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All Journal Jurnal Biogenerasi Jurnal Riset Kefarmasian Indonesia JPK: Jurnal Proteksi Kesehatan Jurnal Pengabdian Masyarakat : Pemberdayaan, Inovasi dan Perubahan Jurnal Inkofar Jurnal Pengabdian Inovasi dan Teknologi Kepada Masyarakat Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE Innovative: Journal Of Social Science Research JIKA SEGANTANG LADA : JURNAL PENGABDIAN KESEHATAN Jurnal Sains dan Kesehatan
Putriani, Kony
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UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN PETAI CINA (Laucaena leucocephala (Lam.) de Wit ) TERHADAP BAKTERI Staphylococcus epidermidis DAN Salmonella typhi Putriani, Kony; Nur Aisyah, Dewi; Wardaniati, Isna
Jurnal Biogenerasi Vol. 10 No. 1 (2024): Volume 10 Nomor 1, Agustus 2024 - Februari 2025
Publisher : Universitas Cokroaminoto Palopo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30605/biogenerasi.v10i1.4917

Abstract

Di Indonesia penyakit infeksi masih menjadi masalah serius sampai saat ini dan pentingnya titingkatkan sumber obat antibakteri lain dari bahan alam, salah satunya yaitu Daun Petai Cina (Laucaena leucocephala (Lam.) de Wit ). Senyawa metabolit sekunder yang terkandung pada daun petai cina diketahui dapat menghambat pertumbuhan bakteri. Penelitian ini bertujuan untuk mengetahui kandungan senyawa metabolit sekunder yang terdapat pada daun petai cina dan mengetahui diameter daya hambat ekstrak etanol daun petai cina terhadap bakteri Staphylococcus epidermidis dan Salmonella typhi. Jenis penelitian ini yaitu eksperimental yang dilakukan dilaboratorium dengan metode ekstraksi secara maserasi menggunakan pelarut 96% dan uji antibakteri menggunakan metode cakram dengan variasi konsentrasi 100%, 50%, 25%, dan 10% serta antibiotik tetrasiklin sebagai kontrol positif dan larutan DMSO sebagai kontrol negatif. Hasil penelitian menunjukan ekstrak etanol daun petai cina mengandung senyawa metabolit sekunder flavonoid, fenolik, saponin, tannin dan steroid. Hasil dari pengujian aktivitas antibakteri ekstrak etanol daun petai cina menunjukan adanya zona hambat terhadap bakteri Staphylococcus epidermidis dengan rata-rata diameter zona hambat terbesar pada konsentrasi 100% sebesar 10,21 mm dengan kategori kuat dan pada bakteri Salmonella typhi tidak adanya zona hambat. Berdasarkan hasil penelitian ini dapat disimpulkan bahwa ekstrak etanol daun petai cina memiliki kemampuan dalam menghambat pertumuhan bakteri Staphylococcus epidermidis pada konsentrasi 100% sebesar 10,21 mm, konsentrasi 50% sebesar 8,88 mm, konsentrasi 25% sebesar 7,26 mm, dan konsentrasi 10% sebesar 6,93 mm.
Kadar Fenolik Total dan Uji Aktivitas Antioksidan Ekstrak Kulit Batang Matoa (Pometia pinnata J.R.Forst. & G. Forst) dengan DPPH Islami, Deri; Setiawati, Yuyun; Putriani, Kony
JURNAL PROTEKSI KESEHATAN Vol 14 No 2 (2025): JPK: Jurnal Proteksi Kesehatan
Publisher : Poltekkes Kemenkes Riau

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Abstract

Matoa bark (Pometia pinnata J.R. Forst. & G. Forst) has long been used traditionally as a remedy for various ailments such as fever, skin disorders, infections, and inflammation. This study aims to determine the total phenolic content and antioxidant activity of matoa bark extract obtained through successive maceration using n-hexane, ethyl acetate, and 96% ethanol. Phytochemical screening revealed the presence of alkaloids, flavonoids, tannins, saponins, and triterpenoids. The results showed that the 96% ethanol extract had the highest total phenolic content at 169.804 mg GAE/g, followed by the ethyl acetate extract at 97.647 mg GAE/g, and the n-hexane extract at 52.549 mg GAE/g. Antioxidant activity tested using the DPPH method indicated that the ethanol extract exhibited the strongest activity with an IC₅₀ value of 92.593 μg/mL (strong category), followed by the ethyl acetate extract at 121.695 μg/mL (moderate category), and the n-hexane extract at 187.393 μg/mL (weak category). This study shows the role of polar solvents in increasing antioxidant activity and total phenolic content.
EVALUASI SEDIAAN MASKER GEL PEEL-OFF KOMBINASI EKSTRAK DAUN MANGGA BACANG (Mangifera foetida)DAN DAUN SALAM (Syzygium polyanthum) Putriani, Kony; Mardhiyani, Dini; Anggraini, Lovera
Jurnal Riset Kefarmasian Indonesia Vol. 4 No. 1 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i1.218

Abstract

Mango Bacang leaves and bay leaves are plants that can be used as ingredients in traditional medicine as natural antibacterials which are believed to help get rid of acne. Several previous studies also reported that Bacang mango leaves and bay leaves have activity against Staphylococcus aureus, Escherichia coli and Salmonella typhi bacteria. This study aims to determine the evaluation results of peel-off gel mask preparations that meet the requirements. The test methods include organoleptic test, pH test, viscosity, homogeneity test and dispersion test. The test results showed that F1 and F2 were the best formulas with the characteristics of a green-black gel, a characteristic odor of mango Bacang and bay leaves, a viscosity of 1129 cPs and 1135 cPs, pH 4.4 and 4.5. The dispersion test was 5.1 cm and 5.7 cm and the homogeneity test on the peel off gel mask was homogeneous, there were no fibers, lumps or differences in color when applied to a transparent slide.
Co-Authors Andini, Febria Anggraini, Lovera Anita , Fenny Apriliani, Oksi Asiska Permata Dewi Brilian Dini Ma. Iballa Faroliu, Goldha Fernenda, Larysa FIKRI HAIKAL Fricilia, Fitri Cindy Islami, Deri Jannah , Mardiatul Komala sari, Komala Mardhiyani, Dini Nirnasari, Meily Nur Aisyah, Dewi Putri, Angelina Rahayu, Yessi Rahma Tri Cahyaningrum , Nanda Roswatidi, Eva Sativa , Oriza Serawaidi, Nadya Putri Aulya Setiawati, Yuyun Shufyani, Fahma Sidoretno, Wahyu Margi Sugara, Bayu Utama, Vonny Kurnia Wahyu Ramadhan Wardaniati, Isna