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Analisis Molecular Docking Senyawa Garcinia Mangostana L Sebagai Kandidat Anti SARS-CoV-2 Rena, Suci Ramda; Nurhidayah, Nurhidayah; Rustan, Rustan
Jurnal Fisika Unand Vol 11 No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jfu.11.1.82-88.2022

Abstract

Penelitian ini bertujuan untuk mengetahui potensi dari senyawa-senyawa alami Garcinia mangostana L. atau kulit manggis sebagai kandidat anti-SARS-CoV-2 dengan menghambat main protease (MPro) COVID-19. Dalam penelitian ini digunakan metode molecular docking dengan program Autodock Vina dan di-visualisasi-kan dengan program Discovery Studio. Kemampuan inhibitor dinilai berdasarkan energi bebas ikatan (ΔG), Konstanta inhibisi (Ki), kompleks ligan-reseptor dan ikatan hidrogen. Validasi dilakukan dengan re-docking ligan alami X77 terhadap protein target (6W63) dengan hasil RMSD 1.082 Å. Simulasi docking dari 3 ligan uji diperoleh 1 senyawa dengan afinitas terbaik yang menghasilkan ΔG = -7.8 kcal/mol dan Ki = 1,91 µM. Berdasarkan hasil penelitian, diantara ligan uji senyawa beta-mangostin paling berpotensi sebagai kandidat anti-SARS-CoV-2 dengan afinitas terbaik.
OPTIMALISASI POTENSI LOKAL DAN KEARIFAN BUDAYA DALAM MEWUJUDKAN KEMANDIRIAN DAN KEBERLANJUTAN PEMBANGUNAN DI DESA SOKONG KECAMATAN TANJUNG KABUPATEN LOMBOK UTARA Isnawati, Isnawati; Nurjannah, Alifah Siti; Agustin, Baiq Wilmalia; Riadah, Siti; Alfisahari, Andrea; Andriansyah, Diky; Deviani, I Gusti Ayu Shirin Kartika; Hamdayani, Septya; Yani, Indri Rachma; Rustan, Rustan; Simanjuntak, Rahel Tiona Gracella
Jurnal Wicara Vol 3 No 6 (2025): Jurnal Wicara Desa
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/3gb0y743

Abstract

Sokong Village, Tanjung District, North Lombok Regency, boasts local potential, including natural resources in the livestock sector, trigona honey cultivation, and a wealth of cultural wisdom, which serve as key assets for village development. The University of Mataram's 2025 Community Service Program for Village Empowerment (KKN-PMD) implemented a series of community empowerment activities using an educational and participatory approach. Core activities included training in fermented feed and healthy livestock care to increase livestock productivity, training in trigona honey bee cultivation integrating care techniques and digital marketing, and the development of a culture-based tourism village through local wisdom mapping, cultural performances, and digital promotion training. Additionally, additional programs such as fun classes for children, nutrition education at integrated health posts (Posyandu), village administration assistance, and Independence Day celebrations have had a positive multidimensional impact. Program results demonstrated improved technical skills, the formation of independent trigona honey business groups, and an increased village appeal as a cultural tourism destination. This program has successfully promoted community economic independence and the preservation of cultural values ​​as a foundation for the sustainable development of Sokong Village.
Comparative Analysis of Fisheries Business in Selayar Regency: Reviewed From the Fundamental Aspect of Finance Lailil, Dinar; Rustan, Rustan; Badollahi, Ismail
Journal La Sociale Vol. 7 No. 1 (2026): Journal La Sociale
Publisher : Borong Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journal-la-sociale.v7i1.2508

Abstract

This study aims to analyze and compare the financial performance of two fisheries businesses in the Selayar Islands Regency, namely CV. Sinar Jaya and CV. Yabba 505, based on fundamental financial aspects including accounts receivable turnover, liquidity, quality costs, and sales during the period 2021 to 2024. The method used is a quantitative approach with descriptive analysis and trend analysis, based on financial report data and interviews. The results show that CV. Sinar Jaya has relatively stable liquidity and sales management and improved efficiency in managing accounts receivable and quality costs. Meanwhile, CV. Yabba 505 experienced significant fluctuations in liquidity and accounts receivable turnover, despite recording higher annual sales growth in percentage terms. This study emphasizes the importance of integrated management of fundamental financial aspects to improve the competitiveness and sustainability of local fisheries businesses. These findings are expected to serve as a reference for business actors and policymakers in formulating strategies for developing MSMEs in the fisheries sector in the archipelago.