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All Journal Journal of Noesantara Islamic Studies Journal of Moeslim Research Technik International Journal of Educatio Elementaria and Psychologia Research Psychologie, Orientation et Conseil Journal of Tecnologia Quantica Techno Agriculturae Studium of Research Journal of Biomedical and Techno Nanomaterials Journal of Humanities Research Sustainability
Luis Santos
University of the Philippines Diliman
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Control & Systems Engineering Education Electrical & Electronics Engineering Engineering Physics Other

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A LAB-ON-A-CHIP DEVICE WITH INTEGRATED GOLD NANOSENSORS FOR THE ULTRASENSITIVE ELECTROCHEMICAL DETECTION OF DENGUE VIRUS BIOMARKERS Andri Setiawan; Luis Santos; Josefa Flores
Journal of Biomedical and Techno Nanomaterials Vol. 2 No. 3 (2025)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v2i3.2479

Abstract

Dengue fever is a significant global health threat, where rapid and accurate diagnosis is crucial for timely clinical intervention and outbreak management. Conventional diagnostic methods are often centralized, time-consuming, and require sophisticated equipment, limiting their utility in point-of-care (POC) settings. This study reports the development and validation of a novel lab-on-a-chip (LoC) device integrating gold nanosensors for the ultrasensitive electrochemical detection of the Dengue virus non-structural protein 1 (NS1). The microfluidic device was fabricated using soft lithography, and the gold electrode surfaces were functionalized with specific anti-NS1 monoclonal antibodies. Detection was performed using differential pulse voltammetry (DPV), measuring the change in current response upon immunocomplex formation. The developed immunosensor exhibited a wide linear dynamic range and an exceptionally low limit of detection (LoD) of 1.5 pg/mL for the NS1 antigen. Furthermore, the device demonstrated high selectivity against other interfering proteins. Our findings successfully establish a robust, miniaturized LoC platform for the rapid and highly sensitive detection of dengue biomarkers. This device holds significant potential as a powerful POC diagnostic tool for the early detection of dengue fever, particularly in resource-limited environments.  
The Role of Subcultures in Defining Urban Identities Rahmat Hidayat; Luis Santos; Maria Clara Reyes
Journal of Humanities Research Sustainability Vol. 1 No. 5 (2024)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jhrs.v1i5.1786

Abstract

identities is often overlooked in urban studies, which place more emphasis on mainstream culture. Purpose. This study aims to identify and analyze how subcultures affect urban identity, especially in the context of social interaction and public policy in the city of Padang.   Method. The research uses a qualitative approach with case studies, involving in-depth interviews and participatory observations. Results. The results show that subcultures have a significant influence in shaping urban identity through cultural expression, social participation, and more inclusive urban policies. Subcultures not only enrich the visual and aesthetic dimensions of cities, but they also play an important role in creating more welcoming and participatory public spaces.   Conclusion. This study concludes that subcultures can be a strategic component in more sustainable and adaptive urban planning, albeit with limitations in scope and research methods that need to be further developed.
Co-Authors Ali Khan Ali Khan Andri Setiawan Dani Lukman Hakim Dara Vann Dito Anurogo Haruto Takahashi Josefa Flores Kaito Tanaka Maria Clara Reyes Nguyen Minh Tu Rahmat Hidayat Raul Gomez Samantha Gonzales Sulaiman Sulaiman Thi Lan Thiago Rocha Vicheka Rith Wahyu Trisno Aji