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All Journal e-GIGI JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) Padjadjaran Journal of Dentistry Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Kesehatan Manarang Syntax Idea SCIENCE : Jurnal Inovasi Pendidikan Matematika dan IPA KNOWLEDGE: Jurnal Inovasi Hasil Penelitian dan Pengembangan Buletin Kedokteran dan Kesehatan Prima
Florenly, Florenly
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EFEKTIVITAS PEMBERIAN GEL EKSTRAK ETANOL BUAH BELIMBING WULUH (AVERRHOA BILIMBI LINN) TERHADAP PENYEMBUHAN ULKUS TRAUMATIK MUKOSA ORAL TIKUS WISTAR Sutanto, Daniel; Molek, Molek; Florenly, Florenly
Jurnal Kesehatan Manarang Vol 11 No 3 (2025): December 2025
Publisher : Politeknik Kesehatan Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33490/jkm.v11i3.2053

Abstract

Star fruit (Averrhoa bilimbi Linn.) contains flavonoids, tannins, saponins, and triterpenoids that contribute to wound healing. Flavonoids act as antioxidants, tannins reduce inflammation, saponins stimulate collagen formation, and triterpenoids support tissue regeneration. This study aimed to compare the effectiveness of 10% and 20% ethanolic extracts of belimbing wuluh in influencing superoxide dismutase (SOD) and malondialdehyde (MDA) expression as well as fibroblast count in traumatic ulcers. An in vivo experimental design with a post-test only control group was conducted on male Wistar rats for 5 days. Subjects were divided into five groups: standard control, negative control (placebo), positive control (0.1% triamcinolone acetonide), treatment I (10% gel extract), and treatment II (20% gel extract). Kruskal–Wallis analysis showed significant differences among groups (p = 0.0001) for all parameters. The Mann–Whitney post hoc test indicated significant differences between the treatment and control groups, with p = 0.002 in most comparisons. The 20% concentration resulted in higher increases in SOD expression and fibroblast numbers, and greater reductions in MDA levels compared to the 10% concentration. Therefore, the ethanolic gel extract of belimbing wuluh is effective as an antioxidant in promoting the healing of traumatic ulcers, particularly through the activity of flavonoids as free radical scavengers and stimulators of fibroblast proliferation.
Oral health knowledge and its correlation to caries experience among students Zaharani, Cut Asy Syifa; Molek, Molek; Wijaya, Cindy Denhara; Florenly, Florenly; Susanto, Chandra; Tarigan, Susiani; Putra, Kriswandy; Karen, Yulia
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 2 (2025): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i2.7723

Abstract

Dental caries remains a significant global public health issue, particularly among school-aged children. A lack of knowledge regarding oral health maintenance is considered a primary contributing factor to the high prevalence and severity of caries in this demographic. This study aimed to analyze the influence of oral health maintenance knowledge on the severity of dental caries in Grade 6 students at SDN No. 060833. An analytical observational study with a cross-sectional design was conducted. A total of 39 students were selected using simple random sampling. Data on knowledge were collected using a validated questionnaire, while caries severity was assessed through direct oral examination and categorized as pit fissure caries, superficial caries, medium caries, or profound caries. Data analysis employed univariate and bivariate methods using the Chi-Square test. The majority of students (64.1%) had poor knowledge of oral health maintenance. The most common caries severity was superficial caries (35.9%), followed by medium caries (30.8%). Bivariate analysis revealed a statistically significant relationship between knowledge level and caries severity (p-value = 0.000). Students with poor knowledge were more likely to experience medium and profound caries. There is a significant influence of the level of knowledge about oral health maintenance on the severity of dental caries in Grade 6 students. Efforts to improve oral health knowledge through targeted education programs in schools are essential to prevent and reduce the severity of dental caries.
Antimicrobial Potential of Ethanol Extract from Avocado Seeds (persea americana mill.) on The Healing of Socket Wounds from Tooth Extraction in Male Wistar Rat Halim, Susanna; Florenly, Florenly; Gustian, Rayvan Juan
Jurnal Penelitian Pendidikan IPA Vol 12 No 2 (2026): In Progress
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v12i2.14458

Abstract

Healing of tooth socket wounds after tooth extraction is a complex process involving phases of inflammation, proliferation, and tissue remodeling. Avocado seeds (Persea Americana Mill.) are known to contain bioactive compounds, including flavonoids, saponins, tannins, and triterpenoids, which have the ability to accelerate the wound healing process. This study aims to determine the effectiveness of avocado seed ethanol extract gel on changes in body weight, socket wound diameter, and socket depth after tooth extraction. This study used a laboratory experimental design with a post-test only control group design using male Wistar rats as test animals. The samples were divided into five groups, consisting of a negative control, a positive control (Gengigel), and treatment groups with avocado seed ethanol extract gel at concentrations of 10%, 20%, and 30%. Body weight was measured from day 1 to day 14. The diameter and depth of the socket wound were also measured periodically. Data analysis used the Paired Samples T-Test, Welch ANOVA, and Dunnett T3 Posthoc test in accordance with the results of normality using the Shapiro-Wilk test and data homogeneity using the Levene test. Based on the results of the study, it was found that 10% ethanol extract gel from avocado seeds was most effective in maintaining the stability of the body weight parameters of the test animals, and 30% ethanol extract gel from avocado seeds was most effective in accelerating the reduction in wound diameter and depth, with results comparable to the gold standard (Gengigel). It can be concluded that ethanol extract gel from avocado seeds, especially at a concentration of 30%, is effective in accelerating the healing process of socket wounds after tooth extraction.
Co-Authors Anh Thu, Pham Ngoc Bao, Nguyen P. G. Daniel Sutanto, Daniel Dung, Pham C. T. Friando, Jovin Gustian, Rayvan Juan Halim, Susanna Harahape, Fitriah Khairani Huy, Nguyen Quang Ivanka, Ivanka Karen, Yulia Kelvin Kelvin Khosasi, Winda Le, Hong Hai Leslie, Gloria Estefani Lokanata, Shieny Lukita, Shavilla Luman, Marco Luzria, Cut Cynthia Mai, Phuong Thao Molek, Molek Nauli, Helen Theresia Ngo Viet Nhan, Ngo Viet Nhan Nhan, Ngo Viet Nicoline, Felice Florencia Oktavia, Yuli Pratama, Rizky Putra, Kriswandy Samantha, Samantha Sim, Mellisa Sintapanont, Anusak Siregar, Ariska Putri Susanto, Chandra Tandry, Elshendro Tandrya, Elshendro Tarigan, Gabriel C.J. Tarigan, Susiani Trang, Tran Nhut Thao Wijaya, Cindy D. Wijaya, Cindy Denhara Winata, Mellisa Zaharani, Cut Asy Syifa