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INDONESIA
ODONTO Dental Journal
Published by Universitas Islam Sultan Agung
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Arjuna Subject : -
Articles 11 Documents
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Search results for , issue "Vol 7, No 1 (2020): July 2020" : 11 Documents clear
COWHIDE GELATIN NANOPARTICLES AND TITANIUM-PREPARED PLATELET-RICH FIBRIN POTENTIAL IN PERIODONTITIS HEALING PROCESS Kurniawati, Atik; Saputra, Dwi Riski; Sari, Dewi Yunita; Amanitha, Indhi Cinthiya; Masruroh Hariyati, Siti Nurul
Odonto : Dental Journal Vol 7, No 1 (2020): July 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.7.1.73-81

Abstract

Introduction: Based on epidemiological data, the periodontitis prevalence in Indonesia reached 96.58%. Periodontitis is a periodontal disease caused by specific microorganisms causing attachment loss, alveolar bone resorption, and periodontal pocket. The pocket which is more than 6 mm couldn’t be carried out using standard care. Therefore bone grafting is needed to fix the bone defect. Cowhide Gelatin nanoparticle (GNPs) combined with Titanium-Prepared Platelet-Rich Fibrin (T-PRF) is an innovative healing of periodontitis. Objective: To review the potential of cowhide gelatin nanoparticles combined with titanium-prepared platelet-rich fibrin (T-PRF) as an innovation in the healing of periodontitis defects. Literature review: Cowhide GNPs are the main ingredients for the bone replacement, which are nano-sized, biocompatible, bioactive, osteoconductive, non-toxic, and have a porous structure that supports the drug-delivery process. T-PRF contains platelets, fibrin, growth factors that can stimulate bone regeneration. Discussion: GNPs support the attachment and proliferation of osteoblast cells and the formation of mineralized bone matrix. The contents of T-PRF, which are fibrin, platelets, and growth factors, one of TGF-β1 will produce bone formation and periodontal healing in the large number. Moreover, T-PRF has leukocyte-fibrin, which may give an antibacterial effect. Thus, GNPs combined with T-PRF have more potent properties that support each other in carrying out their functions to stimulate the healing process. Conclusion: The combination of cowhide gelatin nanoparticles (GNPs) and titanium-prepared platelet-rich fibrin (T-PRF) has the potential to be effective in bone regeneration in periodontitis defects.
PROPERTIES OF COMPOSITE RESIN ALKASIT AND ZIRCONIA-REINFORCED GLASS-IONOMER CEMENT IN DIFFERENT STORAGE Clarinda Vinindya; Cynthia Pratiwi; Yosi Kusuma Eriwati; Siti Triaminingsih; Decky J Indrani
ODONTO : Dental Journal Vol 7, No 1 (2020): July 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.7.1.40-47

Abstract

Background: The temperature and salivary pH in a person's mouth are highly dynamic (e.g., before, during, and after eating) and so restorations in a cavity must be resilient to these variable conditions. Temperature and immersion conditions affect the mechanical properties of a restoration. This study aimed to determine the effect of environmental conditions on diametral tensile strength (DTS) and surface microhardness of a resin composite with alkaline fillers or zirconia–reinforced glass ionomer cement (Zr-reinforced GIC). Method: Thirty specimens of a resin composite with alkaline fillers (Cention-N, Ivoclar-Vivadent, Lichtenstein) and 30 specimens with zirconia-reinforced GIC (Zirconomer, Shofu, Japan) were stored at different conditions (23°C and 37°C; with and without immersion in water) for 24 hours. DTS was tested with a Universal Testing Machine (AGS-X series, Shimadzu, Japan) and surface microhardness was tested with a Vickers Microhardness tester (HMV-G Series Micro Vickers Microhardness Tester, Shimadzu, Japan). Data were analyzed statistically using a one-way ANOVA test (and Shapiro-Wilk test. Result: The values of microhardness and DTS increased significantly both for the composite resin alkasite and zirconia-reinforced GIC with increasing temperature in the groups without immersion. However, there was a significant decrease in microhardness and DTS after immersion in distilled water at 37°C for both the composite resin alkasite and zirconia-reinforced GIC. Conclusion: It can be concluded that storage conditions affect the microhardness and DTS of resin composite Alkasite and Zirconia-reinforced GIC
STUDY ANALYSIS OF ORAL TUBERCULOSIS LESION IN SOUTH KALIMANTAN, INDONESIA Maharani Laillyza Apriasari; Monita Valentine Silalahi; Isnur Hatta; Juliyatin Putri Utami
ODONTO : Dental Journal Vol 7, No 1 (2020): July 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.7.1.1-8

Abstract

Background: Tuberculosis is an infectious disease which is the second-largest cause of death in the world after HIV / AIDS. Tuberculosis caused by Mycobacterium tuberculosis that usually attacks the lungs but can manifest in the oral mucosa. Clinical manifestations of oral Tuberculosis related to age, sex, duration of treatment, systemic disease, and Multi-Drug Resistant therapy. There is no research on descriptive studies of oral manifestations of tuberculosis patients in South Kalimantan, specifically in Banjarmasin. This study aims to analyze the clinical manifestations of oral Tuberculosis descriptively in South Kalimantan, Indonesia. Method: This was a descriptive analysis with cross-sectional study design, based on history and clinical oral examination. It was used 30 respondents by purposive sampling method. Data were analyzed by Chi-square (p<0.05). Results: During treatment, it showed the correlation between xerostomia and systemic disease (diabetes mellitus and HIV/AIDS) are (p=0.007) and a correlation between xerostomia and duration of treatment (p=0.024). The correlation between candidiasis and systemic disease (p=0.024). The correlation between angular cheilitis and age, sex, duration of treatment, systemic disease, and Multi-Drug Resistant therapy (p>0.05). The clinical manifestations of oral Tuberculosis are xerostomia, candidiasis, and angular cheilitis.Conclusion: The duration of treatment and the systemic diseases are associated with xerostomia and candidiasis in the oral cavity of TB patients.
METRONIDAZOLE GEL EFFECT ON RATS WITH BACTERIA-INDUCED PERIODONTITIS Muhamat Muhtar S. Abdurrohman; R. Rama Putranto
ODONTO : Dental Journal Vol 7, No 1 (2020): July 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.7.1.48-52

Abstract

Background: Periodontitis is an inflammatory disease in the periodontal tissue and causes progressive tissue damage. Tissue Inhibitor of Matrix Metalloproteinases-1 (TIMP-1) is directly responsible for the pathogenesis of periodontal diseases. Topical application of the metronidazole gel as a therapy for periodontal diseases can be used for additional therapy. This study aimed to analyze the effect of Metronidazole gel on periodontitis based on TIMP-1 levels in bacteria-induced periodontitis in rats. Methods: Twenty Sprague Dawley rats weighing 170-200 gram aged two months. Rats were divided into two groups: the control group and Metronidazole gel (Ti-es Metronidazole gel, 0.45 mg). Metronidazole gel was topically applied to the gingival sulcus. The gingival crevicular fluid sample was taken on day 3 with periopaper subjected to the Tissue Inhibitor of Matrix Metalloproteinase-1 level evaluation using the ELISA Method. Results: Normal reference Tissue Inhibitor of Matrix Metalloproteinase 1 levels gingival crevicular fluid 0.156-10 ng/ml. Tissue Inhibitor of Matrix Metalloproteinase 1 gingiva crevicular fluid in control and metronidazole gel was 1.34 ng/ ml and 3.57 ng /ml. There was a significant difference between control and metronidazole gel group (p<0.005)Conclusion: The Application of Metronidazole gel affects TIMP-1 levels in periodontitis.
CHARACTERIZATION AND POTENCY OF STICHOPUS HERMANNI ETHANOL EXTRACT ON ORAL WOUND HEALING Rima Parwati Sari; Stevanus Candra Sugiarto Budijono
ODONTO : Dental Journal Vol 7, No 1 (2020): July 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.7.1.9-17

Abstract

Background: Stichopus hermanni contains protein, glycosaminoglycans and EPA-DHA, which accelerate oral wound healing. Ethanol is solvent with universal nature and frequently used in the extraction. This study aims to know the characterization and potency of Stichopus hermanni in oral wound healing. Methods: Stichopus hermanni was dried by freeze-dry method and extracted using ethanol solvent. Characterization was examined the levels of protein, glycosaminoglycans and EPA-DHA. In vivo, male wistar rats made traumatic ulcer at the lower labial mucosa by using thermal burn. Thirty-two rats are divided into four groups (n=8), negative control group (K), positive control group (AH) was given hyaluronic acid gel 0.2%, and treatment groups were given Stichopus hermanni 60%-80% (SH60-SH80) gel. The ulcer formed was given gel for four days. The rat’s labial mucosa was measured. The difference between the first and fourth day is tabulated. Data were analyzed by Anova and Tukey-HSD tests. Results: The result of Spectrophotometry show the contents of protein (19.39), glycosaminoglycans (2.79–3.98). The result of in vivo showed a significant difference in ANOVA test (K=1.07; AH=1.27; SH60=1.89; SH80=1.66). In the Tukey-HSD test, the SH60 group shows a significant difference between K and AH groups. Conclusion: Stichopus hermanni ethanol extract gel contain protein and Glycosaminoglycans and potency for oral wound healing.
BAY LEAF (SYZYGIUM POLYANTHUM) EXTRACT EFFECT ON IL-10 EXPRESSION IN ORAL ULCER Shafia, Arina; Mujayanto, Rochman; Feranisa, Anggun
Odonto : Dental Journal Vol 7, No 1 (2020): July 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.7.1.53-59

Abstract

ANTIBACTERIAL EFFECT OF WHITE POMEGRANATE PEEL EXTRACT (PUNICA GRANATUM L) AGAINST STREPTOCOCCUS SANGUINIS Diniasti, Muthiah; Delima, Anita Rosa; Zakki, Muhamad
Odonto : Dental Journal Vol 7, No 1 (2020): July 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.7.1.18-24

Abstract

Background: Streptococcus sanguinis is one of the bacteria that plays role in the occurrence of caries, acts as an anchor for the attachment of other oral microorganisms that will form dental plaque in the development of caries. The extract of White Pomegranate peel has several compounds such as flavonoids and tannins that have potential as an antibacterial. Objective: To analyze the antibacterial potency of white pomegranate peel extract against Streptococcus sanguinis bacteria. Methods: Using disc diffusion method (Kirby-Bauer) with 7 treatment groups (n=4). Streptococcus sanguinis bacteria is inoculated in agar medium on petri dish, dripped 50 μl to each disc with 100%, 50%, 25%, 12,5%, 6,25% concentration of pomegranate skin extract, and control group. The petri dish is placed in the incubator at 37oC for 24 hours. Each of antibacterial is observed with the presence of inhibition zones around the disc. The analysis uses Kruskal-Wallis and followed by the Mann-Whitney test. Results: There are inhibitory zones for all treatment concentrations, except for concentration of 12.5%, and 6.25%. There is a significant difference in the concentration of pomegranate skin extract towards the growth of Streptococcus sanguinis bacteria. Conclusion: White pomegranate skin extract has antibacterial potency at 25%, 50%, and 100% concentration
CACAO SEED (THEOBROMA CACAO L.) EXTRACT GEL EFFECT ON THE NEUTROFIL NUMBER AFTER TOOTH EXTRACTION Kurniawati, Atik; Saputra, Dwi Riski; Cholid, Zainul; Putra, Hendito K.
Odonto : Dental Journal Vol 7, No 1 (2020): July 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.7.1.60-67

Abstract

TITANIUM MESH APLICATION ON ANTERIOR ALVEOLAR PROCESS AUGMENTATION PROCEDUR : A CASE REPORT Fathurrahman, Helmi; Hudyono, Rikko
Odonto : Dental Journal Vol 7, No 1 (2020): July 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.7.1.68-72

Abstract

Background: Bone reconstruction in a dental implant is a big challenge work, especially in a large defect where there was no anatomic supporting tissue. Nowadays there is no ideal membrane to be considered. In this case, titanium, even though second surgery is needed, seems the best choice as it can maintain its shape under the flap. Titanium may cause a membrane perforation on the mucosa in a thin gingival phenotype case. Purpose: This case report aimed to present a bone reconstruction procedure using 3D titanium membranes for dental implant treatment. Case. A 37 years old male patient came to the clinic with a chief complaint was a defect on his anterior tooth. Intraoral examination revealed an 11 fractured and luxated. Methode and Treatment Result: We used an allograft covered with 3D Titanium mesh after loading a dental implant. At the end of the surgery, a resorbable membrane was applied. Conclusion: It is concluded that 3D Titanium mesh can be an application for anterior bone reconstruction.
DISCLOSING AGENT FROM RED DRAGON FRUIT PEEL AS DENTAL PLAQUE INDICATOR Purbaningtyas, Eky; Yuliani, Fifin; Ananda, Arief Putra; Sari, Rezmelia
Odonto : Dental Journal Vol 7, No 1 (2020): July 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.7.1.31-39

Abstract

Background: Red dragon fruit peel mucoadhesive gel has the potential to dye dental plaque. The colour of a transparent dental plaque can be seen with visualize using dyes (disclosing agent). One of the natural products containing dyestuff betacyanin, namely the peel of the red dragon (Hylocereus polyrhizus). This research aimed to review the peels of red dragon betacyanin (Hylocereus polyrhizus) in the mucoadhesive gel formula as an alternative disclosing agent.Method: Research is done with the manufacture of thick peels of a red dragon extract with the maceration methods. In clinical trials carried out an application red dragon fruit peel mucoadhesive gel 10%, concentration 15 % and Three-Tone Plaque Disclosing Gel. The assessment of plaque was carried out using the O’leary method. Result: The results obtained were analyzed by the t-test method. The mean of plaque index scores with red dragon fruit peel mucoadhesive gel concentrations of 10% (22.08), 15% (26,29) and Three-Tone Plaque Disclosing Gel (66,21; 64,20). The effectiveness of the gel with a concentration of 10% is 33.87%, and 15% concentration is 40.32%. Conclusion: The mucoadhesive gel of red dragon fruit peel has the potential to colour dental plaque.

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