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All Journal KOVALEN: Jurnal Riset Kimia Jurnal Pendidikan Kimia (JPKim) Indonesian Journal of Pure and Applied Chemistry Jurnal Kartika Kimia Stannum : Jurnal Sains dan Terapan Kimia Jurnal Riset Sains dan Kimia Terapan CHEDS: Journal of Chemistry, Education, and Science Arfak Chem: Chemistry Education Journal BIO-CONS: Jurnal Biologi dan Konservasi Jurna Beta Kimia
Situmeang, Boima
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Education Energy Environmental Science Materials Science & Nanotechnology Social Sciences

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Journal : Jurna Beta Kimia

 1 
Potensi Nanoemulsi Ekstrak Daun Pirdot (Saurauia vulkani) dalam Meningkatkan Aktivasi Enzim Alpha-Amilase sebagai Alternatif Terapi Diabetes Mellitus Nasiro, Siti; Anjulita, Ratna; Setiawan, Eko; Afriyandi, Adfin; Situmeang, Boima
Jurnal Beta Kimia Vol 3 No 2 (2023): Volume 3, Nomor 2: November 2023
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jbk.v3i2.15164

Abstract

Tumbuhan pirdot (Saurauia vulcani Korth.) merupakan tanaman endemik yang banyak tumbuh di daerah Sumatera Utara yang memiliki berbagai manfaat khususnya sebagai alternatif obat tradisional, tetapi belum banyak diteliti dalam skala laboratorium. Riset ini bertujuan untuk mengetahui pengaruh nanoemulsi esktrak daun pirdot terhadap aktivitas antidiabetes. Nanoemulsi dibuat menggunakan virgin coconut oil sebagai fase minyak, tween 80 sebagai surfaktan, PEG 400 sebagai kosurfaktan, dan akuades sebagai fase air dengan massa ekstrak daun pirdot (1, 2, 3 dan 4 g). Pengujian stabilitas fisik yang dilakukan yaitu uji persen transmitan, uji sentrifugasi, uji pH, uji viskositas dan uji kelarutan. Ukuran partikel nanoemulsi terkecil pada formulasi F4 sebesar 1165 nm, sedangkan hasil aktivitas antidiabetes diperoleh % penghambatan terbaik nanoemulsi ekstrak daun pirdot terhadap enzim α-Amilase sebesar 80,41% pada F1.
Skrining Fitokimia dan Aktivitas Antioksidan Ekstrak Metanol Biji Buah Pare (Momordica charantia L.) Sriwijayanti, Sriwijayanti; Situmeang, Boima; Yulianti, Nani; Susvira, Dian; Widiyanto, Holisha
Jurnal Beta Kimia Vol 4 No 1 (2024): Volume 4, Nomor 1: Mei 2024
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jbk.v4i1.15487

Abstract

Antioksidan merupakan senyawa yang dapat merangkat radikal bebas. Salah satu tanaman yang diduga dapat merangkat senyawa radikal bebas adalah biji buah pare (Momordica charantia L.). Masyarakat telah menggunakan pare sebagai makanan sehari-hari dan juga telah lama dipercaya sebagai obat tradisional untuk mengobati berbagai macam penyakit. Tujuan dari penelitian ini adalah uji skrining fitokimia dan uji aktivitas antioksidan ekstrak metanol biji buah pare. Ekstraksi dilakukan dengan menggunakan metode maserasi. Uji skrining fitokimia dilakukan dengan menggunakan berbagai reagent kimia untuk analisis senyawa golongan alkaloid, fenoli, flavonoid, tannin, triterpenoid dan steroid. Uji Aktivitas antioksidan dengan menggunakan metode DPPH. Hasil uji skrining fitokimia didapatkan bahwa ekstrak metanol biji buah pare positif mengandung senyawa golongan alkaloid, flavonoid, fenolik, triterpenoid, steroid dan tanin. Hasil uji aktivitas antioksidan didapatkan nilai IC50 sebesar 137,99 ppm yang termasuk dalam kategori sedang.
Efektivitas Perendaman Larutan Nanas Queen Victoria sebagai Pereduksi Logam Fe pada Kerang Hijau (Perna viridis) Widiyanto, Holisha; Julianti, Julianti; Sriwijayanti, Sriwijayanti; Sari, Puspita; Situmeang, Boima; Susvira, Dian
Jurnal Beta Kimia Vol 4 No 2 (2024): Volume 4, Nomor 2: November 2024
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jbk.v4i2.18673

Abstract

Excessive Fe heavy metal contamination cause health problems for humans. One of the marine biota that is susceptible to heavy metal contamination is green mussels. Green mussels (Perna viridis) are a food that is very often consumed by humans. This Fe metal which derived with materials that are chelating agents such as citric acid, one of the fruits that contain citric acid is the Queen Victoria pineapple. The research aims to determine the effectiveness of soaking Queen Victoria pineapple solution in reduces Fe metal in green mussels. The pineapple solution immersion test was carried out with varying concentrations of 25, 50 and 75% with soaking times of 15, 30 and 45 minutes which were analyzed using inductively coupled plasma (ICP). The highest reduction results were at a concentration of 25% with a soaking time of 30 minutes, amounting to 60.58%.
Microemulsion of methanol extract of Tridax procumbens flower and its antibacterial activity against Streptococcus mutans and Enterococcus faecalis Wijayanti, Sri; Pradana, Agrin Febrian; Situmeang, Boima; Prastiwi, Dina Alva; Musa, Weny J.A.
Jurnal Beta Kimia Vol 5 No 1 (2025): Volume 5 Number 1, May 2025
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jbk.v5i1.21189

Abstract

Tridax procumbens (commonly known as Gletang flower) is a medicinal plant recognized for its antibacterial potential and is widely distributed across various habitats such as rice fields, plantations, and roadsides. Phytochemical screening of its methanolic flower extract revealed the presence of secondary metabolites, including alkaloids, flavonoids, steroids, phenols, terpenoids, and tannins, all of which contribute to its biological activities. This study aimed to develop a microemulsion formulation of T. procumbens methanolic extract and to evaluate its antibacterial activity against Streptococcus mutans and Enterococcus faecalis, two major oral pathogenic bacteria. The microemulsion was prepared using the sonication method and characterized by assessing its pH, transmittance, viscosity, physical stability, and particle size using a particle size analyzer. Antibacterial activity was tested using the Kirby-Bauer disk diffusion method. The results indicated that the microemulsion had particle sizes ranging from 300–1000 nm and demonstrated significantly higher antibacterial activity compared to the crude extract, suggesting improved solubility and enhanced bioactivity of the active compounds. This formulation holds promise as a natural antibacterial agent for the prevention of oral infections.
Co-Authors Afriyandi, Adfin Amin, Fauzan Anjulita, Ratna Asad, Hafidz Al Bilangi, Nurhayati Dewaldo, Dany Dzulhijar Eko Setiawan Fauji, Fajar Rizki Harianja, Lokky Sardomu Humesi, Lusi iin Farlina, iin Juliandoz Julianti Julianti, Julianti Lailatusholihah, Isna Mahardika, Micha Masyhuri, Aga Adi Mervina Rondonuwu Mohammad Rofik Usman Muhammad Akbar Musa, Weny J.A. Musa, Weny Junus Abdul Nani Yulianti Nasiro, Siti Ningrum, Sekar Ayu Ninik Triayu Susparini, Ninik Triayu Nurhayati Bialangi Pradana, Agrin Febrian Prastiwi, Dina Alva Puspita Sari Puspitasari Puspitasari Ramadhan, Muhammad Bagus Sagala, Iman Setyoko, Lintang Panji Sri Wijayanti Sriwijayanti Sriwijayanti, Sriwijayanti Suganda, Angga Susvira, Dian Wibowo, Arianto Widiyanto, Holisha