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All Journal The International Journal of Tropical Veterinary and Biomedical Research Jurnal Medika Veterinaria
Athaillah, Farida
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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Diagnosis of ehrlichiosis and anaplasmosis in fila brasileiro dog Usrina, Nora; Zulkifli, Baidillah; Hidayat, Farah Amalia; Daniel, Daniel; Nurliana, Nurliana; Roslizawaty, Roslizawaty; Athaillah, Farida; Yusriani, Yenni
The International Journal of Tropical Veterinary and Biomedical Research Vol 10, No 1 (2025): Vol 10 (1) May 2025
Publisher : The Faculty of Veterinary Medicine of Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/ijtvbr.v10i1.45754

Abstract

Background and Aim: Canine ehrlichiosis and anaplasmosis are significant tick-borne diseases with global distribution and high clinical relevance in veterinary medicine. This case report presents a ten-year-old male Fila Brasileiro dog exhibiting clinical signs of anorexia and lethargy for three consecutive days.Materials and Methods: Physical examination revealed fever (40.3 C), pale mucous membranes, and a body condition score of 3/5. A complete blood count (CBC) showed leukocytosis, neutrophilia, eosinophilia, microcytic anemia, and thrombocytopenia. Further confirmation using a SNAP 4Dx rapid test detected antibodies against Ehrlichia spp. and Anaplasma spp., leading to a definitive diagnosis of ehrlichiosis and anaplasmosis. Treatment involved fluid therapy using intravenous 0.9% sodium chloride and doxycycline at a dose of 250 mg per day for 21 days.Results : The hematological findings align with typical abnormalities observed in dogs with these infections, including reduced erythrocyte and platelet counts, which are associated with immune-mediated destruction and bone marrow suppression. These pathogens also alter neutrophil function to evade the host immune response, contributing to prolonged inflammation and disease progression. The hematological profile presented here demonstrates a rare combination of microcytic anemia and eosinophilia, which may suggest an atypical host immune response not commonly described in previous literature.Conclusion: This case highlights the importance of early diagnosis through hematological and serological examinations and emphasizes the need for routine tick prevention to reduce the risk of tick-borne diseases in dogs.
Antidiabetic Test of Ethanolic Extract of Ant Nest Plants (Myrmecodia sp.) Against the -Glucosidase Enzyme In Vitro Daniel, Daniel; Isa, Muhammad; Hasan, Muhammad; Sari, Wahyu Eka; Rosmaidar, Rosmaidar; Aisyah, Siti; Athaillah, Farida; Frengki, Frengki
Jurnal Medika Veterinaria Vol 18, No 1 (2024): J.Med.Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v18i1.37431

Abstract

The use of plants, one of the biological sources, as an alternative medicine for degenerative diseases is increasingly being studied. Usually, the biological effects of these plants come from the secondary metabolite components contained therein. Ant nest is one of them which is reported to contain compounds belonging to the class of flavonoids, tannins, and polyphenols. This research was conducted in vitro by observing the antidiabetic potential of the ethanolic extract of ant nests against the -glucosidase enzyme following the modified "Wako Pure Chemical Industries Ltd., Japan" protocol. The results showed that the inhibitory power of -glucosidase of the extract was stronger than that of the quercetin control with IC50 values of 10.59 g/mL and 38.09 g/mL, respectively. These results proved that the ethanolic extract of ant nest had very strong -glucosidase inhibitory property. Predictive analysis of the pharmacokinetics and toxicity of the bioactive compounds contained in the ant nest extract showed that rutin has similar characteristics to acarbose as a first-line anti-diabetic drug of choice through an -glucosidase inhibitor mechanism, so rutin is worthy of consideration for development as an anti-diabetic candidate.
Egg laying behavior of Aedes aegypti and Aedes albopictus mosquitoes in various containers in Gampong Kopelma Darussalam, Syiah Kuala District Athaillah, Farida; Riandi, Lian Varis; Winaruddin, Winaruddin; Zainuddin, Zainuddin; Usrina, Nora; Putri, Rahmi Eka
The International Journal of Tropical Veterinary and Biomedical Research Vol 9, No 1 (2024): Vol. 9 (1) May 2024
Publisher : The Faculty of Veterinary Medicine of Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/ijtvbr.v9i1.40248

Abstract

This study aims to determine the influence of egg laying behavior on containers on the density of Aedes aegypti and Aedes albopictus mosquito larvae in Gampong Kopelma Darussalam, Syiah Kuala District. Sampling was conducted using a simple random sampling technique by surveying larvae in containers from 100 houses. This was followed by the identification of mosquito larval species, and the data were analyzed using entomological indices and Chi-Square tests. Based on the calculation of the entomological index in Gampong Kopelma Darussalam, Syiah Kuala District obtained the values of the House Index, Container Index, and Breteau Index for containers outside the house are 15%, 28.3%, and 17% and the values of House Index, Container Index and Breteau Index for containers in the house are 26%, 13.1%, and 29% so that it can be categorized that the density of Aedes aegypti and Aedes albopictus mosquito larvae in Gampong Kopelma Darussalam, Syiah Kuala District is moderate. The results showed that Aedes aegypti was found to be more than 85.1% compared to Aedes albopictus 14.9%. The analysis results showed a relationship between the type, location, material, size, and color of the container with the presence of Aedes aegypti mosquito larvae in contrast to Aedes albopictus mosquito larvae which showed a relationship with the type, location, and material of the container. The results indicated that Aedes aegypti mosquito larvae were predominantly found in containers inside the house, whereas Aedes albopictus mosquito larvae were more frequently found in containers outside the house.
Co-Authors Daniel Daniel Frengki Frengki, Frengki Hidayat, Farah Amalia Muhammad Hasan Muhammad Isa Nora Usrina NURLIANA NURLIANA Rahmi Eka Putri, Rahmi Eka Riandi, Lian Varis Roslizawaty Roslizawaty, Roslizawaty Rosmaidar Rosmaidar, Rosmaidar Sari, Wahyu Eka Siti Aisyah Winaruddin Winaruddin Yenni Yusriani Zainuddin, Zainuddin Zulkifli, Baidillah