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Dental Journal (Majalah Kedokteran Gigi)
Published by Universitas Airlangga
ISSN : 19783728     EISSN : 24429740     DOI : -
Core Subject : Health,
Dentistry
The Dental Journal (Majalah Kedokteran Gigi) (e-ISSN:2442-9740; p-ISSN:1978-3728) is published by the Faculty of Dental Medicine, Universitas Airlangga. Its diciplinary focus is dental science and dental hygiene. The Dental Journal (Majalah Kedokteran Gigi) is published in English on a quarterly basis with each 50-60 page edition containing between nine and eleven scientific articles on research, study literature and case studies. Contributors to the Dental Journal (Majalah Kedokteran Gigi) included: dental researchers, dental practitioners, lecturers, and students drawn from Indonesia and a wide range of other countries.
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Articles 964 Documents
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Cleft lip and palate based on birth order and family history at Mitra Sejati General Hospital, Indonesia Hendry Rusdy; Isnandar; Indra Basar Siregar; Veronica
Dental Journal Vol. 55 No. 4 (2022): December 2022
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v55.i4.p221-225

Abstract

Background: Cleft lip and palate is one of the most common congenital abnormalities in infants and is caused by more than one factors, which can be genetic and environmental. Defects in a family gene can result in cleft lip and palate. The study found a high family history relationship with the incidence of cleft lip and palate. Birth order studied by several researchers also has different results, which were influenced by folic acid consumption, maternal knowledge, lack of antenatal care visits and maternal age. To determine the cases of cleft lip and palate based on the birth order of the children and family history of the patients at Mitra Sejati General Hospital. Purpose: The study aimed to investigate cleft lip and cleft palate patients by birth order and family history. Methods: This research was a retrospective descriptive study using survey method. Researchers gave 13 questions through a questionnaire and data were collected and counted manually. Results: The results showed that based on the birth, the cleft case in the first birth order amounted to 25 people, the second 30 people, the third 19 people, and the fourth or more as many as 20 people. Based on family history, 27 patients had a family history of cleft lip and palate, while 67 patients did not have family history. Conclusion: The cases of clefts at Mitra Sejati General Hospital happened more frequently in the second child and most incidence did not have family history.
The effect of herbal medicine in reducing the severity of oral lichen planus: A systematic review and meta-analysis Kharissa Kemala Vychaktami; Rahmi Amtha; Indrayadi Gunardi; Rosnah Binti Zain
Dental Journal Vol. 55 No. 3 (2022): September 2022
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v55.i3.p165-173

Abstract

Background: Oral lichen planus (OLP) is a chronic autoimmune mucocutaneous disease of unknown aetiology. The reported use of herbal medicines may promote the healing of OLP lesions. Purpose: We aim to determine the effectiveness of herbal medicine to reduce the clinical and pain severity of OLP. Methods: PubMed, Cochrane Library and Wiley Online Library were reviewed according to the inclusion criteria. Risk of bias was performed for the randomised control trial (RCT) and cohort studies to assess the effectiveness of herbal medicines for OLP treatment. Outcomes were recorded based on pain severity and the quality of life of patients with OLP. The mean difference and effect size of studies were pooled. Reviews: Out of 1,034 papers, six publications were selected and reviewed. The most common types of OLP lesions were erosive and atrophic and were mainly found at the buccal site. OLP was common in the range of 27–74 years, especially in females. The herbal medicines used in the publication were curcumin, lycopene, purslane, aloe vera and quercetin. Improvement in quality of life or OLP severity was recorded in the intervention group treated with purslane, curcumin and lycopene (P<0.05) but not in the control group. The total effect of herbal medicine in reducing pain severity (measured with the Visual Analogue Scale [VAS]) in OLP patients was not significant (mean difference 0.13; 95% CI -0.202 to 0.463; p=0.442). Conclusions: Herbal medicine cannot be used as a single regime to reduce pain severity. Further research is recommended to evaluate cohort design studies to observe the prolonged effect of herbal medicine in OLP lesions. PROSPERO registration number: CRD42021262282 (2021)
Management of impacted maxillary canine with surgical exposure and alignment by orthodontic treatment Meralda Rossy Syahdinda; Alexander Patera Nugraha; Ari Triwardhani; Tengku Natasha Eleena binti Tengku Ahmad Noor
Dental Journal Vol. 55 No. 4 (2022): December 2022
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v55.i4.p235-239

Abstract

Background: Maxillary canines play a critical point in creating an aesthetic smile as they support the part of facial muscle. Canines are also the second most frequently impacted teeth after the third molars. In some cases, it is possible to retract canines into their correct position by orthodontics treatment. Purpose: This article highlighted a treatment option with surgical exposure, in which a maxillary canine was impacted. It presented gradual steps from pre-surgical to post-surgical orthodontic treatment. Case: A 16 years old female patient referred to Orthodontic Department by Oral Surgeon for pre-surgical orthodontic treatment of her impacted maxillary canine. Case Management: After pre-surgical orthodontic treatment, the impacted canine was surgically exposed by closed technique since open surgical exposure might need excessive removal of the surrounding bone. Traction was given through a gold chain which attached to the palatal surface of the impacted canine. The tooth was ideally positioned with fixed orthodontic appliances. The permanent right maxillary canine was successfully positioned into proper alignment with the remaining teeth. Aesthetic smile was improved. Conclusion: Malocclusion with impacted canine was successfully treated with MBT orthodontic prescription combined with gold chain that can retract the impacted canine into its physiological position and the patient was satisfied with the aesthetic result.
Role of supportive periodontal management in patient with metastatic cancer Kevin Chee Pheng Neo; Nurul Syahirah Mohamad; Avita Rath; Melissa Li Zheng Wong; Myint Wai; Bennete Fernandes
Dental Journal Vol. 55 No. 4 (2022): December 2022
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v55.i4.p231-234

Abstract

Background: Treatment of head and neck cancers may cause sequelae affecting patients’ quality of life during and after treatment. As a result, periodontal management of a patient with parotid gland adenoid cystic carcinoma, particularly in advanced stage 4, can be challenging for dental practitioners, especially if the patient is on active oral molecular therapy and undergoing long-term radiotherapy and chemotherapy. Purpose: This report was intended to describe the conservative non-surgical management of tooth 27 with poor prognosis owing to grade II mobility in a patient on active Lenvatinib therapy – where the extraction was not advisable to lessen the risk of osteonecrosis. Case: A 52-year-old female patient was referred by an oncologist to our dental clinic for noncarious toothache. Five years ago, the patient was diagnosed with adenoid cystic carcinoma (ACC) and had a treatment history of radiotherapy, chemotherapy and surgical removal of the left parotid gland to manage the malignancy. Oral examination revealed characteristic findings of periodontitis. Case Management: Ultrasonic scaling, antimicrobial mouth rinses and reinforcement in oral hygiene instructions manage the tooth 27 conservatively. Conclusion: A cautious approach by the dental surgeon, together with the multidisciplinary team caring for cancer patients, is fundamental and helps with the palliative periodontal management of this patient to enhance oral health-related quality of life. With a lack of reports on conservative periodontal therapy in ACC patients, this report highlights the combination of smoking cessation, reinforcement of oral hygiene instructions and conservative periodontal treatment.
Successful traction of a mesially 90° dilacerated root of impacted maxillary canine: A case report Fani Tuti Handayani; Ida Ayu Evangelina
Dental Journal Vol. 55 No. 4 (2022): December 2022
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v55.i4.p240-245

Abstract

Background: Impacted maxillary anterior teeth are a problem that has a significant impact on the aesthetics of the smile, dental arches, and occlusion. Teeth that have higher tendencies to get impacted are third molars, maxillary central incisors, maxillary canines, and mandibular premolars. Impacted teeth with severe root dilacerations are usually extracted surgically, then the space will be closed by orthodontic treatment or using a prosthesis. Purpose: This study aims to report the successful orthodontic traction of mesially 90° dilacerated root of impacted maxillary canine. Case: A 15-year-old female patient with the chief complaint of an unerupted left maxillary canine. Intraoral examination showed a class I molar relationship on both sides, a unilateral crossbite on the right side, 8 mm spacing between the maxillary left lateral incisor and the premolar. Also, mild crowding was found on both upper and lower anterior segments. CBCT results showed a left maxillary canine was palatally semi-vertical impacted and had a mesially 90° dilacerated root. A significant stress concentration occurred at the middle and apical of the dilacerated root apex when exposed to orthodontic force; this tends to be a higher potential for resorption. Case Management: The impacted dilacerated canine was successfully moved to the proper position by combining crown exposure surgery, orthodontic traction using continuous light force, and gingivectomy. Furthermore, traction was held using a gold chain combined with an elastic thread tied initially to a modified stainless-steel main archwire; this was followed by piggyback tandem wire and a vertical 3/16” light elastic traction. Conclusion: The patient showed successful traction of the canine in less than six months. In addition, the unilateral posterior crossbite was corrected and functional occlusion was achieved. That canine showed good orthodontic and periodontal stability at one-year follow-up, without any evidence of root resorption.
Role of cytotoxic T-lymphocyte antigen 4 (CTLA-4) expression in the pathogenesis of Warthin’s tumor growth Alvionika Nadyah Qotrunnada; Tecky Indriana; Jane Kosasih; Meiske Margaretha; Mei Syafriadi
Dental Journal Vol. 55 No. 4 (2022): December 2022
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v55.i4.p194-199

Abstract

Background: One of the benign salivary gland tumors is Warthin’s tumor, which is a benign tumor consisting of a papillary cystic structure covered by a double epithelial layer cells and lymphoid stroma with germinal center. Several cases have reported the Warthin’s tumor transformation into a malignant tumor such as lymphoma that develops from their stromal. Expression of cytotoxic T-lymphocyte antigen 4 (CTLA-4) as part of the immune checkpoint when highly expressed leads to a more rapid development or progression of tumors. Purpose: To analyze CTLA-4 expression in Warthin’s tumors associated with the pathogenesis of its growth through an escape mechanism from immune checkpoints and analyze based on CTLA expression whether this marker has the potential to be used as immunotherapy by administering anti CTLA-4. Methods: The tissue sections slides of Warthin’s tumor (n=8) were stained with Hematoxylin Eosin and immunostained with Recombinant Anti-CTLA4 antibody [CAL49] (ab237712). The slide with positive CTLA-4 is shown as staining on the cell membrane and/or cytoplasm. Observations were carried out using Optilab. The result is presented as figures. Results: Tumor cells expressed of CTLA-4 show in cytoplasm and/or cell membranes of the epithelial and stromal components of Warthin’s lymphoid. CTLA-4 is expressed lymphoid stroma, which is associated with inhibition of T cell activity against tumor cells, while the exact mechanism of CTLA-4 expression in epithelial components is not known but is thought to induce tumorigenesis and inhibit apoptosis. Conclusion: CTLA-4 is expressed in epithelial and stromal cells of Warthin’s tumor and this expression indicates that Warthin’s tumor cell growth is through the escape mechanism of the CTLA-4 check point immune. Further research is necessary to investigate whether CTLA-4 expression in lymphoid stroma has relate to their transformation toward a malignant tumor of lymphoma.
Labial and palatal alveolar bone changes during maxillary incisor retraction at the Universitas Sumatera Utara Dental Hospital Suci Purnama Sari; Mimi Marina Lubis; Muslim Yusuf
Dental Journal Vol. 55 No. 3 (2022): September 2022
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v55.i3.p148-153

Abstract

Background: The fundamental concept of tooth movement during orthodontic treatment is the occurrence of bone remodelling accompanied by tooth movement in equal proportions. The thickness of the alveolar bone, which supports incisors, is important in estimating the direction of tooth movement. Purpose: The study aimed to measure labial and palatal alveolar bone thickness changes after maxillary incisor retraction using lateral cephalograms. Methods: Cephalograms of 40 patients (18.58 ± 4.2 years) with skeletal Class I bimaxillary protrusion after maxillary first premolar extraction for insisivus retraction had been taken before (T0) and after (T1) orthodontic treatment. Changes in alveolar bone thickness were measured in linear and angular directions and then analysed with Spearman correlative analysis. Then the samples were separated into two groups based on the type of tooth movement (tipping and torque), and then the data were analysed using Wilcoxon analysis to see differences in the bone thickness (p<0.05). Results: There was a significant difference in the apical palate (p<0.05) and a relationship between retraction and alveolar bone thickness in the midroot area. In the angular direction, there was no significant difference and relationship; however, there was a significant difference in the labial crestal in the tipping group. In the torque group, the difference in bone thickness occurred in the crestal and apical palatal areas. Conclusion: The retraction and the type of tooth movement difference influence the alveolar bone thickness.
Oral microbiota in oral cancer patients and healthy individuals: A scoping review Irna Sufiawati; Alamsyah Piliang; Vatchala Rani Ramamoorthy
Dental Journal Vol. 55 No. 4 (2022): December 2022
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v55.i4.p186-193

Abstract

Background: Oral microbiota has been suggested to have a role in the etiopathogenesis of oral cancer; however, the oral microbiota diversity in patients with oral cancer compared to healthy individuals remains unclear. Purpose: This scoping review aimed to provide an overview of the current evidence regarding the oral microbiota composition colonized in oral cancer patients and its comparison with healthy individuals. Reviews: This study was conducted according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. Eligible studies were searched in PubMed, Scopus, Web of Science, and ScienceDirect databases from January 2015 to March 2022. A total of 20 relevant studies were included according to the inclusion and exclusion criteria, including 14 cross-sectional studies and 6 cohort studies. All studies have identified various oral bacteria, but only one study has detected viruses and parasites diversity. A variety of oral microbiota found were 6 phyla of bacteria, 6 phyla of viruses, 7 phyla of fungi, and 7 phyla of parasitic. Seventeen studies proved that oral microbiota compositions were statistically significant differences compared to healthy controls, but not in 3 studies. Conclusion: The majority of studies showed various oral bacteria in oral cancer patients which were statistically significant difference compared to healthy controls. This study indicates the need for more research to evaluate viruses and parasites composition and diversity in oral cancer patients. Moreover, future research should focus to clarify whether the changes of oral microbial composition as a community may play a critical role in the etiopathogenesis of oral cancer.
Creeping attachment post-gingival recession treatment using a vestibular incision subperiosteal tunneling access technique combined with a connective tissue graft Hapsari Kartika Prathivi; Rezmelia Sari
Dental Journal Vol. 56 No. 1 (2023): March 2023
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i1.p13-16

Abstract

Background: The exposed roots of teeth due to gingival recession can generate dentin hypersensitivity and esthetic problems because a patient feels that the teeth, especially the anterior teeth, look long. Recession in thin anterior gingiva often brings unsatisfactory treatment results, so mucogingival surgery, such as vestibular incision subperiosteal tunneling access (VISTA) with the addition of a connective tissue graft (CTG), can be chosen as an appropriate treatment technique. Purpose: This case report describes the creeping attachment phenomenon after treatment of anterior gingival recession with VISTA and CTG techniques. Case: A 28-year-old female patient came with Miller Class I gingival recession in thin anterior gingiva and malposition teeth, complaining about pain and esthetic problems. Case management: The patient was treated with a VISTA technique combined with CTG. The creeping attachment phenomenon seen at three months postoperatively obtained good root coverage so that the patient’s complaints were resolved even though periodic control was needed to evaluate oral hygiene. Conclusion: VISTA and CTG techniques are appropriate for treating anterior mandibular gingival recession with minimal trauma and provide significant results.
Molecular docking study of Zingiber officinale Roscoe compounds as a mumps virus nucleoprotein inhibitor Viol Dhea Kharisma; Santika Lusia Utami; Wahyu Choirur Rizky; Tim Godefridus Antonius Dings; Md Emdad Ullah; Vikash Jakhmola; Alexander Patera Nugraha
Dental Journal Vol. 56 No. 1 (2023): March 2023
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i1.p23-29

Abstract

Background: Mumps virus (MuV) can trigger severe infections, such as parotitis, epididymo-orchitis, and meningitis. The effectiveness of MuV vaccine administration has been proven, but current outbreaks warrant the development of antivirals against MuV. Zingiber officinale var. Roscoe or ginger is often used as an alternative remedy. Currently, there are no known in vitro or in vivo studies that investigate ginger as an MuV antiviral. Purpose: This study aims to evaluate the antiviral potency of the bioactive compounds in Zingiber officinale var. Roscoe against MuV. Methods: Antiviral activity screening was conducted by druglikeness analysis, antiviral probability, molecular docking, and molecular dynamic simulation. Results: As an antiviral, 6-shogaol from Zingiber officinale var. Roscoe has potency against MuV. It has a good binding affinity and can establish interactions with the binding domain of the target protein by forming hydrogen, Van der Waals, and alkyl bonds. Conclusion: The complex of 6-shogaol_NP was predicted to be volatile but stable for triggering inhibitory activity. However, these results must be proved by in vivo and in vitro approaches to strengthen the scientific evidence.

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