cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kota denpasar,
Bali
INDONESIA
BALI MEDICAL JOURNAL (BMJ)
Published by Universitas Udayana
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Bali Medical Journal (BMJ), P-ISSN 2089-1180, E-ISSN 2302-2914 is an international and peer-reviewed journal published quarterly in print and online by Sanglah General Hospital in collaboration to Indonesian Physician Forum and Indonesian College of Surgeon, Bali-Indonesia which was founded in 2011. The Journal aims to bridge and integrate the intellectual, methodological, and substantive diversity of medical scholarship, and to encourage a vigorous dialogue between medical scholars and practitioners. The Journal welcomes contributions which promote the exchange of ideas and rational discourse between practicing educators and medical researchers all over the world.
Arjuna Subject : -
Articles 179 Documents
 11   12   13   14   15 
Lactate Clearance: Predictor for Mortality and Therapeutic Response on Severe Sepsis Patient Siregar, Edwin Saleh; Purnama, Andriana; Rudiman, Reno
BALI MEDICAL JOURNAL Vol 5 No 2 (2016)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (361.689 KB)

Abstract

Background: Severe sepsis and septic shock are at high mortality rate. This high mortality persists as important aspect in the term of patient treatment which take account in determining aggressiveness of relevant therapy. Lactate level consideration was considered important among patient under shock, septicemia, post-operative, acute lung injury, and critical condition. Lactate concentration in static blood was widely studied and suggested as prognostic value among severe sepsis and septic shock patient due to the nature of lactate as the result of anaerobic metabolism. Several study documented the use of lactate as prognostic indicator for shock condition. The increase of lactate concentration could be useful as the indicator of inadequate oxygen delivery and the existence of anaerobic metabolism. Lactate clearance investigation is more superior therapeutic target compared with others oxygen derivate variables. Methods: This research is a cohort observational study involving secondary data which was collected from laboratory examination results of study subjects. The research held from August 2015 to December 2015 in Digestive Division, Surgery Department, Hasan Sadikin Hospital. 42 patient involved in this study. Results: Comparative test results revealed significant lactate clearance based on mortality in LCH (6) (p = 0.000) and H (24) (p =0.000) as well. The level of LC H (6) and H (24) seemed lower in died patient compared with life patient. Conclusion: This study concluded that lactate clearance in died patient was lower in comparison with life patient.
PREVALENCE OF JAUNDICE BASED ON LIVER FUNCTION TEST IN WESTERN NEPAL Singh, P.; Khan, S.; Mittal, and R. K.
BALI MEDICAL JOURNAL Volume 2 Number 2, May-August 2013
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.351 KB)

Abstract

Objectives: The aim of this study was to evaluate the Prevalence of Jaundice Based on Liver Function Test in Patients Attending OPD of Nepalgunj Medical College and Teaching Hospital. Materials and Methods: A hospital based study was carried out in Nepalgunj Medical College, Kohalpur, Banke Nepal to determine prevalence of jaundice. A total of 4280 subjects females and males were included in this study. The study took place from February 2012 to January 2013. Liver function tests were performed using serum levels of bilirubin, total protein,  albumin,  serum  glutamate oxaloacetate transaminase  (SGOT),  serum glutamate pyruvate  transaminase  (SGPT), and alkaline phosphatase (ALP) as indicators of liver function .The results obtained from the above investigation were analyzed and expressed as mean ± SD by using Excel 2007. The comparison was done by student t test on no. of variable of each parameter using SPSS version 16. Results: We investigated the prevalence of jaundice in 4280 subjects on the basis of liver function test. Out of 4280 subjects, 152 patients (3.55%) were selectively diagnosed as jaundiced and another 152 healthy individuals have taken as control. The serum concentrations of all the parameters of liver function test in jaundiced patients were significantly higher (p<0.0001) than those of controls except total protein and albumin which was significantly lower in (p<0.0001) experimental group than the control group. Conclusions: Therefore, from the trend of our data, we can conclude that liver dysfunction is a very common feature in the population of western part of Nepal this may be due most of the people are addicted to alcohol consumption. This need to be stopped and continuous surveillance for bilirubin test is very important to diagnose the jaundice.
Chronic Granulomatous Tolosa-Hunt Syndrome (Case Report) Samatra, D. P.; Kesanda, I M. P.; Indrayani, I. A. A.
BALI MEDICAL JOURNAL Vol 5 No 1 (2016)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (436.144 KB)

Abstract

Background: Tolosa-Hunt syndrome is a rare case, characterized by tenderness, persistent around the affected eye and ophthalmoplegia /paresis caused by granulomatous inflammation in the cavernous sinus region, supra orbital or orbital fissure. Although spontaneous remission may occur, even corticosteroid therapy has a very satisfactory effect. However, relapse can occur after remission. We report a case of granulomatous Tolosa-Hunt syndrome in women aged 47 years who suffer from recurrent Tolosa-Hunt syndrome attacks for 4 years on his left eye, there was a significant recovery after receiving steroid therapy. Case: We report A 47 years old with recurrent pain in the left eye since 4 years, pain episode duration of 1-2 weeks, accompanied by double vision when having long or short distance viewing, and when climbing stairs. The patient left eye was protruded with blurred vision and difficulty in distinguishing green color. Left eye examination vision 1/300, green color discromatopsia, normal funduscopic, ptosis, with paresis eye movement toward the superior, inferior, nasal and temporal. C-reactive protein and erythrocyte sedimentation rate were slightly elevated. ANA test was positive. In visual evoked potential, it showed latency elongation of the left face. Head MRI with contrast showed a isointense protrusion on the left cavernous sinus in axial cuts in T1 and T2. Head MRI T1 with contrast on coronal, axial cuts showed the appearance of convex lesions around the left cavernous sinus that enhanced with contrast. Conclusions: The result was clinically and radiographically diagnosed as Tolosa-Hunt Syndrome (THS). Therefore, 10 mg dexamethasone therapy, 4 times a day for 3 days was lowered to three times on day 4, 2 times on the fifth day and one time at day 6. The patient showed clinical improvement. The patient continued 48 mg oral methylprednisolone therapy up to 3 weeks which then gradually decreased and planned head MRI 3 months later.
ANTI-PLASMODIUM FALCIPARUM IN VITRO ACTIVITY OF CALOPHYLLUM BICOLOR EXTRACT: Morphology and Ultra Structure Kaseke, Martha Marie; Hadju, Veny; Karim, Syafruddin; Nurdin, Armyn
BALI MEDICAL JOURNAL Vol 4 No 3 (2015)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (331.546 KB)

Abstract

Background: Anti-malarial resistance of Plasmodium, such as chloroquine becoming a health problem worldwide. This research aims to evaluate the in vitro anti-plasmodium activity of hexane fraction extract of Calophyllum bicolor (C. bicolor) against culture of Plasmodium falciparum (P. falciparum) 3D7 and determine its inhibitor concentration of 50% (IC50); to observe the microscopic changes of P. falciparum after exposed to the hexane fraction of C. bicolor extract and to observe the ultra structure changes of P. falciparum 3D7 after being exposed to hexane fraction of C. bicolor extract. Method: This research applied quasi experimental with post-test only control group design. Anti malarial activity test of hexane fraction of C. bicolor extract towards Plasmodium falciparum 3D7 2% was undertaken over 48 hours with in vitro incubation technique. The level of parasitemia was observed using binocular optical microscope with 1000x magnification by counting the infected erythrocytes with Giemsa color technique. Then it was analyzed to determine the level of inhibitor concentration of 50% (IC50) of the C. bicolor extract. The next step is to observe the changes of parasite’s morphologic and ultra structure after the 24 and 48 hours incubation of the parasite P. falciparum 3D7 with hexane fraction of C. bicolor, IC50. Then, the morphologic change of P. falciparum 3D7 was observed with optical binocular microscopy and the ultra structure changes with Transmission Electron Microscopy (TEM). The changes of morphologic and ultra structure were analyzed qualitatively. Results: The research revealed that hexane fraction of the C. bicolor extract inhibited the growth of the parasite P. falciparum 3D7 with the value of -49.00±2.54, 12.53±3.13, 23.01±1.10, 27.68±4.23, 48.65±18.71, 70.82±4.67, 80.52±6.17% with the hexane extract concentration of 0, 0.001, 0.01, 0.1, 1, 10, 100, and 1000 µg/mL. This research also found that the inhibitor concentration of 50% (IC50) of hexane fraction of C. bicolor extract was 3.94 µg/mL in 10-7 which could change the morphologic and ultra structure of P. falciparum 3D7. There were several changes in morphology of the parasite over 24 hour incubation compared with the control group, i.e. the nucleus of young tropozoid became thicker, darker, and smaller; the skizon were condensate, thicker, darker, karyorrhexis and demolition of membrane. Hexane fraction of C. bicolor extract also changes the ultra structure over 24 hour incubation, i.e. vacuole membrane boundary and hemozoin were unclear. Over 48 hours of incubation the nucleus and cytoplasm bigger than those in the control group. Conclusion: Hexane fraction of the C. bicolor extract showed a strong anti plasmodium activity towards the in vitro culture of P. falciparum 3D7 at the level of (IC50) 3.94 µg/mL. The Hexane fraction of C. bicolor extract could change the morphology and ultra structure of P. falciparum 3D7 in vitro.
Administration of Leptin Increases the Level of Follicle Stimulating Hormone (FSH) and Development of Ovarian Follicles in Postpartum Anestrus of Bali Cattle Pradnyana, Dewi Indira Laksmi; Pemayun, Tjok G. O.; Damriyasa, I Made; Dharmawan, N. S.
BALI MEDICAL JOURNAL Vol 5 No 2 (2016)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (443.922 KB)

Abstract

Background: Leptin is a metabolic signal that plays a role in reproduction through the Hypothalamic-PituitaryOvarian axis. The aim of this study is to determine the effect of leptin on the levels of FSH and development of ovarian follicles of post-partum anestrus in Bali cattle. Method: Postpartum anestrus in Bali cattle were divided into three groups of nine; group 1 (control) was injected with physiological saline, group 2 (treatment I) and group 3 (treatment II) were injected with recombinant o-leptin 100 µg and 200 µg/head respectively. Injection was done twice with an interval of 12 hours. Blood sample was collected via the jugular vein at intervals of 12 hours before the start of treatment until signs of estrus had appeared. Follicle diameter was measured using ultrasonography before treatment and during estrus. Results: The average levels of FSH before treatment for group 1, group 2, and group 3 were 11.3 + 0.36 mIU/ml, 11.6 + 0.40 mIU/ml, and 11.4 + 0.28 mIU/ml respectively. While at the end of the research, the levels of FSH were 11:02 + 0.39 mIU/ml, 13.0 + 0.48 mIU/ml, and 13.47 + 1.05 mIU/ml respectively. Ovarian follicle diameter for group 1, group 2, and group 3 before treatment were 5.10 + 0.41 mm, 5.21 + 0.36 mm, and 5.00 + 0.37 mm respectively. Whereas at the end of the research, the ovarian follicle diameters were 4.92 + 0.40 mm, 8.37 + 0.43 mm, and 8.45 + 0.38 mm respectively. Conclusion: administration of o-leptin in postpartum anestrus of Bali cattle increases the level of FSH and ovarian follicle development.
EFFECT OF CONJUNCTIVA-LIMBUS TRANSPLANTATION WITH FIBRIN GLUE COMPARE TO SUTURE TECHNIQUE ON STABILITY OF THE GRAFT ATTACHMENT IN PTERYGIUM SURGERY Sutyawan, E; Niti, S; Widiana, and R
BALI MEDICAL JOURNAL Volume 2 Number 1, January-April 2013
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (215.823 KB)

Abstract

Objective: Pterygium is a growth that develops on the conjunctiva or mucous membrane covers the white part of eye. It is a benign or noncancerous growth that is often shaped like a wedge. This study aims to assess the efficacy and safety attachment graft on conjunctiva-limbus autograft transplantation using fibrin glue compared with suture technique in pterygium patient. Method: Single-blind randomized clinical trials. The samples were all pterygium patients with grade two or more who underwent pterygium surgery at the eye clinic and central operating theatre Sanglah General Hospital Denpasar, Bali-Indonesia and met the eligibility criteria. Samples were divided into suture and fibrin glue groups based on permutation-block randomization. Mann-Whitney U test and repeated measurement of ANOVA Analyses were performed to determine the different between two treatments. Results: There were no significant differences in the stability of graft’s attachment between the two groups either on the first day, first week and first month despite fibrin glue technique showed lower results in the first week and first month (p = 0.787, p = 0.233, and p = 0.475). The average time it takes the fibrin glue technique 21.80 ± 2:37 minutes, much shorter than 41.67 ± 6.99 min in the suture technique (p = 0.001). Postoperative comfort in the fibrin glue group showed lower scores on the first day, first week and first month compared with the suture group (p = 0.000, p = 0.000 and p = 0.035). During the follow-up period no complications were found. Conclusion: The stability of graft attachment between the fibrin glue and suture technique is not significantly different.  Fibrin glue could be chosen as an alternative method in the conjunctiva-limbus autograft and helpful in shortening the operating time and improve comfort postoperatively.
LAPAROSCOPIC MANAGEMENT OF A LARGE HYDATID CYST OF LIVER (CASE REPORT) Padhy, Biren Prasad; Hota, P. K.
BALI MEDICAL JOURNAL Vol 4 No 3 (2015)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (471.201 KB)

Abstract

Background: Hydatid disease in humans is endemic in sheep rearing regions. However, a worldwide distribution is encountered. This is a parasitic disease caused by Echinococcus granulossus, which is a cestode. Liver is the most affected organ. Surgery is the mainstay of treatment in hydatid cyst of liver. Since the popularization of laparoscopic surgery, hydatid cyst of liver is being treated laparoscopically in few of the centers. Spillage and anaphylactic reactions are the main pitfalls of laparoscopic management of the hydatid cyst of the liver. We present a case of hydatid cyst of liver, which was managed laparoscopically using Palanivelu Hydatid System (PHS) without any spillage or anaphylactic reaction.
The Clinical Features of Penile Cancer Patients at Sanglah General Hospital Bali-Indonesia Kusmawan, E; *, Bowolaksono; Widiana, R
BALI MEDICAL JOURNAL Volume 1, Number 1, January-April 2012
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (233.246 KB)

Abstract

Objectives: To explore clinical characteristics, treatment modalities and outcomes after the follow-up of penile cancer patients. Method: We reviewed penile cancer patients during 8 years, started from April 1993 to March 2001. The data collected through medical record consisted of patient identities, history takings, physical and pathological findings, treatment modalities and their follow-up after  3±4  years Results:  During eight years of study there were 46 patients aged 58+3 years. Out of 46 patients, 33 patients (72%) have history of urogenital infection and 40 patients (87%) with phymosis. With regard to physical examination, 24 patients (52%) presented as stage III (Jackson classification). Pathological findings showed that 100% patients were keratinizing squamous cell carcinoma. Partial penectomy alone was carried out in 21 patients (46%),  total penectomy alone was done in 17 patients (37%), and total penectomy with lymph node dissection was done in 8 patients (17%). During the follow-up, majority of the patients (42) showed no complications or recurrence, only 2 patients showed recurrent tumor and the rest 2 were lost to follow-up. Conclusions: During eight years at Sanglah General Hospital there were 46 penile cancer patients, mean of age was 58±3 years. Predispositioning factors were urogenital infection and phymosis. All of them were keratinizing squamous cell carcinoma. Total or partial penectomy with or without lymph node dissection was carried out with good results.
The Relationship Between Self-Efficacy and Sexual Function in Patients with Type II Diabetes Haddadi, Samira; Mirkohi, Mahdi Ghodrati; Akbari-Kamrani, Mahnaz
BALI MEDICAL JOURNAL Vol 5 No 3 (2016)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (372.08 KB)

Abstract

Background: Diabetes is a common chronic disease that is increasingly observed in almost all countries of the world. The treatment and prevention of diabetes largely depend on patients’ self-efficacy in performing self-care behaviors. Accordingly, the present study was conducted to examine the relationship between self-efficacy and sexual performance in patients with type II diabetes. Methods: In the present correlational study, 200 patients with type II diabetes (based on physicians’ diagnosis) participated. Using convenience sampling method, the samples were selected out of the whole population of diabetic patients who referred to Shahid Bahonar and Rajaei Hospitals in the city of Karaj (Iran). The data were collected through a multi-faceted questionnaire covering demographic characteristics of the participants, the Diabetes Management Self-Efficacy Scale (DMSES), the Female Sexual Function Index (FSFI) and the Male Sexual Function Index (MSFI). Then, the collected data were analyzed through Pearson correlation test, multiple linear regression analysis, independent t-test and ANOVA. Results: The results showed a positive significant relationship between self-efficacy and sexual function (p
SPECIFIC GYRB SEQUENCE OF MYCOBACTERIUM TUBERCULOSIS CLINICAL ISOLATED FROM SPUTUM OF PULMONARY TUBERCULOSIS PATIENTS IN INDONESIA Mertaniasih, Ni Made; Wiqoyah, Nurul; Kusumaningrum, Deby; Soedarsono, S.; Perwitasari, Agnes Dwi Sis; Artama, Wayan Tunas
BALI MEDICAL JOURNAL Vol 3 No 3 (2014)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (790.131 KB)

Abstract

Background: Indonesia have many different geographic areas which could be various on the variant strains of Mycobacterium tuberculosis. The gyrB gene codes GyrB protein as sub unit compound of Gyrase enzyme that functioning in multiplication of bacteria. Detection of gyrB gene could be a marker of active multiplication of viable bacteria in the specimen from patients; and some of the DNA sequence regions were conserved and specific in the strain of Mycobacterium tuberculosis that would be a marker for identification. This research aims to analyze the sequence of gyrB gene of Mycobacterium tuberculosis clinical isolates from sputum of pulmonary TB patients in Indonesia, and determine the specific region. Method: Mycobacterium tuberculosis clinical isolates have been collected from sputum of the patients with pulmonary TB that live in some area in Indonesia. Isolation and identification of Mycobacterium tuberculosis clinical isolates using standard culture method; sequence analysis using PCR-direct sequencing of the part bases region of gyrB. Results: this study revealed that nucleotide sequence on a fragment 764 bases of gyrB gene Mycobacterium tuberculosis strains among clinical isolates almost identically to a wild type strain Mycobacterium tuberculosis H37Rv and subspecies member of Mycobacterium tuberculosis complex (MTBC), with a little difference of SNPs; there are many difference nucleotide sequence with MOTT and Gram positive or negative bacteria, except Corynebacterium diphtheria identically with MTBC. Conclusion: the gyrB sequence in Mycobacterium tuberculosis strains among these clinical isolates from sputum of pulmonary TB patients in Indonesia have the conserved specific DNA region that almost identically with wild type strain H37Rv and MTBC.

Page 13 of 18 | Total Record : 179

 11   12   13   14   15 

Filter by Year

2012 2016


Reset
Filter By Issues
All Issue Vol 5 No 3 (2016) Vol 5 No 2 (2016) Vol 5 No 1 (2016) Vol 4 No 3 (2015) Vol 4 No 2 (2015) Vol 4 No 1 (2015) Vol 3 No 3 (2014) Vol 3 No 2 (2014) Vol 3 No 1 (2014) Vol 2 No 3 (2013): Vol.2, No.3, September-December 2013 Volume 2 Number 2, May-August 2013 Volume 2 Number 1, January-April 2013 Volume 1, Number 3, September-December 2012 Volume 1, Number 2, May-August 2012 Volume 1, Number 1, January-April 2012 More Issue