cover
Contact Name
Agus Chalid
Contact Email
gulid.p@gmail.com
Phone
+6285220013654
Journal Mail Official
gmhc.unisba@gmail.com
Editorial Address
Jalan Hariangbanga No. 2, Tamansari, Bandung 40116
Location
Kota bandung,
Jawa barat
INDONESIA
Global Medical and Health Communication
ISSN : 23019123     EISSN : 24605441     DOI : https://doi.org/10.29313/gmhc
Core Subject : Health, Science,
Global Medical and Health Communication is a journal that publishes research articles on medical and health published every 4 (four) months (April, August, and December). Articles are original research that needs to be disseminated and written in English. Subjects suitable for publication include but are not limited to the following fields of anesthesiology and intensive care, biochemistry, biomolecular, cardiovascular, child health, dentistry, dermatology and venerology, endocrinology, environmental health, epidemiology, geriatric, hematology, histology, histopathology, immunology, internal medicine, nursing sciences, midwifery, nutrition, nutrition and metabolism, obstetrics and gynecology, occupational health, oncology, ophthalmology, oral biology, orthopedics and traumatology, otorhinolaryngology, pharmacology, pharmacy, preventive medicine, public health, pulmonology, radiology, and reproductive health.
Articles 422 Documents
Effect of Zilgrei Method and Lumbal Massage Combination on Labor Progress During Latent Phase of First Stage of Labor in Primigravida Melati Yuliandari; Leri Septiani; Roni Rowawi; Sri Komalaningsih; Herry Garna
Global Medical & Health Communication (GMHC) Vol 8, No 2 (2020)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2480.888 KB) | DOI: 10.29313/gmhc.v8i2.5083

Abstract

The first stage of labor starts from the onset of cervical dilatation and divided into latent and active phases. The latent phase is a more prolonged phase of labor, which allows various interventions performed. Interventions and the latent phase's length may lead to anxiety and restlessness, which might contribute to prolonged labor when experienced by women in labor. A combination of the Zilgrei method and lumbar massage used to reduce labor pain. This method combines movement, change of position, breathing exercise, and the light massage performed since the first stage of labor. It expected that the work of interrelated pelvic muscles becomes harmonized; hence, the cervix will be softer, and the uterine muscles may push the fetus towards the birth canal. This study aimed to determine the effect of the Zilgrei method and lumbar massage combination on the latent phase of the first stage of labor progress in primigravida. It is a quantitative quasi-experimental study on 66 women who underwent the latent phase of the first stage of labor in independent practice of midwife the work area of Citarip Public Health Center during May–July 2019, who were divided equally into control and intervention groups. The statistical analysis used was univariate and bivariate analyses with an independent t test. The mean duration of labor in the latent phase of the first stage of labor in the control group and intervention group was 368 minutes and 307 minutes, respectively, with a difference of 61 minutes (p=0.002). Therefore, the Zilgrei method and lumbar massage combination significantly affect labor progress in the latent phase of the first stage of labor in primigravida. PENGARUH KOMBINASI METODE ZILGREI DAN PEMIJATAN LUMBAL TERHADAP PROSES KEMAJUAN PERSALINAN PADA PRIMIGRAVIDAKala I persalinan merupakan tahap serviks terbuka yang terdiri atas fase laten dan fase aktif. Fase laten mempunyai durasi persalinan lebih panjang sehingga memungkinkan banyak intervensi. Intervensi dan lama fase laten dapat menimbulkan kecemasan dan kegelisahan, apabila dialami ibu in partu dapat menjadi faktor persalinan lama. Kombinasi Metode Zilgrei dan pemijatan lumbal menjadi metode mengurangi rasa nyeri persalinan yang menggabungkan gerakan, perubahan posisi, latihan pernapasan, dan pijatan ringan yang dipersiapkan sejak kala I persalinan. Diharapkan kerja otot panggul saling berkaitan menjadi selaras sehingga serviks tidak kaku dan terdapat potensi otot rahim mendorong janin menuju jalan lahir. Tujuan penelitian ini mengetahui pengaruh kombinasi Metode Zilgrei dan pemijatan lumbal terhadap kemajuan proses persalinan kala I fase laten pada primigravida. Penelitian ini merupakan penelitian kuasi eksperimental kuantitatif pada 66 wanita yang menjalani fase laten persalinan kala I di bidan praktik mandiri (BPM) wilayah kerja Puskesmas Citarip periode Mei–Juli 2019 yang dibagi rata menjadi kelompok kontrol dan intervensi. Analisis statistik menggunakan analisis univariat dan bivariat dengan uji t independen. Durasi persalinan kala I fase laten rerata kelompok kontrol dan intervensi adalah 368 menit dan 307 menit masing-masing dengan selisih waktu 61 menit (p=0.002). Simpulan. kombinasi Metode Zilgrei dan pemijatan lumbal berpengaruh terhadap kemajuan proses persalinan kala I fase laten pada primigravida.
Determinants Associated with Discontinuation of Modern Contraceptive in East Kalimantan: a Further Analysis of Indonesia Demographic and Health Survey 2017 Ike Anggraeni; Annisa Nurrachmawati; Winardi Winardi; Hasmawati Hasmawati; Dewi Endah Ramadhani
Global Medical & Health Communication (GMHC) Vol 8, No 2 (2020)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1169.261 KB) | DOI: 10.29313/gmhc.v8i2.5426

Abstract

The national family planning program in East Kalimantan needs to achieve a larger target on modern contraceptives. Despite the fertility decline, this program still facing increasing discontinuation rates. A better understanding of the factors behind the discontinuation of a modern method would help in improving programs. This study aims to analyze the determinants of discontinuation of modern contraceptive use. This was a cross-sectional study, the dataset came from Indonesia Demographic and Health Survey 2017 of East Kalimantan Province. The sample is all couples of childbearing age between 10–49 years with marital status who have used and are still using contraception (408 samples). Descriptive analyses were used to assess the reasons for discontinuation. Multiple logistic regression was used to estimate the likelihood of discontinuation by demographic characteristics and others. The proportion of respondents who continue using modern contraceptives was 51%, against 49% discontinuation. The reasons for discontinuation were the husband’s disapproval (31%) and health problems related to side effects (26.5%). In the multivariate analysis showed maternal age, women who live in urban areas, and women with birth planning near the future will have an opportunity to discontinue in modern contraceptives. It concluded that there is still high modern contraceptive discontinuation in East Kalimantan, therefore it needed for disseminating information through entertainment-education in social media, health workers better counseling services from also better tools, and include the male participation in family planning counseling. DETERMINAN YANG BERHUBUNGAN DENGAN PUTUS PAKAI KONTRASEPSI MODERN DI KALIMANTAN TIMUR: ANALISIS LANJUT SURVEI DEMOGRAFI DAN KESEHATAN INDONESIA 2017Program keluarga berencana nasional di Kalimantan Timur perlu mencapai target yang lebih baik dalam penggunaan kontrasepsi modern. Meskipun terdapat penurunan fertilitas, namun program keluarga berencana masih menghadapi peningkatan angka putus pakai. Pemahaman yang lebih baik tentang faktor-faktor di balik putus pakai metode kontrasepsi modern akan membantu meningkatkan program. Penelitian ini bertujuan menganalisis faktor-faktor penentu putus pakai penggunaan kontrasepsi modern. Desain penelitian ini adalah cross-sectional, set data berasal dari Survei Demografi Kesehatan Indonesia 2017 untuk Provinsi Kalimantan Timur. Sampel adalah semua pasangan usia subur berusia 10–49 tahun dengan status perkawinan baik bagi yang pernah menggunakan dan masih menggunakan kontrasepsi, yaitu 408 sampel. Analisis deskriptif digunakan untuk menilai alasan putus pakai. Regresi logistik berganda digunakan untuk memperkirakan kemungkinan putus pakai berdasar atas karakteristik demografis dan lainnya. Proporsi responden yang masih terus menggunakan kontrasepsi modern adalah 51% dibanding dengan 49% putus pakai. Alasan penghentian adalah ketidaksetujuan suami (31%) dan masalah kesehatan yang berkaitan dengan efek samping (26,5%). Analisis multivariat menunjukkan usia ibu, wanita yang tinggal di daerah perkotaan, dan wanita dengan perencanaan kelahiran dalam waktu dekat akan memiliki kesempatan untuk berhenti menggunakan kontrasepsi modern. Dapat disimpulkan bahwa kejadian putus pakai kontrasepsi modern masih tinggi di Kalimantan Timur, oleh karena itu diperlukan diseminasi informasi melalui entertainment-education dalam sosial media, layanan konseling dari petugas kesehatan, serta alat bantu konseling yang lebih baik dan juga keikutsertaan pria dalam proses konseling.
Effectiveness of Al-Qur'an Tadabbur Therapy on Nulliparous Women’s Anxiety Level during Labor Nurul Auliya Kamila; Rosa Mutianingsih
Global Medical & Health Communication (GMHC) Vol 9, No 1 (2021)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (530.787 KB) | DOI: 10.29313/gmhc.v9i1.6914

Abstract

The process of pregnancy affects psychological aspects significantly. This process may lead to anxiety and inconveniences. The previous research showed that anxiety might be contributing to the labor process. These can decreased baby birth weight and increased hypothalamic-pituitary-adrenal (HPA) hormone levels which cause changes in steroid hormone production and adult fertility rates. Besides, anxiety during pregnancy impacts emotional problems, disorders of hyperactivity, decentralization, and impaired child development. Nonpharmacological therapy that has been approved in reducing anxiety is religious copings. One of the religious copings is to contemplate (tadabbur) Al-Qur'an. Al-Qur'an can treat all kinds of diseases, including anxiety disorders. This study aims to examine the effect of Al-Qur'an tadabbur therapy on reducing nulliparous anxiety levels during labor. A quasi-experimental study was conducted with a pretest-postest control group design. The sampling technique was consecutive sampling. The number of 30 third trimester nulliparous women experienced moderate-severe anxiety levels in Tanjung Karang Public Health Center, Mataram was selected to participate in this study during July–September 2020. They were divided into two groups, the intervention and control groups. The intervention group received Al-Qur'an tadabbur therapy, while the control group was not. The statistical analysis used was univariate and bivariate analyses with an independent t test. The instrument was used as the Zung Self-Rating Anxiety Scale (SAS) questionnaire. This study showed that the decrease of anxiety score in the intervention group was 26.1% higher than the control group p=0.001 (p<0.05). In conclusion, Al-Qur'an tadabbur therapy is effective in reducing anxiety levels during labor. EFEKTIVITAS TERAPI TADABBUR AL-QUR’AN UNTUK MENURUNKAN TINGKAT KECEMASAN IBU PRIMIGRAVIDA DALAM MENGHADAPI PERSALINANProses kehamilan sering kali memengaruhi aspek psikologis yang dapat menyebabkan berbagai permasalahan seperti kecemasan dan ketidaknyamanan. Selain berdampak pada proses persalinan, kecemasan juga dapat mengakibatkan penurunan berat lahir dan peningkatan aktivitas hipotalamus-hipofisis-adrenal (HHA) yang menyebabkan perubahan produksi hormon steroid dan angka fertilitas saat dewasa. Selain itu, kecemasan pada masa kehamilan berkaitan dengan masalah emosional, gangguan hiperaktivitas, desentralisasi, dan gangguan perkembangan kognitif pada anak. Terapi nonfarmakologis yang telah disetujui dalam mengurangi kecemasan adalah religious coping. Salah satu religious coping adalah dengan tadabbur Al-Qur’an. Al-Qur’an merupakan pedoman yang mampu mengobati segala macam penyakit termasuk gangguan kecemasan. Penelitian ini bertujuan menguji efek terapi tadabbur Al-Qur’an terhadap penurunan kecemasan ibu hamil primigravida dalam menghadapi persalinan. Penelitian quasi-experiment dilakukan dengan pretest-postest with control group design, teknik pengambilan sampel dengan consecutive sampling. Subjek penelitian adalah 30 ibu hamil primigravida trimester III yang mengalami kecemasan sedang–berat di wilayah kerja Puskesmas Tanjung Karang, Kota Mataram pada bulan Juli–September 2020 yang terbagi dalam 2 kelompok, yaitu kelompok intervensi yang mendapat terapi Al-Qur’an dan kelompok kontrol. Analisis data menggunakan uji t independen. Penilaian tingkat kecemasan dilakukan menggunakan kuisioner Zung Self-Rating Anxiety Scale (ZSAS). Berdasar atas hasil penelitian, penurunan tingkat kecemasan kelompok intervensi 26,1% lebih tinggi dibanding dengan kelompok kontrol dengan taraf signifikasi p=0,001 (p<0,05). Simpulan, terapi tadabbur Al-Qur’an cukup efektif untuk menurunkan kecemasan pada ibu hamil dalam menghadapi persalinan.
The Availability of Health Resources on the Performance of Maternal and Child Health Policy Implementation in East Nusa Tenggara Florentianus Tat; Irfan Irfan; Maria Magdalena Bait
Global Medical & Health Communication (GMHC) Vol 8, No 3 (2020)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (268.823 KB) | DOI: 10.29313/gmhc.v8i3.6082

Abstract

Maternal and child health problems continue to be priority health issues in Indonesia, especially in East Nusa Tenggara (NTT). The maternal mortality rate in NTT has reached 159/100,000 live births, while infant and under-five mortality rates have reached 32/1000 live births and 40/1,000 live births, respectively above the national value of 23/1000 live births and 32/1,000 live births. It indicates that the health and maternal and child health policies in NTT have not been maximally implemented. One of the causes is the lack of available health worker resources that provide health services. The research objective is to identify the effect of health resources' availability on the performance of maternal and child health policy implementation in NTT. A quantitative research method for data collection was carried out in 11 districts in NTT and 104 public health centers (pusat kesehatan masyarakat, puskesmas) towards 235 health workers from August to December 2019. The results show that the health workers were categorized as insufficient/not available (mean value of 2.64), and puskemas did not have doctors, midwives, and nurses conforming to standards. There was also inadequacy in some aspects such as budget (average value of 2.45), medical devices (average value of 2.75), medicines and medical supplies, buildings, and transport. A correlation was found between resources and the performance of maternal and child health policies (p=0.00) with a coefficient correlation of 0.546. It indicates a strong and positive correlation, which means that if there is an increase in resources, maternal and child health policy implementation will also. Partial linear regression tests showed t arithmetic=13.304 >t table 1.97, which means that H0 was rejected. It suggests a significant effect between resources and the performance of maternal and child health policy implementation in NTT. In conclusion, resources had a positively impact on the performance of maternal and child health policy in NTT. PENGARUH KETERSEDIAAN SUMBER DAYA KESEHATAN TERHADAP KINERJA IMPLEMENTASI KEBIJAKAN KESEHATAN IBU DAN ANAK DI NUSA TENGGARA TIMURPermasalahan kesehatan ibu dan anak (KIA) terus menjadi prioritas masalah kesehatan di Indonesia khususnya di Nusa Tenggara Timur (NTT). Angka kematian ibu di NTT mencapai 159/100.000 kelahiran hidup (KH), sedangkan angka kematian bayi dan balita mencapai 32/1.000 KH dan 40/1.000 KH yang masing-masing di atas nilai nasional, yaitu 23/1.000 KH dan 32/1.000 KH. Kondisi tersebut mengindikasikan bahwa penerapan kebijakan KIA di NTT belum dilaksanakan secara maksimal. Salah satu penyebabnya adalah sumber daya manusia kesehatan yang memberikan pelayanan kesehatan kurang tersedia. Tujuan penelitian adalah mengidentifikasi pengaruh ketersediaan sumber daya manusia kesehatan terhadap kinerja penerapan kebijakan KIA di NTT. Metode penelitian adalah kuantitatif. Pengumpulan data dilakukan di 11 kabupaten dan 104 pusat kesehatan masyarakat (puskesmas) pada 235 tenaga kesehatan dari bulan Agustus hingga Desember 2019. Hasil penelitian menunjukkan bahwa tenaga kesehatan dikategorikan tidak cukup/tidak tersedia (nilai rerata 2,64) dan puskesmas tidak memiliki dokter, bidan, dan perawat sesuai standar. Selain itu, terdapat juga kekurangan di beberapa aspek seperti anggaran biaya (nilai rerata 2,45), alat kesehatan (nilai rerata 2,75), obat dan perbekalan kesehatan, alat medis, bangunan, serta alat transportasi. Korelasi ditemukan antara sumber daya dan kinerja penerapan kebijakan KIA (p=0,00) dengan koefisien korelasi 0,546. Hal ini berarti korelasi cukup kuat dan positif, artinya jika sumber daya ditingkatkan maka kinerja implementasi kebijakan KIA juga meningkat. Uji regresi linier parsial menunjukkan t hitung=13,304 >t tabel 1,97 yang bermakna H0 ditolak. Hal ini menunjukkan pengaruh yang signifikan antara sumber daya dan kinerja penerapan kebijakan KIA di Provinsi NTT. Simpulan, sumber daya berpengaruh positif terhadap kinerja penerapan kebijakan KIA di NTT.
Soil-Transmitted Helminths Contamination on the Yard's Soil of the Public Elementary Schools in Bandung City Ratna Dewi Indi Astuti; Ismawati Ismawati; Hilmi Sulaiman Rathomi
Global Medical & Health Communication (GMHC) Vol 8, No 3 (2020)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (131.81 KB) | DOI: 10.29313/gmhc.v8i3.6596

Abstract

Soil contamination by soil-transmitted helminths (STH) on the schoolyard can act as reservoir STH infection for students. The STH contamination on soil due to contamination of human and animal waste which was disposed of inappropriately. This study aimed to determine the presence of STH eggs in the yard's soil of public elementary schools in Bandung city. This research was an analytic observational study with a cross-sectional approach during September 2019. This study's samples were 97 surface soil of the public elementary schoolyard in Bandung city, selected randomly. Microscopic identification is made for identifying the STH contamination on soil samples. STH contaminates about 66% yard's soil of public elementary schools in Bandung city. We identified larva nematode, Ascaris eggs, Trichuris eggs, Toxocara eggs, and Capillaria eggs. The most common STH we had found was larvae nematode (53%). There is a correlation between flood and human STH contamination on soil (p=0.015). We concluded that STH contaminates the yard's soil of the public elementary schools in Bandung city. The source of STH contamination is from human and animal waste. Flood has a role in spreading human waste on the soil. KONTAMINASI SOIL-TRANSMITTED HELMINTH PADA TANAH PEKARANGAN SEKOLAH DASAR NEGERI KOTA BANDUNGPencemaran tanah oleh soil-transmitted helminth (STH) di halaman sekolah dapat menjadi reservoir penularan STH bagi siswa. Pencemaran ini dapat terjadi akibat pengelolaan kotoran manusia dan hewan yang tidak tepat. Penelitian ini bertujuan mengetahui keberadaan telur STH di tanah pekarangan sekolah dasar negeri di Kota Bandung. Penelitian ini merupakan penelitian observasional analitik dengan pendekatan cross-sectional yang dilaksanakan pada bulan September 2019. Sampel penelitian berjumlah 97 tanah permukaan halaman sekolah dasar negeri di Kota Bandung yang dipilih secara acak. Identifikasi mikroskopis dilakukan untuk mengidentifikasi kontaminasi STH pada sampel tanah. Data banjir didapatkan dari wawancara dengan penduduk sekitar. Pencemaran STH terjadi pada 66% sampel. Kami mengidentifikasi larva nematoda, telur Ascaris, telur Trichuris, telur Toxocara, dan telur Capillaria. Jenis STH yang paling banyak ditemukan adalah larva nematoda (53%). Terdapat korelasi antara banjir dan pencemaran STH manusia di tanah (p=0,015). Kami menyimpulkan bahwa tanah pekarangan sekolah dasar negeri di Kota Bandung tercemar STH. Sumber pencemaran STH berasal dari kotoran manusia dan hewan. Banjir berperan dalam menyebarkan kotoran manusia di tanah.
The Relation of Acid Fast Bacilli with Ziehl Neelsen Staining and Histopathologic Examination of Biopsy Specimens in Extrapulmonary TB Suspected Patients Yani Triyani; Maya Tejasari; Wida Purbaningsih; Sadeli Masria; Titik Respati
Global Medical & Health Communication (GMHC) Vol 8, No 2 (2020)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (346.035 KB) | DOI: 10.29313/gmhc.v8i2.2527

Abstract

Case finding and diagnosis of extrapulmonary tuberculosis (EPTB) infection are difficult to enforce in the field because not all primary services can do it. The 2016 TB Health Guidelines, the diagnosis of EPTB, is made by clinical, bacteriological, and or histopathological examination from the biopsy. This study analyzed tissue biopsy histopathologically and bacterial of acid-fast bacilli (AFB) slide stained (by Ziehl Neelsen method) associated with histopathological features in patients diagnosed with EPTB. The study conducted in the laboratory of Al Islam Hospital Bandung from November to December 2017. Histopathological diagnosis collected from 1,304 patients, with 760 noninfectious disease patients (58%), 461 infectious disease patients (35%), and 83 (7%) infectious and non-infectious patients. EPTB found in 10% of infectious disease patients. EPTB was mostly originating in neck lymph nodes (18 of 37 patients). The histopathological diagnosis of EPTB infection found that 36 of 37 patients showed granulomas (+), but AFB stained (+) found only in 6 of 37 slides. It is possible because of granulomas is a collection of several inflammatory cells. The lesions develop granulomatous defined by necrosis. There are fewer organisms that usually exist on the periphery both inside and outside the site of infection. This important immune reaction provides the body with protection from antigen recognition, very important in the case of mycobacterial infections. In conclusion, there is no relation between AFB and histopathological examination in patients with EPTB. HUBUNGAN ANTARA BASIL TAHAN ASAM PEWARNAAN ZIEHL NEELSEN DAN HASIL PEMERIKSAAN HISTOPATOLOGI PADA PREPARAT JARINGAN BIOPSI PASIEN TUBERKULOSIS EKSTRAPARUPenemuan kasus dan diagnosis infeksi tuberkulosis ekstraparu (TBEP) sulit ditegakkan di lapangan karena tidak semua layanan primer dapat melakukannya. Berdasar atas Pedoman Kesehatan TB 2016 untuk Pengendalian TB, diagnosis TBEP dapat dilakukan dengan pemeriksaan klinis, bakteriologis, dan atau histopatologis dari biopsi. Penelitian ini menganalisis semua sediaan histopatologis dari biopsi jaringan dan menganalisis pemeriksaan bakteriologis pewarnaan basil tahan asam (BTA) (dengan metode Ziehl Neelsen) terkait dengan gambaran histopatologis pada pasien yang didiagnosis TBEP. Penelitian dilaksanakan di Laboratorium RS Al Islam Bandung dari November hingga Desember 2017. Diperoleh 1.304 pasien dengan sediaan histopatologis, diagnosis penyakit noninfeksi 760 pasien (58%), penyakit infeksi 461 pasien (35%), penyakit gabungan (infeksi dan noninfeksi) 83 pasien (7%), serta TBEP 10% dari seluruh penyakit infeksi. Sebagian besar TBEP berasal dari kelenjar getah bening leher (18 dari 37 pasien). Hasil diagnosis infeksi TBEP 36 dari 37 pasien ditemukan gambaran histopatologisnya dengan granuloma (+), tetapi dengan pewarnaan BTA (+) hanya 6 dari 37 sediaan. Hal ini mungkin karena granuloma adalah kumpulan beberapa sel inflamasi yang berkembang menjadi nekrosis sehingga lebih sedikit organisme yang biasanya terdapat di dalam maupun di luar lesi. Pembentukan granuloma merupakan reaksi kekebalan yang memberi perlindungan tubuh dari serangan antigen dalam kasus infeksi mikobakterium. Simpulan, tidak terdapat hubungan hasil pewarnaan BTA dengan pemeriksaan histopatologis pada pasien TBEP.
Effect of Gooseberry (Physalis angulata) Ethanol Extract in Wistar Rats Carrageenan-Induced Paw Oedema Ami Nurlatifah; Eka Hendryanny; Yuniarti Yuniarti
Global Medical & Health Communication (GMHC) Vol 9, No 1 (2021)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (157.077 KB) | DOI: 10.29313/gmhc.v9i1.6336

Abstract

Gooseberry is an herbaceous plant that contains flavonoids. Flavonoid is one of the secondary metabolites that have an anti-inflammatory effect. This study aims to determine the effect of using ethanol extract of gooseberry as an anti-inflammatory in carrageenan-induced paw edema. This study was in vivo experimental laboratory using a completely randomized design of 25 Wistar rats and divided into five groups. The negative control group was given carboxymethylcellulose. The positive control group has given diclofenac sodium 27 mg/200 gBW. The sample test group has given ethanol extract of gooseberry with 3.6 mg/200 gBW, 5.4 mg/200 gBW, and 7.2 mg/200 gBW dosage. Paw rat’s inflammation induced by injecting carrageenan and measured from 1st to 6th hour using a pletismometer. This study has conducted at Pharmacology Laboratory, Universitas Islam Bandung, and the Laboratory of Therapy and Pharmacology, Universitas Padjajaran, from June to September 2019. The result of average edema volume paw rats using the Kruskal-Wallis test on the 6th hour was p=0.02 (p<0.05). The Mann-Whitney test was p<0.05, showing differences between negative control and positive control and sample test groups. One-way ANOVA test on the percentage of edema inhibition between positive control and sample test group had p=0.107. It shows no significant difference. An effect of ethanol of extract of gooseberries as an anti-inflammatory with the highest percentage of edema inhibition is 5.4 mg/200 gBW dosage. The flavonoid content in gooseberries is thought to inhibit the formation of prostaglandins by inhibiting the cyclooxygenase enzyme. In conclusion, the ethanol extract of gooseberry can be anti-inflammatory. EFEK EKSTRAK ETANOL CIPLUKAN (PHYSALIS ANGULATA) TERHADAP EDEMA TELAPAK KAKI TIKUS GALUR WISTAR YANG DIINDUKSI KARAGENANCiplukan adalah tanaman herbal yang mengandung flavonoid. Flavonoid merupakan salah satu metabolit sekunder yang dapat memberikan efek antiinflamasi. Penelitian ini bertujuan mengetahui pengaruh penggunaan ekstrak etanol ciplukan sebagai antiinflamasi pada tikus yang diinduksi karagenan. Penelitian ini merupakan penelitian laboratorium eksperimental in vivo menggunakan desain rancangan acak lengkap pada 25 ekor tikus galur Wistar yang terbagi ke dalam lima kelompok. Kelompok kontrol negatif diberi carboxymethilcellulose. Kontrol positif diberi sodium diklofenak 27 mg/200 gBB. Kelompok uji diberi ekstrak etanol ciplukan dengan dosis 3,6 mg/200 gBB; 5,4 mg/200 gBB; dan 7,2 mg/200 gBB. Induksi inflamasi dilakukan dengan menginjeksikan karagenan pada telapak kaki tikus, lalu diukur menggunakan pletismometer dari jam ke-1 hingga jam ke-6. Penelitian ini dilakukan di Laboratorium Farmasi, Universitas Islam Bandung dan Laboratorium Farmasi dan Terapi, Universitas Padjajaran dari bulan Juni hingga September 2019. Volume rerata telapak kaki tikus pada jam ke-6 menggunakan Uji Kruskal-Wallis adalah p=0,02 (p<0,05). Hasil Uji Mann-Whitney diperoleh p<0,05 yang menunjukkan terdapat perbedaan bermakna antara kontrol negatif dan kontrol positif serta kelompok uji. Uji one-way ANOVA pada persentase penghambatan edema antara kontrol positif dan kelompok uji diperoleh p=0,107 yang menunjukkan tidak terdapat perbedaan yang bermakna. Terdapat pengaruh ekstrak etanol ciplukan sebagai antiinflamasi dengan persentase penghambatan edema tertinggi pada dosis 5,4 mg/200 gBB. Kandungan flavonoid pada ciplukan diduga mampu menghambat pembentukan prostaglandin dengan menginhibisi enzim siklooksigenase. Simpulan penelitian ini adalah ekstrak etanol ciplukan dapat digunakan sebagai antiinflamasi.
Knowledge Level towards Cervical Cancer Among Students of Baabul Kamil Vocational High School Windi Nurdiawan; Chrestella Odillia; Monica Risnadena Priyas; Yosefa Resti Radinda; Nabila Alifia Ahmad; Nur Agustina Ningsih; Qhonita Anif Febian; Andri Rezano
Global Medical & Health Communication (GMHC) Vol 8, No 3 (2020)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (194.897 KB) | DOI: 10.29313/gmhc.v8i3.6275

Abstract

Cervical cancer is one of the most common causes of cancer-related death in women worldwide that is mostly preventable and treatable. Knowledge and awareness of cervical cancer screening programs allow the implementation of the prevention of cervical cancer. The community service program is aimed to increase the knowledge of adolescents about cervical cancer and its screening. It was a one-group pretest-posttest quasi-experimental study to measure the level of knowledge of 45 female students of Baabul Kamil Vocational High School, Jatinangor, Sumedang. The study was conducted in May–June 2018. The participants were asked 15 questions, which was an adaptation of previous questionnaires. The program was managed by a mini-lecture that focuses on cervical cancer risk factors and early detection. Furthermore, pretest and posttest were conducted to analyze the level of knowledge on the aforementioned aspects before and after the dissemination descriptively. The participants included in this study were mostly 16 years old (67%). The average recognition of cervical cancer and its early detection was not high. The knowledge of cervical cancer among students of Baabul Kamil Vocational High School was found to be moderate. There is a significant improvement in knowledge level after dissemination. The efficacy of dissemination among female students at Baabul Kamil Vocational High School was apparent in knowledge change. However, good cancer awareness, especially cervical cancer, needs to be established and integrated through effective cancer educational programs in the school curriculum. Key intervention strategies are required to raise cancer awareness in support of taking precautions and early detection measures. TINGKAT PENGETAHUAN SISWI SMK BAABUL KAMIL TENTANG KANKER SERVIKSKanker serviks merupakan salah satu penyebab paling umum kematian terkait kanker pada wanita di seluruh dunia yang sebagian besar dapat dicegah dan diobati. Pengetahuan dan kesadaran tentang program deteksi dini kanker serviks merupakan upaya pencegahan kanker serviks. Program pengabdian pada masyakat ini bertujuan meningkatkan pengetahuan remaja mengenai kanker serviks dan deteksi dininya. Penelitian ini merupakan penelitian one-group pretest-posttest quasi-experimental untuk mengukur tingkat pengetahuan 45 siswi SMK Baabul Kamil, Jatinangor, Sumedang. Penelitian ini dilaksanakan pada bulan Mei–Juni 2018. Responden diberikan 15 pertanyaan yang merupakan adaptasi dari kuesioner sebelumnya. Program ini dilakukan melalui penyuluhan tentang faktor risiko kanker serviks dan deteksi dininya. Selanjutnya, dilakukan pretest dan posttest untuk menganalisis tingkat pengetahuan aspek-aspek tersebut sebelum dan sesudah penyuluhan secara deskriptif. Responden yang terlibat dalam penelitian ini sebagian besar berusia 16 tahun (67%). Identifikasi pengetahuan tentang kanker serviks dan deteksi dininya rerata tidak tinggi. Pengetahuan tentang kanker serviks di kalangan siswa SMKBaabul Kamil tergolong sedang. Terdapat peningkatan yang bermakna tingkat pengetahuan responden setelah diberikan penyuluhan Efektivitas sosialisasi di kalangan siswa perempuan di SMK Baabul Kamil terlihat dari perubahan pengetahuan. Namun, kesadaran kanker yang baik, khususnya deteksi dini kanker serviks perlu diatur dan diintegrasikan melalui program pendidikan kanker yang efektif dalam kurikulum sekolah. Langkah strategis diperlukan untuk meningkatkan kesadaran tentang kanker demi mendukung tindakan pencegahan dan deteksi dini.
Surgical Treatment Spine Tuberculosis by Decompression and Posterior Stabilization via Transpedicular Approach: a Retrospective Study Agus Hadian Rahim; Ahmad Ramdan; Abdul Kadir Hadar; Arnold David Pardamean; Doddy Putra Pratama Sudjana
Global Medical & Health Communication (GMHC) Vol 8, No 2 (2020)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1722.359 KB) | DOI: 10.29313/gmhc.v8i2.5377

Abstract

Clinical intervention has a central role in the outcome of spondylitis tuberculosis cases. Surgical procedures indicate to prevent neurological collapse, preservation of stability, and early mobilization. The study aims to analyze the outcome of surgical intervention in spinal tuberculosis by using a transpedicular approach. This research was a retrospective study on the Department of Orthopaedics and Traumatology in Dr. Hasan Sadikin General Hospital, Bandung, Indonesia, during 2016–2018. There were 64 subjects in this study; 35 were male, and 29 were female, ages ranged 21–60 years with a follow-up period of 12 months to 18 months. A more common site of tubercular lesion was at the thoracal lesion (44%). In this research, the patients were preoperatively categorized by the American Spinal Injury Association (ASIA) Impairment Assessment. Among them four were ASIA-A, 10 were ASIA-B, 30 were ASIA-C, 15 were ASIA-D, and five were ASIA-E. After the operative procedure, two patients were ASIA-B, five patients were ASIA-C, 17 patients were ASIA-D, and 40 were ASIA-E. Maximum patients (62%) had bony fusion grade 1. Greater than 80% of subjects had a satisfactory result. In conclusion, posterior decompression and preservation of stability with transpedicular fusion are an excellent surgical way of posterior lumbar spinal tuberculosis treatment. TINDAKAN OPERASI DEKOMPRESI DAN STABILISASI POSTERIOR MELALUI PENDEKATAN TRANSPEDIKULAR PADA TUBERKULOSIS TULANG BELAKANG: STUDI RETROSPEKTIFTindakan medis berperan penting pada manajemen akhir kasus tuberkulosis tulang belakang. Prosedur operasi dilakukan untuk mencegah perburukan defisit neurologis, menjaga kestabilan tulang belakang, dan mobilisasi dini. Tujuan penelitian ini adalah menganalisis luaran hasil tindakan operatif pada tuberkulosis tulang belakang dengan pendekatan transpedikular. Penelitian ini merupakan studi retrospektif di Departemen Orthopaedi dan Traumatologi RSUP Dr. Hasan Sadikin, Bandung, Indonesia, periode tahun 2016–2018. Terdapat 64 subjek dalam penelitian ini yang terdiri atas 35 laki-laki dan 29 perempuan, serta usia berkisar 21–60 tahun dengan masa tindak lanjut 12–18 bulan. Pada penelitian ini, lesi tuberkuler paling banyak terjadi di regio torakal (44%). Subjek penelitian dikategorikan menurut Impairment Assessment dari American Spinal Injury Association (ASIA). Preoperatif terdapat empat pasien ASIA-A, 10 pasien ASIA-B, 30 pasien ASIA-C, 15 pasien ASIA-D, dan lima pasien ASIA-E. Setelah tindakan operasi terdapat dua pasien ASIA-B, lima pasien ASIA-C, 17 pasien ASIA-D, dan 40 pasien ASIA-E. Mayoritas pasien memiliki fusi tulang grad 1 (62%). Lebih dari 80% subjek penelitian menyatakan puas setelah operasi dilakukan. Simpulan, tindakan operatif dekompresi dan stabilisasi dengan fusi transpedikular merupakan metode yang unggul dalam manajemen tuberkulosis tulang belakang.
Correlation of Thrombocytopenia and Length of Hospitalization in Dengue Child Patient Riyadi Adrizain; Ananda Hanifah Husna; Andri Rezano
Global Medical & Health Communication (GMHC) Vol 8, No 2 (2020)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (158.754 KB) | DOI: 10.29313/gmhc.v8i2.5506

Abstract

Dengue virus infection (DVI) is one of the major health problems that cause 500 thousand patients hospitalized annually. Thrombocytopenia is one of the abnormal hematologic findings that is always found in DVI patients. This study aimed to determine the correlation of thrombocytopenia and length of hospitalization in dengue child patients. This retrospective analysis study used secondary data from seven major hospitals in Bandung with a total sampling method. The inclusion criteria were patients aged 0–18 years old diagnosed with dengue fever (DF), or dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS) who was admitted from January to December 2015 and excluded when there was comorbid as well as incomplete data. The correlation was analyzed by Spearman’s rank correlation test. There were 2,025 samples from a total of 5,712 DVI cases during 2015. Among those who admitted, most of the patients experienced severe thrombocytopenia (40%) with the average length of hospitalization was 4.84 days. This result was not much different from the patients with moderate (38.1%) and mild (21.9%) thrombocytopenia who were treated for an average of 4.13 days and 4.08 days, respectively. The analysis of correlation obtained a significant relationship between thrombocytopenia and length of hospitalization despite showing a weak correlation (r=0.231, p=0.001). In conclusion, there is a weak correlation between thrombocytopenia and length of hospitalization among dengue child patients. KORELASI TROMBOSITOPENIA DENGAN LAMA RAWAT INAP PADA PASIEN ANAK TERINFEKSI VIRUS DENGUEInfeksi virus dengue (IVD) merupakan salah satu masalah kesehatan utama yang menyebabkan 500 ribu pasien dirawat di rumah sakit setiap tahun. Trombositopenia adalah salah satu temuan abnormal hematologi yang selalu ditemukan pada pasien IVD. Penelitian ini bertujuan mengetahui korelasi trombositopenia dengan lama rawat inap pada pasien anak terinfeksi virus dengue. Penelitian analitik retrospektif ini menggunakan data sekunder tujuh rumah sakit besar di Kota Bandung dengan metode total sampling. Kriteria inklusi adalah pasien anak usia 0–18 tahun yang didiagnosis demam dengue (DD), atau demam berdarah dengue (DBD), atau sindrom syok dengue (SSD) yang dirawat dari bulan Januari hingga Desember 2015. Kriteria eksklusi meliputi komorbiditas dan data rekam medis yang tidak lengkap. Analisis dilakukan dengan uji korelasi rank Spearman. Terdapat 2.025 sampel dari total 5.712 kasus IVD selama tahun 2015. Di antara yang dirawat, sebagian besar pasien mengalami trombositopenia berat (40%) dengan lama rawat inap rerata 4,84 hari. Hasil ini tidak jauh berbeda dengan pasien dengan trombositopenia sedang (38,1%) dan ringan (21,9%) yang dirawat selama rerata 4,13 hari dan 4,08 hari masing-masing. Analisis korelasi diperoleh hubungan yang bermakna antara trombositopenia dan lama rawat inap meskipun dengan nilai korelasi lemah (r=0,231; p=0,001). Simpulan, terdapat korelasi lemah antara trombositopenia dan lama rawat inap pada pasien anak terinfeksi virus dengue.