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All Journal Majalah Kedokteran Bandung Jurnal Anestesi Perioperatif Althea Medical Journal Global Medical and Health Communication Universa Medicina Syntax Literate: Jurnal Ilmiah Indonesia SOEPRA Jurnal Hukum Kesehatan Alignment: Journal of Administration and Educational Management Interdental Jurnal Kedokteran Gigi (IJKG) PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal PORKES Journal of Economics and Business UBS Jurnal Ilmiah Wahana Pendidikan ProBisnis : Jurnal Manajemen Service Management Triangle : Jurnal Manajemen Jasa Jurnal Riset Manajemen dan Bisnis Scientia Regendi Research of Service Administration Health and Sains Healthys Indonesian Journal of Cancer Business Management Media Bina Ilmiah Innovative: Journal Of Social Science Research International Journal of Law and Society ManBiz: Journal of Management and Business J-CEKI
Agus Hadian Rahim
Department Of Orthopaedic And Traumatology Faculty Of Medicine Universitas Padjadjaran / Dr. Hasan Sadikin Hospital Bandung
Religion Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Assessment of microarchitecture and crystal structure of hydroxyapatite in osteoporosis Noor, Zairin; Sumitro, Sutiman B; Hidayat, Mohammad; Rahim, Agus Hadian; Taufiq, Ahmad
Universa Medicina Vol 30, No 1 (2011)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2011.v30.29-35

Abstract

Osteoporosis is characterized by lower bone mineral density (BMD) and microarchitectural degeneration, which tends to increase bone fragility and fracture risk. Bone microstructure depends on interactions between the mineral atoms, which may perform substitution or incorporation into bone crystals, and may dynamically take over the function of calcium or may become a complementary part. The mineral atoms may also become a composite in the hydroxyapatite crystals. The aim of this study was to find an association between the bone microstructure and hydoxyapatite crystal structure in osteoporosis, in comparison to normal bone. The subjects of this study were surgery patients at the Department of Orthopedics of Ulin General Hospital in Banjarmasin and other centers. Inclusion criteria consisted of the presence of fracture of trabecular bone, normal or osteoporotic BMD values, and no past history of chronic disease. Bone was obtained from fracture patients during surgery. The characteristics of the hydroxyapatite crystals were analyzed by X-ray diffraction (XRD) and the microarchitecture by scanning electron microscopy (SEM). SEM showed degeneration of the microarchitecture of osteoporotic bone, in comparison with normal bone. On XRD there was a peak of hydoxyapatite crystals only and no other crystal phases. Diffraction patterns showed a larger crystal size in osteoporotic bone as compared to normal bone, indicating higher porosity. It may be concluded that there is a difference in crystal size and morphologic distribution of hydoxyapatite in osteoporotic bone, determining bone microarchitecture.
Relationship between Types of Cervical SpineTrauma and Occurrence of Neurological Deficits Anwar, Syaiful; Rahim, Agus Hadian; Anwary, Farhan
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (166.86 KB) | DOI: 10.15850/amj.v4n2.1084

Abstract

Background: About 3,500 people died each year due to neck injury, according to a study in the USA. Trauma at cervical spine level causes injury in soft tissue, cervical vertebrae, and spinal cord that can cause neurological deficits. The aim of this study was to analyze the relationship between type of cervical trauma and the occurrence of neurological deficits.Methods: An analytic study was carried out to 121 medical records of patients  diagnosed with cervical spine trauma at Dr. Hasan Sadikin General Hospital Bandung in the period of January 2010−December 2012.  Data were classified according to age, sex, period of initial visit to hospital, mechanism of trauma, cervical trauma type, fracture’s or dislocation’s location (without any other vertebral injury) and neurological status. The collected data were analyzed using Chi-Square test and presented in tables.Results: There were 121 cases of cervical spine trauma. Most patients were male and in the productive age group (30−44 years). Most of the initial visits to the hospital were in 2010 and most of the mechanism was traffic accident (46.28%), while soft tissue injury was the most common type of cervical trauma (54.54%) and lower cervical vertebrae was the most common location of fractures or dislocations (76.36%). Sixty two patients were recorded with neurological deficits. Chi-Square test of relationship between  the type of cervical trauma and the occurrence of neurological deficit was statistically significant (p=0.000).Conclusions: There is relationship between the type of cervical trauma and occurrence of neurological deficits. DOI: 10.15850/amj.v4n2.1084
Karakteristik Atom Mineral pada Osteoporosis dengan Arsitektur Porosis dan Nonporosis Noor, Zairin; Sumitro, Sutiman B.; Hidayat, Mohammad; Rahim, Agus Hadian
Majalah Kedokteran Bandung Vol 45, No 1 (2013)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (651.505 KB)

Abstract

Terdapat hasil yang bervariasi dalam peningkatan bone mineral density (BMD) akibat asupan kalsium mengindikasikan keterlibatan atom mineral lain dalam perkembangan struktur tulang. Kuantitas atom mineral tulang yaitu kadar atom mineral dalam struktur tulang. Penelitian ini bertujuan untuk membandingkan karakteristik atom mineral pada gambaran arsitektur (scanning electron microscope/SEM) porosis dibandingkan dengan nonporosis. Sepuluh penderita osteoporosis dengan gambaran SEM porosis dan tujuh penderita gambaran SEM nonporosis terlibat dalam penelitian ini. Tulang yang diambil ketika operasi fraktur dianalisis mikrostruktur dengan SEM dan karakter atom mineral tulang dengan X-ray fluorescence (XRF). Pemeriksaan SEM dan XRF dilaksanakan di Laboratorium Fisika Universitas Negeri Malang. Penelitian dilakukan mulai Agustus 2010 sampai Januari 2011. Uji t dilakukan untuk menentukan perbedaan kadar mineral tulang. Hasil SEM menunjukkan perbedaan porositas dan integritas trabekular antara SEM porosis dan SEM nonporosis. Analisis XRF didapatkan komposisi atom yang lebih tinggi pada tulang SEM nonporosis yaitu P, S, Fe, Ni, Cr, Pb, dan Si. Sebaliknya, komposisi atom yang lebih tinggi pada tulang SEM porosis adalah Cu, Zn, Ca, dan Mo. Perbedaan komposisi atom tersebut tidak berbeda secara bermakna (p>0,05). Simpulan, perkembangan porositas pada osteoporosis tidak didasari oleh kuantitas atom mineral tulang. [MKB. 2013;45(1):23–7]Kata kunci: Arsitektur, atom mineral, komposit, osteoporosisMineral Atomic Characteristic on Porotic and Non Porotic Architecture  of OsteoporosisThere was variance result in increased bone mineral density (BMD) due to calcium intake which indicates involvement of another mineral atomic in bone structure development. Bone mineral atomic quantity is the level or concentration of mineral atomic in bone structure. Aim of this study was to compare mineral atomic characteristic in architecture (scanning electron microscope/SEM) porotic and non porotic figure. Ten osteoporosis patients with porotic SEM and seven non porotic SEM patients were involved in this study. Bone which was obtained from fracture surgery was analyzed for microstructure by SEM and for bone atomic mineral characteristic by X-ray fluorescence (XRF). Analysis of SEM and XRF were done in Physics Laboratory State University of Malang. This study was done from August 2010 to January 2011. t-test was done to analyse the difference of atomic mineral level. Scanning electron microscope result showed the difference in porosity and trabecular integrity between porotic and non porotic SEM. Analysis of XRF showed atomic composition was higher in porotic SEM such as P, S, Fe, Ni, Cr, Pb and Si. Conversely atomic composition such as Cu, Zn, Ca, and Mo, was higher in non porotic SEM. There was no significant difference between each groups (p>0.05). In conclusion, the development of porocity in osteoporosis is not depend on bone mineral atomic quantity. [MKB. 2013;45(1):23–7]Key words: Architecture, composite, mineral atomic, osteoporosis DOI: http://dx.doi.org/10.15395/mkb.v45n1.96
Keberhasilan Fusi Tulang Belakang pada Spondilitis Tuberkulosis Rahim, Agus Rahadian; Tiksnadi, Bambang; Hidayat, Nucki N.; Ramdan, Ahmad
Majalah Kedokteran Bandung Vol 43, No 3
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Fusi tulang belakang pada spondilitis tuberkulosis bertujuan untuk menghilangkan sumber infeksi, koreksi deformitas, dan mengatasi komplikasi neurologis. Data tingkat keberhasilan fusi ini masih belum tersedia. Kendala lain adalah harga instrumentasi bermerek untuk operasi fusi tulang belakang sangat mahal. Penelitian studi kohort retrospektif ini untuk evaluasi keberhasilan fusi tulang belakang pada spondilitis tuberkulosis di Rumah Sakit Dr. Hasan Sadikin, Bandung tahun 2005–2009. Didapatkan 115 kasus spondilitis tuberkulosis yang dioperasi terdiri atas 34 (29,3%) kasus anterior decompresion spinal fusion (ADSF) dan 81 (70,7%) kasus dengan menggunakan instrumentasi posterior. Dari 81 kasus tersebut, terdapat 3, 27, 26, dan 19 orang berturut-turut mengalami fusi tulang belakang setelah 4, 3, 2, dan 1 tahun pascaoperasi. Hanya 6 kasus yang belum mengalami fusi. Tingkat keberhasilan fusi tulang belakang pada kasus spondilitis tuberkulosis terbukti tinggi, 93%. Selain itu, instrumentasi lokal dapat digunakan sebagai alternatif instrumentasi yang bersifat cost effective untuk tindakan operasi fusi tulang belakang pada kasus spondilitis tuberkulosis dengan p=0,63. Sebagai kesimpulan, kasus spondilitis tuberkulosis yang memerlukan tindakan operasi fusi tulang belakang dapat ditangani dengan baik di RS Dr. Hasan Sadikin, dengan tingkat keberhasilan tinggi dan cost effective. [MKB. 2011;43(3):134–9].Kata kunci: Fusi tulang belakang, spondilitis tuberkulosisSuccessful Rate of Spinal Fusion in Spondylitis TuberculosisSpinal fusion for spondylitis tuberculosis is performed to diminish infection source, correct deformity and overcome neurologic complication. Data of spinal fusion rate has not been available yet. The other problem is that branded instrumentation price is very expensive. The aim of this retrospective cohort study was to evaluate successful rate of spinal fusion in spondylitis tuberculosis performed in Dr. Hasan Sadikin General Hospital, Bandung year 2005–2009. There were 115 cases of spondylitis tuberculosis which treated by operations, 34 cases (29.3%) with anterior decompresion spinal fusion (ADSF) and 81 cases (70.7%) using posterior instrumentation. From those 81 cases, 3, 27, 26, and 19 patients after surgery 4, 3, 2, dan 1 year had spinal fusion, consecutively. Only 6 cases who had not fused yet. The successful rate of spinal fusion in spondylitis tuberculosis, Bandung was proved to be high, 93%, and local instrument product could be used as a costly effective and good alternative treatment in operative management of spondylitis tuberculosis with p=0.63. As a conclusion, spondylitis tuberculosis cases which need spinal fusion can be well treated in Dr. Hasan Sadikin Hospital with high successful rate and cost effective. [MKB. 2011;43(3):134–9].Key words: Spinal fusion, spondylitis tuberculosis DOI:  http://dx.doi.org/10.15395/mkb.v43n3.59
Iron as Preoperative Antituberculosis Supplement Increases Interleukin-12 Level in Spinal Tuberculosis and Iron Deficiency Patients Anggi Fauziani; Nucki Nursjamsi Hidajat; Ahmad Ramdan; Agus Hadian Rahim
Jurnal Anestesi Perioperatif Vol 8, No 1 (2020)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (552.14 KB) | DOI: 10.15851/jap.v8n1.1965

Abstract

Iron deficiency remains the most prevalent micronutrient deficiency worldwide. Iron deficiency in TB patients, causes a poor outcome, reccurency, and treatment failure. Iron supplements on TB patients with iron deficiency will activate macrophage-derived monocytes (MDM) and interferon-gamma (IFN-γ), with a positive feedback mechanism pushing interleukin-12 (IL-12). This study is a single-blind randomized control trial comparing the effectivity of preoperative iron supplementation in IL-12 level between two different groups in Dr. Hasan Sadikin General Hospital Bandung, conducted from November 2018 until March 2019. Respondents are those having Spondylitis TB, with sTfR > 21,7 pg/mL and IL-12 <41 pg/mL, intensive phase antituberculosis drugs category 1. The experimental group, comprised 17 respondents, was treated with 2RHZE and 357mg iron (III) hidroxy polymaltosa. The control group was treated with 2RHZE. The sTfR and IL-12 levels were performed before and after treatment. The increase of IL-12 in the experimental group was +364,53% higher than in the control group (p<0.05). The decrease of sTfR in the experimental group was -60,68% higher than in the control group (p<0.05). The result of the Pearson correlation test was a coefficient correlation of - 0,73, this showed that a decrease in the sTfR level correlated with an increase in the Il-12 level. Iron supplement in Spondylitis TB with iron deficiency in the experimental group increases the IL-12 level. Preoperative iron supplementation on spondylitis TB with iron deficiency, increases the immune system with higher levels of IL-12.Perbedaan Kadar IL-12 pada Terapi Pre-Operatif Spondilitis TB dengan Defisiensi Zat Besi yang diberikan Suplementasi Zat BesiDefisiensi Fe merupakan defisiensi mikronutrien paling sering di seluruh dunia, jika terjadi pada penderita TB akan meningkatkan risiko prognosa buruk, rekurensi, MDR, dan gagal terapi. Suplementasi besi pada tuberkulosa dengan defisiensi besi akan meningkatkan sistem imun dengan mengaktivasi macrophage derived monocyt, dan interferon-gamma, dengan mekanisme umpan balik positif memacu interleukin-12. Single blind randomized control trial untuk membandingkan efektivitas Fe terhadap kenaikan IL-12 pada terapi preoperatif spondilitis TB di RSHS periode Nopember 2018- Maret 2019. Metode sampling;consecutive sampling. Subjek sebanyak 34 orang; Penderita spondilitis TB, sTfR >21,7 pg/ml dan IL-12< 41 pg/mL. fase intensif OAT kategori 1sesuai dengan standar WHO. Kelompok eksperimen, 17responden diterapi 2 RHZE + tablet iron (III) hidroksi polimaltosa357 mg selama 2 bulan. Kelompok kontrol 17 responden diterapi 2RHZE. Peningkatan IL-12 pada kelompok eksperimen sebesar +364,53% lebih besar dari kelompok kontrol (p<0,05) dan; Penurunan kadar sTfR pada kelompok eksperimen sebesar –60,68% (p<0,05) lebih besar dari kontrol. Uji korelasi sTfR dan IL-12 dengan Pearson ; korelasi -0,763, menunjukkan korelasi kuat antara penurunan sTfR dan kenaikan nilai IL-12. Suplementasi Fe pada terapi preoperatif spondilitis TB dengan defisiensi Fe meningkatkan respon imun yang ditandai dengan meningkatnya IL-12.
Relationship between Types of Cervical SpineTrauma and Occurrence of Neurological Deficits Syaiful Anwar; Agus Hadian Rahim; Farhan Anwary
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (166.86 KB) | DOI: 10.15850/amj.v4n2.1084

Abstract

Background: About 3,500 people died each year due to neck injury, according to a study in the USA. Trauma at cervical spine level causes injury in soft tissue, cervical vertebrae, and spinal cord that can cause neurological deficits. The aim of this study was to analyze the relationship between type of cervical trauma and the occurrence of neurological deficits.Methods: An analytic study was carried out to 121 medical records of patients  diagnosed with cervical spine trauma at Dr. Hasan Sadikin General Hospital Bandung in the period of January 2010−December 2012.  Data were classified according to age, sex, period of initial visit to hospital, mechanism of trauma, cervical trauma type, fracture’s or dislocation’s location (without any other vertebral injury) and neurological status. The collected data were analyzed using Chi-Square test and presented in tables.Results: There were 121 cases of cervical spine trauma. Most patients were male and in the productive age group (30−44 years). Most of the initial visits to the hospital were in 2010 and most of the mechanism was traffic accident (46.28%), while soft tissue injury was the most common type of cervical trauma (54.54%) and lower cervical vertebrae was the most common location of fractures or dislocations (76.36%). Sixty two patients were recorded with neurological deficits. Chi-Square test of relationship between  the type of cervical trauma and the occurrence of neurological deficit was statistically significant (p=0.000).Conclusions: There is relationship between the type of cervical trauma and occurrence of neurological deficits. DOI: 10.15850/amj.v4n2.1084
Surgical Treatment Spine Tuberculosis by Decompression and Posterior Stabilization via Transpedicular Approach: a Retrospective Study Agus Hadian Rahim; Ahmad Ramdan; Abdul Kadir Hadar; Arnold David Pardamean; Doddy Putra Pratama Sudjana
Global Medical & Health Communication (GMHC) Vol 8, No 2 (2020)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1722.359 KB) | DOI: 10.29313/gmhc.v8i2.5377

Abstract

Clinical intervention has a central role in the outcome of spondylitis tuberculosis cases. Surgical procedures indicate to prevent neurological collapse, preservation of stability, and early mobilization. The study aims to analyze the outcome of surgical intervention in spinal tuberculosis by using a transpedicular approach. This research was a retrospective study on the Department of Orthopaedics and Traumatology in Dr. Hasan Sadikin General Hospital, Bandung, Indonesia, during 2016–2018. There were 64 subjects in this study; 35 were male, and 29 were female, ages ranged 21–60 years with a follow-up period of 12 months to 18 months. A more common site of tubercular lesion was at the thoracal lesion (44%). In this research, the patients were preoperatively categorized by the American Spinal Injury Association (ASIA) Impairment Assessment. Among them four were ASIA-A, 10 were ASIA-B, 30 were ASIA-C, 15 were ASIA-D, and five were ASIA-E. After the operative procedure, two patients were ASIA-B, five patients were ASIA-C, 17 patients were ASIA-D, and 40 were ASIA-E. Maximum patients (62%) had bony fusion grade 1. Greater than 80% of subjects had a satisfactory result. In conclusion, posterior decompression and preservation of stability with transpedicular fusion are an excellent surgical way of posterior lumbar spinal tuberculosis treatment. TINDAKAN OPERASI DEKOMPRESI DAN STABILISASI POSTERIOR MELALUI PENDEKATAN TRANSPEDIKULAR PADA TUBERKULOSIS TULANG BELAKANG: STUDI RETROSPEKTIFTindakan medis berperan penting pada manajemen akhir kasus tuberkulosis tulang belakang. Prosedur operasi dilakukan untuk mencegah perburukan defisit neurologis, menjaga kestabilan tulang belakang, dan mobilisasi dini. Tujuan penelitian ini adalah menganalisis luaran hasil tindakan operatif pada tuberkulosis tulang belakang dengan pendekatan transpedikular. Penelitian ini merupakan studi retrospektif di Departemen Orthopaedi dan Traumatologi RSUP Dr. Hasan Sadikin, Bandung, Indonesia, periode tahun 2016–2018. Terdapat 64 subjek dalam penelitian ini yang terdiri atas 35 laki-laki dan 29 perempuan, serta usia berkisar 21–60 tahun dengan masa tindak lanjut 12–18 bulan. Pada penelitian ini, lesi tuberkuler paling banyak terjadi di regio torakal (44%). Subjek penelitian dikategorikan menurut Impairment Assessment dari American Spinal Injury Association (ASIA). Preoperatif terdapat empat pasien ASIA-A, 10 pasien ASIA-B, 30 pasien ASIA-C, 15 pasien ASIA-D, dan lima pasien ASIA-E. Setelah tindakan operasi terdapat dua pasien ASIA-B, lima pasien ASIA-C, 17 pasien ASIA-D, dan 40 pasien ASIA-E. Mayoritas pasien memiliki fusi tulang grad 1 (62%). Lebih dari 80% subjek penelitian menyatakan puas setelah operasi dilakukan. Simpulan, tindakan operatif dekompresi dan stabilisasi dengan fusi transpedikular merupakan metode yang unggul dalam manajemen tuberkulosis tulang belakang.
Bone microstructure and atomic periodic disharmonization in osteoporosis Zairin Noor; Mohammad Hidayat; Agus Hadian Rahim; Sutiman B. Sumitro
Universa Medicina Vol. 31 No. 2 (2012)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2012.v31.96-104

Abstract

BackgroundBoth cortical and cancellous bone display a complex, porous microstructure whose properties depend on the macrostructure of bone as well as age and health of the individual. The aim of this study was to compare the microstructure and characteristics of mineral atoms in osteoporotic and normal bone. MethodsA prospective laboratory experimental study was conducted from August to December 2010 at several hospitals in Banjarmasin. Twenty patients with osteoporosis and twenty six normal patients were involved in this study. Bone obtained from surgery was analyzed for microstructure by scanning electron microscopy (SEM), while mapping of mineral atoms was performed by means of SEM-Energy dispersive X-ray spectroscopy (SEM-EDAX) at the Brawijaya University, Malang.     ResultsThe osteoporotic subjects with mean age of 64.65 ± 16.41 years were older than the normal bone subjects with mean age of 39.38 ± 17.16 years. The body mass index was similar in both groups of subjects. From SEM-EDAX results, three patterns of mineral atoms were apparent in osteoporotic and normal bone. In osteoporotic bone, these patterns were indicative of a disordered substitution or incorporation process. SEM results showed degeneration of microarchitecture (resorption cavities, perforations, and prominent granules) in osteoporotic but not in normal bone. There was a significant difference in microstructure between osteoporotic and normal bone, which was caused by differences in atomic properties.    ConclusionsMicrostructural abnormalities of bone and disharmonization of mineral atoms in the periodic system were found in osteoporosis.
REKAM MEDIS ODONTOGRAM SEBAGAI ALAT IDENTIFIKASI DAN KEPENTINGAN PEMBUKTIAN DI PENGADILAN . Trisnowahyuni; Agus Hadian Rahim; Eddie Imanuel Doloksaribu
SOEPRA Vol 3, No 1 (2017)
Publisher : Universitas Katolik Soegijapranata Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (388.808 KB) | DOI: 10.24167/shk.v3i1.704

Abstract

Identifikasi melalui rekam medis odontogram bertujuan untuk memenuhi persyaratan sebagai tenaga professional dokter, dokter gigi ataupun tenaga kesehatan lainnya di dalam pembuatan rekam medis. Pelaksanaannya harus sesuai dengan peraturan yang telah ditetapkan, selain banyak manfaatnya rekam medis ini dapat dipakai sebagai alat bukti di pengadilan. Saat ini belum semua dokter gigi maupun perawat gigi di Indonesia melakukan pencatatan rekam medis odontogram secara benar. Masih belum adanya keseragaman dalam tata cara penulisan maupun pengistilahan yang digunakan dalam pencatatan rekam medis odontogram sehingga menimbulkan kesalahpahaman saat rekam medis tersebut dimanfaatkan dalam suatu proses hukum. Standar Operasi Prosedur mengenai rekam medis odontogram perlu diterapkan dan dilaksanakan pada setiap pelayanan kesehatan baik instansi pemerintah, swasta maupun pratik perseorangan dengan standar Nasional maupun Internasional secara manual, digital maupun secara elektronik.
Multidisciplinary Management of a Rare Case of a Huge LowGrade Chondrosarcoma of the Lumbar Spine: A Case Report Samuel Jason Rolando Tua; Hendy Rachmat Primana; Agus Hadian Rahim; Ahmad Ramdan; Herry Herman
Indonesian Journal of Cancer Vol 14, No 4 (2020): December
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1102.842 KB) | DOI: 10.33371/ijoc.v14i4.740

Abstract

Introduction: Chondrosarcoma is the second most common primary bone sarcoma and arising in the spine. It is estimated to be 2% to 12% in incidence from various series. The use of neoadjuvant and adjuvant chemotherapy for chondrosarcomas is controversial. Low- and intermediate-grade chondrosarcomas respond poorly to chemotherapy. Although not much data on the efficacy of chemotherapy in the treatment of high-grade chondrosarcomas, it should be considered in any young patient with a high-grade tumor. Radiation is recommended when anything other than wide excision is performed for chondrosarcoma of any grade.Case Presentation: A 24-year old female presented to the clinic with a chief complaint of persistent low back pain and a lump in her back. Initially, the lump was the size of a tennis ball three years ago. At the time of the examination, the lump was at the size of a volleyball about 65 x 63 x 58 centimeters. Systemic and general examinations were unremarkable. There were no comorbid conditions. From the results of the Clinicopathological Conference conducted by neurologists, pathologists, radiologists, orthopedic spine and oncology surgeons, it is advisable to conduct investigations such as x-rays, CT scans, MRI, biopsy, and surgery is recommended for evaluation of expansion of chondrosarcoma, evolving the spinal cord, and for resection of tumors.Conclusion: Early diagnosis and complete resection of tumor and treatment of relevant symptoms represent a viable treatment for this rare disorder to achieve increased life expectancy, low recurrence of tumor, and improvement of quality of life.
Co-Authors . Trisnowahyuni A. Rohendi A. RohendiH A.A. Ketut Agung Cahyawan W Abdul Kadir Hadar Ahmad Arif Nurrahman Ahmad Ramdan Ahmad Ramdan Ahmad Ramdan Ahmad Ramdan Ahmad Rizal Ganiem, Ahmad Rizal Ahmad Taufiq Anggi Fauziani Anisah Anisah Ari indra Susanti Arnold David Pardamean Bambang Tiksnadi Carolus Ronald Dadang Kusnadi Dey Ravena Dhewy, Galuh Kusuma Doddy Putra Pratama Sudjana Dwi Permana Putra Eddie Imanuel Doloksaribu Egypti, Lubna Ekwandini, Dhona Rizky Erliany Syaodih Farhan Anwary Farhan Anwary Ghuna Arioharjo Utoyo Haryadi, Pande Made Doddy Hendy Rachmat Primana Herry Herman idyasanthi, Komang Ayu Sri W Iwan Ariyanto Johanes C. Mose Kahar Mulyani Kevin Aldio Putra Khotimah , Khusnul Laksono Trisnantoro Mohammad Hidayat Mohammad Hidayat Muhammad Syafril Firdaus Muhardi Nadia Brigita Cahayani Ningsih, Desy Kartika Nucki N. Hidayat Nucki Nursjamsi Hidajat Nugraha, Fitrahadi Nugraha, Yudi Purnama Purwadhi Purwadhi Purwadhi Purwadhi Rahayu, Tri Wachyuni Rinawati Rinawati Sagala, Rolles Samuel Jason Rolando Tua Setiawanto, Teguh Sibarani, Tagor Sofiati Dian Sri Suwarsi Sujarwinata, Tio Hara Sundari Sundari Susiarno , Hadi Sutiman B. Sumitro Sutiman B. Sumitro Tarawan , Vita Murniati Tri Yuyun Apriliandika Simak Veranita , Mira Veranita, Mira Widia Hafsyah Sumarlina Ritonga, Widia Hafsyah Sumarlina Yohanes Firmansyah Yoyos Dias Ismiarto Yusnan Yusuf Zairin Noor Zairin Noor