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Journal : Jurnal Analis Medika Biosains (JAMBS)

Differences In Lipid Profiles In Diabetes Mellitus Patients Based On Cigarette Consumption Fihiruddin, Fihiruddin; Putri, Ananda Kinanti; Manu, Thomas Tandi
Jurnal Analis Medika Biosains (JAMBS) Vol 12, No 1 (2025): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v12i1.369

Abstract

Diabetes mellitus (DM) is a metabolic condition characterized by hyperglycemia and abnormalities in protein, lipid and carbohydrate metabolism. Smoking is one thing that can cause DM. Smoking as a risk factor for insulin resistance. An increase in lipid profile is directly related to insulin resistance, which increases blood sugar levels by increasing lipolysis and decreasing lipogenesis in fat cells. To determine differences in lipid profiles (total cholesterol, HDL, LDL, triglycerides) in diabetes mellitus sufferers based on cigarette consumption. This research is Analytical Observational using secondary data with an approach Cross Sectional. The sampling method used in this research was purpossive sampling. Data was collected using medical record data on the lipid profile of 48 samples of diabetes mellitus sufferers who consumed cigarettes and analyzed using statistical tests Paired Sample t-test. Were that the mean levels of total cholesterol, HDL, LDL and triglycerides in diabetes mellitus patients who consumed less than 20 cigarettes per day were 228.8 mg/dL, 49 mg/dL, 127.4 mg/dL and 144.4 mg/dL. The mean levels of total cholesterol, HDL, LDL and triglycerides in diabetes mellitus sufferers who consumed more than 20 cigarettes per day were 185.3 mg/dL, 32.7 mg/dL, 116.7 mg/dL and 148 mg/dL. There is a significant difference between the HDL lipid profile in diabetes mellitus patients who consume less than 20 cigarettes per day and more than 20 cigarettes per day.
Efek Imunostimulator Kubis (Brassica Oleracea Var. Capitata Alba) Terhadap Titer Imunoglobulin G (Ig G) Pada Kelinci Yang Diinduksi Dengan Sel Darah Merah Domba Inayati, Nurul; Fihiruddin, Fihiruddin; Getas, I Wayan
Jurnal Analis Medika Biosains (JAMBS) Vol 7, No 2 (2020): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v7i2.196

Abstract

Kubis (Brassica aloracae var.capitata alba) adalah salah satu sayuran yang berpotensi sebagai imunostimulator. Kubis banyak megandung nutrien yang mempunyai nutrisi tinggi seperti vitamin, mineral, dietary fiber, glukosinolates, polyphenol dan phenolic acid. Disamping itu juga kubis mengandung peptida yang berperan sebagai imunoglobulin production stimulating factor (IPSF) sehingga dapat berfungsi sebagai imunostimulator yang akan dapat meningkatkan sistem imun tubuh dengan cara merangsang peningkatan sistem fagositik dan produksi interleukin 5. Penelitian ini merupakan penelitian ekprimental dengan desain statistic group comparation yang bertujuan mengetahui pengaruh pemberian kubis (Brassica oleracea capitata alba) untuk meningkatkan pembentukan immunoglobulin G (IgG) pada kelinci yang diinduksi dengan sel darah merah domba 2 %. Hewan coba yang digunakan dikelompokkan menjadi 2 kelompok yaitu kelompok perlakuan dan kelompok kontrol. Hewan coba yang akan digunakan adalah kelinci dengan berat 700 – 800 gr sebanyak 20 ekor yang akan dibagi menjadi dua kelompok yaitu kelompok perlakuan dan kontrol. Metode pemeriksaan yang digunakan adalah dengan uji heamaglutinasi dengan mengamati terjadinya aglutinasi antara serum yang diambil dari darah kelinci dengan sel darah merah domba   (SDMD) 2 %. Rata-rata titer Imunoglobulin G (IgG) pada kelompok perlakuan dan kelompok kontrol masing-masing adalah 2.26 µl/ml dan 1.62 µl/ml. Hasil uji statistik dengan paired t test dengan tingkat kepercayaan 0,95 % menunjukkan bahwa terdapat perbedaan yang signifikan ( p < 0,05) antara kelompok perlakuan dan kelompok kontrol yaitu dengan nilai signifikannya adalah 0,043.
Resistance Analysis Of Several Antibiotics in Samples of Clinical Isolates With Salmonellosis Wahyuni, Shohifatul; Pauzi, Iswari; Jiwintarum, Yunan; Fihiruddin, Fihiruddin
Jurnal Analis Medika Biosains (JAMBS) Vol 11, No 1 (2024): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v11i1.357

Abstract

Typhus is a systemic infection caused by Salmonella typhi bacteria, which is usually transmitted through contaminated food or drink, usually treated with antibiotics. Inappropriate use of antibiotics causes various problems, one of which causes resistance. This resistance problem has become a global problem, including in Indonesia where there is an increase in bacterial resistance from 2013 which is 40%, 2016 as much as 60% and in 2019 reached 60.4%, due to irrational use of antibiotics so that bacteria become resistant to drugs. This study aims to determine the description of resistance to several antibiotics in clinical isolates of patients with Salmonellosis This study is a pre-experimental study, with a cross sectional approach. The samples used were pure isolates of Salmonella typhi bacteria obtained from blood samples of Salmonellosis patients, then tested for resistance with 5 different types of antibiotics (Ciprofloxacin, Amoxicillin, Levofloxacin, Cefotaxime and Sulfamethoxazolle-trimethopim) with the disk method (Kearby Beaure). The number of experimental units is 25 units, with the number of replications is 5 replications. The results showed that the five types of antibiotics were sensitive to Salmonella typhi bacteria with the highest antibiotic sensitivity being Ciprofloxacin while the antibiotic that had the lowest sensitivity was Amoxicillin. From the results, it can be concluded that the resistance test of the five antibiotics (Ciprofloxacin, Amoxicillin, Levofloxacin, Cefotaxime and Sulfamethoxazolle-trimethopim) is sensitive. 
Pengaruh Konsumsi Tuak Terhadap Kadar Asam Urat Pada Masyarakat Dewasa di Desa Jagaraga Timur Juliantini, Ni Komang; Fihiruddin, Fihiruddin; Jiwantoro, Yudha Anggit
Jurnal Analis Medika Biosains (JAMBS) Vol 9, No 1 (2022): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v9i1.256

Abstract

Tuak is a type of alcoholic drink made from palm sugar. Excessive consumption of tuak continuously can increase the levels of uric acid in the body. Uric acid is the end product of purine metabolism. This study aimed to determine the effect of tuak consumption of uric acid levels in the adult community in East Jagaraga Village. This research is an analytical observation using a cross-sectional approach. The sampling technique was a simple random sampling of 48 people, namely 24 adults that consumed tuak and 24 adults who did not consume tuak. Data analysis in SPSS used an independent sample t-test. The average uric acid levels in 24 respondents that consumed and did not consume tuak were 7.46 mg/dl and 4.92 mg/dl, respectively. The results show that there is an effect of tuak consumption uric acid levels in the adult community in the East Jagaraga Village, this is shown in a probability value (p = 0.000) <0.05 then Ho is rejected and Ha is accepted. From these results, it can be concluded that the consumption of tuak in the long term affects increasing uric acid levels.
Detection of Nicotine in Urine of Passive Smokers Exposed to Cigarette Smoke From Smoking and Non-Smoking Families Aolani, Almira Zaida; Fihiruddin, Fihiruddin; Urip, Urip; Tatontos, Erlin Yustin
Jurnal Analis Medika Biosains (JAMBS) Vol 12, No 2 (2025): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v12i2.459

Abstract

Passive smokers are vulnerable to nicotine exposure, which can increase the risk of health problems. Nicotine is a chemical compound in tobacco that causes dependence and can be detected in urine as metabolites like cotinine. This study aimed to detect nicotine in the urine of passive smokers exposed to cigarette smoke from smoking and non-smoking families in Genggelang Village. An analytical observational method with a cross-sectional design was used. The sample consisted of 24 respondents selected by purposive sampling, divided into two groups. Urine samples were tested using a nicotine test strip and analyzed descriptively. The results showed that among 12 passive smokers from smoking families, one respondent tested positive for nicotine. Meanwhile, all 12 respondents from non-smoking families tested negative. These findings indicate that passive smokers living with smoking families are still at risk of nicotine exposure through second hand smoke in the household environment.