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Berkala Kedokteran
Published by Universitas Lambung Mangkurat
ISSN : 14120550     EISSN : 25485660     DOI : http://dx.doi.org/10.20527
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Berkala Kedokteran is a journal contains scientific articles from original research and literature review in medical and health scope. It is published twice in a year, on February and September.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 26 Documents
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Search results for , issue "Vol 14, No 1 (2018)" : 26 Documents clear
Characterization and Antioxidant Potential Albumin Protein of Canna striata Fish to Rattus Novergicus Induced by Isoniazid Toxic Dose Indahsari, Noer Kumala
Berkala Kedokteran Vol 14, No 1 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v14i1.4536

Abstract

Abstract: The Canna Striata fish is a potent source of albumin as an antioxidant. Albumin is a protein capable of binding to free radicals in plasma and has 17 disulfide bonds linking sulfur-containing amino acids. The existence of thiol group bonds in albumin extract of Canna Striata fish is possible to bind to diphenylphycril hydrazyl (DPPH), causing the antioxidant capacity of Canna Striata fish extract to be high. The accumulation of free radicals produced by the administration of antituberculosis drugs from the results of isoniazid metabolism can cause hepatic necrosis. So it requires antioxidants that can reduce free radical levels, which in this study was tested in white rats induced with isoniazid and then treated with albumin protein extract Canna Striata fish. This research method is the first experimental method done is the characterization of albumin protein extract Canna Striata fish with temperature 25˚C and 40˚C by Sodium Dodecyl Sulfate Polyacrilamide Gel Electrophoresis (SDS-PAGE). Then the antioxidant level was tested by measuring the levels of Malondialdehyde (MDA) after 2 last week treatment period in 5 groups of white rats are positive control group, negative control group and 3 treatment groups induced Isoniazid toxic dose are 37.8 mg accompanied by giving of albumin protein extract Canna Striata fish with content of 20ml/kg, 40 ml/kg and 60 ml/kg. The result of this study showed that there were ten albumin protein profiles with size 15,41 kDa, 19,74 kDa 28,6 kDa, 38,87 kDa, 46,08 kDa, 72,45 kDa, 94,42 kDa , 120.82 kDa, 142.80 kDa, and 155.97 kDa. Based on One Way ANOVA and Post Hoc Tukey statistic test, it were found that there was the significant influence and differentiation of Malondialdehyde (MDA) level on giving of albumin  protein extract in white rats induced by Isoniazid with p-value 0,002. The most effective decrease in MDA levels is high levels of albumin protein extract of 60 ml/kg. Keywords: Albumin Protein Extract of Canna Striata, Malondialdehyde, Isoniazid
Physical Activity and The Strength of Bone in Menopause Patients in National Sports Hospital in 2017 Waseso, Laras Bani; Supartono, Basuki; Fauziah, Cut
Berkala Kedokteran Vol 14, No 1 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v14i1.4587

Abstract

Abstract: Osteoporosis is three times more likely to happen to menopause patients with low physical activity because it causes the bone mass to decrease. Standard examination for osteoporosis is a bone mass examination or also known as BMD (Bone Mass Densitometry). This research aims to identify the correlation between physical activity and bone strength in menopause patients. This is an observational analytical research which used cross-sectional design. The sample consists of 74 patients from Kemenpora National Hospital in 2017. The data were analyzed by using Chi-square test. The result shows that 37% of low physical activity patients have normal bone strength, 63% of which have osteopenia and 20% of the patients have osteoporosis. Meanwhile, 52% of medium physical activity patients have normal bone strength, 19% of the patients have osteopenia, and 33% of the patients have osteoporosis. 16% of patients with high physical activity have normal bone strength, 18% of the patients have osteopenia, and 47% of the patients have osteoporosis. This research proves that there is a correlation between physical activity and bone strength in menopause patients (p = 0,004). Keywords: Physical Activity, Bone Mass Densitometry, Menopausal Women
The Relationship of Infectious Diseases History and Mother Factors to Under Red Line Among Toddler Musafaah, Musafaah; Fajriannor, Muhammad
Berkala Kedokteran Vol 14, No 1 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v14i1.4549

Abstract

Abstract: Nutrition under the red line is a state of severe nutritional deficiency caused by low consumption of energy and protein from daily food. Sungai Tiung  is the village that has the highest number of children under five with under red line (BGM) from other villages in the working area of Rawat Inap Cempaka Health Center. This study aims to know the relationship of infectious diseases history and mother factors to under red line (BGM) among toddler in Sungai Tiung. This research uses cross-sectional design. The samples are 90 respondents. Sampling used purposive sampling. The independent variables are a history of infectious disease, knowledge, education, and mother care pattern. The dependent variable is under red line (BGM). The instrument in this study used questionaire and Kartu Menuju Sehat (KMS). The result showed that there is a relationship history of infectious diseases  with BGM (p-value = 0.03). The results also showed no relationship of knowledge (p-value = 0.12), education (p-value = 0.75) and mother care pattern (p-value = 0.32) with BGM. There is a relationship history of infectious diseases  with BGM. So that, there should be efforts to prevent infectious diseases in toddler. Keywords : under red line, toddler, infectious diseases
The Influence of Local Wisdom in The Decision Making Process Ermina Istiqomah; Sudjatmiko Setyobudihono; M Azra Inan Abdillah
Berkala Kedokteran Vol 14, No 1 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (264.02 KB) | DOI: 10.20527/jbk.v14i1.4537

Abstract

Abstract: The existence of an authoritative figure is an indivisible part of society living in Indonesia. The high claims of iron tablets in pregnant women were indicated not followed by high consumption of Fe tablets. Motivation was suspected to be a problem in various treatment processes. The aim of this research was to know the level of influence in influencing the decision and also the perception of various influence roles based on the understanding of local wisdom.  Descriptive method was used by using a closed questionnaire to 130 respondents. The results showed that the husband, the parents and the mother-in-law were the individuals who had an influence on the decision of a pregnant woman. The need for permission was the highest factor chosen regarding the participation in the health program. This study provides an overview of the influence of individuals that must be considered in making a health program for pregnant women. Keywords: health program, influence of individual, local wisdom, pregnant mother
The Relationship of Infectious Diseases History and Mother Factors to Under Red Line Among Toddler Musafaah Musafaah; Muhammad Fajriannor
Berkala Kedokteran Vol 14, No 1 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (191.655 KB) | DOI: 10.20527/jbk.v14i1.4549

Abstract

Abstract: Nutrition under the red line is a state of severe nutritional deficiency caused by low consumption of energy and protein from daily food. Sungai Tiung  is the village that has the highest number of children under five with under red line (BGM) from other villages in the working area of Rawat Inap Cempaka Health Center. This study aims to know the relationship of infectious diseases history and mother factors to under red line (BGM) among toddler in Sungai Tiung. This research uses cross-sectional design. The samples are 90 respondents. Sampling used purposive sampling. The independent variables are a history of infectious disease, knowledge, education, and mother care pattern. The dependent variable is under red line (BGM). The instrument in this study used questionaire and Kartu Menuju Sehat (KMS). The result showed that there is a relationship history of infectious diseases  with BGM (p-value = 0.03). The results also showed no relationship of knowledge (p-value = 0.12), education (p-value = 0.75) and mother care pattern (p-value = 0.32) with BGM. There is a relationship history of infectious diseases  with BGM. So that, there should be efforts to prevent infectious diseases in toddler. Keywords : under red line, toddler, infectious diseases
Potency of Purple Yam (Dioscorea alata L) as an Immunomodulatory Agent Sri Nabawiyati Nurul Makiyah; Muhammad Sasmito Djati
Berkala Kedokteran Vol 14, No 1 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (311.734 KB) | DOI: 10.20527/jbk.v14i1.4589

Abstract

Abstract: Purple yam tuber (Dioscorea alata L.) is one of tubers that has not been used optimally. One of the nutrients contained in Dioscorea species is Saponin Steroid. This paper aims to examine the potential of Steroid Saponin in purple yam tuber (Dioscorea alata L.) as an immunomodulatory agent. The method is by reviewing from various literatures. This article found that Steroid Saponin in purple yam tuber (Dioscorea alata L.) had a potency as an immunomodulatory agent. Keywords: Purple yam tuber (Dioscorea alata L), Steroid Saponin, Immunomodulatory
The Increase in Nutritional Status by Fermented Milk Supplement on Elementary School Children from Fisherman's Village in Bantul, Yogyakarta Province of Indonesia Tri Wulandari Kesetyaningsih; Salmah Orbayinah; Lilis Suryani
Berkala Kedokteran Vol 14, No 1 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (252.524 KB) | DOI: 10.20527/jbk.v14i1.4538

Abstract

Abstract: Probiotics drinks, containing Lactobacillus, were rapidly developed because of its benefit to the health. The bacteria reduced the pathogenic microorganism growth such as virus, fungi, and protozoa. The nutritional status is influenced by food intake, immunity and infection. The children of fisherman’s village are included in the insecure nutrition group because of the low social economic status and healthy living behavior. The aim of this research was to know the influence of daily consumption of probiotics in fermented milk to the nutrition status in elementary school children. This research is quasi-experimental with pretest-posttest control group design. Subjects of 95 elementary school children were divided into 2 groups: 62 children as treatment group and 33 children as control group. Determination of nutritional status is based on anthropometry according to CDC 2000 (BMI-age) growth-chart; and the biochemistry parameter consist of the level of serum total protein, albumin, blood urea nitrogen (BUN), urine creatinine and hemoglobin. Determination of serum total protein and BUN were carried out by Microkjeldahl method, hemoglobine by cyanmet hemoglobin method, albumin by dye-binding method, and creatinine level by Jaffe reaction method. The infection status was determined by anamnesis and laboratory examination of feces which was conducted to find the parasite in the stool. Of sixty five ml fermented milk, that contains of 6.5 x 109 Lactobacillus shirota strain, was consumed every day in 37 days. The data was analyzed by Wilcoxon test for nonparametric data and paired T-test for parametric data.  The result shows that after the treatment, it increased the nutritional status athropometrically from underweight to normal (12.9%) and overweight to normal (3.23%). In biochemically, it increased the total protein level from 6,111 to 6,705 mg/dL (p=0,001) and decreased the BUN from 42,709 to 41,127 mg/dL (p=0,004) significantly eventhough it was in normal range. The conclusion is that consuming fermented milk for 37 days in children is proven to enhance the nutritional status both by anthropometric and biochemistry parameter. Keywords: probiotic, nutritional status, Lactobacillus, fermented milk supplement
Influence of Extract Swiftlet Nest (Collocalia Fuciphago) as Antihyperglycemia to Circulating Endothelial Cells in Rat (Rattus novergicus) Induced by Streptozotocin Francisca Diana Alexandra; Satriyandi M; Agnes Frethernety; Triawanti Triawanti
Berkala Kedokteran Vol 14, No 1 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (225.021 KB) | DOI: 10.20527/jbk.v14i1.4528

Abstract

Abstract: Hyperglycemia could increase the oxidative stress by catalyzes the formation of free radical as anion superoxide(O2-). Oxidative stress will effect in endothelial damaged. This study aimed to evaluated the influence of  extract swiftlet nest  (Collocalia fuciphago) to glucose level and  CEC in rat (Rattus novergicus). Rats were classified into 4 groups, there were control group (K) and 3 treatments group (dose 1; 10 and 100 mg / kgBW) The seventh day  after induced by Streptozotozin (i.p),  the rats  had increased  glucose ± 102 – 108 mg/dL, then treated  with the  extract of   Swiftlet  nest for 28  days  by  oral.  The CEC was measured by Hladovec method. The results showed  the blood glucose level were significant differences ( p = 0.035). The number of CEC decrease significantly (p=0,002). In  conclusion  that extract of Swiftlet  nest  can effect  to decrease  glucose level and CEC number in plasma rat (Rattus novergicus) Keywords: Hyperglycemia, Circulating Endothelial Cells, Collocalia fuciphago
The Potential of Candida Biofilm Protein as Bioreceptor for Candidiasis Immunoassay Masfufatun Masfufatun; Loo Haryanto; Harsono Harsono
Berkala Kedokteran Vol 14, No 1 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (293.058 KB) | DOI: 10.20527/jbk.v14i1.4539

Abstract

Abstract: Candidiasis or infection that is caused by Candida has become a new list of the therapeutical problems recently. The difficulties in diagnosing are the main cause of the unsatisfactory results from common therapies and diagnosis methods. This has urged researchers to find alternative ways in candidiasis diagnosis such as serology-based detection using antigen or antibody development. The aim of this study was to evaluate the potential of protein derived from Candida albicans biofilm as bioreceptor on candidiasis immunoassay through Dot Blot method. The research method used descriptive method with the following stages: (1) preparation of Candida albicans biofilm (2) extraction of Candida albicans protein through enzymatic and mechanical methods, (3) determination of protein molecular weight with SDS-PAGE (4) production of polyclonal anti- candida and (5) analysis of protein extract as bioreeceptor on dot blot. Profile of biofilm proteins on SDS-PAGE analysis were shown on molecular weight 27,42; 29,89; 38,10; 44,90; 48,75; 52,92; 55,14; 59,86; 70,56; 87,36; 102,54;115,05; 130,14;143,14;181,53 kD. There were differences in the intensity of dots in the control group (44070) and treatment groups (63170.5). It is noticeable that biofilm protein extract of C. albicans can be used for induction of anti-Candida polyclonal antibody production as the potential candidate of bioreceptor in candidiasis immunoassay. Keywords: SDS-PAGE, polyclonal antibody, immunoassay, dot blot, biofilm
The Effect of Self-Management Education on Distress of Type 2 Diabetes Mellitus Patients in Ulin General Hospital Banjarmasin, South Kalimantan, Indonesia Noor Diani; Maulidya Septiany; Lola Illona Elfani Kausar
Berkala Kedokteran Vol 14, No 1 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (193.165 KB) | DOI: 10.20527/jbk.v14i1.4529

Abstract

Abstract: The purpose of this study was to analyze the effect of diabetes self management education (DSME) on distress of type 2 diabetes melitus patients which is hospitalized in Ulin General Hospital. This Study used Pre-Experiment with One Group Pretest-Posttest Design. The sample size was 32 patients. The results showed that the average of emotional burden before and after DSME was decrease, with difference number 0.325. The result of Distress among healthcare services before and after DSME was increase (0.211). The result of distress due to diabetes management before and after DSME was decrease (0.119). The result of distress interpersonal relationship before and after DSME was up (0,021). The analysis used Wilcox on Sign Rank test with p= 0,135 (p> 0,05) for emotional distress, p = 0,443 (p> 0,05) for Distress healthcare worker, p = 0.656 (p> 0.05) for distress due to diabetes management. P=0,527 (p>0,05) for Distress interpersonal relationship. The conclusion was there is no significant difference of distress level before and after DSME. It is shown that there is no effect of DSME on distress among patients with diabetes mellitus. Keywords: Diabetes Mellitus, Distress, Diabetes Self-Management Education (DSME)

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