Article Per Year (5 Year)
p-Index From 2020 - 2025
1.829
P-Index
This Author published in this journals
All Journal Jurnal Studi Agama dan Masyarakat Majalah Kedokteran Sriwijaya Jurnal Penelitian Agrosamudra JIKEM: Jurnal Ilmu Komputer, Ekonomi dan Manajemen Jurnal RSMH Palembang Nida Al-Qur'an: Jurnal Pengkajian Islam Jejak digital: Jurnal Ilmiah Multidisiplin
Ahmad Rasyid
Unknown Affiliation
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Languange, Linguistic, Communication & Media Library & Information Science Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 10 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Majalah Kedokteran Sriwijaya

 1 
CORRELATION BETWEEN ETHAMBUTOL THERAPY DURATION AND ZINC SERUM LEVEL WITH COLOUR VISION DEFICIENCY IN TUBERCULOSIS PATIENTS Devi Azri Wahyuni; Mira Retna Tetiana; Mgs Irsan Saleh; Ahmad Rasyid
Majalah Kedokteran Sriwijaya Vol 52, No 2 (2020): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v52i2.11975

Abstract

Tuberculosis is one of the most common disease in Indonesia. Ethambutol is one of the main regiment therapy for patient with tuberculosis. Duration of ethambutol therapy depends on what category of tuberculosis patient. Ethambutol intake can cause optic neuropathy with colour vision deficiency as an early symptom. Ethambutol therapy can also cause decrease of zinc serum level and it is cause by zinc chelate that can be found in ethambutol. The purpose of this study was to determine the correlation between duration of ethambutol therapy and zinc serum level with colour vision deficiency which examined with Farnsworth Munsell 100 Hue in tuberculosis patients. This is an observational explorative study. Colour vision is xamined with Farnsworth Munsell 100 Hue and zin serum level is detected by blood sample. Data was analyzed by correlation study. Correlation statistic between ethambutol therapy duration with colur vision using Spearman coreelation study found that r = 0,5 and p = 0,00, whereas in correlation between zinc serum level with colour vision found that r = 1,68 and p = 0,32. There is significant correlation and positive direction between ethambutol therapy duration with colour vision deficiency. Even though there is no significant correlation between zinc serum level with colour vision deficiency, there is a strong correlation.
COMPARISON OF COPPER LEVEL AND COLOR VISION IN PULMONARY TUBERCULOSIS PATIENTS BEFORE AND AFTER ETHAMBUTOL TREATMENT IN CATEGORY I AND II Devi Azri Wahyuni; Febria Restissa; Ahmad Rasyid; Erial Bahar
Majalah Kedokteran Sriwijaya Vol 52, No 2 (2020): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v52i2.11969

Abstract

Copper as a metal chelator in ethambutol may interfere oxidative phosphorylation and mitochondrial function that are useful in the formation of ATP, so that long-term damage can cause apoptosis and interfere color vision. This study aims to determine the correlation between duration of ethambutol and copper levels in serum with color vision disorder examined with Farnsworth Munsell 100 Hue (FM100) in patients with tuberculosis. This study was an explorative observation of 20 samples during November 2017 - January 2018 period. Comparative analysis using independent t-test, paired t-test, Wilcoxon test and Mann-Whitney test, while correlation analysis using Spearman's test and Pearson's test. There was a significant difference of FM100value before and after in category I (p=0.000) with increase of total error value 11.80+5.31 or category II (p=0.000) with increase of total error value 15.00+7.41. There was significant difference of Cu2+  level before and after in category I (p=0.005) with decrease of  Cu2+ level 15.57+5.04 mg/dL or category II (p=0.005) with decrease of  Cu2+ level 31.66+7.35 mg/dL. The duration of Ethambutol was related to changes in color vision examined with FM100.
Co-Authors Ade Novita Ahmad, Zen Alfajri, Alfajri Alif Fathurrachman As-Syifa Salsabila Az-zahra, Dwi Wahyuni Bayu Andrian Dea Musvita Devi Azri Wahyuni Dewo Prasetiyo Dwi Indira Elzan Zulqad Maulana Erial Bahar Febria Restissa Ganda Elsandro Tumanggor Husnul Hotima Iswahyudi Linda Andriani Mgs Irsan Saleh Mila Erliana Mira Retna Tetiana MUHAMMAD ILHAM Muhammad Novran Chalik Muhammad Ridho Muhlisin Muliyani Mustafa, Nurul Nadiah Binti NURHALIMAH Nurul Intan, Nurul Rahmadiyanti Rouly Pasaribu Sobri Sobri Sudarto