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Published by Universitas Lambung Mangkurat

ISSN : 14120550 EISSN : 25485660 DOI : http://dx.doi.org/10.20527

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Berkala Kedokteran is a journal contains scientific articles from original research and literature review in medical and health scope. It is published twice in a year, on February and September.

Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)

Articles 478 Documents

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KORELASI PANJANG LENGAN ATAS DENGAN TINGGI BADAN PADA WANITA SUKU BANJAR Iwan Aflanie; Fitria Amalia; Mashuri Mashuri
Berkala Kedokteran Vol 12, No 1 (2016)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: The role of identification in the field of forensic medicine is the most important thing to the victims who have died. Identification is needed to reveal the identity of the corpse, one is needed to estimate the length of the corpse. The purpose of this research is analyzing the correlation between the length of upper arm with height in Banjarese student of Medical Faculty at Lambung Mangkurat University and to get height estimation formula based on the length of upper arm in Banjarese woman. The research methodology is the observational analytic with the cross sectional approach method. This research uses the purposive sampling method to take subject result with the total sample as many as 52 people. The Pearson test result showed that value p = 0,000 and value r = 0,933 for right upper arm and r = 0,928 for left upper arm, which indicated a very strong correlation between right and left upper arm with height in Banjarese woman. The conclusion from this research is that there is very strong correlation between the length of upper arm with height in Banjarese woman, with height estimation formula TB = 59,829 + 3,010 x PLAkn for right upper arm and TB = 59,618 + 3,020 x PLAkr for left upper arm. Keywords : identification, height estimation, Banjarese woman Abstrak: Peranan identifikasi dalam bidang ilmu kedokteran forensik merupakan hal paling penting pada korban yang telah meninggal. Identifikasi sangat dibutuhkan untuk mengungkapkan identitas mayat, salah satu yang diperlukan yaitu dengan memperkirakan panjang tubuh mayat tersebut. Tujuan penelitian ini yaitu menganalisis korelasi panjang lengan atas dengan tinggi badan pada mahasiswi suku Banjar di Fakultas Kedokteran Universitas Lambung Mangkurat dan untuk mendapatkan formula estimasi tinggi badan berdasarkan panjang lengan atas pada wanita suku Banjar. Metode penelitian ini yaitu observasional analitik dengan metode pendekatan cross sectional. Pengambilan subjek penelitian menggunakan metode purposive sampling dengan jumlah sampel sebanyak 52 orang. Hasil uji Pearson menunjukkan nilai p = 0,000 dan nilai r = 0,933 untuk lengan kanan dan r = 0,928 untuk lengan kiri, yang menunjukkan adanya korelasi yang sangat kuat antara panjang lengan atas kanan dan kiri dengan tinggi badan pada wanita suku Banjar. Kesimpulan dari penelitian ini yaitu terdapat korelasi yang sangat kuat antara panjang lengan atas dengan tinggi badan pada wanita suku Banjar, dengan formula estimasi tinggi badan TB = 59,829 + 3,010 x PLAkn untuk lengan kanan dan TB = 59,618 + 3,020 x PLAkr untuk lengan kiri. Kata-kata kunci : identifikasi, estimasi tinggi badan, wanita suku Banjar

HUBUNGAN ANTARA USIA IBU HAMIL DENGAN KEJADIAN ABORTUS HABITUALIS DI RSUD ULIN BANJARMASIN PERIODE TAHUN 2010-2013 Desy Elisa Kismiliansari; Ihya Ridlo Nizomy; Lia Yulia Budiarti
Berkala Kedokteran Vol 11, No 1 (2015)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Recurrent miscarriage is an abortion that occurs two or more times in a row before 20 weeks of gestation. Mother’s age is a cause of recurrent miscarriage. The aim of this study is to determine the relation between mother’s age and the incidence of recurrent miscarriage on outpatient clinic and delivery room patients at Obstetric and Gynecologic Department of Ulin General Hospital Banjarmasin from 2010 to 2013. This study used analytic observational method with retrospective approach, the mother’s age was divided into <20 years, 20-35 years, >35 years age group, with Chi-square test at 95% confidence level used to analyze the data. The results showed that from 1.266 patients diagnosed with abortion at Ulin General Hospital Banjarmasin, a total of 37 patients were diagnosed with recurrent miscarriage. We found that the number of women who suffered recurrent miscarriage at <20 years of age was 1 (2.70%) patient, at 20-35 years of age were 21 (56.76%) patients, and at >35 years of age were 15 (40.54%) patients. Overall, a total of 16 (43,24%) patients were within the recurrent miscarriage risk factor age group while 21 (56,76%) patients were outside the risk factor age group. There was a statistically significant relation between mother’s age with the incidence of recurrent miscarriage (χ2 = 10,6, P = 0.05). Keywords: recurrent miscarriage incidence, mother’s age, Obstetric and GynecologicDepartment of Ulin General Hospital Banjarmasin

Influence of Extract Swiftlet Nest (Collocalia Fuciphago) as Antihyperglycemia to Circulating Endothelial Cells in Rat (Rattus novergicus) Induced by Streptozotocin Francisca Diana Alexandra; Satriyandi M; Agnes Frethernety; Triawanti Triawanti
Berkala Kedokteran Vol 14, No 1 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Hyperglycemia could increase the oxidative stress by catalyzes the formation of free radical as anion superoxide(O2-). Oxidative stress will effect in endothelial damaged. This study aimed to evaluated the influence of extract swiftlet nest (Collocalia fuciphago) to glucose level and CEC in rat (Rattus novergicus). Rats were classified into 4 groups, there were control group (K) and 3 treatments group (dose 1; 10 and 100 mg / kgBW) The seventh day after induced by Streptozotozin (i.p), the rats had increased glucose ± 102 – 108 mg/dL, then treated with the extract of Swiftlet nest for 28 days by oral. The CEC was measured by Hladovec method. The results showed the blood glucose level were significant differences ( p = 0.035). The number of CEC decrease significantly (p=0,002). In conclusion that extract of Swiftlet nest can effect to decrease glucose level and CEC number in plasma rat (Rattus novergicus) Keywords: Hyperglycemia, Circulating Endothelial Cells, Collocalia fuciphago

Potensi Ekstrak Kelakai (Stenochlaena palustris (Burm.F) Bedd) terhadap Kadar Tumor Necrosis Factor-Alfa (TNF-α) pada Mencit BALB/c yang Diinfeksi Plasmodium berghei ANKA Denny P.N.H. Margono; Eko Suhartono; Heny Arwati
Berkala Kedokteran Vol 12, No 1 (2016)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Malaria remains a major public health problem in most tropical and subtropical countries, including Indonesia. Severe malaria has a high mortality rate despite treatment with effective antimalarial drug. Pro-inflammatory cytokines such as Tumor Necrosis Factor-alfa (TNF-α) is raised in severe malaria. In South Kalimantan, the kelakai (Stenochlaena palustris (Burm.f) Bedd) has few uses for treat fever and infectious diseases. It contains bioactive substances, such as flavonoids, steroids, and alkaloids which have been reported to exert multiple biological effects, including anti-inflammatory action. The aim of this study is to find out the potential of kelakai extract (KE) againts TNF-α level in BALB/c mice infected P. berghei ANKA. The research is true experimental study, Posttest-only with Control Group Design. Teatment groups were devided into 4 groups treated with 10 mg/kg BW, 100 mg/kg BW of KE, and 36,4 mg/kg BW artesunate orally (positive control), 3 hours post infection and when parasitemia reached 15-20%. Negative controls were without KE treatment and P. berghei infection. Treatment were given for four days. Blood was collected 24 hours after the last treatment. Plasma TNF-α level were measured by sandwich ELISA. Data was analyzed by using Kruskal-Wallis Test, confidence rate at 95%. There was a significant different between treatment groups, where p = 0,000 (p < 0,05). KE potential to inhibit TNF-α production in Pb3K100A- group (p = 0,047).Keywords : Malaria, TNF-α, Stenochlaena palustris Abstrak: Malaria masih menjadi masalah kesehatan utama pada sebagian besar negara tropis dan subtropis, termasuk Indonesia. Malaria berat menyebabkan angka kematian yang tinggi meskipun telah mendapat obat anti malaria yang efektif. Sitokin pro-inflamasi seperti TNF-α meningkat pada malaria berat. Di Kalimantan Selatan, tanaman kelakai digunakan untuk mengobati demam dan penyakit infeksi. Kelakai mengandung senyawa-senyawa bioaktif antara lain flavonoid, steroid, dan alkaloid yang dilaporkan banyak memiliki efek biologis, termasuk aktivitas anti-inflamasi. Tujuan penelitian ini adalah untuk mengetahui potensi ekstrak kelakai terhadap kadar TNF-α pada mencit BALB/c yang diinfeksi P. berghei ANKA. Penelitian ini merupakan studi eksperimental murni dengan Posttest-only with Control Group Design. Kelompok perlakuan dibagi menjadi 4 yaitu kelompok yang mendapat ekstrak kelakai per oral 10 mg/kg BB, 100 mg/kg BB, artesunat 36,4 mg/kg BB (kontrol positif) 3 jam setelah infeksi dan pada saat parasitemia mencapai 15-20%. Kontrol negatif tidak mendapat ekstrak kelakai, artesunat, dan infeksi parasit. Perlakuan diberikan selama 4 hari. Sampel darah diambil 24 jam setelah perlakuan terakhir. Kadar TNF-α diukur dengan ELISA metode sandwich. Data dianalisa dengan Uji Kruskal-Wallis, dengan tingkat kepercayaan 95%. Terdapat perbedaan bermakna antar kelompok perlakuan, nilai p = 0,000 (p<0,05). Ekstrak kelakai berpotensi menghambat produksi TNF-α pada kelompok Pb3K100A- (p = 0,047). Kata-kata kunci : Malaria, TNF-α, Stenochlaena palustris

The Influence of Negative Symptoms on the Social Function of People with Schizophrenia in the Community Warih Andan Puspitosari; Soewadi Soewadi; Sumarni Sumarni
Berkala Kedokteran Vol 14, No 2 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: The most People with Schizophrenia (PwS) experience a decline in social function caused by various factors. Clinical symptoms of PwS affect the social function of PwS, especially negative symptoms. The purpose of this study is to analyze the effect of negative symptoms on the social function of people with schizophrenia in the community. This is a cross-sectional study. Subjects of the study were people with schizophrenia aged 18-56 years who will follow Community-Based Rehabilitation activities in 10 areas of puskesmas in Yogyakarta Special Region. The study was conducted in February 2017. The social function and negative symptoms of PwS were measured using a validated measuring instrument. Hypothesis test using Anova test. The subjects of the study were obtained by purposive sampling technique of 100 PwS that fulfilled inclusion and exclusion criteria. Subjects with a PSP score of 0-30 (poor: someone who intensively needs care and social support) of 8 people (8%) had negative PANSS score of 28.50 ± 6.78. Subjects with a score of 31-70 (moderate: someone who occasionally needs care and social support) of 57 people (57%) had negative PANSS of 20.65 ± 8.18. Subjects with a score of 71-100 (mild: someone with mild disturbance, but able to perform individual functions) of 35 subjects (35%) had negative PANSS score of 12.49 ± 5.98. PwS which has a negative value of PANSS is greater, has a worse social function. The results showed that the negative symptoms had an effect on the social function of people with schizophrenia which was statistically significant (p <0.05). Negative symptoms affect the social function of PwS. PwS that has a high negative symptom score, has a worse social function. Keywords: social function, schizophrenia, negative symptoms

Perbandingan Vo2 Maksimal Pada Siswa Dan Siswi Kelas V Sekolah Dasar: Di Desa Tabanio Kecamatan Takisung Kabupaten Tanah Laut Kalimantan Selatan Krisna Augustian Noor; Huldani Huldani; Agung Biworo
Berkala Kedokteran Vol 9, No 1 (2013)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

ABSTRACT: VO2 maximum is maximum volume that can be processed and O2 consumed by the body that delivered from the lungs to the all of human muscles during physical activities or intense activities until fatugue. Maximum consumption of oxygen was calculated in mililitres/minutes/kilos of body weights. VO2max value was influenced not only by physical characteristhic like age, sex, heights, and weights, but also cardiovascular, respiratory, hematology, and oxydative muscle abilities. The study was conducted by measuring VO2max values for boys and girls grade fifth elementary school in Tabanio village in order to compare both them VO2 max value when they have similarities physical activities cause both of them was helping their parents since childern age. The research approached amount cross-sectional method with samples from 23 boys and 14 girls who includes criteria in non-probability purposive sampling technique. How to measure that is using Multistage Fitness Test that is run back and trajectory as far as 20 m. The results was analyzed by chi-square test with the value expected count < 5, so that the test using an alternative test, the Fisher’s test with p = 0.724. P-value > 0,05 indicating there are non significant difference between maximum VO2max values for boys and girls fifth grade elementary school in Tabanio village with average results of VO2max value is 28,38 for boys and 25,83 for girls. Keywords: VO2max, gender, physical activity ABSTRAK: VO2 maks adalah jumlah volume maksimal O2 yang dapat diproses dan dikonsumsioleh tubuh yang dihantarkan dari paru-paru ke otot manusia pada saat melakukan aktivitas fisik maupun kegiatan intensif sampai terjadi kelelahan. Konsumsi Oksigen maksimal ini dinyatakan dalam satuan mililiter/menit/kilogram berat badan. Nilai VO2 maks dipengaruhi karakteristik fisik seperti umur, jenis kelamin, tinggi badan, dan berat badan. Selain itu, nilai VO2 maks juga bergantung pada keadaan kardiovaskular, respirasi, hematologi, dan kemampuan oksidatif otot. Penelitian dilakukan dengan mengukur nilai VO2 maks siswa dan siswi kelas V sekolah Dasar di desa Tabanio dengan tujuan untuk mengetahui perbandingan nilai VO2 maks keduanya dilihat dari aktivitas fisik yang sama karena disana baik laki-laki maupun perempuan membantu pekerjaan orangtuanya sejak kecil. Pendekatan penelitian menggunakan metode cross-sectional dengan jumlah sampel 23 siswa dan 14 siswi yang memenuhi kriteria inklusi dengan menggunakan teknik non-probability purposive sampling. Cara pengukuran memakai Multistage Fitness Test yaitu lari bolak-balik lintasan sejauh 20 m. Data yang dianalisis dengan menggunakan uji chi-square dengan taraf kepercayaan 95 % antara siswa dan siswi terdapat 1 cell dengan nilai expected count < 5, sehingga uji yang dipakai adalah uji alternatifnya, yaitu uji Fisher dengan nilai p = 0,724. Nilai p > 0,05 menunjukkan bahwa tidak terdapat perbedaan bermakna antara nilai VO2 maksimal siswa dan siswi kelas V Sekolah Dasar di desa Tabanio dengan hasil rata-rata nilai VO2 maks 28,38 pada siswa dan 25,83 pada siswi. Kata kunci: VO2 maks, Jenis Kelamin, Aktivitas Fisik

Analysis of Oral Chronic Kidney Disease with Hemodialysis Therapy in South Kalimantan - Indonesia Isnur Hatta; Khairunnisa Amalia Pratami; Maharani Laillyza Apriasari
Berkala Kedokteran Vol 15, No 2 (2019)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Chronic kidney disease (CKD) is a world health problem where the incidence continues to increase, has a poor prognosis and high-level financing. Clinical manifestations of the oral cavity can occur in CKD patients with hemodialysis therapy due to a decrease in the immune system. To analyze the descriptively the clinical manifestations of oral cavity in CKD patients with hemodialysis therapy at RSUD Ulin Banjarmasin South Kalimantan, period January-March 2019. This is a descriptive analysis with a cross sectional study design, based on history and clinical examination of the oral cavity. Data was entered and analyzed using chi square test. Sampling by purposive sampling. there is a relationship between uremic odor and duration of hemodialysis (p = 0.017). There was a relationship between xerostomia and gender (p = 0.035) and there was a relationship between xerostomia and the duration of hemodialysis (p = 0.007). There is a relationship between gingival swelling and age (p = 0.010) and there is a relationship between gingival swelling and diabetes mellitus (p = 0,000). Manifestations found in the oral cavity of CKD patients with hemodialysis therapy are uremic odor, mouthache, xerostomia, mucosal lesions, candidiasis, and gingival swelling. There is a relationship between sex with xerostomia, the relationship between age with gingival swelling, the relationship between the duration of hemodialysis with uremic odor and xerostomia, the association between DM with gingival swelling. Keywords: Chronic Kidney Disease, Clinical Manifestations, Hemodialysis, Oral Cavity

Perbandingan Efektifitas Asetol-Klopidogrel Terhadap Pasien Penderita Stroke Iskemik Akut Sari Dianita Purnama; Pagan Pambudi; Nelly Al Audhah
Berkala Kedokteran Vol 9, No 2 (2013)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v9i2.941

ABSTRACT: Acute ischemic stroke can make patients get neurology problems that show the signs of paralyze in some part of body and suddenly decrease awareness. The prevalence of acute ischemic stroke which high enough and the bad effects cause the preventing of acute ischemic stroke with right medicine becomes important. Acetosal works as an anti-thromboxane which often known as aspiryn. Clopidogrel is kind of thienophiridyn class drugs that works as an anti-platelet for acute ischemic stroke therapy so that can avoid blood cloting happened. This research aims to know if they have different effectivity or not to acute ischemic stroke therapy by acetosal and combine of acetosal-clopidogrel together. The method uses analythic observational with cohort. The research begins by counting the stroke scale use NIHSS (National Institute of Health Stroke Scale) at the first come to hospital, before patient cured by any drugs, and then repeat the NIHSS’s scoring at seventh day after therapy. Research did for four months with sample that gathered 32 people. First, did normality test to data and after the normality have been proven, use unpaired T-test with interval of confidence 95% that shows the result, there’s no significant difference between acetosal and combined acetosal-clopidogrel for acute ischemic stroke. Keywords: acetosal, clopidogrel, acute ischemic stroke, NIHSS ABSTRAK: Stroke iskemik akut dapat mengakibatkan defisit neurologi yang sebagian besar akan menimbulkan gejala kelumpuhan pada bagian tertentu dan atau terjadi penurunan kesadaran secara mendadak. Angka kejadian yang cukup tinggi dan efeknya terhadap penderita membuat pencegahan stroke iskemik akut dengan obat yang tepat sangat diperlukan. Asetosal adalah terapi yang bekerja sebagai antitromboksan yang sering pula dikenal dengan nama aspirin. Klopidogrel merupakan obat oral kelas tienopiridin yang berperan sebagai antiplatelet dalam terapi stroke iskemik akut sehingga mencegah terjadinya gumpalan darah. Penelitian ini bertujuan untuk mengetahui apakah terdapat perbedaan efektivitas pada terapi stroke iskemik akut menggunakan asetosal dan kombinasi asetosal-klopidogrel. Metode yang digunakan bersifat observasional analitik dengan pendekatan cohort. Penelitian dilakukan dengan cara menghitung derajat stroke pasien menggunakan NIHSS (National Institute of Health Stroke Scale) ketika hari pertama dirawat di rumah sakit sebelum mendapat terapi dan hari ketujuh setelah dilakukan terapi. Penelitian dilakukan selama empat bulan dengan jumlah sampel sebanyak 32 orang. Data pertama-tama diuji normalitas distribusinya kemudian setelah terbukti distribusi normal maka dilakukan uji T tidak berpasangan dengan tingkat kepercayaan sebesar 95% yang menunjukan bahwa tidak terdapat perbedaan bermakna pada terapi stroke iskemik akut dengan asetosal dan kombinasi asetosal klopidogrel. Kata-kata kunci: asetosal, klopidogrel, stroke iskemik akut, NIHSS

Ensefalitis Herves Simplex pada Anak Nurul Hidayah; Ruslan Muhyi
Berkala Kedokteran Vol 10, No 2 (2014)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v10i12.968

Abstract: Herpes simplex virus is a cause of encephalitis in human whose high fatality rate. Herpes Simplex Encephalitis (EHS) can occured in all range of ages without sex predilection with case incidence about 1 in 250.000-500.000 populatation/years. About 40% patients hospitalized in coma state. Coma is a very poor prognostic factors, because patients with coma often died or recovered with severe sequelae. Mortality usually occured in first 2 weeks. In children, this disease has an unspesified clinical manifestation therefore in order to diagnose EHS, a strong clinical suspicion is needeed. In a simple way, we can suspect a children with EHS possibility if a child suffer from febrile, seizure (especially focal seizure) dan other focal neurological symptoms such as hemiparesis or disphasia with progrressive lost of consciousness.Key words: encephalitis, herpes simplex, child Abstrak: Virus Herpes simplex adalah penyebab ensefalitis pada manusia yang seringkali berakibat fatal. Ensefalitis herpes simplex dapat menyerang semua umur, tanpa predileksi jenis kelamin. Angka kejadian adalah 1 dalam 250.000-500.000 populasi per tahun. Empat puluh persen pasien datang di rumah sakit dalam keadaan koma. Koma merupakan faktor prognosis yang sangat buruk, pasien yang mengalami koma seringkali meninggal atau sembuh dengan gejala sisa yang berat. Kematian biasanya terjadi dalam 2 minggu pertama. Manifestasi klinis sangat tidak spesifik terutama pada anak dan diagnosis EHS sangat memerlukan kecurigaan klinis yang kuat. Secara praktis, fikirkan kemungkinan EHS bila menjumpai seorang anak dengan demam, kejang terutama kejang fokal dan gejala neurologis fokal lain seperti hemiparesis atau disfasia dengan penurunan kesadaran yang progresif. Kata-kata kunci : ensefalitis, herpes simplex, anak Ensefalitis Herves Simplex pada Anak

PERBANDINGAN EFEKTIVITAS ANTIFUNGI ANTARA EKSTRAK METANOL KULIT BATANG KASTURI DENGAN KETOKONAZOL 2% TERHADAP Candida albicans IN VITRO Muhammad Baihaqi Siddik; Lia Yulia Budiarti; Edyson Edyson
Berkala Kedokteran Vol 12, No 2 (2016)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Candida albicans is the most common cause of candidacies. Ketoconazole is one of the main options treatment of candidiasis, but is reported to have experienced resistance and hepatotoxic. Extract methanol bark of kasturi contains the same active substance with, Mango that is phenolic groups, terpenoids, and saponins that are antifungal. The purpose of this study was to determine differences in the concentration of the methanol extract of the bark of kasturi with ketoconazole 2% against Candida albicans in vitro. This study was true laboratory experimental by using randomize post test-only group designs, which consisted of 9 treatments, ie EMKBK concentration of 25%, 50% to 37.5%, 62.5%, 75%, 87.5%, 100%, ketoconazole 2% and 70% methanol (control) repetition 3 times with diffusion test. Data analysis using ANOVA and post hoc LSD test (α = 0.05). The result showed mean inhibition zone the methanol extract of the bark of kasturi against Candida albicans at a concentration of 25%, 37.5%, 50%, 62.5%, 75%, 87.5% and 100% is 7 mm; 9 mm; 10 mm; 12 mm; 16 mm; 19 mm, 22 mm and ketoconazole 2% is 15 mm and there is a significant difference between the treatment EMKBK with ketoconazole 2%. Keywords: antifungal, extract methanol bark of kasturi, ketokonazole 2%, Candida albicans Abstrak: Candida albicans merupakan penyebab tersering kandidiasis. Ketokonazol merupakan salah satu pilihan utama untuk mengobati kandidiasis, tetapi dilaporkan telah mengalami resistensi dan bersifat hepatotoksik. Ekstrak metanol kulit batang kasturi mengandung zat aktif yang sama dengan mangga yaitu golongan fenolik, terpenoid, dan saponin yang merupakan antifungi. Tujuan penelitian ini untuk mengetahui perbedaan konsentrasi ekstrak metanol kulit batang kasturi dengan ketokonazol 2% terhadap Candida albicans In Vitro. Penelitian ini adalah eksperimental laboratoris murni dengan mengunakan randomize post test- only group designs , yang terdiri dari 9 perlakuan, yaitu EMKBK konsentrasi 25 %, 37,5 % 50 %, 62,5 %, 75 %, 87,5 %, 100 %, ketokonazol 2% dan metanol 70% (kontrol) pengulangan 3 kali dengan uji difusi. Analisis data mengunakan uji ANOVA dan uji post hoc LSD (α=0,05). Hasil penelitian didapatkan rerata zona hambat ekstrak metanol kulit batang kasturi terhadap Candida albicans pada konsentrasi 25%, 37,5%, 50%, 62,5%, 75%, 87,5% dan 100% adalah 7 mm; 9 mm; 10 mm; 12 mm;16 mm; 19 mm, 22 mm dan ketokonazol 2% adalah 15 mm dan terdapat perbedaan bermakna antara perlakuan EMKBK dengan ketokonazol 2%. Kata – kata kunci: antifungi, ekstrak metanol kulit batang kasturi, ketokonazol 2%, Candida albicans

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