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All Journal Jurnal Riset Kefarmasian Indonesia JPK: Jurnal Proteksi Kesehatan Indonesia Berdaya Science And Education Journal (SNEJ) Medical-Surgical Journal of Nursing Research Jurnal Farmasi Ma Chung: Sains, Teknologi, dan Klinis Komunitas Pharmacon: Jurnal Farmasi Indonesia Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Mardhiyani, Dini
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Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : JPK: Jurnal Proteksi Kesehatan

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Formulation and Characterization of Nanoemulsion Turmeric oil Hendrika, Yan; Aulia, Zulikho; Mardhiyani, Dini
JURNAL PROTEKSI KESEHATAN Vol 12 No 2 (2023): JPK: Jurnal Proteksi Kesehatan
Publisher : Poltekkes Kemenkes Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36929/jpk.v12i2.733

Abstract

Turmeric oil is an essential oil derived from turmeric (Curcuma domestica). Turmeric oil is known to have antiinflammatory, antibacterial, antifungal and antioxidant activities. Nanoemulsions have the advantage of improving drug absorption and bioavailability. The purpose of the formulation of this nanoemulsion is to know the characteristics of turmeric oil nanomulsions. The formula consists of F1 (5%), F2 (10%), and F3 (15%). The preparation assessment covers organoleptic, pH, viscosity, stability, particle size, and zeta potential. The nanoemulsion preparation is produced in a thick yellow, typical odor of turmeric oil, with a pH of 6.8-7, a viskosity of 23-29 Cps, transmission values of 43.3-74.6%, droplet sizes at F1, F2, F3 of 23.2 nm, 203.8 nm, and 298.7 nm and zeta values potentials F1, F2 - 18.5mV, F 2 - 13.4mv, and F3 -8,5mV, all of the formulas well physically stable by the cracking, sedimentation and tubidity.
Antioxidant Activity Assay of Black Turmeric (C. Caesia) Water and Ethanol Extracted Using DPPH Kartini, Sri; Susanti, Pratiwi; Marshanda, Isty Maulia; Pratiwi, Denia; Mardhiyani, Dini; Hendrika, Yan
JURNAL PROTEKSI KESEHATAN Vol 12 No 2 (2023): JPK: Jurnal Proteksi Kesehatan
Publisher : Poltekkes Kemenkes Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36929/jpk.v12i2.790

Abstract

Antioxidants are compounds that provide electrons; they function by donating an electron to oxidizing compounds, thereby inhibiting the activity of these oxidants. The objective of this study is to ascertain the presence of secondary metabolites and evaluate the antioxidant properties of water and methanol extracts obtained from black turmeric (C. caesia). The determination of antioxidant activity was conducted using the DPPH method with a microplate reader at a wavelength of 520 nm, by calculating the IC50 value. The research findings indicate that both water and methanol extracts contain flavonoids, saponins, and tannins. The antioxidant activity of the water extract measured at 392.47 ± 46.38 ppm (weaker), the methanol extract displayed a higher activity at 69.66 ± 2.91 ppm (strong), and Vitamin C exhibited very strong activity at 3.98 ± 0.26 ppm.
Co-Authors Alfin Surya Anggraini, Lovera Aswatul Ulya Aulia, Zulikho Eni Yanti Wulan Desri Fitri Andriani Gendis Purno Yudanti Hendrika, Yan Irma, Dinda Aulia Islami, Deri Isna Wardaniati Kony Putriani Marshanda, Isty Maulia Mursyida, Eliya Muslim Suardi Nasution, Azlaini Yus Pratiwi, Denia Putriani, Kony Sri Kartini, Sri Susanti, Lasiah Susanti, Pratiwi vonny kurnia utama Wardaniati, Isna Wati, Huda Marlina