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All Journal Jurnal Biologi Tropis PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Kesehatan Tambusai JOURNAL LA MEDIHEALTICO MAHESA : Malahayati Health Student Journal Indonesian Journal of Cancer WAL'AFIAT HOSPITAL JOURNAL
Muchsin, Achmad Harun
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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The Relationship of Neoadjuvant Taxanes, Anthracyclines, Cyclophosphamide Chemotherapy on Nutritional Status Based on Body Mass Index (BMI) and Albumin Measurements in Locally Advanced Stage Breast Cancer Patients in Bahteramas Hospital Kendari S Limba, Afirah Khairunnisa; Royani, Ida; Muchsin, Achmad Harun; Kamaluddin, Irna Diyana Kartika; Irsandy, Febie
Indonesian Journal of Cancer Vol 18, No 4 (2024): December
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i4.1283

Abstract

Background: Breast cancer is a disease caused by cancer cells in breast tissue. The most frequently found is locally advanced. The locally advanced stage refers to stages IIIA, IIIB, and IIIC. Neoadjuvant is the treatment for locally advanced. The Taxane, Anthracycline, and Cyclophosphamide (TAC) is a neoadjuvant chemotherapy regimen that can cause nausea and vomiting resulting in decreased appetite and lack of nutritional intake in patients. This study aims to determine the relationship between neoadjuvant TAC chemotherapy and nutritional status based on measurements of BMI and albumin in breast cancer patients at Bahteramas Kendari Hospital.Method: This study was conducted with a retrospective cross-sectional design. The sampling technique was consecutive sampling using 41 medical records of breast cancer patients from the years 2023 to 2024 in Bahteramas Kendari Hospital.Result: There were significant changes in the nutritional status of patients who received neoadjuvant TAC chemotherapy. Before chemotherapy, the patient’s BMI was found to be in the normal category of 34.1% and decreased to 31.7% after chemotherapy. Likewise, patients with obesity were 34.1% before chemotherapy and changed to 19.5% after chemotherapy. Furthermore, there were significant changes in the patient’s albumin levels. Before chemotherapy, 38 patients had normal albumin levels (92.7%), whereas after chemotherapy only 24 patients had normal albumin levels (58.5%).Conclusion: There was a relationship between TAC neoadjuvant chemotherapy and nutritional status based on BMI and Albumin measurements before and after chemotherapy in patients with locally advanced breast cancer.
KARAKTERISTIK LOW BACK PAIN PADA PERAWAT DI RUMAH SAKIT IBNU SINA MAKASSAR Rachman, St Magfira; Royani, Ida; Muchsin, Achmad Harun; Rachman, Moch Erwin; Prasatia Sam, Andi Dhedie
Jurnal Kesehatan Tambusai Vol. 5 No. 4 (2024): DESEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i4.34857

Abstract

Low back pain (LBP) atau nyeri punggung bawah merupakan masalah umum di kalangan tenaga medis khususnya pada perawat. Di Indonesia, prevalensi LBP pada tenaga medis berkisar antara 7,6% dan 37%. Tujuan dari penelitian ini untuk mengetahui karakteristik LBP pada perawat di RS Ibnu Sina Makassar, menggunakan metode deskriptif observasional melalui pendekatan cross-sectional dengan 128 perawat sebagai populasi dan 42 perawat sebagai sampel diambil menggunakan teknik purposive sampling. Variabel yang diteliti mencakup derajat disabilitas, usia, jenis kelamin, masa kerja, lama kerja dan posisi kerja. Instrumen dalam penelitian ini ialah kuesioner ODI (Oswetry Disability  Index) dan REBA melalui observasi dan dokumentasi posisi kerja perawat. Data dianalisis secara univariat untuk menentukan distribusi frekuensi. Hasil penelitian diperoleh perawat yang mengalami LBP terbanyak adalah dengan derajat disabilitas sedang, yaitu 18 orang (42,9%). Sebanyak 21 orang (50,0%) berada dalam rentang usia 26-35 tahun, 36 orang (85,7%) adalah perempuan, 26 orang (66,7%) memiliki masa kerja ?10 tahun, 31 orang (68,9%) bekerja ?8 jam/hari, dan 35 orang (83,3%) berada pada posisi kerja dengan risiko rendah. Sehingga kesimpulan dalam penelitian ini diperoleh kejadian LBP pada perawat di RS Ibnu Sina Makassar paling banyak dengan derajat disabilitas sedang, usia 26-35 tahun, perempuan, masa kerja ?10 tahun, lama kerja ?8 jam/hari, dan posisi kerja level risiko rendah.
LITERATURE REVIEW : PENERAPAN RANGE OF MOTION (ROM) AKTIF CYLINDRICAL GRIP TERHADAP KEKUATAN OTOT PADA PASIEN STROKE Haslinda, Haslinda; Muchsin, Achmad Harun; Akib, Rahmawati
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 2 (2025): AGUSTUS 2025
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v9i2.47662

Abstract

Latihan ROM (Range of Motion) pada penderita stroke merupakan salah satu teknik untuk mengembalikan sistem pergerakan, dan untuk memulihkan kekuatan otot untuk bergerak kembali memenuhi kebutuhan aktivitas sehari-hari. Latihan range of motion (ROM) merupakan bagian dari proses rehabilitasi untuk mencapai tujuan yaitu meningkatkan kekuatan otot. Latihan beberapa kali dalam sehari dan dilakukan pengulangan setiap gerakan agar latihan tersebut dapat optimal di lakukan sehingga dapat mencegah terjadinya komplikasi yang akan menghambat pasien untuk dapat mencapai kemandirian dalam melakukan fungsinya sebagai manusia. Penelitian ini bertujuan untuk mengetahui efektifitas penerapan range of motion cylindrical grip terhadap kekuatan otot pada pasien stroke. Desain penelitian ini adalah Literature Review. Hasil dalam pelaksanaaan penerapan latihan range of motion cylindrical grip dinyatakan mampu meningkatkan kekuatan otot pada pasien stroke yang mengalami kelemahan otot. Dapat disimpulkan bahwa latihan Range Of Motion (Cylindrical Grip) yang dilakukan pada pasien stroke dapat meningkatkan kekuatan otot.
Pengaruh Pemberian Ekstrak Daun Tin Terhadap Kadar Malondialdehyde Pada Tikus Putih Model Stroke Iskemik Salsabilla, Rifdah; Rachman, Mochammad Erwin; Bakhtiar, Ilma Khaerina Amaliyah; Muchsin, Achmad Harun; Utami, Dian Fahmi
MAHESA : Malahayati Health Student Journal Vol 5, No 10 (2025): Volume 5 Nomor 10 (2025)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v5i10.19522

Abstract

ABSTRACT Oxidative stress has an important role in ischemic stroke. Malondialdehyde (MDA) is a biomarker of oxidative stress. A high MDA concentration indicates an oxidation process in the cell membrane. One plant that is thought to contain high levels of antioxidant compounds is fig leaves. Fig leaves contain flavonoid compounds which are an alternative therapy option to prevent the formation of free radicals, thus potentially improving the symptoms of ischemic stroke. The aim of this study was to analyze the effect of administering fig leaf extract (Ficus Carica L.) on MDA levels in white rats (Rattus norvegicus) ischemic stroke model. The purpose of this study was to analyze the effect of tin leaf extract (Ficus Carica L.) on MDA levels in white rats (Rattus norvegicus) ischemic stroke model. This type of research is true experimental which uses Randomized Pretest Posttest Control Group Design using experimental animals. The results showed that there is an effect of giving tin leaf extract (Ficus Carica L.) on MDA levels in white rats (Rattus norvegicus) ischemic stroke model seen in the decrease in MDA levels after being treated with the best dose to reduce MDA levels is 500 mg / kgBB.  Giving this dose can reduce the highest MDA levels on the 7th day after treatment then increase on the 14th day after treatment. The conclusion of this study is giving tin leaf extract (Ficus carica L.) affects MDA levels in white rats (Rattus norvegicus) ischemic stroke model. The optimal dose to reduce MDA levels is 500 mg/kgBB, with the most significant decrease in MDA levels occurring on day 7 after treatment. These results indicate that tin leaf extract has potential as a therapeutic agent in reducing oxidative stress in ischemic stroke conditions, although the effect is temporary. Keywords: Tin Leaf Extract, Malondialdehyde Levels, White Rats, And Ischemic Stroke.  ABSTRAK Stres oksidatif mempunyai peran penting dalam stroke iskemik. Malondialdehyde (MDA) adalah salah satu biomarker stres oksidatif. Konsentrasi MDA yang tinggi menunjukkan adanya proses oksidasi pada membran sel. Salah satu tanaman yang diduga memiliki kandungan senyawa antioksidan yang tinggi adalah daun tin. Daun tin mengandung senyawa  flavonoid yang menjadi salah satu pilihan terapi alternatif untuk mencegah pembentukan radikal bebas sehingga berpotensi memperbaiki gejala stroke iskemik. Tujuan penelitian ini adalah menganalisis pengaruh pemberian ekstrak daun tin (Ficus Carica L.) terhadap kadar MDA pada tikus putih (Rattus norvegicus) model stroke iskemik. Jenis penelitian ini adalah true experimental yang menggunakan rancangan Randomized Pretest Posttest Control Group Design dengan menggunakan hewan coba. Hasil penelitian menunjukkan terdapat pengaruh pemberian pemberian pemberian ekstrak daun tin (Ficus Carica L.) terhadap kadar MDA pada tikus putih (Rattus norvegicus) model stroke iskemik yang terlihat pada penurunan kadar MDA setelah diberi perlakuan dengan dosis yang paling baik untuk menurunkan kadar MDA adalah sebesar 500 mg/kgBB.  Pemberian dosis tersebut dapat menurunkan kadar MDA paling tinggi pada hari ke-7 setelah perlakuan kemudian meningkat pada hari ke-14 setelah perlakuan. Pemberian ekstrak daun tin (Ficus carica L.) berpengaruh terhadap kadar MDA pada tikus putih (Rattus norvegicus) model stroke iskemik. Dosis optimal untuk menurunkan kadar MDA adalah 500 mg/kgBB, dengan penurunan kadar MDA paling signifikan terjadi pada hari ke-7 setelah perlakuan. Hasil ini mengindikasikan bahwa ekstrak daun tin memiliki potensi sebagai agen terapeutik dalam mengurangi stres oksidatif pada kondisi stroke iskemik, meskipun efeknya bersifat sementara. Kata Kunci: Ekstrak Daun Tin, Kadar Malondialdehyde, Tikus Putih, dan Stroke Iskemik
Impact of Muscle Relaxation on Blood Pressure in Primary Hypertension Patients Sudiang Raya Makassar 2024 Herdiansyah, Muh.; Arifin, Arina Fathiyyah; Muchsin, Achmad Harun; Wahyu, Sri; Arfah, Arni Isnaini
Jurnal Biologi Tropis Vol. 24 No. 2 (2024): April - Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i2.6985

Abstract

Hypertension is a serious disease that causes serious complications such as stroke, local myocardial necrosis, cardiovascular disorders, and kidney failure. Hypertension is often nicknamed the "Silent Killer" because it has no side effects. Information from the World Wellbeing Association (WHO) in 2015 shows that this figure will increase to 1.5 billion cases in 2025. The 2018 Fundamental Welfare Exploration (Riskesdas) in Indonesia revealed that the prevalence of hypertension in the population aged over 18 years was 658,201 cases. Moderate muscle relaxation exercises are a non-pharmacological measure that can help lower blood pressure. It is hoped that this examination will determine the relationship between muscle relaxation and reduced blood pressure in essential hypertension patients at the Sudiang Raya Makassar Community Welfare Center. The technique used is One Gathering Pretest-Posttest Plan. Information is dissected using the T test Suitable for evaluating differences in blood pressure during testing. The results of the review showed a significant reduction in systolic and diastolic blood pressure after moderate muscle release treatment, with a p value of 0.000 (p<0.05). Systolic and diastolic blood pressure were reduced by 9.31 mmHg and 4.76 mmHg respectively. There is an effect of mild muscle relaxation treatment on reducing blood pressure in essential hypertension patients at the Sudiang Raya Makassar Community Welfare Center.
Co-Authors Akib, Rahmawati Albaab, Muh. Ulil Ananda, Fadli Arfah, Arni Isnaini Arief, Erwin Arifin, Arina Fathiyyah Bakhtiar, Ilma Khaerina Amaliyah Balqis, Nur Huriyah Gani, Aziz Beru Gayatri, Sri Wahyuni Haslinda Haslinda, Haslinda Herdiansyah, Muh. Ida Royani Irsandy, Febie Isra Yustika, Aulia Jaya, Muh. Alim Jaya, Muhammad Alim Kamaluddin, Irna Diyana Kartika Khairunnisah, Sitti Zhahirah M Azzahra, Mu’awiyah Aulia Makiko, Adrian Mardiana Mardiana Maricar, Fadillah Mochammad Erwin Rachman, Mochammad Erwin Mulyadi, Farah Ekawati Nurmadilla, Nesyana Prasatia Sam, Andi Dhedie Rachman, Erwin Rachman, Moch Erwin Rachman, St Magfira S Limba, Afirah Khairunnisa Salsabilla, Rifdah Shaleh, Humairah Sri Wahyu Surdam, Zulfiyah Tammasesse, Jumraini Utami, Dian Fahmi Wardani, Emy Wiriansya, Edward Pandu Wisudawan, Wisudawan Zhachrani, Noer Fitri Zulfahmidah, Zulfahmidah