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All Journal Jurnal Respirologi Indonesia Respiratory Science
Elhidsi, Mia
Department Of Pulmonology And Respiratory Medicine, Faculty Of Medicine, Universitas Indonesia, Persahabatan General Hospital, Jakarta
Health Professions Medicine & Pharmacology

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Proportions of Hypertension in Stable COPD Patients at the National Respiratory Center Persahabatan Hospital Dewantoro, Luhur; Wiyono, Wiwien Heru; Yunus, Faisal; Agustin, Heidy; Damayanti, Triya; Antariksa, Budhi; Fachrucha, Fanny; Samoedro, Erlang; Elhidsi, Mia
Jurnal Respirologi Indonesia Vol 44 No 3 (2024)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v44i3.774

Abstract

Background: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. Most of these deaths are related to cardiovascular disease. This is due to systemic inflammation that causes increased vascular stiffness and hypertension. These comorbidities lead to poor quality of life, low exercise tolerance, and an increased risk of hospitalization. This study aims to report the proportion of hypertension among stable COPD patients in the Indonesian population.Methods: This cross-sectional study was conducted at the National Respiratory Center Persahabatan Hospital between February and March 2023. Stable COPD patients admitted to the Asthma and COPD Polyclinic who met the criteria were enrolled. Clinical information, vital signs, spirometry results, and DLCO measurements were collected.Results: There were 84 subjects participating in this study. The result of this study shows a 60.7% proportion of hypertension in stable COPD patients. Hypertension has a significant correlation with pulmonary functional values (P=0.021), severity degree of clinical COPD (P=0.004), Brinkman index (P=0.008), and age (P=0.0001). However, hypertension association with COPD duration (P=0.505) and DLCO (P=0.122) were not significant.Conclusion: The hypertension proportion in stable COPD Indonesian patients is 60.7%. Hypertension shows a significant association with pulmonary function values, severity degree of clinical COPD, Brinkman index, and age. 
Comparison Between Imprint Cytology and Histopathology Results in Pleural Effusion Cases Undergoing Pleuroscopy Wahju Aniwidyaningsih; Dian Prastiti Utami; Dicky Soehardiman; Mohammad Fahmi; Prasenohadi; Mia Elhidsi; Ginanjar Arum; Tina Reisa; Menaldi Rasmin; Ruth Emalian Sembiring; Romi Beginta; Eylin Rahardjo; Flora Dameria; Ni Putu Laksmi Ananda Martini
Jurnal Respirologi Indonesia Vol 46 No 2 (2026)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v46i2.1111

Abstract

Background: Pleuroscopy is a valuable minimally invasive procedure for evaluating undiagnosed pleural effusion. Rapid diagnosis of malignancy is often needed to reduce procedure time and patient discomfort, particularly when pleurodesis is planned. Imprint cytology is a quick and simple method, though underutilized in pleuroscopy practice in Indonesia. This study aimed to compare the diagnostic yield of imprint cytology and histopathology in pleural effusion cases undergoing pleuroscopy. Methods: This retrospective observational study was conducted from August to November 2024 and included patients with pleural effusion who underwent diagnostic pleuroscopy. Pleural biopsies were taken using forceps. Imprint cytology was performed by directly smearing the biopsy tissue onto slides, followed by staining. Histopathology was done using standard tissue processing. Results: Of the 25 patients who underwent pleuroscopy, 14 met the inclusion criteria. Pleuroscopic findings varied, with the most common being mass lesions (35.7%), followed by multiple nodules (21.4%) and sago-nodules (14.3%). Histopathology revealed malignancy in 10 patients (71.4%) and non-malignant in 4 (28.6%). Imprint cytology detected malignancy in 12 patients (85.7%) and non-malignant findings in 2 patients (14.3%). Conclusion: Imprint cytology offers a rapid and reliable diagnostic method during pleuroscopy, particularly in resource-limited settings. It may facilitate early detection of malignancy and support timely clinical decision-making.
Malignant Pleural Effusion: A Contemporary Approach to Diagnosis and Personalized Management Theresia Rasta Karina; Hana Khairina Putri Faisal; Mia Elhidsi
Respiratory Science Vol. 6 No. 2 (2026): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i2.214

Abstract

Malignant pleural effusion (MPE) is a manifestation of advanced malignancy characterized by abnormal accumulation of pleural fluid due to tumor cell infiltration. It most commonly originates from lung, breast cancer, or lymphoma and is associated with dyspnea, chest pain, and impaired quality of life. Diagnosis of MPE is established through pleural fluid cytology or histopathological confirmation, supported by radiological imaging. Liquid biopsy offers a minimally invasive approach for detecting molecular alterations. Although diagnostic and therapeutic modalities have improved, management remains primarily palliative. Therapeutic thoracentesis, chemical pleurodesis using talc, and indwelling pleural catheter (IPC) placement are the main palliative strategies. Combination therapy of IPC with talc slurry demonstrates higher rates of spontaneous pleurodesis and shorter hospital stays. Systemic therapies such as chemotherapy, targeted therapy, and immunotherapy provide additional disease control in selected patients. Although current approaches have improved diagnostic and therapeutic outcomes, most treatments remain palliative. Therefore, a multidisciplinary and personalized strategy is essential to optimize patient quality of life. This review underscores the importance of early diagnosis and management of malignant pleural effusion, including cytology, pleural biopsy, imaging, and liquid biopsy, as well as therapeutic approaches such as thoracentesis, pleurodesis, indwelling pleural catheter, systemic therapy, and palliative care.
Risk and Prevention of Infections in the Bronchoscopy Room Wahju Aniwidyaningsih; Indah Puspita Sari; Anis Karuniawati; Fathiyah Isbaniah; Mia Elhidsi; Ni Putu Laksmi Ananda Martini
Respiratory Science Vol. 6 No. 3 (2026): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i3.217

Abstract

Bronchoscopy is a widely used diagnostic and therapeutic procedure in pulmonary medicine, with increasing utilization as technology advances. However, it is also associated with a risk of infection, which may negatively impact patient outcomes, particularly in individuals with underlying lung disease or immunocompromised conditions. The Centers for Disease Control and Prevention (CDC) has reported that endoscopic procedures, including bronchoscopy, are among the most frequently implicated medical devices in healthcare-associated outbreaks. Post-bronchoscopy infections, although relatively uncommon (0.2–5.2%), may lead to serious complications such as pneumonia, lung abscess, and empyema. These infections can originate from endogenous respiratory flora or from exogenous contamination related to inadequate bronchoscope reprocessing. This narrative review aims to summarize current evidence on infection risks, sources of transmission, and preventive strategies in the bronchoscopy setting, including occupational risks to healthcare workers. Strengthening infection control practices is essential to improve patient safety and reduce the risk of transmission in bronchoscopy units.
Aeromedical Concern for Patients with Acute Respiratory Distress Syndrome (ARDS) during Air Medical Evacuation Monica Djaja Saputera; Mia Elhidsi; Retno Wibawanti
Respiratory Science Vol. 7 No. 1 (2026): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v7i1.204

Abstract

Acute respiratory distress syndrome (ARDS) is a clinical syndrome of acute respiratory failure characterized by arterial hypoxemia and bilateral pulmonary opacities. In recent years, the incidence of ARDS has rapidly increased due to Coronavirus Disease 2019 (COVID-19). This has resulted in an increased need for patient referral to more adequate health care facilities using air ambulance through air medical evacuations. The purpose of this study is to synthesize the aeromedical concerns in ARDS patients undergoing air medical evacuation, focusing on physiological challenges and mechanical ventilation issues in flight. Acute hypobaric hypoxia that occurs during air medical evacuation inside the cabin (altitude 6,000–8,000 ft) will trigger a hyperventilation response that can lead to respiratory alkalosis. This condition will not only worsen the hypoxemia state but also deteriorate the patient’s clinical symptoms. Additionally, changes in altitude and atmospheric pressure inside the aircraft cabin also pose risks to patients using invasive mechanical ventilation. Not only can it disrupt the settings of medical equipment, but it can also cause pulmonary barotrauma, which can lead to pneumothorax. To prevent these various impacts, air medical evacuation must be carried out by a multidisciplinary team with considerations for the use of medications and manoeuvres for invasive mechanical ventilation. The key parameters to assess fitness-to-fly among ARDS patients include the vital signs, heart rhythm, tidal volume, end-tidal carbon dioxide, neuromuscular blockade, inspiratory pressure peak, along with some parameters related to the use of invasive mechanical ventilation, such as oxygen pressure, FiO2, atmospheric pressure, power status, turbine function, and malfunction indicator.
Co-Authors Adityo Wibowo Agus Dwi Susanto Agustin, Heidy Alatas, Mohammad Fahmi Alatas, Muhamad Fahmi Anis Karuniawati Aniwdyaningsih, Wahju Aniwidyaningsih, Wahju Aritonang, Rachel S Bies, Asri Liqditta Budhi Antariksa Budi Prasetio Nugroho Damayanti, Triya Desianti, Ginanjar Arum Desiyanti, Ginanjar Arum Dewantoro, Luhur Dian Prastiti Utami Dianiati Kusumo Sutoyo Dicky Soehardiman Elisna Syahruddin Erni Mudhiati Eylin Rahardjo Faisal Yunus Faisal, Hana Khairina Putri Fanny Fachrucha Flora Dameria Ginanjar Arum Indah Puspita Sari Isbaniah, Fathiyah Martini, Ni Putu Laksmi Ananda Menaldi Rasmin Menaldi Rasmin Mohammad Fahmi Monica Djaja Saputera Navratilova, Melfia Ni Putu Laksmi Ananda Martini Ni Putu Laksmi Ananda Martini Prasenohadi Rahma Ayu Indahati Reisa, Tina Retno Wibawanti Romi Beginta Ruth Emalian Sembiring Samoedro, Erlang Soehardiman, Dicky Taufik, Feni Fitriani Theresia Rasta Karina Tina Reisa Wahyu Soebekti Wiwien Heru Wiyono Zaini, Jamal