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GAMBARAN TINGKAT PENGETAHUAN MENGENAI PAPARAN SOLAR ULTRAVIOLET PADA KULIT MAHASISWA AGROEKOTEKNOLOGI UNUD ANGKATAN 2019 Wicaksono, Rafael Lilik; Praharsini, I Gusti Ayu Agung; Sudarsa, Prima Sanjiwani Saraswati; Suryawati, Nyoman
E-Jurnal Medika Udayana Vol 12 No 1 (2023): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2023.V12.i01.P10

Radiasi solar ultraviolet (SUV) dapat membawa dampak baik sekaligus dampak buruk bagi kesehatan jika terpapar pada kulit dalam rentang waktu tertentu. Negara Indonesia memiliki letak yang berdekatan dengan garis ekuator sehingga intensitas SUV (UVI) cenderung tinggi setiap tahunnya, peningkatan UVI juga diketahui sejajar dengan peningkatan dampak buruk paparannya pada kulit. Penelitian di Bali menunjukan prevalensi kanker kulit sebagai dampak terburuk paparan SUV lebih tinggi pada para pekerja outdoor dengan usia lanjut, padahal mekanisme terjadinya kanker terjadi akibat paparan kronis sejak usia muda. Karena itu, penelitian ini bertujuan untuk mengetahui tingkat pengetahuan terhadap paparan SUV pada kulit dari Mahasiswa Agroekoteknologi Universitas Udayana Angkatan 2019, yang berisiko karena ke depannya bekerja di lahan outdoor. Penelitian ini dilakukan untuk mencari tahu distribusi data dari tingkat pengetahuan Mahasiswa berdasarkan variabel sosiodemografi jenis kelamin dan usia Mahasiswa. Metode penelitian yang dipakai adalah studi deskriptif dengan desain penelitian potong lintang (cross-sectional) dan pengambilan sampel dilakukan secara total sampling dengan kriteria inklusi dan eksklusi. Instrumen penelitian yang ada menggunakan kuesioner oleh studi Suryantari, dkk. (2019). Jumlah sampel yang didapat sebesar 102 Mahasiswa. Data yang didapat diolah dan disajikan dalam bentuk proporsi menggunakan SPSS v.26. Berdasarkan hasil penelitian, proporsi tingkat pengetahuan baik (mean ± standar deviasi) dari jenis kelamin laki-laki didapati sebanyak sebanyak 92,82% (12,048 ± 2,284), jenis kelamin perempuan 96,67% (12,900 ± 1,674), usia 18-19 tahun 96,3% (12,519 ± 1,718), Usia 20-22 tahun 94,67% (12,56 ± 2,081). Penelitian ini menyimpulkan bahwa Mahasiswa Agroekoteknologi Universitas Udayana Angkatan 2019 memiliki pengetahuan yang baik akan paparan SUV pada kulit. Kata kunci: Solar Ultraviolet, Tingkat Pengetahuan, Jenis Kelamin, Usia

Serum Interleukin-6 Levels are Positively Correlated with the Severity of Acne Vulgaris Triatmakusuma, Yogi; Praharsini, I Gusti Ayu Agung; Darmaputra, I Gusti Nyoman; Winaya, Ketut Kwartantaya; Karna, Ni Luh Putu Ratih Vibriyanti; Puspawati, Ni Made Dwi
Journal La Medihealtico Vol. 5 No. 1 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i1.1056

Acne vulgaris is a chronic inflammatory disease that affects the pilosebaceous unit. This disease occurs on the skin of the face, body, back, and other areas of the body, and can leave scars on the skin which can be temporary or permanent. Recent data shows that the inflammatory process is the initial process in the pathogenesis of acne, several pro-inflammatory cytokines, one of which is interleukin 6 (IL-6), which plays a role in acne vulgaris. Analytical observational study with a cross-sectional approach. The research was carried out from February - November 2023 at the Skin and Venereology Polyclinic, RSUP Prof. Dr. I.G.N.G. Ngoerah Denpasar and the Clinical Pathology Laboratory of Prof IGNG Ngoerah Hospital. The sample consisted of 47 samples of patients with acne and 20 samples without acne aged 8 - 45 years who were selected through consecutive sampling according to inclusion and exclusion criteria. A sample of 3 milliliters of venous blood is taken which will then be checked for IL-6 with an ELISA kit. Data analysis with SPSS version 24 and p value <0.05 is significant. The mean IL-6 serum levels in the acne group was 110.2 ± 88.3 pg/ml while in the non-acne group it was 26.7 ± 23.7 pg/ml. There was a significant difference in the category of IL-6 levels in the acne and non-acne groups (95% CI 55.1 - 155.3, p<0.001). The correlation analysis of IL-6 levels with the severity of acne was strongly positive (r=0.951, p<0.001).

Characteristics of skin aging at the Dermatology and Venereology Outpatient Unit at Prof. dr. I Goesti Ngoerah Gde Ngoerah General Hospital, Denpasar from January to December 2019 Tiara Evangelista; Ni Made Dwi Puspawati; Luh Made Mas Rusyati; I Gusti Ayu Agung Praharsini
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 6, Issue 2 (December 2023)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/balidervenaesthj.v6i1.33

Background: Skin aging is a complex biological process influenced by intrinsic and extrinsic factors. In addition, national data regarding skin aging is still scant. This research was carried out to learn the characteristics of skin aging at the Dermatology and Venereology outpatient unit of Prof. Dr. I G. N. G. Ngoerah General Hospital, Denpasar, in January-December 2019. Methods: This research is a quantitative descriptive study with a cross-sectional design. Sampling was carried out by total sampling with research subjects consisting of skin-aging patients at the Dermatology and Venereology Outpatient Unit of Prof. dr. I G. N. G. Ngoerah General Hospital in January-December 2019. The data collected consists of age, gender, smoking history, alcohol consumption history, body mass index, usage of sunscreen, duration of sun exposure, and Glogau scale classification. Descriptive analysis was carried out using SPSS ver. 23. Results: Twenty cases of skin aging were included. Most cases of skin aging were in the age group of 36-45 years old, all of whom were female, all of whom had no history of smoking, all of whom had no history of alcohol consumption, most body mass index classification was overweight, most do not use sunscreen, the duration of the sun exposure is mostly 30 minutes-6 hours, and the highest classification of the Glogau scale is group III. Conclusion: In this study, body mass index, usage of sunscreen, and duration of sun exposure are the main factors affecting skin aging.

Effect of 8% Purple Sweet Potato Extract Cream on Wrinkle Reduction, Skin Moisture, and Elasticity Laksmi, I Gusti Ayu Agung Mini; Praharsini, I Gusti Ayu Agung; Karmila, I Gusti Ayu Agung Dwi; Rusyati, Luh Made Mas; Suryawati, Nyoman; Winaya, Ketut Kwartantaya
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 1 (2025): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V37.1.2025.1-8

Background: Purple sweet potato has been shown to contain anthocyanins, polyphenols, flavonoids, and tannins that act as antioxidants and have the potential to correct signs of aging in the skin, such as wrinkles, lack of hydration, and pigmentation. Purpose: to known the potential of 8% purple sweet potato extract for wrinkles, moisture, and elasticity. Methods: A one-group experimental study with pre and post-test assessment. The subject is women with photoaging aged 30-45 years. A pre-test was conducted by examining wrinkles using the Glogau scale and a simple A-one scanner, treatment with 8% purple sweet potato extract cream for 6 weeks, and then a post-test at the end of the 6th week to check wrinkles, moisture, and elasticity using a simple A-one scan. Statistical tests using the SPSS program, version 25.0. The analysis performed was descriptive statistical and comparative analysis using a paired T test. Result: A total of 25 respondents with a mean age ± SD of 38.22 ± 4.23 years, the most Glogau scale in type 2 is 22 respondents (88%), the most sun exposure for 30 minutes per day is 14 respondents (56%). The degree of wrinkles decreased after treatment -4.960±1.353 [95% CI -7.681-(-2.239); P=0.001]. The degree of moisture increased after treatment 8.840±2.990% (95% CI 2.829-14.851; P=0.005. The degree of elasticity increased after treatment 14.840±4.623 (95% CI 5.544-24.136; P=0.002). Conclusion: 8% purple sweet potato extract can reduce the degree of wrinkles, improve the degree of skin moisture, and improve the degree of skin elasticity.

A Retrospective Three-Year Analysis of Adult Scabies at a Tertiary Referral Center in Bali, Indonesia I Gusti Ayu Agung Praharsini; Luh Putu Sustiana Kartika Sari
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 9 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i9.1388

Background: Scabies, a parasitic infestation by Sarcoptes scabiei var. hominis, is a global health challenge with significant morbidity, particularly in tropical climates. While often studied in community settings, the profile of adult patients presenting to tertiary care facilities remains under-documented. This study aimed to delineate the clinical-demographic characteristics of adult scabies patients at a major referral hospital in Bali, Indonesia, to better understand this specific patient study. Methods: A retrospective, descriptive study was conducted utilizing electronic medical records from the Dermatology and Venereology outpatient clinic at Prof. Dr. I.G.N.G. Ngoerah General Hospital from January 2021 to December 2023. Following a total sampling method based on strict inclusion and exclusion criteria, data from 38 adult patients with a clinical diagnosis of scabies were extracted. The analysis focused on descriptive statistics to summarize patient demographics, contact history, and prescribed therapeutic regimens. Results: The study of 38 patients had a mean age of 34.1 ± 2.5 years. A male predominance was noted (n=22, 57.9%). The highest frequency of cases was in the 40-49 year age bracket (n=9, 23.7%). Most patients had completed senior high school (n=17, 44.7%) and were employed in the private sector (n=20, 52.6%). A family history of scabies was prevalent (n=18, 47.4%). While indirect transmission via shared clothing was rare (reported by only 7.9%), direct contact through bed sharing with at least one other person was common (n=24, 63.2%). The standard therapeutic protocol was combination therapy, with topical 5% Permethrin and oral antihistamines being the most frequent regimen (n=24, 63.2%). Conclusion: Adult scabies patients at this tertiary center are typically middle-aged, educated, working males. Transmission is overwhelmingly linked to intimate household contact, highlighting the inefficiency of fomite-based spread compared to direct skin-to-skin contact. The standard use of combination therapy reflects a proactive clinical approach to managing both the parasitic infestation and the complex immunologic cascade of pruritus. These findings provide a crucial clinical baseline for this specific patient population.

Characteristic of Herpes Zoster in the Elderly at Prof. Dr. I.G.N.G. Ngoerah General Hospital: An Epidemiologic Study Hosea, Felicia Emiliana; Praharsini, I Gusti Ayu Agung
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 2 (2025): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikkk.V37.2.2025.84-89

Background: Herpes zoster is a disease caused by the reactivation of the latent varicella zoster virus. Herpes zoster is the most common infection found in the elderly population. Epidemiologic data on herpes zoster infection among the elderly population in Bali remain limited. Purpose: The purpose of this study is to evaluate the characteristics of herpes zoster infection in elderly patients in order to provide clinical decision-making related to the management and prevention of herpes zoster in the elderly. Methods: This study uses a retrospective descriptive and gets its information from the medical records of herpes zoster patients at the Dermatovenereology Polyclinic at Prof. Dr. I.G.N.G. Ngoerah General Hospital from January 2019 to June 2022. The study population consisted of patients aged 60 years or older who were diagnosed with herpes zoster and received treatment at the polyclinic during the study period. Result: This study found that 33 elderly patients were diagnosed with herpes zoster. The age group 60-69 years found the most herpes zoster, with 18 (54.6%) patients and 17 (51.5%) male patients. The elderly patients had more comorbidities, which are 22 (66.7%) patients, with the majority having cancer, 7 of 22 patients (31.8%). The thoracic dermatome affected 13 patients (39.4%), multidermatome involvement affected 16 patients (48.4%), and post-herpetic neuralgia affected 22 patients (66.7%). Conclusion: This study found that elderly herpes zoster patients were mostly in the age group of 60-69 years, had cancer comorbidities, and involved multidermatomes.

A Retrospective Three-Year Analysis of Adult Scabies at a Tertiary Referral Center in Bali, Indonesia I Gusti Ayu Agung Praharsini; Luh Putu Sustiana Kartika Sari
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 9 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i9.1388

Background: Scabies, a parasitic infestation by Sarcoptes scabiei var. hominis, is a global health challenge with significant morbidity, particularly in tropical climates. While often studied in community settings, the profile of adult patients presenting to tertiary care facilities remains under-documented. This study aimed to delineate the clinical-demographic characteristics of adult scabies patients at a major referral hospital in Bali, Indonesia, to better understand this specific patient study. Methods: A retrospective, descriptive study was conducted utilizing electronic medical records from the Dermatology and Venereology outpatient clinic at Prof. Dr. I.G.N.G. Ngoerah General Hospital from January 2021 to December 2023. Following a total sampling method based on strict inclusion and exclusion criteria, data from 38 adult patients with a clinical diagnosis of scabies were extracted. The analysis focused on descriptive statistics to summarize patient demographics, contact history, and prescribed therapeutic regimens. Results: The study of 38 patients had a mean age of 34.1 ± 2.5 years. A male predominance was noted (n=22, 57.9%). The highest frequency of cases was in the 40-49 year age bracket (n=9, 23.7%). Most patients had completed senior high school (n=17, 44.7%) and were employed in the private sector (n=20, 52.6%). A family history of scabies was prevalent (n=18, 47.4%). While indirect transmission via shared clothing was rare (reported by only 7.9%), direct contact through bed sharing with at least one other person was common (n=24, 63.2%). The standard therapeutic protocol was combination therapy, with topical 5% Permethrin and oral antihistamines being the most frequent regimen (n=24, 63.2%). Conclusion: Adult scabies patients at this tertiary center are typically middle-aged, educated, working males. Transmission is overwhelmingly linked to intimate household contact, highlighting the inefficiency of fomite-based spread compared to direct skin-to-skin contact. The standard use of combination therapy reflects a proactive clinical approach to managing both the parasitic infestation and the complex immunologic cascade of pruritus. These findings provide a crucial clinical baseline for this specific patient population.

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