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The Development of A Mini Autoclave for Bubur Ceria MPASI Products as an Alternative to Prevent Growth Retardation Faizal, Imam Agus; Nugroho, Yusuf Eko; Yunadi, Frisca Dewi
Jurnal SOLMA Vol. 12 No. 3 (2023)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v12i3.12810

Abstract

Background: Prinsip hygiene dan sanitasi makanan merupakan bentuk upaya pencegahan penyakit pada manusia. Mitra pengabdian ini yaitu “Bubur Bayi Sehat Ceria” yang sudah banyak berkontribusi dalam pencegahan stunting sebagai MPASI. Tujuan Pemberdayaan Masyarakat Pemula (PMP) pengabdian ini yaitu menginovasi pengemasan bubur dari cup plastic ke autoclavable pouch agar bubur lebih awet dan tahan lama dan menerapan teknologi berbasis mini autoklaf saat bubur dikemas agar lebih higienis dan steril terhadap patogen. Metode: Pelaksananaan PMP dimulai survei awal dan akad kerjasama mitra dengan pihak mitra kerjasama dengan Metode Focus Group Discussion (FGD). Sosialisasi materi dan Pelatihan di Audotorium dan Laboratatorium Mikrobiologi Universitas Al-Irsyad Cilacap. Evaluasi pelaksanaan dan keberlanjutan kegiatan PMP. Hasil: Terlaksana sosialisasi materi dan pelatihan pengemasan bubur ceria dengan teknologi autoclavable pouch. Sebanyak 30% setuju dan 70% memilih setuju sekali terkait penilaian kemasan dan leaflet baru bubur ceria. Kesimpulan: Pengemasan bubur dengan autoclavable pouch menjadikan bubur lebih higienis steril, dan tahan lama.
In Vitro Anti-Biofilm Activity of Nutmeg (Myristica fragrans) Leaf Infusion Extract Wijayanti, Faulia Triana; Nugroho, Yusuf Eko; Pangesti, Ira
Jurnal Laboratorium Khatulistiwa Vol 9, No 1 (2025): November 2025
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v9i1.2097

Abstract

Pseudomonas aeruginosa is an opportunistic Gram-negative bacterium commonly associated with severe infections, particularly in immunocompromised individuals. One of its major virulence factors is biofilm formation, which contributes to increased antimicrobial resistance. This study aimed to evaluate the inhibitory activity of nutmeg (Myristica fragrans) leaf infusion extract against P. aeruginosa biofilm formation in vitro. The experiment was conducted using a 96-well microtiter plate assay, and biofilm intensity was quantified at 595 nm following crystal violet staining. The results demonstrated that the nutmeg leaf infusion extract significantly inhibited biofilm formation, with varying levels of effectiveness depending on incubation time. These findings indicate the potential of nutmeg leaf infusion extract as an antibiofilm agent against P. aeruginosa.
Sensitivity of Torch Ginger and Basil Extracts Against Candida sp. from Vaginal Discharge Samples Arelliza, Fatma Sheilla; Nugroho, Yusuf Eko; Faizal, Imam Agus
Jurnal Laboratorium Khatulistiwa Vol 9, No 1 (2025): November 2025
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v9i1.2100

Abstract

Pathological vaginal discharge is a common infection among women, often caused by the fungal species Candida albicans. The increasing resistance to synthetic antifungal agents such as ketoconazole has prompted the need for alternative herbal therapies. This study aimed to identify the presence of Candida albicans in vaginal swab samples from female D4 TLM UNAIC students an to assess the antifungal activity of combined extracts of kecombrang flower (Etlingera elatior) and basil leaves (Ocimum basilicum) prepared using the infusion method. An experimental design was used with the well diffusion method to measure inhibition zones at extract concentration of 50%, 70%, and 90%. The results showed that 31% of the 48 samples tested positive for Candida albicans. Macroscopically, the colonies appeared white to cream, convex, and had a characteristic yeast odor, while microscopic examination revealed blastospores. The positive control group using ketoconazole exhibited strong antifungal activity with an inhibition zone diameter of 23 mm. In contrast, the combined infusion extracts at all tested concentration (50%, 70%, and 90%) showed no inhibition zones (0 mm), indicating an absence of antifungal activity. The conclusions of this research are the infusion extraction method was ineffective in isolating active antifungal compounds from the tested plants under the conditions of this study. 
CORRELATION OF HBA1C LEVELS OF PROLANIS PATIENTS WITH DIABETES MELLITUS TO MICROALBUMINURIA LEVELS AT KESUGIHAN I HEALTH CENTER Nugrahaeni, Dian Rahma; Faizal, Imam Agus; Nugroho, Yusuf Eko
Jurnal Mitra Kesehatan Vol. 8 No. 1 (2025): Jurnal Mitra Kesehatan
Publisher : STIKes Mitra Keluarga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47522/jmk.v8i1.422

Abstract

Introduction : Chronic hyperglycemia and disorders of carbohydrate, fat, and protein metabolism are signs of a metabolic disease known as diabetes mellitus. The disease is caused by abnormalities in the secretion of insulin or the work of insulin. Higher HbA1C levels indicate uncontrolled diabetes mellitus, and in high-risk patients, long-term complications that can be fatal. The presence of albumin in the urine of people with diabetes mellitus causes a problem known as diabetic nephropathy. In a damaged glomerular condition, kidney leakage can occur which allows proteins, especially albumin, to seep into the urine. The purpose of this study was to find out whether there was a relationship between HbA1C levels of prolanis diabetic mellitus patients and microalbuminuria levels at the Kesugihan I Health Center. Method: This study used a cross-sectional description design, with a research sample of results from the HbA1C and microalbuminuria examination of prolanis patients at the Kesugihan I Health Center from January to March 2025, meeting the inclusion and exclusion criteria of 60 samples. Result: The Spearman correlation test for this study found a correlation value of -0.163 between HbA1C and microalbuminuria levels, with a p-value of 0.214. Conclusion: The conclusion of this study is that there is no correlation between HbA1C levels of prolanis patients with diabetes mellitus and microalbuminuria levels at the Kesugihan I Health Center.
Analisis Profil Protein dan Total Protein Tempe Mendoan Asal Cilacap Dengan Berbagai Durasi Fermentasi Menggunakan SDS-PAGE Putri, Reza Amelia; Farabi, Meka Faizal; Nugroho, Yusuf Eko
Jurnal Analis Kesehatan Vol. 14 No. 2 (2025): JURNAL ANALIS KESEHATAN
Publisher : Department of Health Analyst, Politeknik Kesehatan, Kementerian Kesehatan Tanjungkarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jak.v14i2.5169

Abstract

Di Indonesia tanaman kedelai (Glycine max (L) Merill) banyak dibudidayakan, tetapi bukan tanaman asli Indonesia. Salah satu produk olahan kedelai yang gemar dikonsumsi oleh masyarakat adalah tempe, merupakan makanan tradisional dari Indonesia. Penelitian ini bertujuan untuk mengetahui total protein dan profil protein tempe mendoan dengan durasi fermentasi 24, 48, dan 72 jam, guna mengetahui waktu fermentasi terbaik dalam menghasilkan kandungan protein yang tinggi. Analisis profil protein dan total protein dilakukan secara deskriptif yang ditabulasi dalam bentuk tabel dan dihitung rata-rata menggunakan JASP serta Microsoft Excel untuk mengetahui nilai absorbansi kurva baku. Hasil penelitian menunjukkan bahwa total protein tertinggi pada fermentasi 48 jam sebesar 2,65 μg/μL, diikuti oleh fermentasi 72 jam (2,32 μg/μL) dan terendah pada fermentasi 24 jam (1,48 μg/μL). Hasil SDS-PAGE menunjukkan bahwa semua sampel memiliki pita protein minor dengan berat molekul 74 kDa, 70 kDa, 48 kDa, 40 kDa, 31 kDa, 26 kDa, dan 10 kDa. Pada fermentasi 48 jam terdapat pita protein mayor 40 kDa, mengindikasikan bahwa pita yang lebih tebal (Mayor) memiliki konsentrasi protein yang lebih tinggi. Hasil penelitian menunjukkan bahwa fermentasi 48 jam merupakan waktu yang optimal.
PEMERIKSAAN KADAR HEMOGLOBIN PADA SISWI YANG TIDAK MENGKONSUMSI TABLET PENAMBAH DARAH DAN MENGKONSUMSI TABLET PENAMBAH DARAH DENGAN BUAH–BUAHAN DI SMK MA’ARIF NU 2 AJIBARANG Tutirofingah; Nugroho, Yusuf Eko; Pangesti, Ira
Pharmaqueous: Jurnal Ilmiah Kefarmasian Vol. 7 No. 1 (2025): Volume 7, Nomor 1, Mei 2025
Publisher : Universitas Al-Irsyad Cilacap

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36760/jp.v7i1.625

Abstract

Anemia merupakan salah satu masalah kesehatan utama pada remaja putri yang disebabkan oleh rendahnya kadar hemoglobin, terutama akibat kekurangan zat besi. Penelitian ini bertujuan untuk mengetahui perbedaan kadar hemoglobin pada siswi yang tidak mengkonsumsi tablet penambah darah dan yang mengkonsumsi tablet penambah darah dengan tambahan konsumsi buah-buahan di SMK Ma’arif NU 2 Ajibarang. Penelitian ini menggunakan pendekatan kuantitatif deskriptif komparatif dengan desain cross-sectional. Sampel terdiri dari 108 siswi yang dibagi menjadi tiga kelompok: tanpa perlakuan, konsumsi tablet penambah darah, dan konsumsi tablet penambah darah dengan buah-buahan. Pemeriksaan kadar hemoglobin dilakukan sebelum dan sesudah perlakuan menggunakan alat Easy Touch GCHB. Analisis data dilakukan menggunakan uji ANOVA dan uji lanjutan Tukey HSD. Hasil penelitian menunjukkan adanya perbedaan signifikan kadar hemoglobin antara kelompok yang tidak mengkonsumsi tablet penambah darah dan yang mengkonsumsi tablet penambah darah (p=0,014). Namun, tidak terdapat perbedaan signifikan antara kelompok konsumsi tablet saja dan tablet dengan buah-buahan (p=0,743). Dapat disimpulkan bahwa konsumsi tablet penambah darah berpengaruh signifikan terhadap peningkatan kadar hemoglobin, sementara penambahan buah-buahan tidak menunjukkan peningkatan yang signifikan secara statistik.
Ekspresi TNF-α Histopatologi Ginjal Pada Tikus Model Sepsis Sebagai Efek Preventif Diberi Nanoemulsi Burdock Yang Diinduksi Bakteri MRSA Faizal, Imam Agus; Nugroho, Yusuf Eko; Fauziah, Rahma Shifa; Yunadi, Frisca Dwi; Swandari, Mika Tri Kumala
Jurnal Sain Veteriner Vol 44, No 1 (2026): April
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.107607

Abstract

One of the natural ingredients utilized as a traditional medicinal herb is Arctium lappa L. or commonly called burdock. This plant has roots, leaves, seeds that have been used to treat infections and various skin disorders. Burdock is used for anti-inflammatory, anti-cancer, infection-fighting, and anti-tumor regulating activities. The purpose of this research is to determine the effect of Arctium lappa L. root extract on renal histopathology and tumor necrosis factor-alpha (TNF-α) expression in white rat sepsis model after Methicillin-Resistant Staphylococcus aureus (MRSA) bacteria administration. Where in this research stage is divided into 5 groups of test animal treatment. Each group was injected with MRSA bacterial suspension with a standard MC Farland turbidity test of 0.5. The results of this research obtained that burdock root extract is able to inhibit inflammation of sepsis test animals caused by MRSA bacteria with the average value of TNF- α reaction presentation, namely K1 (-) (13.632; 14.756), K2 (+) (33.291; 29,568), K3 (150 mg/kg BW) (35,458; 33,273), K4 (300 mg/kg BW) (36,120; 28,731) K5 (450 mg/kg BW) (28,086; 228,084. So it can be stated that Arctium lappa L root extract is able to inhibit inflammation with the use of the most effective dose of 450 mg/kg BW.