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Influence Zalak Fruit Skin Extract (Salacca zalacca) On Lipid Profiles in Type 2 Diabetes Mice Suntara, Ditte Ayu; Hutapea, Albert M; Napiah, Ali; Halim, Susanna
Nusantara Science and Technology Proceedings The 1st International Conference of Health Institut Kesehatan Mitra Bunda 2024
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2024.4312

Abstract

Salak peel was found to contain various phytochemical substances, including saponins, alkaloids, flavonoids, steroids, and phenolics. There is a common belief that certain active chemicals have antioxidant properties and have the potential to reduce glucose levels in the human body (Sandhar et al., 2011). Objective study For investigate the impact skin snake fruit on lipid profile, on T2DM mice. Study laboratory experimental, with quasi-experimental, in a manner special use Pretest-Posttest design. Group Experiment: 15 mice Wistar male, which is divided become three group. Group 1 works as negative control (TP), group 2 involved metformin (M) administration, focus group 3 on delivery extract skin Salak (EKS). Treatment given for 3 weeks, obtained results happen change average lipid profile in each point measuring Where change No significant increase or decrease on TP, M, EKS groups, with p?0.05. Regeneration of pancreatic beta cells No influenced by presence metabolites secondary, including flavonoids, phenolics, and saponin, in extract ethanol skin snake fruit. And no can hinder conversion superoxide become hydrogen superoxide through the transformation chain. Besides that, flavonoids facilitate Power pull radical free to the hydrogen atom from group hydroxyl aromatic, so No help in a way significant in elimination they from body through system deletion.
THE UNPLEASANT TRUTH: EXPLORING THE COMPLEXITIES OF HALITOSIS Kartika, Henny; Chuan, How Kim; Halim, Susanna
SCIENCE : Jurnal Inovasi Pendidikan Matematika dan IPA Vol. 5 No. 2 (2025)
Publisher : Pusat Pengembangan Pendidikan dan Penelitian Indonesia (P4I)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51878/science.v5i2.4879

Abstract

Halitosis, or bad breath, is a common condition that can significantly affect an individual’s quality of life and social interactions. It results from a complex interaction of multiple etiological factors, predominantly originating within the oral cavity such as the activity of anaerobic microbes producing volatile sulfur compounds (VSCs), but also greatly influenced by systemic health status, diet, and lifestyle choices. Effective management therefore requires a comprehensive and careful diagnostic approach, not only to identify specific etiological factors such as the level of oral hygiene, periodontal health, and the presence or absence of xerostomia, but also to uncover potential contributions from underlying systemic medical conditions and dietary intake. This paper aims to present a comprehensive review of current concepts in the diagnosis and management of halitosis. Successful halitosis management strategies rely heavily on the pillars of ongoing patient education, the development of a personalized treatment plan based on the underlying cause—including mechanical and chemical interventions—and regular clinical monitoring and follow-up. Furthermore, interdisciplinary collaboration, combining expertise from dentistry, oral microbiology, internal medicine, and psychology, is crucial to advance more accurate diagnostic approaches and more effective therapeutic options. Thus, the importance of implementing a holistic, interdisciplinary, patient-centered approach to improve overall oral health and enhance overall patient well-being is emphasized. ABSTRAKHalitosis, atau bau mulut, adalah kondisi umum yang dapat memengaruhi kualitas hidup dan interaksi sosial seseorang secara signifikan. Hal ini disebabkan oleh interaksi kompleks berbagai faktor etiologi, yang sebagian besar berasal dari rongga mulut seperti aktivitas mikroba anaerobik yang menghasilkan senyawa sulfur volatil (VSC), tetapi juga sangat dipengaruhi oleh status kesehatan sistemik, pola makan, dan pilihan gaya hidup. Oleh karena itu, penanganan yang efektif memerlukan pendekatan diagnostik yang komprehensif dan cermat, tidak hanya untuk mengidentifikasi faktor etiologi tertentu seperti tingkat kebersihan mulut, kesehatan periodontal, dan ada atau tidaknya xerostomia, tetapi juga untuk mengungkap potensi kontribusi dari kondisi medis sistemik yang mendasarinya dan asupan makanan. artikel ini bertujuan untuk menyajikan tinjauan komprehensif tentang konsep terkini dalam diagnosis dan penanganan halitosis. Strategi penanganan halitosis yang berhasil sangat bergantung pada pilar-pilar edukasi pasien yang berkelanjutan, pengembangan rencana perawatan yang dipersonalisasi berdasarkan penyebab yang mendasarinya termasuk intervensi mekanis dan kimia dan pemantauan dan tindak lanjut klinis yang teratur. Lebih jauh lagi, kolaborasi interdisipliner, yang menggabungkan keahlian dari kedokteran gigi, mikrobiologi oral, penyakit dalam, dan psikologi, sangat penting untuk memajukan pendekatan diagnostik yang lebih akurat dan pilihan terapi yang lebih efektif. Dengan demikian, pentingnya menerapkan pendekatan holistik, interdisipliner, dan berpusat pada pasien untuk meningkatkan kesehatan mulut secara keseluruhan dan meningkatkan kesejahteraan pasien secara keseluruhan ditekankan.
THE PATHOPHYSIOLOGY AND MANAGEMENT OF XEROSTOMIA: A COMPREHENSIVE REVIEW Raja, Ricky Ferdian; Chuan, How Kim; Halim, Susanna
SCIENCE : Jurnal Inovasi Pendidikan Matematika dan IPA Vol. 5 No. 2 (2025)
Publisher : Pusat Pengembangan Pendidikan dan Penelitian Indonesia (P4I)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51878/science.v5i2.4880

Abstract

ABSTRACT Xerostomia, or more commonly known as dry mouth, is a common clinical condition that significantly affects oral comfort and health, characterized not only by the subjective sensation of dryness in the oral cavity but also by an objective decrease in the measured function of the salivary glands. Its etiology is multifactorial, often related to the side effects of more than hundreds of types of drugs, the consequences of radiotherapy to the head and neck area, manifestations of systemic diseases such as Sjögren's Syndrome and diabetes, and the natural aging process. This decrease in the quantity and quality of saliva directly interferes with the natural defense mechanisms of the mouth, increasing the risk of rampant dental caries, opportunistic infections such as oral candidiasis, and causing significant difficulties in mastication, deglutition and phonation, which ultimately negatively impact the quality of life of the sufferer. Therefore, effective management of xerostomia requires a comprehensive multidisciplinary approach, starting from an accurate diagnosis through anamnesis, clinical examination and sialometry, to the implementation of a treatment strategy tailored to the cause and severity, and ongoing patient education. This comprehensive perspective article aims to provide an in-depth review of the etiology, diagnostic approaches, and current spectrum of xerostomia management, highlighting recent advances in therapeutic modalities including salivary stimulants, artificial saliva, and mucosal protective agents as well as strategies for the prevention of oral complications. Particular attention is paid to the importance of an interdisciplinary perspective, emphasizing the vital role of collaboration between dentists, general practitioners/specialists, and pharmacists in developing a holistic and integrated patient care plan to improve the oral health and quality of life of individuals affected by xerostomia. ABSTRAKXerostomia, atau yang lebih dikenal dengan sebutan mulut kering, merupakan kondisi klinis umum yang secara signifikan memengaruhi kenyamanan dan kesehatan mulut, ditandai tidak hanya oleh sensasi subjektif kekeringan di rongga mulut tetapi juga oleh penurunan objektif fungsi kelenjar ludah yang terukur. Etiologinya multifaktorial, sering kali terkait dengan efek samping dari lebih dari ratusan jenis obat, konsekuensi radioterapi pada area kepala dan leher, manifestasi penyakit sistemik seperti Sindrom Sjögren dan diabetes, serta proses penuaan alami. Penurunan kuantitas dan kualitas air liur ini secara langsung mengganggu mekanisme pertahanan alami mulut, meningkatkan risiko karies gigi yang merajalela, infeksi oportunistik seperti kandidiasis oral, dan menyebabkan kesulitan yang signifikan dalam mengunyah, menelan, dan bersuara, yang pada akhirnya berdampak negatif pada kualitas hidup penderitanya. Oleh karena itu, penanganan xerostomia yang efektif memerlukan pendekatan multidisiplin yang komprehensif, mulai dari diagnosis yang akurat melalui anamnesis, pemeriksaan klinis dan sialometri, hingga penerapan strategi pengobatan yang disesuaikan dengan penyebab dan tingkat keparahan, serta edukasi pasien yang berkelanjutan. Artikel perspektif yang komprehensif ini bertujuan untuk memberikan tinjauan mendalam tentang etiologi, pendekatan diagnostik, dan spektrum penanganan xerostomia saat ini, yang menyoroti kemajuan terkini dalam modalitas terapi termasuk stimulan saliva, saliva buatan, dan agen pelindung mukosa serta strategi untuk pencegahan komplikasi oral. Perhatian khusus diberikan pada pentingnya perspektif interdisipliner, yang menekankan peran penting kolaborasi antara dokter gigi, dokter umum/spesialis, dan apoteker dalam mengembangkan rencana perawatan pasien yang holistik dan terintegrasi untuk meningkatkan kesehatan mulut dan kualitas hidup individu yang terkena xerostomia.  
Oral mucosal lesions associated with fixed orthodontic appliances: A review Kawono, Kawono; Chuan, How Kim; Halim, Susanna
Jurnal Prima Medika Sains Vol. 7 No. 1 (2025): June
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v7i1.6764

Abstract

Orthodontic procedures enhance dental well-being, yet they can lead to painful sores due to irritation from devices. These sores, often found on the inner cheeks and lips, arise from friction caused by brackets, wires, and screws, resulting in discomfort and slow recovery. To prevent these issues, one can use orthodontic wax, materials that are friendly to the body, and make adjustments to the appliances. Innovative treatments like low-level laser therapy and personalized 3D-printed devices are proving to be promising options for relief. Regular check-ups and working together as a team are essential for providing effective care. Addressing issues early can lessen complications, boost comfort, and improve results of orthodontic care, emphasizing the importance of both preventive and treatment methods in practice.
The two way relationship between diabetes mellitus and periodontal disease Ongko, Darius Pranajaya; Chuan, How Kim; Halim, Susanna
Jurnal Prima Medika Sains Vol. 7 No. 1 (2025): June
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v7i1.6765

Abstract

Periodontitis and diabetes mellitus are common chronic diseases with an established bidirectional relationships. Epidemiological studies have clearly identified that diabetes is a major factor for periodontitis, increasing the risk approximately three-fold compared to non-diabetic individuals, particularly if glycemic control is poor. This article discusses the possibility impact of diabetes on the periodontal patient and the ways in which untreated periodontitis may influence the course of diabetes. Diabetes mellitus is considered a risk factor and associated with an increased prevalence and severity of gingivitis and periodontitis. Inflammation plays an obvious role in periodontal diseases, evidence in literature also supports the role of inflammation as a major component in the pathogenesis of diabetes and diabetes complications. There is also evidence that periodontal disease can worsen a patient’s control of diabetes mellitus and proper management of periodontal disease can improve control of diabetes mellitus. The association between diabetes mellitus and periodontal diseases is clear that glycemic control improves periodontal conditions, while the management of periodontal infection improves glycemic control of diabetic patients (HbA1c reduction approximately 0,4%). Periodontal assessment is as important in people with diabetes as it is in people who do not have diabetes and people with diabetes should be made aware of their increased risk for periodontal disease.
Analysis of Electronic Medical Records Data Security: Case Study in Citra Husada Sigli Hospital Juliana, Juliana; Alamsyah, Alamsyah; Halim, Susanna
Jurnal Penelitian Pendidikan IPA Vol 11 No 6 (2025): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i6.11081

Abstract

In health services, electronic medical record (E-MR) stands as tool to accelerate the provision of services to patients. However, patient’s medical record data must be kept secure, especially because it is easily hacked by unauthorized parties. This study aims to analyze the security of E-MR data at Citra Husada Hospital and identify risks that can occur. This study uses a qualitative survey with a case study design with 10 respondents that were selected by purposive sampling. The aspects of patient’s E-MR data security studied were confidentiality, integrity, authentication, availability, access control and non-repudiation. The security of E-RM data is generally good in confidentiality, authentication, availability, access control, and non-repudiation. However, some areas need improvement. While login requires a username and password, the password complexity is weak. Integrity is inadequate due to the lack of an SOP for data changes. Authentication includes digital signature related to encrypted username and password but lacks a certified electronic signature. The system is accessible only within the hospital’s intranet, ensuring availability. Access rights are well-structured. A track record ensures non-repudiation. The highest risk is unauthorized changes to patient data, highlighting the need for stronger risk management measures.
ARTIKEL REVIEW: DENTAL IMPLANT Halim, Susanna; Florenly, Florenly; Tarigan, Gabriel C.J.; Pratama, Rizky
KNOWLEDGE: Jurnal Inovasi Hasil Penelitian dan Pengembangan Vol. 5 No. 2 (2025)
Publisher : Pusat Pengembangan Pendidikan dan Penelitian Indonesia (P4I)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51878/knowledge.v5i2.6533

Abstract

Dental implants as a solution for tooth loss rehabilitation are increasingly developing with various approaches and techniques tailored to the clinical needs of each patient. This review article aims to summarize and analyze two recent studies on dental implants, namely the Guided Bone Regeneration (GBR) technique, and factors affecting marginal bone loss in implants. This study adopted a literature review method with a focus on case report articles related to dental implants. Data were collected from articles published over the past ten years through the Google Scholar database. The first article explored the use of GBR technique for bone augmentation in patients with mandibular bone volume deficiency. This method was shown to be effective in increasing bone volume and implant stability through the use of xenograft bone graft. The second article identifies various factors that contribute to marginal bone loss in the early postimplant stage. The analysis showed that abutment selection and retention need to consider implant positioning, aesthetics, and ease of long-term maintenance. The GBR technique has been shown to be effective in increasing the bone volume that supports implant stability, although its application still requires long-term evaluation. In addition, marginal bone loss is caused by multifactorial factors such as bone quality and the surgical technique used. Selection of the right method and an in-depth understanding of the patient's clinical condition are essential for successful dental implant therapy. ABSTRAKImplan gigi sebagai solusi untuk rehabilitasi kehilangan gigi semakin berkembang dengan berbagai pendekatan dan teknik yang disesuaikan dengan kebutuhan klinis masing-masing pasien. Artikel review ini bertujuan untuk merangkum dan menganalisis dua penelitian terbaru mengenai implan gigi, yaitu teknik Guided Bone Regeneration (GBR), dan faktor apa saja yang dapat mempengaruhi penurunan tulang marginal pada implan. Penelitian ini mengadopsi metode tinjauan literatur dengan fokus pada artikel case report terkait implan gigi. Data dikumpulkan dari artikel-artikel yang diterbitkan selama kurun waktu sepuluh tahun terakhir melalui database Google Scholar. Artikel pertama mengeksplorasi penggunaan teknik GBR untuk augmentasi tulang pada pasien dengan kekurangan volume tulang mandibula. Metode ini terbukti efektif dalam meningkatkan volume tulang dan stabilitas implan melalui penggunaan bone graft xenograft. Artikel kedua mengidentifikasi berbagai faktor yang berkontribusi terhadap marginal bone loss pada tahap awal pasca pemasangan implan. Hasil analisis menunjukkan bahwa pemilihan abutment dan retensi perlu mempertimbangkan posisi implan, estetika, dan kemudahan perawatan jangka panjang. Teknik GBR terbukti efektif untuk meningkatkan volume tulang yang mendukung stabilitas implan, meskipun penerapannya masih membutuhkan evaluasi jangka panjang. Selain itu, penurunan tulang marginal disebabkan oleh faktor multifaktorial seperti kualitas tulang dan teknik bedah yang digunakan. Pemilihan metode yang tepat dan pemahaman mendalam tentang kondisi klinis pasien sangat penting untuk keberhasilan terapi implan gigi.
AGING EFFECT ON SALIVARY GLAND : A REVIEW Ongko, Felix Hartanto; How, Kim-Chuan; Halim, Susanna
CENDEKIA: Jurnal Ilmu Pengetahuan Vol. 5 No. 2 (2025)
Publisher : Pusat Pengembangan Pendidikan dan Penelitian Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51878/cendekia.v5i2.4743

Abstract

Swallowing disorders and dry mouth are the most common oral conditions faced by aging adults. Dry mouth increases the risk of dental caries, periodontal disease, candidiasis, oral ulceration, dysphagia which can have a negative impact on nutritional status and quality of life. Saliva secreted in oral cavity is essential for food ingestion and plays an important role in sensory perception. Aging affects salivary glands and changes quantity and quality of saliva. Alterations in salivary gland function can have adverse effects on oral and systemic health. Salivary hypofunction is associated with decreased chewing and swallowing ability as well as objective taste perception. Many medical conditions and drug treatments usually affect saliva through  anticholinergic  activity  in  older  adults.  Lifestyle  factors  will  also  modify  saliva gradually over time. Besides histological gland atrophy, physiological effects of aging cause changes in salivary gland function due to decreased intensity of stimulation and reflexes in elderly population. With increasing age, there is a reduction in the number of olfactory and taste receptors, decreased neuronal salivary stimulation and decreased blood perfusion at the gland level. Complex relationship between aging and salivary changes have variability results in elderly subjects and still need many research to point out the main problem. ABSTRAKGangguan menelandan mulut kering merupakan kondisi mulut yang palingumumdialamioleh orang dewasa yang menua. Mulut kering meningkatkan risikokaries gigi, penyakit periodontal, kandidiasis, ulserasi oral, disfagia yang dapat berdampak negatif pada status gizi dan kualitas hidup. Air liur yang disekresikan dalam rongga mulut sangat pentinguntuk menelan makanan dan berperan penting  dalam persepsi  sensorik.  Penuaan  memengaruhi  kelenjar  ludah  dan mengubah kuantitas dan kualitas air liur. Perubahan fungsi kelenjar ludah dapat berdampak buruk pada kesehatan mulut dan  sistemik.  Hipofungsi  saliva  dikaitkan  dengan penurunan kemampuan mengunyah dan menelan serta persepsi rasa objektif. Banyak kondisi medis dan perawatan obat biasanya memengaruhi air liur melalui aktivitas antikolinergik pada orang dewasa yang lebih tua. Faktor gaya hidup juga akan mengubah air liur secara bertahap seiring berjalannya waktu.  Selain  atrofi kelenjar histologis, efek fisiologis penuaan menyebabkan perubahan fungsi kelenjar ludah karena penurunan intensitas rangsangan dan refleks pada populasi lanjutusia. Dengan bertambahnyausia, terjadi penurunan jumlahreseptor penciuman dan pengecap, penurunan rangsangan sarafterhadap air liur, dan penurunan perfusi darah di tingkat kelenjar. Hubungan yang kompleks antara penuaan dan perubahan saliva memiliki hasil yang bervariasi  pada  subjek  lanjut  usia  dan  masih  memerlukan  banyak  penelitian  untuk menunjukkan masalah utamanya.
TINJAUAN ARTIKEL PENGARUH DIABETES MELLITUS TERHADAP KEBERHASILAN DAN STABILITAS IMPLANT GIGI Halim, Susanna; Susanto, Susanto; Arianto, Muhammad Wandy; Al-Furqa’an, Muhammad; Pang, Vincent
CENDEKIA: Jurnal Ilmu Pengetahuan Vol. 5 No. 3 (2025)
Publisher : Pusat Pengembangan Pendidikan dan Penelitian Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51878/cendekia.v5i3.6436

Abstract

Dental implants are the latest and most effective restorative solution for replacing missing teeth. However, their success rate can be significantly affected by the patient's systemic conditions, particularly diabetes mellitus, which can inhibit bone osseointegration if blood glucose levels are uncontrolled. This background encourages the need for in-depth investigation of strategies to improve implant survival in this at-risk population. This study, structured as a literature review, specifically focuses on analyzing methods and techniques that can optimize the success of dental implants in people with diabetes. The research phase involved a systematic review of scientific articles from the PubMed and Google Scholar databases published between 2019 and 2024, analyzing cases of diabetic patients who received immediate post-extraction implant treatment. The main findings indicate that good osseointegration can be achieved through the technique of placing implants directly into the new extraction socket, particularly in the anterior mandible. This success is significantly supported by the use of advanced regenerative materials, such as the combination of freeze-dried bone allograft (FDBA) with injectable platelet-rich fibrin (i-PRF), which has been shown to effectively stimulate bone and periodontal tissue regeneration even in cases of aggressive periodontitis. Furthermore, the use of longer implants, a collagen membrane in the posterior area, and supportive protocols such as prophylactic antibiotics and 0.12% chlorhexidine mouthwash play a significant role in minimizing the risk of inflammation. In conclusion, although diabetic patients have a higher risk of implant failure, the application of appropriate and personalized treatment methods—including surgical techniques, regenerative materials, and long-term maintenance—can achieve very high success rates of up to 97.6%. These results underscore the importance of comprehensive individualized treatment planning and careful evaluation of the patient's systemic condition to ensure the long-term success of implant restorations. ABSTRAKImplan gigi merupakan solusi restoratif terkini dan paling efektif untuk menggantikan gigi yang hilang, namun tingkat keberhasilannya dapat sangat dipengaruhi oleh kondisi sistemik pasien, terutama diabetes mellitus, yang dapat menghambat proses osseointegrasi tulang jika kadar glukosa darah tidak terkendali. Latar belakang ini mendorong perlunya investigasi mendalam terhadap strategi untuk meningkatkan ketahanan implan pada populasi berisiko ini. Penelitian ini, yang disusun sebagai studi literatur, secara spesifik berfokus pada analisis metode dan teknik yang dapat mengoptimalkan keberhasilan implan gigi pada penderita diabetes. Tahapan penelitian melibatkan peninjauan sistematis terhadap artikel ilmiah dari database PubMed dan Google Scholar yang dipublikasikan antara tahun 2019 hingga 2024, menganalisis kasus-kasus pasien diabetes yang menerima perawatan implan segera pasca-ekstraksi. Temuan utama menunjukkan bahwa osseointegrasi yang baik dapat dicapai melalui teknik pemasangan implan secara langsung pada soket ekstraksi baru, terutama di area anterior mandibula. Keberhasilan ini didukung secara signifikan oleh penggunaan material regeneratif canggih, seperti kombinasi freeze-dried bone allograft (FDBA) dengan injectable platelet-rich fibrin (i-PRF), yang terbukti efektif merangsang regenerasi tulang dan jaringan periodontal bahkan pada kasus periodontitis agresif. Selain itu, penggunaan implan yang lebih panjang, membran kolagen pada area posterior, serta protokol pendukung seperti pemberian antibiotik profilaksis dan obat kumur klorheksidin 0,12% turut berperan penting dalam meminimalkan risiko inflamasi. Kesimpulannya, meskipun pasien diabetes memiliki risiko kegagalan implan yang lebih tinggi, penerapan metode perawatan yang tepat dan terpersonalisasi—mencakup teknik bedah, material regeneratif, dan pemeliharaan jangka panjang—dapat mencapai tingkat keberhasilan yang sangat tinggi hingga 97,6%. Hasil ini menggarisbawahi pentingnya perencanaan perawatan individual yang komprehensif dan evaluasi kondisi sistemik pasien secara cermat untuk memastikan kesuksesan jangka panjang restorasi implan.
MANAGEMENT OF GINGIVAL ENLARGEMENT IN PATIENT WITH NON SURGICAL TREATMENT: A CASE REPORT Watri, Desi; Chuan, How Kim; Halim, Susanna
SCIENCE : Jurnal Inovasi Pendidikan Matematika dan IPA Vol. 5 No. 1 (2025)
Publisher : Pusat Pengembangan Pendidikan dan Penelitian Indonesia (P4I)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51878/science.v5i1.4748

Abstract

Penyakit gingiva merupakan peradangan pada rongga mulut dan pembengkakan gingiva merupakan salah satu hal yang paling sering ditemukan. Pembesaran gingiva merupakan lesi inflamasi kronis yang disebabkan oleh plak bakteri dan kalkulus. Pembesaran gingiva muncul pada tingkat papila interdental dan/atau jaringan marginal gingiva, dapat terlokalisasi atau menyeluruh. Artikel ini mengkaji kasus pasien yang menderita pembesaran gingiva dan lesi gingiva yang disebabkan oleh plak bakteri. Kasus ini ditangani dengan perawatan periodontal nonsurgical. Selama lima hari, dilakukan terapi antibiotik dan terapi manual. Evaluasi ulang satu bulan kemudian menunjukkan resolusi pembesaran, penurunan peradangan, supurasi, persentase poket periodontal dan penurunan pembengkakan gingiva; perawatan periodontal dilakukan pada saat itu. Setelah tiga bulan, terjadi penurunan persentase poket periodontal dan pembengkakan gingiva; pada saat itu dilakukan terapi periodontal pemeliharaan. ABSTRACTGingiva diseases is an inflammation in oral cavity and gingiva enlargement is one of the most common things found. Gingival enlargement is a chronic inflammatory lesion caused by bacterial plaque and calculus. It appears at the level of interdental papilla and/or marginal gingival tissue, it can be localized or generalized. This article studies a case of a patient who suffered from gingival enlargement and gingival lesions caused by bacterial plaque. This case was managed with the use of nonsurgical periodontal treatment. For five days, antibiotic therapy and manual therapy were performed. Re-evaluation one month later showed resolution of the enlargement, decrease in inflammation, suppuration, percentage of periodontal pockets and decrease gingival swelling; periodontal treatment was performed at that time. After three months, a decrease in the percentage of periodontal pockets and gingival swelling was observed; at that time maintenance periodontal therapy was performed.