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All Journal Majalah Patologi Indonesia Sumatera Medical Journal SCRIPTA SCORE Scientific Medical Journal Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Indonesian Journal of Cancer Jurnal Kedokteran STM (Sains dan Teknologi Medik)
Laksmi, Lidya Imelda
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Clinicopathologic Profile of Lung Cancer Patients at Murni Teguh Memorial Hospital in 2023 Putri, Rosni Amanda; Lumongga, Fitriani; Permatasari, Amira; Laksmi, Lidya Imelda
Indonesian Journal of Cancer Vol 19, No 4 (2025): December
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i4.1371

Abstract

Background: Lung cancer is the most prevalent type of cancer worldwide, with a mortality rate of 1,817,469. This study aims to determine the clinicopathology of lung cancer patients in Murni Teguh Memorial Hospital.Methods: This is a descriptive study with a cross-sectional design. Clinical data were obtained from the medical records of lung cancer patients at Murni Teguh Memorial Hospital in 2023. The inclusion criteria were lung cancer patients who had been diagnosed histopathologically, while patients with incomplete medical records were excluded from the study. The data were processed using the Statistical Package for the Social Sciences (SPSS) software version 27.Results:  A total of 63 lung cancer patients were mostly (41.3%) aged 51-60 years. 48 subjects (76.2%) have been identified as male. Clinical symptoms of shortness of breath were found in 22 (34.9%) subjects, and the majority (47.6%) had a tumour size of T4. Based on histopathological classification according to WHO, 35 (55.5%) lung cancer patients mostly have adenocarcinoma.Conclusions: Lung cancer patients at Murni Teguh Memorial Hospital in 2023 presented with advanced disease, as reflected by the high proportion of large tumor size (T4) and respiratory symptoms such as shortness of breath. These findings highlight the tendency for late-stage presentation of lung cancer and underscore the need for improved early detection strategies and timely diagnostic interventions in this population. 
Diffuse Large B-Cell Lymphoma (DLBCL) of the Mesocolon in A Young Man with Intussusception: A Case Report Laksmi, Lidya Imelda; Muhar, Adi Muradi; Hasibuan, Winda Syahfitri
Indonesian Journal of Cancer Vol 20, No 1 (2026): March
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v20i1.1449

Abstract

Introduction: Diffuse Large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma (NHL), accounting for 25% to 30% of NHL cases. Diffuse large B-cell lymphoma (DLBCL) commonly happens in the seventh decade and often arises in the lymph nodes but can also present as an extra nodal disease. Nodal DLBCL involves the lymph nodes and does not involve the organ under the lymph nodes. In this case, we want to report a case of 25 men diagnosed with intussusception caused by nodal mesocolon enlargement, and histomorphology examinations revealed that the nodal enlargement is DLBCL. Here we reported a case of 25 years old man diagnosed with invagination caused by nodal mesocolon enlargement and, histomorphology examinations revealed the nodal enlargement is DLBCL.Case Presentation: We reported a case of 25 years old man complaints nausea, vomiting, abdominal pain, and was diagnosed with intussusception. Macroscopic examination showed nodal enlargement without colon mucosal involvement. Microscopic examination showed a relatively uniform and monotonous distribution of lymphoid cells with large cell sizes, enlarged nuclei with a round to oval shape, vesicular chromatin, amphophilic cytoplasm and some foci of tumour cells arranged in loose stroma. Macrophage and atypical mitoses were found. Immunohistochemical examination results were as follows: CD 117 (-), DOG 1 (-), CK (-), CD 45 (+), Myogenin (-), MyoD1 (-), CD20 (-), CD3 (-), Ki67 50%, CD 20 (+), CD3 (-), CD 10 (-), BCL6 (-), MUM1 (+).Conclusion: Diffuse large B-cell lymphoma (DLBCL) can occur in gastrointestinal as extra nodal lymphoma. The mesocolon contains many lymph nodes, but gastrointestinal lymphoma usually involves the gastrointestinal tissue. This case reports a case of 25 years old man who presents with intussusception caused by DLBCL in nodal mesocolon without colon involvement.
Co-Authors Alamanda, Intan Nefia Alferraly, T. Ibnu Basrul, Mohd. Yuwanda Betty betty betty Chrestela, Jessy Chrestella, Jessy Delyuzar, Delyuzar Fiandani, Fatma Hasibuan, Winda Syahfitri Intan, T. Kemala Kadri, Sayed Muhammad Khairunnisa, Ash'trid Krishna Moorthi, Priya Darshini Listiyaningsih, Listiyaningsih Lubis, M. Nadjib Dahlan Lukito, Joko S. Lumongga, fitriani Mariedina, Causa Trisna Muhar, Adi Muradi Nadjib Dahlan Lubis Permatasari, Amira Putri, Rosni Amanda Rachmatsyah, M. Yusuf Rangkuti, Deske Muhadi Rezeki, Dewi Sri Siti Aisyah Soekimin Soekimin, Soekimin T. Shafira Yaznil, Muhammad Rizki Yetty Machrina