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Rosidah, Umi
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Journal : Jaringan Laboratorium Medis

 1 
Faktor Risiko Terjadinya Anemia pada Pasien Tuberculosis Paru dalam Fase Pengobatan Rosidah, Umi; Auliya, Qurrotu Ayuni; Wikandari, Ririh Jatmi; Widiyanto, Santo Yoseph Didik
Jaringan Laboratorium Medis Vol 6, No 2 (2024): November 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i2.12268

Abstract

Tuberculosis lungs is disease infectious disease caused by bacteria Mycobacterium tuberculosis. Tuberculosis is still a disease become threat health Indonesian society which  leads to illness , disability and death tall so that need existence mitigation. Research objectives know factor risk the occurrence of anemia in patients tuberculosis lungs in phase treatment . Study This is study retrospective analytic case control Study carried out at the Community Health Center Very Beautiful Subdistrict Genuk City of Semarang. Population all TB patients who are undergo treatment at the Community Health Center Bangetayu. Research sample This from the total population namely 34 case and control patients. The results of 34 respondents case control there is level hemoglobin in patients Tuberculosis lungs with anemia (case) as many as 17 respondents experienced decline hemoglobin levels, namely man with an average hemoglobin level of 12.2 gr/dL (7 respondents), women with The average hemoglobin level was 10.6 gr/dL (2 respondents). A total of 17 respondents non - anemic control , namely the majority is normal with type sex Woman with an average Hemoglobin level of 12.61 gr/dL (17 respondents ). Based on characteristics what kind sex male 29.41% and gender sex women 11.76%. Decrease hemoglobin levels , namely man with an average hemoglobin level of 12.2 gr/dL (5 respondents), women with average hemoglobin level 10.6 gr/dL (2 respondents). Based on characteristics of the type sex women 70.59% (24 respondents) and men 29.41% (10 respondents). Based on characteristics age category adults 64.71% (22 respondents), elderly 23.53% (8 respondents), infants and children 11.76% (4 respondents), and adolescents 0.00% (0 respondents). The results of the bivariate test of hemoglobin levels, age , and type sex there is connection between hemoglobin levels, age, and type sex to Pulmonary Tuberculosis patients in phase treatment. The most influential risk factor o to the occurrence of anemia in patients with pulmonary tuberculosis in phase treatment namely on the variables type sex that is own risk of 3,429. Next followed by variables hemoglobin levels that have risk of 0.370. Age No there is factor risk the occurrence anemia in pulmonary tuberculosis patients in phase treatment. The conclusion of this study is that hemoglobin levels and sex are risk factors for anemia in patients with pulmonary tuberculosis in the treatment phase. Anemia can affect the diagnosis, prognosis, complications, and response to tuberculosis therapy, so that tuberculosis patients can maintain nutritional intake and therapy compliance to suppress the progression of the disease.
Perbedaan Jumlah Trombosit Pada Pasien TB Sebelum dan Setelah 1 Bulan Mengonsumsi Obat Anti TB Taqarrasya, Asa; Wikandari, Ririh Jatmi; Rosidah, Umi
Jaringan Laboratorium Medis Vol 7, No 1 (2025): May 2025
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v7i1.12798

Abstract

Tuberculosis (TB) is still one of the infectious diseases with the highest mortality rate in the world. WHO stated that Indonesia is the third country in the world with the most TB cases. Semarang is the third province in Indonesia with the highest TB cases. Although the mortality rate is high, in reality TB can be treated and prevented. Anti-TB drugs as TB treatment agents can cause side effects, one of which is a decrease in the number of platelets. The purpose of this study was to determine the difference in the number of platelets in TB patients before starting treatment and after one month of treatment with Anti-TB drugs. The study population was new tuberculosis patients. The study sample was taken according to the established criteria and obtained as many as 24 people, who were examined twice, namely before treatment and after 1 month of treatment. The results of this study stated that the average number of platelets before starting TB treatment was 340.875 cells/μL and after one month of treatment with Anti-TB drugs was 281.958 cells/μL. The Wilcoxon test showed a P value = 0.009. There was a significant difference in the number of platelets before starting TB treatment and after one month of treatment with Anti-TB drugs. TB treatment can affect blood conditions, including platelets. Thus, patients and their families are expected to better  understand the importance of carrying out routine checks and not stopping treatment without medical consultation.
Kadar Asam Urat pada Perempuan Menopause Zahro, Safira; Rosidah, Umi
Jaringan Laboratorium Medis Vol. 3 No. 2 (2021): November 2021
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v3i2.8061

Abstract

Based on data from Riskesdas 2013, in line with increasing age the prevalence of joint disease has increased. The trigger is abnormal metabolic processes in the body and 10% of cases occur in postmenopausal women because the production of the hormone estrogen is disrupted. If treatment is not carried out, it will result in chronic gouty arthritis, resulting in paralysis. The purpose of this study was to determine the description of uric acid levels in postmenopausal women in Berahan Kulon Village, Wedung District, Demak Regency. The research method used is an observational study with a cross sectional approach. Of the 20 research subjects, 1 research subject had low uric acid levels, 9 research subjects had normal uric acid levels, and 10 research subjects had high uric acid levels. High uric acid levels were dominated by the age group 51-55 years, menopause duration 6-10 years and > 10 years, no history of heredity, and consumption of foods high in uric acid 3-5 times/week and > 5 times/week. The conclusion of this study is that 5% of postmenopausal women have low uric acid levels, 45% have normal uric acid levels, and 50% have high uric acid levels.
Deteksi Karsinoma Nasofaring Mengunakan Rapid Test Uji Imunokromatografi pada Petugas SPBU Afriansya, Roni; Rosidah, Umi; Sofyanita, Eko Naning
Jaringan Laboratorium Medis Vol. 5 No. 1 (2023): May 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i1.9337

Abstract

Nasopharyngeal cancer (NPC) is the 4th most common malignancy in Indonesia, after breast, cervical and lung cancer. The risk factors for this cancer are Epstein-Barr virus, gender, race, adult age 30-50 years, family history, drinking alcohol and smoking. The prevalence of NPC in Indonesia is 6.2/100,000, with nearly 13,000 new cases, but this is a small proportion that has been documented. Adham et al (2012) reported that NPC is the most common head and neck cancer (28.4%), with a male-female ratio of 2:4 and is endemic to the island of Java. The existence of knowledge about NPC starting from prevention, early detection, appropriate treatment will be able to help overcome problems caused by nasopharyngeal cancer. Early detection is very important. If NPC is found at an early stage, the cure rate is quite high, reaching 90%. The purpose of this study was to find out whether there were gas station workers in Semarang City who experienced NPC. This study used an analytic survey method with a cross-sectional approach. The results of the study of 20 Semarang City Gas Station officers found that the characteristics based on age were the most in the range 31-50, namely 70%. Characteristics based on gender of the 20 gas station attendants are all male (100%). Characteristics based on length of service are 1 - 10 years (35%), 11 - 20 years (35%) and 21 - 30 years (30%) respectively. Characteristics based on smoking history, 55% of respondents smoked and 45% did not smoke. And the NPC examination results of all respondents (100%) were NPC negative.
Analisis Kadar Timbal (Pb) Darah dan Malondialdehid (MDA) Pada Manusia Silver di Kota Semarang Rosidah, Umi; Hadipranoto, Ichsan
Jaringan Laboratorium Medis Vol. 5 No. 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9519

Abstract

The danger of lead in paint that is coated on the human body, silver can enter through the skin and will interact with proteins, DNA, RNA and oxidative stress. Formation of Reactive Oxygen Species (ROS) by lead can cause oxidative stress and is characterized by an increase in the enzymes catalase, malondialdehyde (MDA) and Oxidized glutathione (GSSG). The aim of this study was to analyze blood lead levels against Malondealdehyde (MDA) in silver humans in Semarang City. This study used an observational analytic study with a cross sectional approach to analyze the effect of lead levels on Malondialdehyde levels in silver humans in Semarang City using a t test to see differences in results based on length of work, length of exposure and age on lead levels, and the effect of lead on MDA. The results showed that from 20 human samples, the lowest lead level was 23.9 g/dl and the highest was 61.9 g/dl with an average blood lead level of 37.3 g/dl with an average blood lead level of 37.3 g/dl, and the lowest MDA level was 0.4 mg/L and the highest level is 1.74 mg/L with an average of 1.2 mg/L. Based on the data obtained from the t test, it shows a significant value (P-Value) of 0.610 which means > 0.05, this indicates that the decision taken is to reject H1 which means that there is no effect between the results of lead levels on the results of MDA levels.
Faktor Risiko Terjadinya Anemia pada Pasien Tuberculosis Paru dalam Fase Pengobatan Rosidah, Umi; Auliya, Qurrotu Ayuni; Wikandari, Ririh Jatmi; Widiyanto, Santo Yoseph Didik
Jaringan Laboratorium Medis Vol. 6 No. 2 (2024): November 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i2.12268

Abstract

Tuberculosis lungs is disease infectious disease caused by bacteria Mycobacterium tuberculosis. Tuberculosis is still a disease become threat health Indonesian society which  leads to illness , disability and death tall so that need existence mitigation. Research objectives know factor risk the occurrence of anemia in patients tuberculosis lungs in phase treatment . Study This is study retrospective analytic case control Study carried out at the Community Health Center Very Beautiful Subdistrict Genuk City of Semarang. Population all TB patients who are undergo treatment at the Community Health Center Bangetayu. Research sample This from the total population namely 34 case and control patients. The results of 34 respondents case control there is level hemoglobin in patients Tuberculosis lungs with anemia (case) as many as 17 respondents experienced decline hemoglobin levels, namely man with an average hemoglobin level of 12.2 gr/dL (7 respondents), women with The average hemoglobin level was 10.6 gr/dL (2 respondents). A total of 17 respondents non - anemic control , namely the majority is normal with type sex Woman with an average Hemoglobin level of 12.61 gr/dL (17 respondents ). Based on characteristics what kind sex male 29.41% and gender sex women 11.76%. Decrease hemoglobin levels , namely man with an average hemoglobin level of 12.2 gr/dL (5 respondents), women with average hemoglobin level 10.6 gr/dL (2 respondents). Based on characteristics of the type sex women 70.59% (24 respondents) and men 29.41% (10 respondents). Based on characteristics age category adults 64.71% (22 respondents), elderly 23.53% (8 respondents), infants and children 11.76% (4 respondents), and adolescents 0.00% (0 respondents). The results of the bivariate test of hemoglobin levels, age , and type sex there is connection between hemoglobin levels, age, and type sex to Pulmonary Tuberculosis patients in phase treatment. The most influential risk factor o to the occurrence of anemia in patients with pulmonary tuberculosis in phase treatment namely on the variables type sex that is own risk of 3,429. Next followed by variables hemoglobin levels that have risk of 0.370. Age No there is factor risk the occurrence anemia in pulmonary tuberculosis patients in phase treatment. The conclusion of this study is that hemoglobin levels and sex are risk factors for anemia in patients with pulmonary tuberculosis in the treatment phase. Anemia can affect the diagnosis, prognosis, complications, and response to tuberculosis therapy, so that tuberculosis patients can maintain nutritional intake and therapy compliance to suppress the progression of the disease.
Perbedaan Jumlah Trombosit Pada Pasien TB Sebelum dan Setelah 1 Bulan Mengonsumsi Obat Anti TB Taqarrasya, Asa; Wikandari, Ririh Jatmi; Rosidah, Umi
Jaringan Laboratorium Medis Vol. 7 No. 1 (2025): May 2025
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v7i1.12798

Abstract

Tuberculosis (TB) is still one of the infectious diseases with the highest mortality rate in the world. WHO stated that Indonesia is the third country in the world with the most TB cases. Semarang is the third province in Indonesia with the highest TB cases. Although the mortality rate is high, in reality TB can be treated and prevented. Anti-TB drugs as TB treatment agents can cause side effects, one of which is a decrease in the number of platelets. The purpose of this study was to determine the difference in the number of platelets in TB patients before starting treatment and after one month of treatment with Anti-TB drugs. The study population was new tuberculosis patients. The study sample was taken according to the established criteria and obtained as many as 24 people, who were examined twice, namely before treatment and after 1 month of treatment. The results of this study stated that the average number of platelets before starting TB treatment was 340.875 cells/μL and after one month of treatment with Anti-TB drugs was 281.958 cells/μL. The Wilcoxon test showed a P value = 0.009. There was a significant difference in the number of platelets before starting TB treatment and after one month of treatment with Anti-TB drugs. TB treatment can affect blood conditions, including platelets. Thus, patients and their families are expected to better  understand the importance of carrying out routine checks and not stopping treatment without medical consultation.
Co-Authors Agus Wijaya Asif Aunillah Auliya, Qurrotu Ayuni Auliya, Qurrotu A’yuni Basuni Hamzah Dwi Budi Santoso Efri Yulistika Eka Lidiasari Eko Heri Purwanto Faridi , Faridi Faridi Faridi Gatot Priyanto Hadipranoto, Ichsan Hamzah, Ruth Samantha Hermanto Hermanto Hermanto Hidayat, Yessy Syahfitri Ichsan, Onne Indriyani Syafutri, Merynda Khodijah, Citra Kholifah, Chintya Ayu Khozin, Khozin Kiki Yuliati Maftuhah Maftuhah Merynda Indriyani Syafutri Nura Malahayati Nurhakim Nurhakim Nurul Qomariyah Parwiyanti Parwiyanti Parwiyanti, Parwiyanti Permata Sari, Dwi Indah Rafiqah, Thara N Ramadhan, Hafidhuddin N Rikardo, Ricky Ririh Jatmi Wikandari Roni Afriansya Rosa Nastiti, Hilari Rio Sari, Dwi Indah Permata Sari, Ina Permata Sofyanita, Eko Naning SUGITO Sugito - Sujatmiko, Harumi Syafutri, Merynda Syafutri, Merynda I Syafutri, Merynda Indriayani Syaiful, Friska Taqarrasya, Asa Tobroni , Tobroni Tobroni Tobroni Tri Wardani Widowati Widiyanto, Santo Yoseph Didik Yanuariati, Anny Zahro, Safira