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Dental Journal (Majalah Kedokteran Gigi)
Published by Universitas Airlangga
ISSN : 19783728     EISSN : 24429740     DOI : -
Core Subject : Health,
Dentistry
The Dental Journal (Majalah Kedokteran Gigi) (e-ISSN:2442-9740; p-ISSN:1978-3728) is published by the Faculty of Dental Medicine, Universitas Airlangga. Its diciplinary focus is dental science and dental hygiene. The Dental Journal (Majalah Kedokteran Gigi) is published in English on a quarterly basis with each 50-60 page edition containing between nine and eleven scientific articles on research, study literature and case studies. Contributors to the Dental Journal (Majalah Kedokteran Gigi) included: dental researchers, dental practitioners, lecturers, and students drawn from Indonesia and a wide range of other countries.
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Articles 12 Documents
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Search results for , issue "Vol. 56 No. 4 (2023): December" : 12 Documents clear
Mobe leaf (Artocarpus lakoocha Buch. Ham) ethanol extract's antibacterial activity on Streptococcus mutans cell membrane leakage and biofilm formation: An in vitro study Bahirrah, Siti; Satria, Denny; Yuwanda, Cindy
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 4 (2023): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i4.p226-232

Abstract

Background: Using fixed orthodontic appliances inhibits oral hygiene, which can lead to the increased development of biofilms and Streptococcus mutans, a cariogenic bacterium that is well known for causing dental caries, derived from bacteria of the Streptococcus genus. In order to decrease biofilm and the degree of cariogenic bacteria in the oral cavity, a variety of herbal ingredients are used. Among these, mobe (Artocarpus lakoocha Buch. Ham) leaves are herbal ingredients with antibacterial properties. Purpose: This study aimed to investigate the antibacterial activity, antibiofilm, and leakage of DNA and protein from mobe leaves. Methods: The diffusion method was used to assess antibacterial activity and determine the minimum inhibitory concentration. The antibiofilm activity was evaluated with Ultraviolet–visible (UV-Vis) spectrophotometry (600 nm), using violet crystal staining. The detection of DNA and protein leakage was carried out by checking for absorbance values using the UV-Vis spectrophotometry (260 nm and 280 nm). An increase in the absorbance value in the measured cell indicated an increase in the level of cell content produced by the cell. One-way analysis of variance was used statistically analyze the results of this study (P < 0.05). Results: Mobe leaf (A. lakoocha) extract's minimum inhibitory concentration level was 3.125 mg/ml, the effective concentration of ethanol extract for inhibiting biofilm formation was 3.125 mg/ml, and the effective concentration of ethanol extract that could cause DNA and protein leakage was 50 mg/ml. Conclusions: Mobe leaf extract has good MIC for S. mutans.
Induced pluripotent stem cells in periodontal reconstructive therapy: A narrative review of pre-clinical studies Hendrawan, Reza Dony; Prahasanti, Chiquita; Savitri, Irma Josefina; Hari, Padmini
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 4 (2023): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i4.p280-286

Abstract

Background: Regenerative periodontal surgical therapy faces significant challenges due to the limited ability of the body to regenerate damaged periodontal tissue. One of the primary goals in regenerative periodontal therapy is regaining periodontal tissue attachment after destruction by periodontal disease. Currently, stem cells, harnessing three pivotal components”cells, biomaterials, and growth factors”are widely used in periodontal regeneration. Stem cells can be obtained from various sources, either by isolating cells from bone marrow, teeth, and muscles or through the somatic cell programming method (reprogramming) known as induced pluripotent stem cells (iPSCs). Purpose: This review aims to describe the potential use of iPSCs in the treatment of periodontal defects. Review: Search strategies were developed using the PubMed, LILACS, Scielo, and Wiley online databases during the period of 2012–2022. Ten articles met the inclusion criteria. iPSCs were obtained by inducing somatic cells from both dental and non-dental sources with factors Oct3/4, Sox2, Klf4, and c-Myc. Periodontal tissue regeneration procedures can be augmented with iPSCs. Unlike tooth-based stem cells, iPSCs offer several advantages, such as unlimited cell sources and the capability to differentiate into any cell type, including periodontal tissue. The potential of iPSCs extends to correcting periodontal bone defects and forming new periodontal tissues, such as alveolar bone, cementum, and periodontal ligament. However, iPSCs do have limitations, including the need for clinical trials, cell programming production facilities, and optimization of differentiated-cell functionality. Conclusion: The combined use of iPSCs in cell-based tissue engineering holds vast potential for future periodontal treatment strategies.
Treatment of skeletal Class II with retrognathic mandible in growing patient using modified sagittal guidance twin-block appliance Lubis, Hilda Fitria; Yanita, Sherliana
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 4 (2023): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i4.p261-267

Abstract

Background: Class II discrepancies were primarily perceived as sagittal problems. Class II malocclusions usually cause aesthetic and functional problems, depending on the degree of anterior-posterior mismatch and interaction with adjacent soft tissues. Purpose: This case report aimed to evaluate the effect of modified sagittal guidance twin-block (SGTB) for Class II Skeletal and Dental Changes in a growing patient. Case: A 10-year-old patient presented with her parents and complained mainly of aesthetic problems. Diagnosis showed skeletal Class II pattern (ANB 6º) with retrognathic mandible, angle Class II molar relationship, convex facial profile, lower dental midline shift, crowding in the lower anterior teeth, and incompetent lips. Case Management: A growth modification treatment plan was considered for the patient, using modified SGTB. Both bonded and removable had the same design. In the SGTB, the bite block was angled at 70º, pushed toward the occlusal plane to maximize horizontal force toward the mandible. As a result, the mandible is guided forward and optimally positioned during occlusion. Conclusion: An ideal overjet and slight correction on lower anterior crowding teeth were achieved after full-time wear of a modified SGTB for 12 months. A modified SGTB appliance is effective in treating skeletal Class II with a retrognathic mandible.
Optimization of proteinase K incubation protocol duration during DNA extraction from oral squamous cell carcinoma FFPE samples Meizarini, Asti; Puteri, Astari; Yasan, Yanna Debby Restifanny; Hussaini, Haizal Mohd
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 4 (2023): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i4.p233-237

Abstract

Background: Formalin-fixed paraffin-embedded (FFPE) specimen archives are a valuable source of sample material for molecular biological analysis. However, the DNA isolated from FFPE samples is usually low in concentration and fragmented. Thus, it is necessary to optimize the FFPE DNA extraction protocol to obtain the best results. Proteinase K incubation is undoubtedly crucial in DNA extraction procedures, but this step is often not well explained in the manufacturer's manual. Purpose: This study aimed to find the optimal duration for proteinase K incubation protocols to achieve the highest DNA yields. Methods: Fifteen paraffin blocks of Oral Squamous Cell Carcinoma (OSCC) specimens were obtained, and the cancerous areas were microdissected into smaller cuts for DNA extraction. The samples were randomly divided into three groups (n=5) and subjected to three different proteinase K incubation protocols: one-hour incubation at 56ºC as per the manufacturer's instructions (Group I), 24-hour incubation at 56ºC (Group II), and 48 hours at room temperature with an additional four hours at 56ºC (Group III). The extracted DNA was then quantified using a Nanodrop spectrophotometer. The recorded data were analyzed using ANOVA-LSD. Results: The highest DNA concentration was found in Group III (107.74 ± 41.92), which was significantly higher compared to Group II (59.46 ± 30.32) and Group I (6.46 ± 1.97) (p<0.05). Conclusion: In conclusion, modifying the duration of proteinase K incubation protocols can lead to different DNA yield results. In this study, the most optimized protocol for proteinase K incubation, resulting in the highest DNA yields, was 48 hours at room temperature with an additional four hours at 56ºC.
Relationship between the levels of awareness and knowledge of periodontitis in diabetic patients at a Dental Hospital during the COVID-19 pandemic Nathania, Irene; Harsas, Nadhia Anindhita; Natalina; Tadjoedin, Fatimah Maria
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 4 (2023): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i4.p243-250

Abstract

Background: Diabetes mellitus (DM) and periodontitis are the most prevalent human diseases. Diabetes worsens the periodontal condition, but periodontitis also hampers glycemic control in diabetic patients. Based on staging and grading, the latest periodontitis classification puts DM as one of the grade modifiers. Periodic periodontal maintenance prevents reinfection and could help people with diabetes maintain effective glycemic control. Dental health education and periodontal disease awareness are crucially needed for diabetic patients, especially during the pandemic. Purpose: This study aimed to examine the relationship between levels of awareness and knowledge of periodontitis in diabetic patients during the COVID-19 pandemic. Methods: A closed-ended questionnaire was distributed to new patients referred to the Periodontology Clinic of the Dental Hospital of Universitas Indonesia. Patients' data were collected during the COVID-19 pandemic from January to June 2021. Results: Eighty-four patients participated, of which 34.5 % were diabetic patients with periodontitis. Statistically, significant differences (P < 0.05) were found between levels of awareness and knowledge of periodontitis among diabetic patients and nondiabetic patients (both groups are suffering periodontitis). Awareness and knowledge of periodontitis are inversely correlated with their current clinical periodontal status, therefore patients with less awareness and knowledge have more severe periodontitis. Conclusion: Lack of awareness and knowledge of periodontitis was found among both nondiabetic and diabetic periodontitis patients. Dental health education is required to improve understanding and awareness of the relationship between periodontitis and DM.
The impact of chewing betel nuts on human dentition in Indonesia: A literature review Alaydrus, Sayf Muhammad; Artaria, Myrtati Dyah; Chen, Yao-Fong
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 4 (2023): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i4.p273-279

Abstract

Background: Human behavior can significantly alter dental conditions. One such behavior is the habit of chewing betel nuts. Known as nginang, this tradition holds social significance in many cultures across Indonesia. Societal beliefs include the idea that chewing betel nuts offers a sensation similar to smoking cigarettes, provides a pastime, reduces bad breath, and even enhances dental health. However, evidence shows that it can cause severe damage to teeth. Purpose: This research aims to analyze the literature regarding the impact of chewing betel nuts on dental conditions and to recommend actions to address the problems caused by it. Reviews: While this habit can have positive aspects, it may also cause tooth damage when practiced with a certain frequency and intensity and using specific compositions. Issues such as calculus, periodontitis, attrition, and antemortem tooth loss may occur due to this habit. However, inconsistencies have been found concerning this habit's relation to caries. Conclusion: A pathological chain reaction triggered by betel nut chewing confirms its detrimental effect on dental health. Further investigations are required to explain the inconsistencies found in this review. The researchers recommend promoting tooth brushing to enable society to maintain its tradition without risking further teeth damage.
Pangasius djambal gelatin increases osteoprotegerin, decreases RANK and RANKL after tooth extraction in vivo Mardiyantoro, Fredy; Prasetyaningrum, Nenny; Hidayat, Lukman H.; Khasanah, Uswatun; Roring, Virginia C.; Muizun, Ahida; Kardikadewi, Varellia A. W.
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 4 (2023): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i4.p238-242

Abstract

Background: Osteoprotegerin (OPG) plays a role in preventing osteoclast formation and osteoclastic bone resorption by inhibiting the receptor activator nuclear factor-β and its ligand (RANK–RANKL) interaction that causes bone resorption. Pangasius djambal gelatin contains essential amino acids that may stimulate bone remodeling. Purpose: This study aimed to investigate the expressions of OPG, RANKL, and RANK following tooth extraction to ascertain whether OPG is associated with the RANKL and RANK ratios following gelatin induction. Methods: This study was a true experimental study with a simple, randomized post-test only control group design. Twenty-four albino rats (Rattus norvegicus) were divided into two groups (n = 4). The treatment group was treated with P. djambal gelatin following tooth extraction, while the control group was left untreated. Animal models undergoing tooth extraction were anesthetized intraperitoneally with ketamine (1,000 mg/10 ml up to 0.2 ml). The tooth was then extracted slowly so as not to break it. P. djambal gelatin was dripped (0.1 ml) into the socket after the extraction procedure. The association of OPG with RANKL and RANK immunohistochemistry expressions was evaluated after three, five, and seven days. Results: There was a significant increase in OPG expression on day 7 (P < 0.05) and a significant decrease in the expression of RANKL and RANK (P < 0.05) in the treatment group. Conclusion: The application of P. djambal gelatin could increase OPG expression, decrease RANKL and RANK expression in the socket following tooth extraction, and might be associated with the inhibition of bone resorption.
Comparison outcome of open and close reduction treatments for parasymphysis mandibular fractures Fardhani, Annisa; Rizqiawan, Andra; Mulyawan, Indra; Anugraha, Ganendra
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 4 (2023): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i4.p268-272

Abstract

Background: Mandibular fracture is a condition of mandibular discontinuity. The treatment aims to reconstruct the appropriate anatomical position. Reduction is the process of repositioning fracture fragments to their original anatomical positions, which can be done by open and closed techniques. Open reduction is more invasive, and the possibility of nerve or blood vessel injury and infection postoperatively is greater. Closed reduction also has postoperative complications such as muscle atrophy, periodontal tissue and mucosa damage, speech disorders, and nutritional disorders. In the final determination of the treatment plan, the advantages, disadvantages, and risks of each treatment and the risk of complications should be sufficiently discussed with patients and the patient's guardians. Purpose: This case aims to compare the outcome of open reduction and internal fixation (ORIF) with closed reduction treatment in the management of mandibular parasymphysis fractures. Cases: Two case studies of mandibular parasymphysis fractures. Clinically, each patient had mandibular displacement and occlusion disturbance before treatment. Case Management: The treatment plan is considered by the patient's age and fracture type. One patient received ORIF, and the other received close reduction treatment with gradual repositioning. Malocclusion after treatment was absent in both cases. Conclusion: Open reduction is recommended for displaced parasymphysis fractures. In cases where the open reduction technique cannot be performed, the closed technique can be an alternative, especially on non-displaced or minimally displaced parasymphysis fractures.
Indonesian version of caries management by risk assessment mobile application "SKOR GIGI” in highly educated parents Aluditasari, Alana; Fauziah, Eva; Budiardjo, Sarworini B.
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 4 (2023): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i4.p251-254

Abstract

Background: The Indonesian version of caries management by risk assessment (CAMBRA) is a common caries risk assessment for children aged 0–5 years. During the coronavirus disease 2019 (COVID-19) pandemic, the frequency of dental visits have decreased, making it difficult to assess the caries risk in children. Smartphones and operating systems such as Android are expected to be useful for parents to assess the caries risk of their children. The education level of parents has an impact of its use. The research about the Indonesian version of CAMBRA Android–based application in children aged 0–5 years with highly educated parents has never been done in Indonesia. Purpose: To analyze the accuracy of Android–based application "SKOR GIGI” in assessing the caries risk of children aged 0–5 years by highly educated parents. Methods: This study was conducted in kindergarten, pre-primary school, and Dental Hospital of Faculty of Dentistry Universitas Indonesia with 37 highly educated parents as participants. Participants filled out the informed consent and SKOR GIGI application. Six days later, dentists filled out the Indonesian version of CAMBRA. The results of this study were statistically tested to see the sensitivity, specificity, and the comparison between the variables. Results: The sensitivity test of SKOR GIGI application showed 96.3%, specificity 100%, positive predictive value 100%, and negative predictive value 90.9%. The comparative test with McNemar showed a p-value of 1.000, which means there is no significant difference between the caries risk assessment of children aged 0–5 years using SKOR GIGI application and the Indonesian version of CAMBRA. Conclusion: SKOR GIGI application can be used to assess the caries risk of children aged 0–5 years by highly educated parents.
Analysis of mandibular third molar impaction classification with different skeletal malocclusions Bingül, Muhammet Bahattin; Oğuz, Fırat; Evren, Ayşegül
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 4 (2023): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i4.p213-219

Abstract

Background: Since the third molar teeth are the last to erupt in the oral cavity, they can become more impacted than other teeth. Insufficient retromolar space and the eruption direction of the third molars can affect this situation. The condition, distribution, and prevalence of impacted third molars in skeletal Class I, II, and III anomalies are important in treatment predictability. Purpose: The aim of this study is to classify impacted lower third molars in patients with different skeletal malocclusions. Methods: This retrospective study examined panoramic X-ray records of patients treated at Inonu University Faculty of Dentistry, Department of Orthodontics, between 2014 and 2021. In total, 1219 mandibular third molar teeth were considered. Impacted mandibular third molar teeth of individuals with different skeletal structures were grouped according to the Pell and Gregory, Winter, and Archer classifications. Results: In this study, 37.74% of the participants were male, and 62.26% were female; 40.94% of examined teeth were skeletal Class I, 41.84% were Class II, and 17.23% were Class III. It was determined that 91.63% of all examined teeth were impacted, and 8.37% had erupted. According to the Pell and Gregory classification, 21.41% of teeth were Grade (I), 38.06% were Grade (II), and 40.53% were Grade (III). According to the Winter classification, 3.12% of examined teeth were buccal, 6.89% were horizontal, 23.71% were mesioangular, and 66.28% were vertical. According to the Archer classification, 14.44% of examined teeth were in position A, 30.02% were in position B, and 55.54% were in position C. No statistically significant relationship was established between grades and gender (p>0.05). Conclusion: A relationship was ascertained between the impacted positions of mandibular third molars in different skeletal structures.

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