedelai (Glycine max), Jamur Tiram (Pleurotus ostreatus), dan Campuran Keduanya terhadap Kadar Kolesterol LDL, Ekspresi Gen Reseptor LDL Hati, dan Berat Omentum Majus Mencit Model Hiperlipidemia Rizky Suganda Prawiradilaga; M. Nurhalim Shahib; Siti Nur Fatimah
Global Medical & Health Communication (GMHC) Vol 4, No 1 (2016)
Publisher : Universitas Islam Bandung

Angka kejadian dislipidemia di Indonesia semakin meningkat. Dislipidemia dan obesitas abdominal merupakan faktor risiko penyakit kardiovaskular. Diperlukan solusi yang efektif dengan bahan alami seperti kedelai dan jamur tiram. Tujuan penelitian ini melihat efektivitas infusa bubuk kedelai, jamur tiram, dan campuran keduanya terhadap kadar kolesterol LDL, ekspresi gen LDLR hati, dan berat omentum majus mencit percobaan. Penelitian eksperimental di Laboratorium Farmakologi RSUP Dr. Hasan Sadikin Bandung tahun 2010 memakai rancangan postes kelompok kontrol. Mencit jantan sebanyak 20 ekor dibagi 5 kelompok perlakuan, yaitu A) pakan standar, B) induksi kolesterol, C) infusa kedelai dengan induksi kolesterol, D) infusa jamur tiram dengan induksi kolesterol, dan E) infusa campuran dengan induksi kolesterol. Pada akhir penelitian mencit dikorbankan lalu dibedah untuk diambil darah jantung, juga sedikit bagian hati dan omentum majus. Kolesterol LDL darah kelompok E (12±5,48 mg/dL) sama dengan kelompok D (12±6,06 mg/dL), tetapi lebih rendah daripada kelompok C (15±5,35 mg/dL) dan kelompok B (13,5±5,45 mg/dL), namun tidak signifikan. Didapatkan ekspresi gen LDLR yang sedang pada kelompok A dan C, ekspresi gen LDLR yang lemah pada kelompok B, dan tidak terekspresi pada kelompok D dan E. Berat basah omentum majus kelompok E (0,40±0,07 g) lebih rendah bermakna dibanding kelompok A (0,55±0,07 g), B (0,8±0,49 g), C (1,28±0,28 g), D (0,74±0,11 g) (p<0,05). Berat kering omentum majus kelompok E (0,16±0,03 g) lebih rendah bermakna daripada kelompok B (0,27±0,25 g), C (0,39±0,06 g), dan D (0,31±0,07 g) (p=0,025). Simpulan, infusa kedelai 100 mg/hari meningkatkan kadar kolesterol LDL darah dan berat omentum majus, tetapi jamur tiram 75 mg/hari sebaliknya, menurunkan kadar kolesterol LDL darah dan berat omentum majus mencit. DIFFERENCES IN GIVING EFFECT OF SOYBEAN POWDER INFUSION (GLYCINE MAX), OYSTER MUSHROOM (PLEUROTUS OSTREATUS), AND MIXED OF BOTH ON LDL-C LEVELS, LDL-R GENE EXPRESSION, AND GREATER OMENTUM WEIGHT OF HYPERLIPIDEMIA MODEL MICEThe incidence of hypercholesterolemia in Indonesia are increase. Hyperlipidemia and abdominal obesity is a risk factor for cardiovascular disease. Needed an effective solution with natural substance like soy and oyster mushrooms. The purpose of this study was to see the effectiveness of the soybean powder infusion, oyster mushrooms, and a mixture of both on LDL cholesterol levels, liver LDLR gene expression, and the weight of the experimental mice greater omentum. This experimental study conducted in the Laboratory of Pharmacology Dr. Hasan Sadikin Hospital Bandung in 2010, using a posttest only. Twenty male mice were divided in five treatment groups, namely A) standard diet, B) induction of cholesterol, C) soybean infuse with cholesterol induction, D) oyster mushrooms infuse with induction of cholesterol, and E) mixed infuse with cholesterol induction. At the end of the study mice were dissected for blood drawn from the heart, taken little part of his liver, and the greater omentum were taken. The results of blood LDL cholesterol measurement group E (12±5.48 mg/dL) similar to group D (12±6.06 mg/dL) but lower than group C (15±5.35 mg/dL) and group B (13.5±5.45 mg/dL) but they were not significant. Medium LDLR gene expression was found in group A and group C, a weak LDLR gene expression in group B, and no expression LDLR gene in group D and group E. Measurement results of greater omentum wet weight group E (0.40±0.07 g) was lower than in group A (0.55±0.07 g), B (0.8±0.49 g), C (1,28±0.28 g), D (0.74±0.11 g), with significance level significant (p<0.05). Measurement results of greater omentum dry weight group E (0.16±0.03 g) was lower than in group B (0.27±0.25 g), C (0.39±0.06 g), D (0,31±0.07 g), and they were significant (p=0.025). In conclusion, soy infuse at 100 mg/day increase blood LDL cholesterol levels and increase the weight of greater omentum, whereas the opposite oyster mushrooms at 75mg/day lower blood LDL cholesterol levels and reduce the weight of greater omentum.

Nasopharyngeal Carcinoma (NPC) Related Human Leukocyte Antigen (HLA) Haplotype Sharing among Southern East Asian Population Rika Yuliwulandari; Katsushi Tokunaga
Global Medical & Health Communication (GMHC) Vol 5, No 1 (2017)
Publisher : Universitas Islam Bandung

The human leukocyte antigens (HLAs) play important roles in the immune systems to response to various pathogens and disease among individuals. The aim of this study was analyze the HLA allele and haplotype frequencies of Southern East Asian population that show high incidence of nasopharyngeal carcinoma (NPC) to evaluate the shared HLA haplotype contribution to NPC susceptibility among the population and analyses the genetic affinities between the population. We collect information of HLA haplotype from our previous study, other published paper, and HLA database in 19 population during 2005 to 2015. Haplotype frequencies were estimated using the maximum likelihood method based on an expectation maximization algorithm with ARLEQUIN v.2.0 software. We also calculated the genetic distance among 19 Southern East Asians based on HLA allele frequency using modified Cavalli-Sforza (DA) distance method. Then, a phylogenetic tree was constructed using DISPAN software and principal component analysis (PCA) was performed using XLSTAT-PRO software. A33-B58-DR3 haplotype, tightly linked to NPC, was commonly observed in all populations, supporting the high incidence of NPC in the populations. In addition, A2-B46 haplotype also associated with NPC, was also commonly found in several population that may also have a role in the disease development. The conclusion is the HLA haplotype sharing has an important role than the HLA allele sharing. The A33-B58-DR3 haplotype and A2-B46-DR9 haplotype in this study could be related to NPC in the Southern East Asian populations. The observed haplotype needs to be tested in the real patients to confirm the assumptionPENYEBARAN HAPLOTIPE HUMAN LEUKOCYTE ANTIGEN (HLA) TERKAIT NASOPHARYNGEAL CARCINOMA (NPC) PADA POPULASI ASIA TIMUR BAGIAN SELATANHuman leukocyte antigens (HLAs) berperan penting dalam sistem imun untuk merespons berbagai patogen dan penyakit di antara individu yang berbeda. Tujuan penelitian ini menganalisis frekuensi alel dan haplotipe HLA populasi Southern East Asia yang menunjukkan insidensi yang tinggi terhadap nasopharyngeal carcinoma (NPC) untuk mengevaluasi kerentanan NPC bagi individu. Informasi haplotipe HLA dikumpulkan dari studi sebelumnya, publikasi jurnal internasional, dan database HLA pada 19 populasi dalam periode tahun 2005–2015. Frekuensi haplotipe dihitung menggunakan metode maximum likelihood berdasarkan expectation maximization algorithm menggunakan piranti lunak ARLEQUIN v.2.0. Jarak genetik di antara 19 populasi Southern East Asians dihitung menggunakan metode modified Cavalli-Sforza (DA) distance. Kemudian, pohon filogenetik dikonstruksi dengan metode neighbor-joining (NJ) menggunakan piranti lunak DISPAN. Principal component analysis (PCA) dilakukan menggunakan piranti lunak XLSTAT-PRO. Haplotipe A33-B58-DR3 terkait erat dengan NPC yang biasa terlihat di semua populasi mendukung tingginya insidensi penyakit dalam populasi. Selain itu, haplotipe A2-B46 juga terkait dengan NPC yang juga ditemukan pada beberapa populasi sehingga kemungkinan memiliki peran dalam perkembangan penyakit. Pada kasus NPC, haplotipe HLA lebih berperan dibanding dengan alel HLA. Haplotipe A33-B58-DR3 dan haplotipe A2-B46-DR9 yang ditemukan terkait dengan NPC pada populasi Southern East Asia. Haplotipe yang diamati tersebut perlu diuji pada pasien nyata untuk mengonfirmasi simpulan.

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Agus Chalid

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INDONESIA

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Agus Chalid

Contact Email gulid.p@gmail.com

Phone +6285220013654

Journal Mail Official gmhc.unisba@gmail.com

Editorial Address Jalan Hariangbanga No. 2, Tamansari, Bandung 40116

Location Kota bandung, Jawa barat INDONESIA

Abstract

Abstract

Abstract

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Abstract

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Abstract

Contact Name
Agus Chalid

Contact Email
gulid.p@gmail.com

Phone
+6285220013654

Journal Mail Official
gmhc.unisba@gmail.com

Editorial Address
Jalan Hariangbanga No. 2, Tamansari, Bandung 40116

Location
Kota bandung,

Jawa barat

INDONESIA