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All Journal The Indonesian Biomedical Journal Al-Daulah : Jurnal Hukum dan Perundangan Islam Jurnal Nusa Sylva Jurnal Elektronika dan Telekomunikasi Narra J Innovative: Journal Of Social Science Research
Hatta, Mohammad
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Electrical & Electronics Engineering Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Other

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PENGARUH KONSENTRASI PUPUK ORGANIK CAIR (POC) BIOTON TERHADAP PERTUMBUHAN TRUBUSAN JATI UNGGUL NUSANTARA (Tectona grandis sp.) DI KEBUN PERCOBAAN COGREG UNIVERSITAS NUSA BANGSA Putra, Suriya Adi; Satjapradja, Ombo; Hatta, Mohammad
Jurnal Nusa Sylva Vol. 12 No. 2 (2012): JURNAL NUSA SYLVA
Publisher : Universitas Nusa Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (353.896 KB) | DOI: 10.31938/jns.v12i2.138

Abstract

Jati Unggul Nusantara (JUN) can be propagated vegetative using Coppice System, with the addition ofBioton Liquid Organic Fertilizer. This study aimed to determine the effect of concentration on the growth Coppice Systemof JUN useful Bioton Liquid Organic Fertilizer to expectations providing information enrichment Coppice System of JUN regeneration techniques. Required 25 JUN stump and Bioton as an ingredient and requires a machete/knife, phi band, milli meter scrup, measuring ruler (cm), label, beakers, volumetric pipette, water spray, rubber gloves, tally sheets, stationery and computer processing of the data as a tool. Five levels of concentration treatments given in this study is 1). concentration of 0%(0ml /l) as control, 2). concentration of 5%, 3). concentration of 10% (10 ml / l), 4). concentration of 15% and 5). concentration of 20% with five repetitions at each concentration. Sampling was purposive sampling method and analyzed using a randomized block design (RBD). Average maximum height occurs at a concentration of 5 % ( 300.67cm ) , then 20 % ( 290.90 cm ) , 15 % ( 270.90 cm ) 10 % ( 270.30 cm ) and 0 % ( 265.17 cm ) . Coppice maximum height reached by the end of the observation 375cm at concentrations of 5 %, while the minimum height is 170cm trubusan reached at concentrations of 0 %. Average maximum diameter occurs at concentrations of 5 % with the achievements of diameter 4.29 cm, followed by a concentration of 20 % with the achievements of diameter 4.26 cm, the concentration of 15 % with the achievements of 4.16cm diameter, the concentration of 10 % with the achievements of diameter 3.91 cm and average performance the average minimum diameter is 3.87 cm occurred at concentrations of 0 % or control. Reaches a maximum diameter of 5.63 cm were artifacts at concentrations of 5 %, while achieving a minimum diameter of 2.86 cm at a concentration of 10 %, and there were no coppice disease, but there are leaf-eating caterpillar pests.
ETNOBOTANI DAN TUMBUHAN BERGUNA DI CAGAR ALAM DUNGUS IWUL BOGOR Kusharsono, Sony; Panjaitan, Poltak BP; Hatta, Mohammad
Jurnal Nusa Sylva Vol. 13 No. 2 (2013): JURNAL NUSA SYLVA
Publisher : Universitas Nusa Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (322.751 KB) | DOI: 10.31938/jns.v13i2.147

Abstract

People's lives around the Nature Reserve (CA) has a very close interaction with the natural resources around them. One of them is the interaction associated with the use of plants (ethnobotany). Documenting knowledge society CA Dungus Iwul ethnobotany essential to keep the knowledge society CA Dungus Iwul in the utilization of the plant is not lost. This study aims to determine the potential of useful plants in the region CA Dungus Iwul and examine the use of plants by people around CA Dungus Iwul (ethnobotany). Ethnobotany study conducted by interview and to determine the potential of plants useful in the CA Dungus Iwul done with vegetation analysis. The number of plant species that are found from the analysis of the vegetation in the area Dungus Iwul CA acquired as many as 43 species of 25famili. Most useful plant species are as many as 21 species of medicinal plants. While the study of ethnobotany identified as many as 30 species of 21 families and each has been grouped into 11 groups of usefulness, where the species is found mostly serves as a group of as many as 25 species of medicinal plants. Habitus most dominating of the results of the analysis of seedling and plant vegetation is under the most dominating family is Arecaceae, while on the study of ethnobotany is habitus of shrubs with family Zingiberaceae. Based on the percentage of habitat types, the plant most widely used by the public is a plant cultivated 20 species (67%) and 10 species (33%) is a wild plant, which used only a small portion of the area CA Dungus Iwul about 7 species. Their use of plants that originate from within the CA Dungus Iwul indicate that there has been interaction, ie interaction in the form of plant utilization. However, the interaction is still relatively low so that the possibility of damage to a small area.
Computational drug repurposing for tuberculosis by inhibiting Ag85 complex proteins Iskandar, Israini W.; Nurhasanah, Astutiati; Hatta, Mohammad; Hamid, Firdaus; Handayani, Irda; Chaera, Ummi; Yusriyyah, Andi A.; Jamaluddin, Balqis D.; Zaenab, St; Hidayah, Najdah; Karimah, Nihayatul; Permana, Andi D.; Massi, Muhammad N.
Narra J Vol. 5 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i1.1130

Abstract

Tuberculosis (TB) remains a significant and deadly infection among pulmonary diseases caused by Mycobacterium tuberculosis, a highly adaptive bacterium. The ability of M. tuberculosis to evade certain drugs has been linked to its unique structure, particularly in the cell envelope, where the Ag85 complex proteins play an essential role in this part.  The aim of this study was to utilize a drug repurposing strategy targeting the Ag85 complex proteins. This study utilized a computational approach with 120 selected drugs experimentally identified to inhibit Tuberculosis. A virtual screening molecular docking with Autodock Vina was used to filter the compounds and identify the strong binders to the Ag85 Complex. Molecular dynamics simulations employed the Gromacs Packages to evaluate the stability of each complex, including root mean square deviation (RMSD), root mean square fluctuation (RMSF), and radius of gyration (RoG). Additionally, absorption, distribution, metabolism, excretion, and toxicity (ADMET) assessments were conducted to gather more information about the drug-likeness of each hit compound. Three compounds, selamectin, imatinib, and eltrombopag were selected as potential drugs repurposed to inhibit the activity of the Ag85 complex enzyme, with binding affinities ranging between -10.560 kcal/mol and -11.422 kcal/mol. The MD simulation within 100 ns (3 replicas) showed that the average RMSD of each Ag85A complex was 0.15 nm–0.16 nm, RMSF was 0.09 nm–0.10 nm, and RoG was 1.80 nm–1.81 nm. For Ag85B, the average RMSD was 1.79 nm–1.80 nm, RMSF was 0.08 nm–0.09 nm, and RoG was 1.79 nm – 1.80 nm. Then, for Ag85C, the mean RMSD was 0.16 nm–0.18 nm, RMSF was 0.09, and RoG was 1.77 nm. The study highlights that these promising results demonstrate the potential of some repurposed drugs in combating the Ag85 complex.
MLC 901 Decreases HSP-70, MMP-9, Cerebral Infarction Volume and Functional Outcome in Acute Ischemic Stroke Rat Model Hunaifi, Ilsa; Bintang, Andi Kurnia; Tammasse, Jumraini; Wahid, Isra'; Hatta, Mohammad; Islam, Andi Asadul; Zainuddin, Andi Alfian; Sugianto, Paulus
The Indonesian Biomedical Journal Vol 17, No 3 (2025)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v17i3.3610

Abstract

BACKGROUND: Acute ischemic stroke (AIS) is usually treated with thrombolysis, however the percentage of patients receiving this therapy is not quite low. Therefore, it is necessary to find alternative therapy using neuroprotective agent such as Moleac (MLC) 901. Heat shock proteins (HSP)-70 and matrix metalloproteinase (MMP)-9 are usually related to AIS due to the triggered stroke-induced physiological stress. However, the effect of MLC 901 on Hsp70 mRNA expression, HSP-70 and MMP-9 remains unclear. This study was conducted to determine the effect of MLC 901 on those three parameters in relation to cerebral infarction volume and functional outcomes in an AIS model.METHODS: Rats were induced with AIS using unilateral common carotid artery occlusion (UCAO) and received three different treatments: 43.2 mg/200 gBW MLC 901, 21.6 mg/200 gBW MLC 901, and sodium carboxymethyl cellulose (CMC-Na), that were administered orally for 14 days. HSP-70 and MMP-9 protein levels were assessed using enzyme-linked immunosorbent assay (ELISA), and Hsp70 mRNA expression was assessed using quantitative real-time polymerase chain reaction (qRT-PCR). Foot fault scores for evaluation functional outcome and infarction volume were assessed by ImageJ.RESULTS: AIS-induction increased HSP-70, MMP-9, and Hsp70 mRNA expression within 24-48 h. MMP-9, HSP-70 , and Hsp70 mRNA expression were reduced by MLC 901. MLC 901 at dose of 43.2 mg/200 gBW and 21.6 mg/200 gBW were effective in reducing these levels compared to the control. MLC 901 improved functional outcomes and decreased cerebral infarction volume. Moreover, a dosage of 43.2 mg/200 gBW was more effective in reducing Hsp70 mRNA expression and HSP-70, improving functional outcomes, and reducing cerebral infarction volume than a dosage of 21.6 mg/200 gBW, but not MMP-9 protein.CONCLUSION: MLC 901 effectively decreased Hsp70 mRNA expression, HSP-70 and MMP-9 protein levels, infarct volume, and functional outcomes. MLC 901 could be a potential therapeutic agent for AIS.KEYWORDS: MLC 901, HSP-70, MMP-9, acute ischemic stroke
Comparative Analysis of Charge Recombination Dynamics in Dye-Sensitized Solar Cells with different Counter Electrodes Azizah, Evi Nur; Nurhayati, Nunik; Al Jazeera, Lalu Jihad; Yuliantini, Lia; Hatta, Mohammad; Amrillah, Tahta; Nursam, Natalita Maulani; Firdaus, Yuliar
Jurnal Elektronika dan Telekomunikasi Vol 25, No 1 (2025)
Publisher : National Research and Innovation Agency

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jet.703

Abstract

Counter electrodes are essential in dye-sensitized solar cells (DSSCs) for facilitating charge transfer and catalyzing the regeneration of the electrolyte, impacting overall efficiency. Common counter electrode materials include platinum (Pt), poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS), and graphene, each with distinct advantages and challenges. Pt, a traditional choice, offers excellent catalytic activity but is expensive and scarce. PEDOT:PSS, a conductive polymer, is cost-effective and easily deposited but often suffers from high recombination losses and lower efficiency. Graphene, known for its high conductivity and large surface area, is emerging as a promising alternative. However, a lack of comparative studies on how different counter electrode materials influence recombination dynamics limits the understanding needed for optimizing DSSC performance. This study addresses this gap by examining Pt, graphene, and PEDOT:PSS -based counter electrodes, analyzing their effects on charge transfer, recombination behaviour, and efficiency through J-V measurements, charge extraction, and transient photocurrent (TPC) as well as transient photovoltage (TPV) analyses. Graphene-based DSSCs show superior performance, achieving the highest photocurrent density and power conversion efficiency up to 5.12% at an intensity equivalent to 1 sun (100 mWcm-2), due to enhanced charge extraction and minimized recombination. TPC data reveal that graphene supports faster charge transport, while TPV analysis shows longer electron lifetimes than PEDOT:PSS-based DSSCs. In contrast, PEDOT:PSS-based DSSCs exhibit high recombination losses, lower photocurrent, and s-shaped J-V curves, indicating high resistance of limited charge transfer efficiency. These findings highlight graphene’s potential as an optimal counter electrode material for efficient, high-performance DSSCs.
Faktor – Faktor yang Mempengaruhi Indeks Harga Saham Gabungan (IHSG) Di Bursa Efek Indonesia (BEI) Periode 2020 - 2022 Nurjannah, Nurjannah; A, Abdul Samad; Bakri, Abdul Majid; Mujahid, Mujahid; Suyuthi, Nurmadhani Fitri; Hatta, Mohammad
Innovative: Journal Of Social Science Research Vol. 4 No. 2 (2024): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v4i2.9108

Abstract

Penelitian ini bertujuan untuk menganalis faktor – faktor yang mempengaruhi Indeks Harga Saham Gabungan pada periode 2020 – 2022 yang merupakan masa pandemi dan masa pemulihan setelah terjadi pandemi Covid – 19 di Indonesia. Indeks Harga Saham Gabungan (IHSG) merupakan indeks yang menunjukkan pergerakan harga saham secara umum yang tercatat di Bursa Efek Indonesia yang menjadi acuan perkembangan kegiatan di pasar modal Indonesia. Karena pergerakan IHSG sangat sulit di prediksi, sehingga sangat penting bagi investor mengetahui faktor – faktor apa saja yang berpengaruh dalam pergerakan IHSG dalam pengambilan keputusan investasi. Penelitian ini menganalisa Indeks Harga Saham Gabungan (IHSG) sebagai objek penelitian dengan menggunakan variabel independen yaitu Kurs (IDR/USD), BIRate, Inflasi, Dow Jones Industrial Average (DJIA), dan Sentimen Pasar. Penelitian ini menggunakan data bulanan selama periode 2020 – 2022 dengan metode Regresi Linier Berganda, yang menunjukkan hasil persamaan sebagai berikut : IHSG : 8027.751 – 0.378Kurs– 312Birate + 447Inf + 0.119Djia + 0.016Sentimen Pasar. Hasil uji statistik menunjukkan nilai adjusted R2 sebesar 0.885 yang artinya 88,5% variasi dari Indeks Harga Saham Gabungan (IHSG) dipengaruhi oleh variabel Kurs, BIRate, Inflasi, DJIA, dan Sentimen Pasar yang ada dalam penelitian ini. Sedangkan 11,5 % di pengaruhi oleh variabel lain yang tidak dijelaskan dalam penelitian ini. Sehingga, sangat penting mempertimbangkan variabel tersebut dalam pengambilan keputusan investasi
Measuring the Probability of Prohibition of the Spread of Wahhabism in Indonesia Based on Positive Law Suhli, Suhli; Hatta, Mohammad
Al-Daulah: Jurnal Hukum dan Perundangan Islam Vol. 12 No. 2 (2022): October
Publisher : Prodi Hukum Tata Negara Fakultas Syariah dan Hukum UIN Sunan Ampel Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15642/ad.2022.12.2.216-237

Abstract

The increasingly massive spread of Wahhabi ideology in Indonesia has given rise to reactive reactions among society, this is because Wahhabi preaching emphasizes the labeling of Bid'ah and Infidels towards other communities who have different understandings, and this has implications for the many horizontal conflicts that occur during public. Even though Indonesian society is known as a harmonious society amidst diversity and religion. This research is descriptive research with a qualitative approach, while the data collection technique used is a literature study. Then the data collected through the study of the text was compiled, then analyzed using the descriptive analysis method with a deductive mindset. The results of this research are that the Wahhabi ideology pioneered by Muhammad bin Abdul Wahab is an understanding that is oriented towards purifying the creed, which at that time was considered to have experienced many setbacks along with the development of the tarekat's teachings. However, the movement for this understanding is often accompanied by doctrines of heresy, syrk, and infidelity which create polarization in society. In this position, the state constitutionally regulates that every society has the right to believe in beliefs and express thoughts and attitudes following their conscience, but if these beliefs and statements of belief are carried out by causing divisions in society, then this is where the role of the State is needed to ensure peace. and the harmony that is the identity of the Indonesian nation is maintained, meaning that there needs to be a firm stance from the government regarding the spread of Wahhabi ideology, and the Perppu is an alternative as well as a legal instrument that is very possible for the Government to implement to stop the spread of Wahhabi ideology in Indonesia and at the same time reflects this attitude. The government is firm against anyone who destroys the diversity of Indonesian society Keywords: Wahabi, Labeling, Horizontal Conflict
Co-Authors A, Abdul Samad Al Jazeera, Lalu Jihad Andi Alfian Zainuddin Andi Asadul Islam Andi Kurnia Bintang, Andi Kurnia ASTUTIATI NURHASANAH Bakri, Abdul Majid Chaera, Ummi Evi Nur Azizah, Evi Nur Firdaus, Yuliar Hamid, Firdaus Handayani, Irda Hidayah, Najdah Ilsa Hunaifi, Ilsa Iskandar, Israini W. Jamaluddin, Balqis D. Karimah, Nihayatul Kusharsono, Sony Massi, Muhammad N. Mujahid Mujahid, Mujahid Nurjannah Nurjannah Nurmadhani Fitri Suyuthi Nursam, Natalita Maulani Ombo Satjapradja Panjaitan, Poltak BP Paulus Sugianto, Paulus Permana, Andi D. Putra, Suriya Adi Suhli, Suhli Tahta Amrillah Tammasse, Jumraini Wahid, Isra' Yuliantini, Lia Yusriyyah, Andi A. Zaenab, St