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All Journal JBIO: jurnal biosains (the journal of biosciences) AGRIVITA, Journal of Agricultural Science CHEMPUBLISH JOURNAL Sains Natural: Journal of Biology and Chemistry CARADDE: Jurnal Pengabdian Kepada Masyarakat Jurnal Pendidikan dan Pembelajaran Sains Indonesia (JPPSI) Jurnal Studi Guru dan Pembelajaran Cendekia Journal of Pharmacy Jurnal Pendidikan dan Pembelajaran Sains Indonesia (JPPSI) Amina Jurnal Ilmiah Bakti Farmasi
Devy Susanty
Program Studi Kimia, Universitas Nusa Bangsa
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Social Sciences

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FORMULA DAN AKTIVITAS ANTIBAKTERI SEDIAAN OBAT KUMUR DENGAN EKSTRAK BUNGA TELANG (Clitoria ternatea L.) Indriani, Selli; Susanty, Devy; Nurlela; Nurhayati, Lany
Jurnal Ilmiah Bakti Farmasi Vol 10 No 1 (2025): Jurnal Ilmiah Bakti Farmasi
Publisher : Lembaga Penelitian & Pengabdian Kepada Masyarakat (LPPM) STIFI Bhakti Pertiwi Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61685/jibf.v10i1.143

Abstract

Karies gigi menjadi salah satu penyakit gigi dan mulut yang paling banyak ditemukan pada masyarakat. Bakteri utama penyebab karies yaitu Streptococcus mutans. Penggunaan obat kumur yang mengandung bahan antibakteri merupakan salah satu cara untuk mengatasi permasalahan kesehatan gigi dan mulut. Penelitian ini bertujuan untuk memanfaatkan ekstrak bunga telang (Clitoria ternatea L.) sebagai zat aktif dalam sediaan obat kumur, mengetahui karakteristik sediaan obat kumur ekstrak bunga telang, serta mengetahui aktivitas antibakteri ekstrak bunga telang dan obat kumur ekstrak bunga telang terhadap bakteri S. mutans. Pada penelitian ini dilakukan uji determinasi tanaman, ekstraksi dengan metode maserasi menggunakan pelarut etanol 70%, uji skrining fitokimia, serta uji aktivitas antibakteri ekstrak bunga telang terhadap bakteri S. mutans menggunakan metode difusi cakram. Obat kumur ekstrak bunga telang diformulasikan dengan variasi konsentrasi ekstrak bunga telang 0% (F0);1,5% (F1); 3% (F2); 4,5% (F3). Sediaan obat kumur diuji organoleptik, pH, berat jenis, viskositas dan aktivitas antibakteri terhadap S. mutans. Uji aktivitas antibakteri ekstrak bunga telang terbukti mampu menghambat pertumbuhan bakteri S. mutans pada konsentrasi 100% dengan diameter zona hambat sebesar 11 mm (kategori kuat). Formulasi obat kumur dengan penambahan ekstrak bunga telang 4,5% (F3) menunjukkan perbedaan yang signifikan dengan formula tanpa ekstrak, dengan diameter hambat 1,5 mm.
Efficacy of Three Variants of Dioscorea bulbifera L. Leaf Extract as Termiticides to Control the Dry Wood Termites (Cryptotermes cynocephalus Light) Oksari, Ade Ayu; Faridha, Faridha; Susanty, Devy; Rizki, Fathan Hadyan; Rohimatun, Rohimatun; Wanda, Irvan Fadli; Arinana, Arinana; Dadang, Dadang
AGRIVITA Journal of Agricultural Science Vol 47, No 3 (2025)
Publisher : Faculty of Agriculture University of Brawijaya in collaboration with PERAGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17503/agrivita.v47i3.4208

Abstract

The leaves of Dioscorea bulbifera L. have chemical compounds that have the potential as bioinsecticides. This study aims to determine the effectiveness of polar, semi-polar, and non-polar fractions in D. bulbifera leaf extract as bioinsecticides. The research design used was a Factorial, Completely Randomized Design consisting of two factors with five repetitions using the contact method against Cryptotermes cynocephalus. The first factor was the type of solvent: non-polar solvents, semi-polar solvents, and polar solvents. The second factor was concentration, with a range of 5%, 4%, 3%, 2%, and 1%. Based on the results, the D. bulbifera leaves in the polar fraction contain alkaloids, flavonoids, phenols, triterpenoids, and saponins. The semi-polar fraction contains alkaloids, phenols, and steroids. The non-polar fraction contains alkaloids, phenols, and triterpenoids. GC-MS identification showed 20 metabolite compounds as potential as botanical insecticides. The highest termite mortality was in the non-polar fraction, with a 4% concentration of 32.80% (equivalent to a corrected mortality of 27.58%). The semi-polar fraction (3.20 g and 15.10%) at a concentration of 5% (2.58 g and 12.19%), showed the best reduction in test weight and degree of damage. This result indicates that D. bulbifera is an effective bioinsecticide in the repellent group.
Ekstrak chlorella sp. yang dikultur pada media limbah ternak ayam Susanty, Devy; Oksari, Ade Ayu; Izani, Rizky
Chempublish Journal Vol. 4 No. 2 (2019): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v4i2.7615

Abstract

Untuk menguragi pencemaran lingkungan yang berasal dari limbah ternak ayam broiler, kotoran ayam dapat dimanfaatkan sebagai media tumbuh. Pada penelitian ini, Chlorella sp (inaCC M39) dikultur pada media limbah ternak ayam Broiler dengan konsentrasi 20 gram/L. Limbah yang digunakan merupakan kotoran ayam broiler yang telah kering dan dilakukan uji untuk mengetahui kadar Nitrogen (N), fosfor (P), dan Kalium (K). Uji N menggunakan metode kjhedal, Uji P dan K dengan spektrofotometri. Kadar N pada limbah kotoran ayam yaitu 0,8%, kadar P sebesar 0,041%, dan kadar K sebesar 112,58 mg/L. Pertumbuhan Chlorella sp diamati selama 16 hari setiap 48 jam dengan spectofotometer pada panjang gelombang 680 nm. Chlorella sp mencapai puncak pertumbuhan pada hari ke-14. Ekstraksi biomassa Chlorella sp dilakukan bertingkat dengan pelarut kloroform dan dilanjutkan dengan pelarut metanol, lalu dilakukan uji fitokimia. Ekstrak metanol Chlorella sp diketahui memiliki kandungan steroid dan saponin. Kata Kunci : Limbah, Ayam Broiler, Media, Chlorella sp., Ekstrak ABSTRACT Extract of Chlorella sp. Cultured in Chicken Livestock Waste Media To reduce environmental pollution from broiler chicken waste, chicken manure can be used as a growing medium. In this study, Chlorella sp. (inaCC M39) was cultured on Broiler chicken waste media with a concentration of 20 grams / L. The waste used was dried broiler chicken manure and tested to determine levels of Nitrogen (N), phosphorus (P), and Potassium (K). The test for N uses the kjhedal method, P and K were tested with spectrophotometry methods. The content of N in chicken manure are 0.8%, P are 0.041%, and K are 112.58 mg / L. Chlorella sp. growth was observed for 16 days every 48 hours with a spectrophotometer at a wavelength of 680 nm. Chlorella sp. reaches peak growth on day 14. Chlorella sp. biomass was extracted with chloroform solvents and followed by methanol solvents, then phytochemical tests were performed. Chlorella sp. methanol extract is known to contain steroids and saponins. Keywords: Waste, Broiler Chicken, Media, Chlorella sp., Extract
Co-Authors Ade Ayu Oksari Ade Ayu Oksari Agus Ismanto Alifah Nuranzani Apikah, Lailan Arinana Arinana Ary Triyanto Choerunnas, Paqih DADANG DADANG Dian Arrisujaya Faridha Faridha Faridha, Faridha Gladys Ayu Paramita Kusumah Wardhani Hamza Mursandi Hana Laelasari I Gusti Ayu Manik Widhyastini I Gusti Ayu Manik Widhyastini Indriani, Selli Irna Diah Mumpuni Irvan Fadli Wanda Irvan Fadli Wanda Izani, Rizky Lany Nurhayati Mamay Maslahat Mursandi, Hamza Nia Yuliani Nurlela Nurlela Nurlela Nurlela Nurlela Nurlela, Nurlela Oktavio Rosani Resha Ratna Kusumah Risma Aprilia Rizki, Fathan Hadyan Rizky Izani Rohimatun Rohimatun, Rohimatun RTM Sutamihardja RTM Suthamihardja Siti Hadiati Mardiah Siti Qur'aniati Wahyono Wahyono Winda Yulliyanti Yuliani, Nia Zakia Arachmah Siregar