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INDONESIA
Biomedika
Published by Universitas Muhammadiyah Surakarta
ISSN : -     EISSN : -     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
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Articles 399 Documents
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PERBANDINGAN PEMBERIAN BUFFERED PEHAKAIN DENGAN FRESHLY MIXED LIDOKAIN- EPINEFRIN PADA PERSEPSI NYERI KARENA INFILTRASI ANESTESI LOKAL Pramuningtyas, Ratih
Biomedika Vol 4, No 2 (2012): Biomedika Agustus 2012
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v4i2.256

Abstract

Over the last decade, there has been a rise in the number of surgical procedures being perfomed under local anethesia. The infiltration of the local anesthetic is the most painful part of this procedures, and pain associations can develop into avoidance behaviors in future procedures. Several techniques were used to reduce the pain of local anesthetic infiltration. The objective of this study is comparing the effect of Buffered Pehacaine versus freshly mixed lidocaine-epinephrin in reducing the pain of local anesthetic infiltration. Six subject were recruited for this study. Each subject was received 2 kind of treatment. Subject rated pain using Visual Analog Score. Pain score were compared using paired t test. Sixty seven percent (67%) subjects reported that pain of infiltration was lower in Buffered pehacaine than freshly mixed lidocaine-epinephrine. The difference was not statistically significant. There are no significant difference between Buffered Pehacaine versus freshly mixed lidocaine-epinephrin in reducing the pain of local anesthetic infiltrationKeywords : local anesthetic infiltration, lidocaine, pehacaine
PENGARUH MEROKOK TERHADAP FAAL PARU Basuki, Sri Wahyu; Nilawati, Dona Dewi
Biomedika Vol 3, No 2 (2011): Biomedika Agustus 2011
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v3i2.235

Abstract

Indonesia is thethirdlargestcigaretteusersafter Chinaand India,which reached 146.86 million inhabitants. Smoking behavior is engul?  ng all circles, including children. Dangers of smoking are undoubtedly makes a person not a long life. When compared with non smokers, smokers aged on average 10 years shorter and spend millions of dollars. Inhaled cigarette smoke may accelerate the decline in lung physiology caused by changes in the structure and function of the airway or parenchyma (tissue) in the lung. The objective of this study was to determine differences in pulmonary function (Vital Capacity/VC, Forced Vital Capacity/FVC, and Forced Vital Capacity of the ?  rst second/FEV1) in male smokers and non smokers at the Medical Faculty of uhammadiyah University of Surakarta and determine the effect of smoking on pulmonary function. This study used analytical research design with cross sectional approach. The subject of this study was the active student and employee at the Medicine Faculty, Muhammadiyah University of Surakarta. Purposive sampling method was random sampling. The results were tested by statistical tests of independent t-test with SPSS 16.0.The sample size obtained was 40  people consisted of 20 (50%) sample of smokers and 20 (50%) sample of non-smokers. There was not difference VC between male smokers and nonsmokers with p = 0.390. There was difference FVC between male smokers and nonsmokers with p = 0.000. There was difference FEV1 between male smokers and nonsmokers with p = 0.025.This study showed the difference in FVC and FEV1 between male smokers and nonsmokers in the Medicine Faculty, Muhammadiyah University of Surakarta, but VC did not.
UJI EFEK PEMBERIAN EKSTRAK ETANOL 70% BIJI BUAH TERUNG UNGU (SOLANUM MELONGENA L.) TERHADAP KADAR KOLESTEROL HDL SERUM DARAH TIKUS PUTIH JANTAN (RATTUS NORVEGICUS) GALUR WISTAR Fajriyatun, Baiq Nova; Sutrisna, EM; Nirlawati, Dona Dewi
Biomedika Vol 6, No 1 (2014): Biomedika Februari 2014
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v6i1.282

Abstract

Extract of eggplant fruit (Solanum melongena L.) seed is a plant that has anti-hypercholesterolemia effect on the state of dyslipidemia. One of the compounds contained in them are fl avonoids nasunin which can increase levels of HDL cholesterol (high density lipoprotein). HDL cholesterol is considered as a compound have the ability to remove excess cholesterol from the arteries, and therefore called good cholesterol. This study is a laboratory experimental research using pretest and posttest control group. The sample consisted of 25 rats were divided into 5 groups. Group I is a negative control (-), Group II is a positive control (+), group III was treated 1 (dose 1), group IV was treated 2 (dose 2), and V is the treatment group 3 (dose 3). Each group was given a high-cholesterol diet. Negative and positive control group were not given the extract of fruit seed of eggplant, the treatment groups III, IV, and V were given the extract of fruit seed of eggplant with each dose of 20 mg/kg, 40 mg/kg, 80 mg/kg were given for 4 weeks. HDL cholesterol levels will be measured before and after cholesterol diet and calculated each week after giving of the extract. The data obtained tested with statistical tests One-Way Anova. HDL cholesterol positive control group and the treatment group showed signifi cant differences between groups. Treatment groups 1 and 2 levels of HDL cholesterol lower than the positive control group and the treatment group 3. Extract of eggplant fruit seed dose of 80 mg/kg show an increase in HDL cholesterol levels were signifi cantly (p <0.05). The 70% ethanol extract of eggplant fruit seed at a dose of 80 mg/kg can increase HDL cholesterol levels signifi cantly.Keywords : extract of eggplant fruit seed, hypercholesterol, HDL cholesterol
HUBUNGAN SELF DIRECTED LEARNING READINESS DENGAN TINGKAT KECEMASAN MAHASISWA TINGKAT PERTAMA TAHUN 2010-2011 FAKULTAS KEDOKTERAN UNIVERSITAS MUHAMMADIYAH SURAKARTA Triastuti, N. Juni
Biomedika Vol 5, No 1 (2013): Biomedika Februari 2013
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v5i1.273

Abstract

The anxiety level can be infl uence learning achievement. While the self directed learning readiness can be infl uence learning achievement. The purpose of this study was to determine wheter self directed learning readiness have relationship with the anxiety level at the fi rst medical education student of University Muhammadiyah Surakarta. This study involve 49 responden that receive kuisioner about self directed learning readiness and kuisioner of Hamilton Anxiety Scale. With Spearman test, , the result of this study show that Sig value of the psyche anxiety is 0.550, physics anxiety 0.260 and general anxiety 0.079. This value indicate that there are not signifi cant relationship between self directed learning readiness and the anxiety level. Based on study result, we concluded that self directed learning readiness didn?t have signifi cant relation with the anxiety level at the fi rst medical education student of University Muhammadiyah Surakarta.Keywords: self directed learning readiness, the anxiety level.
HUBUNGAN LAMA PEMBERIAN AIR SUSU IBU DENGAN PRESTASI AKADEMIK SISWA KELAS 1 SEKOLAH DASAR AR RISALAH KARTASURA SUKOHARJO Ichsan, Burhannudin; Wibowo, Bayu Hendro; Sidiq, Muhammad Nur
Biomedika Vol 7, No 2 (2015): Biomedika Agustus 2015
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v7i2.1870

Abstract

Air susu ibu (ASI) adalah makanan ideal bayi baru lahir. Allah menyediakan nutrisi terbaik untuk bayibayi dalam bentuk air susu ibu. Bukti-bukti telah mendokumentasikan keuntungan-keuntungan ASI untuk ibu dan bayi. Banyaknya manfaat yang nyata termasuk perkembangan kognitif yang bagus untuk anak belum dapat memotivasi orang tua utamanya ibu untuk menyusui secara optimal bayi-bayi mereka.Tujuan dari penelitian ini untuk menganalisis hubungan antara lama memberi ASI dengan capaian akademik anak pada tahun pertama SDIT Ar Risalah Kartasura Sukoharjo. Tempat penelitian adalah SDIT Ar Risalah Kartasura, Sukoharjo.Penelitian dilakukan pada bulan oktober 2014. Penelitian ini menggunakan rancangan analitik obseravsional dengan pendekatan cross sectional. Populasi penelitian adalah anak usia sekolah dengan ukuran sampel 80. Hasil dari pengukuran dalam bentuk jawaban ibu yang menyatakan berapa bulan, minggu dan hari dalam menyusui anak dan kemudian dikonversi ke dalam ukuran hari. Variabel terikat adalah capaian akademik dalam skala pengukuran numerik. Capaian akademik diukur dengan melihat nilai rapor anak. Hasil dari dua variabel dianalisis menggunakan korelasi spearman dengan SPSS versi 16.0. Hasil menunjukkan korelasi sangat lemah antara lama ASI dengan capaian akademik siswa kelas 1 SDIT Ar Risalah, Kartasura, Sukoharjo yang secara statistik tidak bermakna. Terdapat korelasi yang sangat lemah antara lama pemberian ASI dengan capaian akademik siswa kelas satu SDIT Ar Risalah Kartasura, Sukoharjo yang secara statistik tidak bermakna.Kata Kunci: ASI, lama, capaian akademik
GEJALA KLINIS SEBAGAI PREDIKTOR PADA KARSINOMA SEL BASAL Pramuningtyas, Ratih; Mawardi, Prasetyadi
Biomedika Vol 4, No 1 (2012): Biomedika Februari 2012
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v4i1.261

Abstract

Basal Cell Carcinoma (BCC) incidence is 75% of all skin cancers. BCC rarely causing mortality, but morbidity is high. Clinical diagnostic is the early detection of BCC suspicion, therefore, we required specific criteria that help to establish the clinical diagnosis. The objective of this study was to know the clinical sign as a predictor of basal cell carcinoma. Ten patients with skin tumors who came to dermatovenereological department of Dr. Moewardi hospital were included in this study. Clinical diagnosis using clinical criteria from keratinocyte carcinoma in A Cancer Journal For Clinicians in 2011 (Teleangiectasion, raise border, erythematous with bleeding, pigmentation, translucent appearance, and scarlike appearance) was used as reference of clinical diagnostic criteria. Histopathological examination was performed as a gold standard. All 10 subjects had histopathological finding consistent to BCC. The clinical examination like pigmentation were found in all subjects while teleangiectasia, raise border, erythema with bleeding were found on 9 subject. Translucent appearance was found on 6 subjects. While scarlike appearance was absent in all subjects. The criteria from keratinocyte carcinoma in A Cancer Journal For Clinicians in 2011 can be used to diagnosed BCC clinicallyKeywords : Basal cell carcinoma, Clinical Diagnostic Criteria
AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAN FRAKSI KULIT BATANG BELIMBING WULUH (Averrhoa bilimbi Linn.) TERHADAP BAKTERI Klebsiella pneumoniae DAN Staphylococcus epidermidis BESERTA BIOAUTOGRAFINYA , MSi., Dr. Muhtadi; Ambarwati, Ria; Yuliani, Ratna
Biomedika Vol 4, No 2 (2012): Biomedika Agustus 2012
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v4i2.252

Abstract

Belimbing wuluh (Averrhoa bilimbi Linn.) is a tropical plant that has antibacterial properties. The purpose of this study was to test the antibacterial activity of bark Belimbing wuluh against Klebsiella pneumoniae and Staphylococcus epidermidis and their bioautography. Extraction methods used to research is method maceration with a solvent ethanol 96 %. Fractinations done by method partition liquid-liquid with a separating funnel. Test performed in this research covering identi? cation bacteria, the sensitivity bacteria, antibacterial activity, thin layer chromatography, bioautography. The result of antibacterial activity ethanol extract of disk diffusion method with concentrations 400 ?g/disk, 800 ?g/disk, 1600 ?g/disk is 8±0,5; 10,34±0,58; 12,17±0,76 on Klebsiella pneumoniae, 10,17±0,29; 11±0; 11.5±0 on Staphylococcus epidermidis, n-hexane fraction with concentration 400 ?g/disk, 800 ?g/disk, 1600 ?g/disk is 8,34±0,29; 9,34±0,29; 10,84±0,76 on Klebsialla pneumoniae, 8,5±0,5; 9,34±0,29; 10,67±0,29 on Staphylococcus epidermidis, ethyl acetate fraction with concentration 400 ?g/disk, 800 ?g/disk, 1600 ?g/disk is 9,17±0,29; 10,34±0,29; 11,17±0,29 on Klebsiella pneumoniae and 9,5±0,5; 10,67±0,29; 12,67±1,26 on Staphylococcus epidermidis, ethanol-water fractions with concentration 400 ?g/disk, 800 ?g/ disk, 1600 ?g/disk is 8,17±0,29; 9,17±0,29; 10±0 on Klebsiella pneumoniae, 9±0; 9,67±0,29; 10,34±0,29 on Staphylococcus epidermidis. The TLC show chemical compounds contained in the ethanol extract, n-heksan fraction, ethyl acetate fraction, and ethanol-water fraction is a compound of the saponins, alkaloids, ? avonoids and phenolic. Bioautography showed that ethanol extracts, n-heksan faction, ethyl acetate fraction, and etanol-airfaction Belimbing wuluh (Averrhoa bilimbi Linn.) bark have not antibacterial activity because there is no clear area around on plate TLC.Keywords: Belimbing wuluh (Averrhoa bilimbi Linn.), ethanol extract, fractination, antibacterial, bioautogra? .
PENGARUH PENYULUHAN TERHADAP PENGETAHUAN IBU HAMIL TENTANG ANESTESI UNTUK OPERASI SECTIO CAESAREA DI POSYANDU KELURAHAN PASAR MINGGU Karnina, Resiana
Biomedika Vol 11, No 2 (2019): Biomedika Agustus 2019
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v11i2.7842

Abstract

Anestesi berperan dalam proses persalinan seorang ibu untuk menghilangkan rasa nyeri terutama dalam tindakan operasi sectio caesarea. Banyak ibu hamil merasa khawatir, cemas dan gelisah menanti saat kelahiran tiba. Pemberian informasi dan edukasi berupa penyuluhan kepada ibu hamil tentang tindakan anestesi untuk operasi sectio caesarea penting untuk menciptakan rasa nyaman dan aman pada diri ibu. Jenis penelitian ini adalah penelitian deskriptif kuantitatif dengan rancangan eksperimen intervensi pada subyek penelitian untuk mengetahui hasil perubahan penngetahuan sebelum dan setelah mendapatkan intervensi penyuluhan. Rancangan ini tidak ada kelompok kontrol. Pengumpulan data dilakukan dengan cara memberikan kuesioner yang diberikan sebelum dan setelah penyuluhan. Hasil dari penelitian ini adalah terdapat pengaruh penyuluhan terhadap pengetahuan ibu hamil tentang anestesi untuk operasi sectio caesarea. Perlu menjadikan penyuluhan sebagai kegiatan rutin pada kelas ibu hamil ataupun kunjungan rumah.Kata Kunci: Pretest, Penyuluhan, Posttest, Pengetahuan Ibu Hamil Anesthesia plays a role in relieving pain during the labor process, especially in sectio caesarea. Many pregnant women feel worried and anxious in waiting for birth to arrive. Giving education in the form of counseling to pregnant women about anesthetic for sectio caesarea surgery is important to make pregnant women will be more comfort and feel secured in the surgery process. This type of research is quantitative descriptive research with experimental design by intervening on the research subjects to determine any changes in the pregnant women?s knowledge before and after the counseling intervention. This design has no control group. Data is gathered from the responses of the pregnant women to the questionnaire that were given before and after the counseling. The result of the experiment is a correlation between the counseling and the knowledge of pregnant women about anesthesia for sectio caesarea surgery. It is necessary to make counseling as a routine activity in the class of pregnant women.Keywords: Pretest, Counseling, Posttest, Knowledge of Pregnant Women 
DAYA ANTIBAKTERI EKSTRAK ETANOL DAUN SENGGANI (Melastoma affine D. Don) Kusumowati, Ika Trisharyanti Dian; Melannisa, Rosita; Prasetyawan, Angga
Biomedika Vol 6, No 2 (2014): Biomedika Agustus 2014
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v6i2.278

Abstract

Melastoma affine D. Don had some activities such as anthelmintic, antibacteria, antiinfiammation, antifungal, and antitumor. The aims of this research was determine antibacteria activity of ethanolic extract of Melastoma affine D. Don. The antimicrobial activity was tested by solid dilution method to get Minimum Inhibition Concentration (MIC). The compounds in Melastoma affine D. Don was analyzed by tube test method and Thin Layer Chromatography (TLC) with chloroform : methanol : formic acid (8,5:1,5:0,5) as mobile phase and silica gel GF254 as stationary phase. The result showed ethanolic extract of Melastoma affine D. Don contains alkaloid, polyphenol, fiavonoid, saponin, and essential oil. The MIC of Senggani against Staphylococcus aureus was 2% and 3% against Escherichia coli and the extract could not inhibit Staphylococcus aureus and Escherichia coli multiresistant until concentration 7% extract ethanol.Keywords: Melastoma affine D. Don, Staphylococcus aureus, Escherichia coli
HUBUNGAN GAYA HIDUP DAN POLA MAKAN DENGAN KEJADIAN HIPERTENSI PADA LANSIA DI KELURAHAN SAWANGAN BARU KOTA DEPOK TAHUN 2015 Mahmudah, Solehatul; Maryusman, Taufik; Arini, Firlia Ayu; Malkan, Ibnu
Biomedika Vol 7, No 2 (2015): Biomedika Agustus 2015
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v7i2.1899

Abstract

Lanjut usia (lansia) merupakan seseorang yang mencapai usia > 60 tahun yang rentan mengalami penyakit yang berhubungan dengan proses menua salah satunya hipertensi. Hipertensi merupakan salah satu faktor resiko penyebab terjadinya penyakit kardiovaskuler. Seseorang dikatakan hipertensi jika hasil pengukuran tekanan darah sistolik > 140 mmHg dan diastolik > 90 mmHg. Beberapa faktor resiko diduga memiliki peran dalam terjadinya hipertensi seperti gaya hidup dan pola makan. Penelitian ini bertujuan untuk mengetahui hubungan gaya hidup dan pola makan dengan kejadian hipertensi pada lansia. Penelitian cross sectional ini diikuti oleh 74 responden dengan cara purposive sampling. Hasil penelitian ini mendapatkan proporsi lansia yang mengalami hipertensi sebesar 26,4%. Analisis bivariat menggunakan uji chi-square dan analisis multivariat dengan regresi logistic ganda. Hasil analisis bivariat menunjukkan ada hubungan antara aktivitas fisik (p=0,024 OR=3,596), asupan lemak (p=0,008 OR=4,364), dan asupan natrium (p=0,001 OR=6,103) dengan kejadian hipertensi. Analisis multivariat menunjukkan asupan natrium (OR Exp(B)=4,627) sebagai faktor resiko yang paling berhubungan dengan kejadian hipertensi. Untuk mengurangi kasus hipertensi perlu adanya cara untuk mencegahnya seperti memberikan penyuluhan kepada masyarakat mengenai hipertensi dan bagi penderita penyakit hipertensi untuk selalu mengontrol tekanan darah dan menghindari faktor-faktor yang menyebabkan terjadinya penyakit hipertensi.Kata Kunci: Hipertensi, Gaya Hidup, Pola Makan

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