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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Jurnal Penelitian dan Pembelajaran Fisika Jurnal Pemberdayaan: Publikasi Hasil Pengabdian Kepada Masyarakat Makara Journal of Health Research Ahmad Dahlan Medical Journal Biomedika
Ariani, Rizka
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Arts Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Social Sciences Other

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Analisis Landasan Ilmu Pengetahuan dan Teknologi Pendidikan dalam Pengembangan Multimedia Interaktif Ariani, Rizka; Festiyed, Festiyed
Jurnal Penelitian Pembelajaran Fisika Vol 5, No 2 (2019)
Publisher : Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (150.152 KB) | DOI: 10.24036/jppf.v5i2.107439

Abstract

Research conducted includes descriptive research. On descriptive statistics without analyzing and making conclusions that apply to the public. The population in this study are articles and online books analyzed. The samples in this study are some of the articles analyzed, taken according to the topic. Educational institutions, especially school path education, must be able to accommodate and anticipate the development of science and technology. Teaching material should be the result of the development of the latest science and technology, both related to the results of information acquisition, as well as how to obtain that information and utilize it for the community. With the advancement in technology, it is possible to produce interactive learning media that are interesting and fun for teaching and learning. As Suheri (2006) argues that multimedia gives a pleasant impression of helping the learning process in remembering and multimedia learning in the classroom is not a new phenomenon, but advances in computer technology enable multimedia to be developed to present learning material interactively
Molecular Detection for Japanese Encephalitis and Chikungunya Virus as Etiology Agent for Dengue-Like Fever Symptoms Ariani, Rizka; Sudiro, Tjahjani M; Dewi, Beti E
Makara Journal of Health Research Vol. 22, No. 3
Publisher : UI Scholars Hub

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Abstract

Background: Acute fever with dengue-like fever symptoms with headache, rash, arthritis, perifer bleeding like ptechie and rinhorrhea are symptoms that often complained by patient and it may be caused by arboviruses infection. Arboviruses are very endemic in Indonesia, especially Dengue Virus (DENV), Japanese Encephalisitis Virus (JEV), and Chikungunya Virus (CHIKV) that causing similar symptoms. Molecular detection is very important to confirm the etiology for adequate management. Methods: This study investigated the etiological agent using one step real time RT reverse transcription polymerase chain reaction (RT PCR) method and SYBR Green I as fluorescent binding dye reporter. The viruses that were investigated were JEV and CHIKV. Primer design was using online software NCBI. Those primers fulfill the good primer requirements and can be used as material in RT PCR reaction. Results: The optimum temperature for all primers were at 60 °C. The limit detection of JEV primer was 4355 copy DNA every reaction. Cross reactivity between all primers with DENV serotype 2 RNA and false positive result using healthy person sample were not found. Conclusions: This study has optimized condition RT PCR protocol that can be used as diagnostic tools for patient with dengue-like fever symptoms.
Overview of Tuberculosis Epidemiology at PKU Muhammadiyah Bantul Hospital in 2021-2023 Sukirto, Novi; Yuniasih, Dewi; Prisilla, Elvina; Umam Kurniawan, Nurcholid; Budi Rahayu, Ana; Awisarita, Wiwara; Ariani, Rizka
Ahmad Dahlan Medical Journal Vol. 5 No. 1 (2024): May 2024
Publisher : Universitas Ahmad Dahlan

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Abstract

The number of tuberculosis cases reported in Bantul Regency in 2022 was 732 cases. Aims this study to determine the epidemiological picture of tuberculosis in PKU Muhammadiyah Bantul Hospital in 2023. Research method: The research method applied in this study was the analytical observational method. The design in this study was cross-sectional. Tuberculosis cases at PKU Muhammadiyah Bantul Hospital in 2021-2023 experienced fluctuations and based on gender, the most cases were 54% males, the most tuberculosis patients were in the age group of 55-64 years, 86% of patients resided in Bantul Regency, the classification of tuberculosis was more in pulmonary tuberculosis, namely 72%, based on the results of the thoracic examination, 68% were known to be positive for tuberculosis, 17% of tuberculosis patients were accompanied by diabetes mellitus and 2% of tuberculosis patients were confirmed HIV positive. The conclusion is Patients at PKU Muhammadiyah Bantul Hospital were more male than female. Most of the patients in the age group of 55-64 years, and resided in Bantul. The TB diagnosis is most pulmonary tuberculosis, with more positive thoracic examination results, fewer patients with diabetes mellitus, and fewer HIV-positive tuberculosis patients. Keywords: epidemiology, characteristics, tuberculosis
Health promotion and screening in elderly congregate of PCM (Pimpinan Cabang Muhammadiyah) north Banguntapan to improve quality of life Dwi Rizkita, Leonny; Nisa, Afifah Khoiru; Ariani, Rizka; Aristiani, Windy
Jurnal Pemberdayaan: Publikasi Hasil Pengabdian Kepada Masyarakat Vol. 8 No. 2 (2024)
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jpm.v8i2.10139

Abstract

Common non-communicable disease such as hypertension or diabetes mellitus is often found in elderly. Irregular medical check-up and uncontrolled medicine could lead into complications such as stroke and kidney failure. Elderly is also considered vulnerable and fragile, thus memory disturbance also sometimes occurs. Although these problems are inevitable due to ageing process, many strategies can be applied to prevent to complications. For example, by giving regular check-ups and knowledge transfer through health promotion, as well as early screenings. Thus, the aims for the community service are increasing the elderly’s understanding, forming proactive elderly and providing laboratory screenings. The method used is interactive presentation about non-communicable disease, medical check-ups for blood glucose, uric acid and total cholesterol level, and memory to quality of life assessment for elderly. The target of this service is elderly congregate of Jihad (Pengajian Ahad) Pagi of PCM (Pimpinan Cabang Muhammadiyah) North Banguntapan, Bantul Regency, DIY (Daerah Istimewa Yogyakarta). The result of the implementation of the service activity is increasing knowledge and awareness in regards of non-communicable and mental disease in elderly, as well as medical screenings data for next service project.
Inhibitory effects of rambutan (Nephelium lappaceum l.) leaves ethanolic extract on Methicillin-Resistant Staphylococcus aureus (MRSA) and Streptococcus pyogenes Rizkita, Leonny Dwi; Ariani, Rizka; Farid, Muhammad; Rastrani, Ardestya; Ramadhania, Widya Aryana; Putri, Ratna Aprillia Eka
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 15, No 2 (2024): December 2024
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v15i2.40155

Abstract

Antimicrobial resistance poses a global health threat, with Methicillin-Resistant Staphylococcus aureus (MRSA) and Streptococcus pyogenes contributing to the highest mortality rates among Gram-positive pathogens over the last three decades. The search for alternative antimicrobial agents has increasingly concentrated on natural products. Rambutan (Nephelium lappaceum L.), a widely used ethnomedicinal plant in Indonesia, is recognized for its numerous health benefits, including its antimicrobial properties. Despite extensive phytochemical studies on various parts of rambutan, the specific inhibitory effects of its leaf extract against MRSA and S. pyogenes have yet to be explored. This study aimed to evaluate the antimicrobial activity of ethanolic rambutan leaf extract against MRSA and S. pyogenes. The extract was prepared using maceration with 96% ethanol, followed by qualitative phytochemical screening, which confirmed the presence of flavonoids (blackish-blue reaction with FeCl3) and tannins (reddish hue with HCl). Antibacterial activity was assessed by measuring inhibition zones on agar plates and determining the minimum inhibitory concentration (MIC) through UV-vis spectrophotometry. The 100% ethanolic extract demonstrated significant inhibitory effects, with a mean inhibition zone of 14.6 mm against MRSA, outperforming the 5% (p = 0.0004) and 10% (p = 0.0402) concentrations. For S. pyogenes, the 100% extract produced the largest inhibition zone (24 mm), showing superior activity compared to the 5% (p = 0.0005) and 10% (p = 0.0485) concentrations. MIC analysis indicated optimal antimicrobial activity at both 50% and 100% concentrations for the two pathogens. These findings underscore the potential of rambutan leaf extract as a natural antimicrobial agent against resistant Gram-positive bacteria, warranting further investigation into its bioactive compounds and mechanisms of action.
The Relationship Between Cotton Bud Use and The Incidence of Cerumen Impaction Among Patients at The ENT Polyclinic of PKU Muhammadiyah Bantul Hospital Nadila; Firmansyah, Rizky; Ariani, Rizka
Ahmad Dahlan Medical Journal Vol. 6 No. 1 (2025): May 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/admj.v6i1.12624

Abstract

Cotton buds are commonly used to clean ears, although improper use can be harmful to ear health by causing cerumen impaction. Cerumen is a natural substance that normally exits the ear canal on its own but can accumulate due to cotton bud use, leading to hearing problems. This study aims to examine the relationship between cotton bud use and the incidence of cerumen impaction in patients at the ENT Polyclinic of PKU Muhammadiyah Hospital, Bantul, considering the high prevalence of this condition in Indonesia. This research used a cross-sectional design and collected data through questionnaires from 65 patients at the ENT clinic. The data were analyzed using SPSS 25 with chi-square and Fisher’s exact tests. Results showed that 86.2% of patients used cotton buds up to 2/3 of the inner ear canal. There was no significant relationship between the depth of cotton bud use and the incidence of cerumen impaction (p = 0.483). However, there was a significant relationship between the frequency of cotton bud use (> 1 time a week) and cerumen impaction in both ears (p = 0.032). Patients who frequently used cotton buds had a higher incidence of cerumen impaction compared to those who used them rarely. In conclusion, there is a relationship between the frequency of cotton bud use and the incidence of cerumen impaction.
THE ASSOCIATION OF INTERLEUKIN-6 AND PROCALCITONIN LEVELS WITH CLINICAL OUTCOME OF COVID-19 DISEASE Ramadhani, Renata Evelyn; Solikhah, Amanatus; Ariani, Rizka
Biomedika Vol 17, No 1 (2025): Biomedika August 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v17i2.12261

Abstract

Severe and potentially fatal complications can arise from COVID-19, especially when the immune system triggers an exaggerated inflammatory reaction. This study examines the possible relationship between serum levels of Interleukin-6, Procalcitonin and clinical outcomes in hospitalized COVID-19 patients. Using a retrospective cross-sectional design, this study evaluated data from 71 patients hospitalized at RSUD Wates in 2021. Biomarker level differences between survivors and non-survivors were assessed using the Mann-Whitney U test and binary logistic regression. IL-6 concentrations were significantly higher in non-surviving patients and continued to serve as an independent predictor of mortality after adjustment. Conversely, while PCT levels were higher in non-survivors, they did not retain independent prognostic significance in multivariate analysis. IL-6 is crucial in forecasting severe outcomes, likely because of its role in cytokine storms and immune dysregulation. Initial IL-6 measurement may help detect patients at higher risk and support decisions regarding intensive care. Meanwhile, raised PCT levels require careful interpretation within the broader clinical picture. Additional research involving larger sample sizes and robust methodologies is required to determine the value of combined biomarkers in COVID-19 risk evaluation.
Co-Authors Aristiani, Windy Awisarita, Wiwara Budi Rahayu, Ana Dewi, Beti E Dwi Rizkita, Leonny Festiyed Muhammad Farid Nadila Nisa, Afifah Khoiru Prisilla, Elvina Putri, Ratna Aprillia Eka Ramadhani, Renata Evelyn Ramadhania, Widya Aryana Rastrani, Ardestya Rizkita, Leonny Dwi Rizky Firmansyah Solikhah, Amanatus Sudiro, Tjahjani M Sukirto, Novi Umam Kurniawan, Nurcholid Yuniasih, Dewi