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All Journal Elementary: Islamic Teacher Journal JURNAL KEPEMIMPINAN DAN PENGURUSAN SEKOLAH Jurnal Ibriez : Jurnal Kependidikan Dasar Islam Berbasis Sains Tadarus: Jurnal Pendidikan Islam JSKK (Jurnal Sains Keolahragaan dan Kesehatan) Jurnal SEGAR Halaman Olahraga Nusantara : Jurnal Ilmu Keolahragaan Jurnal Golden Age Jurnal Fundadikdas (Fundamental Pendidikan Dasar) Journal of Coaching and Sports Science ITQAN: Jurnal Ilmu-ilmu Kependidikan Jurnal Akselerasi Merdeka Belajar dalam Pengabdian Orientasi Masyarakat (Jurnal AMPOEN) Jurnal Manajemen Pendidikan Islam The Elementary Journal Jurnal Pendidikan Dasar Jurnal Kesehatan Masyarakat
Wijayanto, Adi
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Religion Arts Humanities Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Jurnal Kesehatan Masyarakat

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Influence of Selenium Supplementation on Oxidative Stress and Inflammatory Response in High Intensity Exercise Irawan, Roy; Wahyudi , Heri; Bawono, Mokhamad; Roepajadi, Joesoef; Rimawati, Nanda; Wijayanto, Adi
Jurnal Kesehatan Masyarakat Vol. 20 No. 3 (2025)
Publisher : Universitas Negeri Semarang in collaboration with Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI Tingkat Pusat) and Jejaring Nasional Pendidikan Kesehatan (JNPK)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v20i3.4619

Abstract

Exhaustive exercise could increase oxygen consumption 10 to 20 times folds which can then increase oxidative stress which is characterized by an increase in Reactive Oxygen Species (ROS). Increased oxidative stress (ROS) during exercise could cause cell damage. Selenium is a trace element that is believed to have antioxidant and anti-inflammatory activity. Objectives: This study aimed to determine the effectiveness of a 28-day supplementation period on plasma MDA and HMGB1 levels after high-intensity exercise activities. Methods: This study was experimental, with a pretest-posttest control group design approach. A total of 28 Sports Science Department students at Universitas Negeri Surabaya who met the inclusion and exclusion criteria participated in the study. Through simple random sampling, participation was divided into 2 groups, namely the selenium group (SG) and the placebo (PL) group. Selenium supplements for SG were 200 mcg/day, and PL was 100mg corn starch capsules, both groups consumed in 28 days. Participants performed bench-stepping by Newham with 10 sets x 10 repetitions, with 1-minute intervals. Plasma MDA and HMGB1 measurements were carried out immediately after, 24 hours after, and 48 hours after bench-stepping. Data on changes in plasma levels of MDA and HMGB1 were tested using repeated measures ANOVA with a significance level of P<0.05. Result: there was a significant difference in the plasma MDA and HMGB1 between each group with the significance value of MDA that was p = 0.000 and the significance value of HMGB1 that was p = 0.000. Selenium supplementation for 28 days reduces the increase in oxidative stress (MDA) and increase in HMGB1 after high-intensity exercise activities.
Co-Authors Afifah, Fatin Agus Mukti Wibowo Agustina Nurlaila Eka Erfiana, Nita Ahmad Syaifuddin Alaziba, Balya Ari Kartiko, Ari Bawono, Mokhamad Dea Amelia, Dea Deaningtias, Amalira Dwi Astuti Wahyu Nurhayati Eni Setyowati Fatmawati, Septiana Gobel, Lisda Van Guntur Arie Wibowo, Guntur Arie JOESOEF ROEPAJADI Khoiriyah, Sheni Umi Lani, Ahmad Lestari, Gita Luthfiah, Jihan Nikmatuzakiyah, Ainun Nur Hasanah Patoni, Achmad Pramesti, Abelta Fetri Reghita Ayudia Pramudita, Adelya Qomara, Dhona Ayu Rachmantisna, Andika Revika, Aida Rimawati, Nanda Riskhayanti, Narulita Evia Rizal Fanani, Rizqy Roy Irawan Saputra, Nanda Saputri, Adelia Ctra Septian, Aditya Budi Shaleh, Shaleh Sigit Priatmoko Sulastio, Agus Syahfitri, Puja Sri Taman, Mona Refaat Wahyudi , Heri Wiku Aji Sugiri Yuwono, Tia Dita Putri Latifa Zaini, Muhamad