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SYSTEMATIC LITERATURE REVIEW: EFEK LATIHAN FISIK TERHADAP FUNGSI KOGNITIF LANSIA Rauf, Saidah; Kaimuddin, Riski Amalia; Olla, Marice Benga
Jurnal Keperawatan Indonesia Timur (East Indonesian Nursing Journal) Vol 3 No 2 (2023): Juli - Desember 2023
Publisher : Pusat Penelitian dan Pengabdian Kepada Masyarakat Poltekkes Kemenkes Maluku

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32695/jkit.v3i2.505

Abstract

Background: Cognitive decline is a common problem among the elderly. Cognitive disorders can be treated with an active lifestyle that includes regular physical activity. Objective: This study aims to examine the effect of physical exercise on the cognitive function of the elderly. Methods: The current study is a systematic review of published research articles using a Randomized Control Trial and a quasi-experimental design. The Garuda Portal and Pubmed databases were consulted for document identification. The articles were published between 2018 and 2021 in peer-reviewed journals and include respondents aged 45 years. No OR Control AND Gym OR Exercise AND Cognitive OR Memory AND Elderly OR Aging OR Elder were the keywords used for Pubmed searching. The keywords for portal garuda were Pengaruh DAN Latihan Fisik DAN Kognitif DAN Lansia. Results: The first stage of indentification were found 575 articles which fit to the keywords. After following the Prisma ways, a numbers of 9 articles were chosed for review. Exercise has been shown to improve cognitive function in every article reviewed. Aerobic and neuromuscular exercises are typically used. Conclusion: Physical exercise can help the elderly improve their cognitive function.
Studi Kualitatif Permasalahan Ketersediaan Tenaga Kesehatan Pada Puskesmas Di Provinsi Maluku Rauf, Saidah; Patinassarany, Lisbeth; Sahertian, Betty Anthoineta; Rasako, Hairudin; Latumenase, Rony Alexander; Lestaluhu, Santi Aprilian
Jurnal Kesehatan Terpadu (Integrated Health Journal) Vol 15 No 2 (2024): Jurnal Kesehatan Terpadu (Integrated Health Journal)
Publisher : Poltekkes Kemenkes Maluku

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32695/jkt.v15i2.586

Abstract

The Indonesian Ministry of Health's Medium-Term National Development Plan aims to ensure the availability of nine types of basic health workers in at least 83% of Puskesmas by 2024. However, the achievement in Maluku Province is far from the target (12%). This study aims to examine the experiences of health worker placements in Puskesmas in Maluku Province. A qualitative research design was employed, with data collected through in-depth interviews. The factors contributing to the shortage of healthcare personnel in public health centers (Puskesmas) include issues related to information systems healthcare workforce, economic factors, security and facilities, as well as factors of burnout and the imbalance in the production of healthcare personnel. The study concludes that the low availability of health workers in Puskesmas in Maluku is primarily caused by factors such as uneven distribution, lack of interest in serving remote areas, and issues related to data systems and technical competencies. It is recommended that the government enhance data systems and synchronization between health offices and Puskesmas, improve the equitable distribution of health workers, and provide incentives and training to improve the competencies and retention of health workers in remote areas of Maluku Province.
Cross-cultural adaptation and validation of the 9-item Indonesian HIV/AIDS Stigma Scale (InHASS-9) for the general population Arifin, Bustanul; Alkaff, Firas F.; Salamah, Sovia; Rauf, Saidah; Zulkarnain, Zulkarnain; Noor, Rasuane; Perwitasari, Dyah A.; Padmawati, Retna S.; Alkaff, Sylmina D.; Dwicahya, Bambang; Yuliet, Yuliet; Fajriansyah, Fajriansyah; Postma, Maarten J.; Kurniawan, Muh D.; R. Rokhman, Muhammad
Narra J Vol. 5 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i1.1305

Abstract

Stigma against people living with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) (PLWHA) poses significant health threats and contributes to the uncontrolled transmission of HIV. Although tools for measuring stigma against PLWHA have been validated in Indonesia, a previous study was geographically limited and conducted with small sample sizes. The aim of this study was to perform cross-cultural adaptation and validate the psychometric properties of the 9-item Indonesian HIV/AIDS Stigma Scale (InHASS-9) in the Indonesian general population. Utilizing a cross-sectional design, the study recruited 1,302 participants from six major islands in Indonesia. The validity of the instrument was determined using recognized group validity and construct validity, while internal consistency was evaluated using Cronbach's alpha. During the adaptation phase, nine simple items were finalized for inclusion in the scale. The findings revealed that the InHASS-9 instrument exhibited strong internal consistency, with Cronbach's alpha coefficient of 0.83, indicating high reliability. In conclusion, the InHASS-9 instrument is a valid and reliable tool for assessing the extent of social stigma associated with PLWHA in Indonesia.
Non-Severe Preeclampsia and Subclinical Inflammation: A Study of Cyclophilin A, NF-κB, PARP- 1, and Apoptosis in Human Placentas Resistantie, Novi; Wibowo, Noroyono; Prasmusinto, Damar; Jusman, Sri Widia Azraki; Yamin, Muhammad; Siregar, Nurjati Chairani; Prihartono, Joedo; Mose, Johannes Cornelius; Suhendro, Suhendro; Yunita, Ferdiana; Rosmanah, Lis; Margyaningsih, Nur Ita; Qotrunnada, Labibah; Roviqoh, Cindy Fawwaz; Rauf, Saidah
Indonesian Journal of Obstetrics & Gynecology Science Volume 8 Nomor 3 November 2025
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v8i3.947

Abstract

Objective: To compare the expression of CyP-A, NF-κB, PARP-1, and apoptotic index in Non-Severe Preeclampsia (NS-PE) and Normal Pregnancy (NP) and explore their roles in inflammation during preeclampsia.Methods: Conducted in Depok, Indonesia, the cross-sectional study involved 28 participants divided into NS-PE and NP groups based on ISSHP criteria. NP was defined as uncomplicated pregnancies at 38–40 weeks gestation. Placental weight was measured, and ELISA was used to assess biomolecule levels. Data were analyzed using T-tests or Mann-Whitney tests.Result: Maternal gestational age, body mass index, and leukocyte levels were significantly higher in NS-PE. The apoptotic index, measured by TUNEL assay, was also significantly elevated in NS-PE (41.56 ±24.87) compared to NP (23.96 ±18.79; p = 0.044). While CyP-A, PARP-1, and NF-κB levels were higher in NS-PE eventhough they were not statistically significant. Immunohistochemistry confirmed an overall increase in these molecules, supporting their clinical relevance.Conclusion: Despite the lack of statistical significance, increased inflammation and apoptosis in NS-PE may contribute to placental dysfunction and adverse pregnancy outcomes.Non-Severe Preeclampsia dan Inflamasi Subklinis: Studi CyP-A, NF-κB, PARP-1, dan Apoptosis pada Plasenta ManusiaAbstrak Tujuan: Penelitian ini bertujuan untuk mengetahui perbedaan ekspresi CyP-A, NF-κB, PARP-1, dan indeks apoptosis antara preeklamsia non-severe (NS-PE) dan kehamilan normal (NP), serta perannya dalam proses inflamasi pada preeklamsia.Metode: Metode penelitian yang digunakan dalam penelitian ini adalah cross-sectional. Penelitian ini dilakukan di Depok, Indonesia, dengan 28 partisipan yang dikelompokkan menjadi NS-PE dan NP berdasarkan kriteria ISSHP. Berat plasenta diukur dan kadar biomolekul dianalisis menggunakan ELISA. Uji T dan alternatif Mann-Whitney digunakan untuk analisis statistik.Hasil: Hasil penelitian menunjukkan bahwa usia kehamilan, indeks massa tubuh (IMT), dan kadar leukosit secara signifikan lebih tinggi pada NS-PE. Indeks apoptosis (TUNEL) juga lebih tinggi secara signifikan pada NS-PE (41,56 ±24,87) dibandingkan NP (23,96 ±18,79; p = 0,044). Kadar CyP-A, PARP-1, dan NF-κB lebih tinggi pada NS-PE meskipun tidak signifikan secara statistik, pemeriksaan IHK mengonfirmasi relevansi klinis peningkatan pada keseluruhan biomolekul tersebut. Kesimpulan: Meskipun signifikansi statistik rendah, peningkatan peradangan dan apoptosis pada NS-PE dapat menyebabkan disfungsi plasenta dan dampak buruk pada kehamilan.Kata kunci: Apoptosis; inflamasi; preeklamsia.