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All Journal Jurnal Gema Ngabdi Jurnal Abdi Insani Journal of Multidisciplinary Applied Natural Science Jurnal Pendidikan dan Pengabdian Masyarakat Jurnal Kefarmasian Indonesia
Hamdin, Candra Dwipayana
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Social Sciences Other

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Efektivitas Formula Krim Tabir Surya Berbahan Aktif Ekstrak Etanol Biji Wali (Brucea javanica L. Merr) Amini, Almira; Hamdin, Candra Dwipayana; Muliasari, Handa; Subaidah, Windah Anugrah
Jurnal Kefarmasian Indonesia VOLUME 10, NOMOR 1, FEBRUARI 2020
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v10i1.2066

Abstract

High intensity of ultraviolet (UV) radiation causes several adverse effect such as erythema, sunburn, pigmentation, early senescence, and skin cancer. These effects can be prevented by using sun protection product. Wali (Brucea javanica L. Merr) is one of natural plants that contain phenol and flavonoid. These compounds are proven to have sunscreen effect. The purposes of this studies are to formulate and evaluate the effectivity of oil-in-water-type sunscreen cream using 1% ethanol extract of Wali seed. The sunscreen cream is developed by using a fusion method and the evaluation of the effectivity is conducted in vivo on the skin of mice (Mus musculus). The formulated sunscreen cream is then tested for its physical properties, including homogenity, pH, spreadability, adhesion, and stability. The effectivity of the formulated cream is also tested by observing the formation of erytema on the skin of mice (Mus musculus). Erythema appearing on the mouse skin is analyzed with ImageJ and SPSS v23 using the one way anova method. The results showed that the ethanol extract of Wali seeds could be formulated into sunscreen cream. Furthermore, the formulated cream was also able to protect the mice skin against the formation of erythema significantly compared to negative controls (p
Pharmacist Goes to School: Promoting DAGUSIBU As A Pharmaceutical Education Tool for Adolescents Saputra, Yoga Dwi; Ulya, Tuhfatul; Hasina, Raisya; Aini, Siti Rahmatul; Puspitasari, Candra Eka; Andanalusia, Mahacita; Lisnasari, Baiq Risky Wahyu; Hamdin, Candra Dwipayana
Jurnal Gema Ngabdi Vol. 6 No. 3 (2024): JURNAL GEMA NGABDI
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jgn.v6i3.522

Abstract

Drug misuse is an urgent public health issue, often arising from a lack of knowledge about proper medication use. Research shows that over half of the medications worldwide are used irrationally. The DAGUSIBU program (Dapatkan, Gunakan, Simpan, Buang or known as Get, Use, Store, Dispose) was developed as a solution to address this issue by providing education on proper medication management. This community service activity was organized by the Pharmacy Study Program and the Pharmacy Professional Education Program (PSPPA), Faculty of Medicine and Health Sciences (FKIK), Universitas Mataram, on August 9, 2024, at Kesuma Catholic High School in Mataram. The primary goal of this activity was to teach students the correct ways to obtain, use, store, and dispose of medications, as well as to introduce the pharmacist profession and the Pharmacy program at UNRAM to high school students. The activity included interactive presentations on DAGUSIBU, an introduction to the pharmacist profession, and a quiz competition as an evaluation method. The quiz encouraged active student participation, with prizes to boost motivation. Despite challenges such as varying levels of student comprehension and time constraints, the activity successfully improved students’ understanding of rational drug use and introduced career opportunities in pharmacy. Overall, this activity proved effective in raising student awareness and knowledge, positively impacting their health literacy.
EDUKASI DAN DEMONSTRASI PEMANFAATAN TANAMAN KATANG-KATANG (IPOMOEA PES- CAPRAE) DALAM PENGOBATAN TRADISIONAL DI DUSUN MUARA PUTAT, DESA PEMENANG TIMUR, LOMBOK UTARA Hasina, Raisya; Aini, Siti Rahmatul; Hamdin, Candra Dwipayana; Ulya, Tuhfatul; Ananta, Muhammad Naufal Farras; Alamanda, Baiq Irzana Putri; Putri, Dheden Nurhani Bija; Yazid Maula
Jurnal Abdi Insani Vol 12 No 7 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i7.2704

Abstract

Ipomoea pes-caprae (katang-katang) adalah tanaman liar pesisir yang tersebar luas di wilayah tropis dan subtropis serta mampu beradaptasi di lingkungan berkadar garam tinggi. Perannya penting dalam ekosistem pantai, seperti mencegah erosi dan mendukung restorasi vegetasi. Daunnya umum digunakan secara tradisional untuk pengobatan gangguan pencernaan dan penyakit kulit. Di Dusun Muara Putat, Lombok Utara, tanaman ini belum dimanfaatkan secara optimal meski potensinya besar secara ekologis, terapeutik, dan ekonomis. Kegiatan ini bertujuan untuk meningkatkan wawasan dan keterampilan warga Dusun Muara Putat, Kabupaten Lombok Utara, dalam memanfaatkan katang-katang sebagai alternatif pengobatan tradisional. Pendekatan yang digunakan mencakup penyuluhan berupa sosialisasi dan praktik langsung. Kegiatan ini menggabungkan pendekatan sosialisasi dan praktik langsung, diawali dengan pre-test untuk mengukur pengetahuan awal peserta. Materi mencakup identifikasi morfologi tanaman katang-katang, kandungan bioaktif, manfaat farmakologis, dan teknik pengolahan sederhana. Peserta dilatih secara langsung, lalu dievaluasi melalui post-test untuk mengukur peningkatan pemahaman. Hasil menunjukkan peningkatan pengetahuan peserta, dengan rata-rata nilai pre-test sebesar 60 yang meningkat menjadi 80 pada post-test. Selain itu, peserta juga menunjukkan kemampuan praktik dalam mengolah tanaman untuk pengobatan rumah tangga. Penyuluhan melalui metode sosialisasi dan demonstrasi langsung dengan pendekatan partisipatif ini terbukti efektif dalam meningkatkan pengetahuan masyarakat Dusun Muara Putat tentang pengobatan tradisional, khususnya dalam pemanfaatan tanaman katang-katang (Ipomoea pes-caprae). Kesimpulannya, penyuluhan partisipatif di Dusun Muara Putat efektif meningkatkan pemahaman dan keterampilan masyarakat dalam pemanfaatan katang-katang sebagai obat tradisional.  
Edukasi Literasi Dini Obat Herbal bagi Siswa Sekolah Dasar dalam Rangka Optimalisasi Pemanfaatan Tanaman Keluarga (Toga) Hamdin, Candra Dwipayana; Rohmayani, Febriana Putri; Anindiya, Naya Wahyu; Tarinda, Sabita
Jurnal Pendidikan dan Pengabdian Masyarakat Vol. 9 No. 1 (2026): Februari
Publisher : FKIP Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppm.v9i1.10657

Abstract

Indonesia memiliki potensi besar dalam pemanfaatan tanaman obat keluarga (TOGA), namun literasi masyarakat, khususnya anak-anak, masih rendah. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan literasi dini siswa sekolah dasar terhadap obat herbal melalui edukasi interaktif dan praktik langsung. Program dilaksanakan di SDN 2 Bentek, Kabupaten Lombok Utara, dengan melibatkan 30 siswa kelas VI. Metode yang digunakan adalah quasi-experimental one group pretest-posttest design untuk menilai efektivitas edukasi terhadap peningkatan pengetahuan. Kegiatan terdiri atas penyuluhan mengenai jenis dan manfaat tanaman obat, demonstrasi pembuatan jamu tradisional, serta praktik penanaman TOGA di lingkungan sekolah. Hasil menunjukkan adanya peningkatan signifikan skor pengetahuan siswa dari hasil pretest ke posttest, dengan sebagian besar siswa mampu menjawab benar ≥80% soal setelah intervensi. Selain itu, observasi partisipatif menunjukkan peningkatan antusiasme dan kemampuan siswa dalam mengenal serta menjelaskan manfaat tanaman obat. Kegiatan ini membuktikan bahwa edukasi berbasis praktik langsung efektif dalam menanamkan kebiasaan memanfaatkan tanaman obat secara bijak sejak usia dini. Program DOCIL (Duta Obat Cilik Lombok) diharapkan menjadi model edukasi berkelanjutan dalam memperkuat literasi kesehatan dan pelestarian kearifan lokal berbasis TOGA.
Dual Antifungal and Immunoregulatory Actions of Topical Silver Nanoparticles from Piper ornatum Extract in Cutaneous Candida albicans Infection Dewi, Firli Rahmah Primula; `Mustofa, Laila Al Azizi; Hamdin, Candra Dwipayana; Geraldi, Almando; Lim, Vuanghao; Pramudya, Manikya; Hayati, Alfiah; Hajar, Versa Rachmania
Journal of Multidisciplinary Applied Natural Science Articles in Press
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/jmans.2774-3047.374

Abstract

Cutaneous Candida albicans infection is characterized by persistent inflammation, epidermal damage, and dysregulated immune responses. Silver nanoparticles (AgNPs) have emerged as promising antifungal agents with additional immunomodulatory properties; however, their effects on skin pathology and local immune responses during candidiasis remain incompletely defined. This study aimed to investigate the therapeutic effects of a topical AgNP-based cream in a murine model of C. albicans–induced skin infection. AgNPs were green-synthesized using an aqueous leaf extract of Piper ornatum. A murine model of cutaneous C. albicans infection was established, and infected mice were treated topically with AgNP-based cream formulations at concentrations of 4% or 6%. Disease severity was assessed through macroscopic skin evaluation and histopathological analysis. Immune modulation was examined by flow cytometric analysis of CD4⁺ T-cell subsets expressing TNFα and IL-17, as well as CD11b⁺ myeloid cells expressing IL-6 and IL-10. Untreated infected mice exhibited severe cutaneous pathology, including persistent erythema, erosive lesions, epidermal hyperkeratosis, and acanthosis. These changes were accompanied by marked immune dysregulation, characterized by expansion of CD4⁺IL-17⁺ T-cells, suppression of TNFα-producing CD4⁺ T-cells, increased IL-6 expression, and reduced IL-10 production in CD11b⁺ myeloid cells. Topical AgNP treatment significantly ameliorated macroscopic and histological skin damage, restoring epidermal architecture toward normal. Immunologically, AgNP therapy attenuated pathological Th17 responses, reduced IL-6-producing myeloid cells, enhanced IL-10 expression, and maintained TNFα at controlled levels. Both AgNP concentrations were effective, with the 4% AgNP formulation showing slightly superior normalization of epidermal thickness and inflammatory markers. Overall, topical AgNP-based cream effectively alleviated cutaneous C. albicans infection by combining antifungal activity with coordinated immunomodulation of both adaptive and innate immune responses. By suppressing excessive IL-17– and IL-6–driven inflammation while promoting regulatory immune pathways, AgNP treatment supports tissue repair and immune homeostasis, highlighting its potential as a therapeutic strategy for cutaneous candidiasis.
Co-Authors Aini, Siti Rahmatul Alamanda, Baiq Irzana Putri Alfiah Hayati Almando Geraldi Amini, Almira Ananta, Muhammad Naufal Farras Anindiya, Naya Wahyu Candra Eka Puspitasari Firli Rahmah Primula Dewi Hajar, Versa Rachmania Hasina, Raisya Lim, Vuanghao Lisnasari, Baiq Risky Wahyu Mahacita Andanalusia Manikya Pramudya Muliasari, Handa Putri, Dheden Nurhani Bija Rohmayani, Febriana Putri Saputra, Yoga Dwi Tarinda, Sabita Ulya, Tuhfatul Windah Anugrah Subaidah Yazid Maula `Mustofa, Laila Al Azizi