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All Journal Edu Masda Journal Pharmaceutical Science Journal Jurnal Kefarmasian Indonesia Indonesia Economic Journal PharmaCine: Journal of Pharmacy, Medical and Health Science Analit: Analytical And Environmental Chemistry
Intan Tsamrotul Fu’adah
Department Of Pharmacy, STIKes Widya Dharma Husada, South Tangerang, Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Comparison of Indonesian Herbal Drinks Empon-empon and Wedang Pokak for Vitamin C Content and Antioxidant Activity Nur Hasanah; Sheila Meitania Utami; Intan Tsamrotul Fu’adah; Dwina Ramadhani Pomalingo; Beny Maulana Satria; Pugoh Santoso; Silvester Maximus Tulandi; Ayu Indayanti Ismail
Jurnal Kefarmasian Indonesia VOLUME 15, NUMBER 2, JULY-DECEMBER 2025
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

Empon-Empon and Wedang Pokak are traditional Indonesian herbal drinks prepared from various spices through a simple production process. Empon-Empon consists of red ginger, turmeric, nutmeg, aromatic ginger, bay leaves, lemongrass, galangal, cinnamon, and cloves. At the same time, Wedang Pokak contains red ginger, cloves, lemongrass, cinnamon, cardamom, pandan leaves, and star anise. Both drinks are widely recognized as sources of antioxidants and vitamin C, and are believed to strengthen the immune system. This study aimed to determine the vitamin C content and antioxidant activity of Empon-Empon and Wedang Pokak. Vitamin C analysis was carried out using UV-Vis spectrophotometry, which showed a maximum wavelength at 245 nm with a linear regression equation y = 0.0434x – 0.0967 (R² = 0.9942). The vitamin C content was 23.33 µg/mL (0.233%) in Empon-Empon and 20.28 µg/mL (0.202%) in Wedang Pokak. Antioxidant activity was determined using the DPPH method, yielding inhibition percentages of 21.28% (20 µg/mL), 40.16% (40 µg/mL), 46.48% (60 µg/mL), and 59.67% (80 µg/mL) for Wedang Pokak, with an IC₅₀ value of 63.33 µg/mL. This activity was lower than Empon-Empon (IC₅₀ 40.53 µg/mL) and pure vitamin C (IC₅₀ 3.77 µg/mL). In conclusion, Empon-Empon exhibited higher vitamin C content and stronger antioxidant activity than Wedang Pokak, highlighting its potential as a functional drink to support health.
Co-Authors Ade Imam Muslim Amelia Nurul Hakim Andriyani Rahmah Fahriati Ayu Indayanti Ismail Beny Maulana Satria Dwina Ramadhani Pomalingo Dwina Ramadhani Pomalingo Esadini, Aya Rana Firdha Senja Maelaningsih Gina Aulia Gina Aulia Hartono, Irwan Heri Satria Heri Satria Humaira Fadhilah Kurniawati, Dewi Indah Lia Zia Ulhaq Linawati Linawati Magdalena Niken Oktovina Nafisah, Lina Nasar, Nur Afni Syariah Nur Afni Syariah Nasar Nur Hasanah Nurhasanah Nurhasanah Nurhasanah Nurhasanah Pomalingo, Dwina Ramadhani Pugoh Santoso Rubiana, Amalia Cinta S.Pd. M Kes I Ketut Sudiana . Saputri, Dea Maulidi Sayyidah Sayyidah Sheila Meitania Utami Silvester Maximus Tulandi Siva Fauziah, Siva Suripto Dwi Yuwono Suripto Dwi Yuwono, Suripto Dwi Tania Rizki Amalia Usi Yusnitaswari Utami, Anissa Vina Fauziah Zulfahrin, LM