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All Journal BERKALA SAINSTEK Jurnal Inovasi Pendidikan Kimia Jurnal Bahan Alam Terbarukan JURNAL FISIKA Indonesian Journal of Chemical Science PAEDAGOGIA Spektra: Jurnal Fisika dan Aplikasinya Walisongo Journal of Chemistry Sarwahita : Jurnal Pengabdian Kepada Masyarakat Jurnal Komunikasi Pendidikan JURNAL PENDIDIKAN MIPA Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Jurnal Pengabdian Nasional (JPN) Indonesia Jurnal Farmasi dan Sains Indonesia (JFSI) INDRA: Jurnal Pengabdian kepada Masyarakat Journal of Science and Technology Research for Pharmacy Jurnal Pengabdian Nasional (JPN) Indonesia Science and Community Pharmacy Journal
Alighiri, Dante
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Journal : Science and Community Pharmacy Journal

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Isolation and Antifungal Activity of Caryophyllene from Clove Leaf Oil (Syzygium aromaticum L.) on Mahogany Leaf Composites Alighiri, Dante
Science and Community Pharmacy Journal Vol. 1 No. 1 (2022): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v1i1.248

Abstract

Mahogany leaf composites mostly consist of cellulose which is easily weathered due to rotting fungi. One way to overcome this is to use anti-weathering chemicals. Chemical potential as a natural anti-weathering and abundant in Indonesia is caryophyllene compounds as a by-product in the eugenol industry which processes it from clove leaf oil. In this work, isolation and antifungal activity of caryophyllene from clove leaf oil on mahogany leaf composites was evaluated. Based on GC-MS analysis of clove leaf oil is known that eugenol and caryophyllene has yielded 42.83% and 23.87%, respectively. Selective extraction by using sodium hydroxide solution (2,5% NaOH, the ratio of oil to solution is 1:5) and fractional distillation under reduced pressure (Distillate fraction, DF P= -76 cmHg, R=5:1) and continued redistilled are needed to isolate of caryophyllene. Redistilled can improve the purity, then distillate collected while the temperature changed with a purity of 99.10%. Meanwhile, mahogany leaf composite has been successfully synthesized from mahogany leaves by using a polyurethane binder and glass fiber as reinforcement. Minimum inhibitory concentration (MIC) of caryophyllene was determined. The composite was coated with caryophyllene and evaluated for its antifungal activity against Aspergillus fumigatus. Observation using a CCD camera (Charge Couple Device) microscope with a magnification of 50x shows the growth of fungal spores on the composite surface. As a result, A. fumigatus can be inhibited by caryophyllene oil in a 1.2% concentration on mahogany leaf composite
Co-Authors - Jumaeri Abdullah, Ravely Adhitya Akhmad Darmawan Akhmad Darmawan Anis Susanti Anwar, Ahmad Faisal Apriliana Drastisianti Apriliana Drastisianti Apriliana Drastisianti Basyirun Budiyanto, Saraswati Putri Choirunnisa, Fadhillah Cici Fatmala Citra Pramesti Dian Fithra Permana Dian Marini Dian Marini Drastisianti, Apriliana Drastisianti, Apriliana Edy Cahyono Eko Budi Susatyo Endang Susilaningsih Enni Suwarsi Ervan Bagus Haditya F Widhi Mahatmanti Fatmala, Cici Firnanda, Indah Putri Haditya, Ervan Bagus Harjono Iis Naeni Putri Wahyuni Iis Naeni Putri Wahyuni Imam Syafi’i Kirana, Kurnia Galuh Candra Lia Intan Humairoh Lis Setiyo Ningrum Margareta Rahayuningsih Nugroho Edi K Masturi Masturi Nasyatal Ula Hawa Hazuwa Nasyatal Ula Hawa Hazuwa Nina Oktarina Ni`ma, Neli Syahida Nur Rahayu Utami Pratiwi Dwijananti Rahmaniar, Ranita Samuel Budi Wardhana Kusuma Savitri, Annisa Aulia Setyo Yuwono Sigit Priatmoko Sri Nurini Sri Wahyuni Sucipto, Lukman Syafi'i, Imam Syafi’i, Imam Umar Faruq Muttaqiin Umar Faruq Muttaqiin Uswatun Hasanah Wawan Rustyawan Widodo, Naufaldi Bani Willy Tirza Eden, Willy Tirza Wiwik Kartika Sari