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All Journal Acta Pharmaceutica Indonesia Jurnal Farmasi Sains dan Komunitas Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Syntax Literate: Jurnal Ilmiah Indonesia JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) JSFK (Jurnal Sains Farmasi & Klinis) NUSANTARA : Jurnal Ilmu Pengetahuan Sosial JFL : Jurnal Farmasi Lampung Journals of Ners Community Jurnal Ilmu Kefarmasian Indonesia Jurnal Pendidikan dan Konseling Jurnal Kesehatan Poltekkes Kemenkes RI Pangkalpinang Jurnal Ners Jurnal Ekonomi Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Sciences of Pharmacy Jurnal Keperawatan Profesional (KEPO) Jurnal Sains dan Kesehatan
Ramadaniati, Hesty Utami
Universitas Pancasila, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Syntax Literate: Jurnal Ilmiah Indonesia

 1 
Evaluasi Penggunaan Antibiotika Pada Pengobatan Sepsis Neonatal Dengan Metoda Gyssens di RSAD Salak Bogor Tahun 2018 Patminingsih, Nanik; Ratih Laksmitawati, Dian; Utami Ramadaniati, Hesty
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : CV. Ridwan Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (723.942 KB) | DOI: 10.36418/syntax-literate.v5i7.1468

Abstract

Sepsis merupakan disfungsi organ yang mengancam kehidupan yang diakibatkan oleh disregulasi imun terhadap infeksi. Pemberian antibiotika yang sesuai merupakan salah satu kriteria dalam tata laksana sepsis. Penelitian ini bertujuan untuk mengevaluasi penggunaan antibiotika pada pasien sepsis neonatal. Penelitian dilakukan secara obsevasi analitik dengan alur prospektif. Sebanyak 34 sampel pasien sepsis neonatal dilakukan pemantauan terapi obat. Karakteristik dominan bayi yang mengalami sepsis adalah bayi laki-laki dengan prosentase 59%, terdapat 62% Berat Badan Bayi Cukup (BBLC), 59% jenis sepsis Early Onset Sepsis (EOS), kehamilan cukup bulan 79% dan riwayat persalinan normal 62%. Penggunaan antibiotika terbanyak adalah kombinasi seftriakson-gentamisin sebanyak 50%, kombinasi ampisilin-gentamisin sebagai lini pertama sebanyak 35%, ceftriakson tunggal 9% serta ceftazidim tunggal dan kombinasi seftazidim-gentamisin masing-masing 3%. Hasil evaluasi Gyssens menunjukkan hasil kerasionalan antibiotika 18%, ketidakrasionalan 82%. Hasil statistic menunjukkan bahwa nilai sig yang didapat sebesar 0.912 > alpha 0.05. Hal ini menunjukkan H0 diterima atau tidak adanya hubungan rasionalitas dengan lama hari sembuh. Penggunaan rasional atau tidaknya tidak ada hubungannya dengan seorang pasien lebih cepat atau lebih lama dalam penyembuhan. Kata kunci : Penggunaan antibiotika; sepsis neonatal; metoda Gyssens
Analisis Drug Related Problems dan Pengaruhnya terhadap Pengendalian Glukosa Darah pada Pasien Covid-19 dengan Komorbiditas Diabetes Melitus Tipe 2 Yoppy Mayrosa; Hesty Utami Ramadaniati; Dian Ratih Laksmitawati; Ivans Panduwiguna
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v8i11.13955

Abstract

This study aims to anayze the effect of drug related problems (DRPs) on glycemic control in COVID-19 patients with comorbid diabetes mellitus type 2. This research is a cross-sectiona study using retrospective data obtained from secondary data from the medica records of Covid-19 patients. with type 2 diabetes mellitus. The research location was at Jati Padang Hospita. The sample consisted of 76 medica records with total sampling method. Data collected using PCNE V9.00 were then tested using the Wilcoxon test comparing initia GDS in hospita with GDS at the end of patient discharge, the Chisquare test which correlated changes in GDS with patient clinica outcomes and the Spearman test which linked changes in GDS with DRPs, characteristics of Covid-19 patients with diabetes mellitus predominant age 46-55 years (30.3%), predominant sex mae (51.3%), length of stay 6-10 days (64.5%), profile of drug use that is often used antivira, antibiotics, vitamins and supplements, symptomatic and antidiabetic (100%). The most common comorbidities were hypertension (60.4%), the incidence of DRPs (92.1%), the most common fina GDS was hyperglycemia (≥ 200 mg/dL) (65.8%). 58 patients were discharged with a negative sample (76.3%). The results of the Wilcoxon test on blood glucose showed differences in blood glucose at the beginning and at the end. The results of the Chi-square test between changes in blood glucose and the patient's clinica outcome (p>0.05) showed that there was no significant relationship between changes in blood glucose levels and the patient's clinica outcome. Spearmen's correlation test results (p>0.05) showed a significant relationship between DRPs and changes in patient's blood glucose. The correlation between the incidence of DRPS and blood glucose (0.169) shows a weak relationship. It can be interpreted that DRPs do not realy affect changes in blood glucose in patients at Jati Padang Hospital.
Co-Authors Ahmad Subhan Amaliyah Amaliyah Andam Dewi Pertiwi Andayani, Nurita Azizah, Zata Yumni Bayu Pertiwi Christine Meidiawati Dian Ratih Laksmitawati Dwi Aryanti, Anindita Dwi Oktiano Dwirani Amelia Erna Kristin Ivans Panduwiguna Kurniati, Rizki Lina Karlina Muzakar, Cholid Neni Rahmani Ni Made Dwi Sandhiutami Nurita Andayani Nurlela Nurlela Nurul Azizah Oktiano, Dwi Oriza Safrini Oriza Safrini Patminingsih, Nanik Prih Sarnianto Prih Sarnianto Prih Sarnianto Prih Sarnianto Prih Sarnianto Rahmani, Neni S. Mardiko, Etty S.Farm., M.Farm., Apt, Sondang Khairani Saragi, Sahat Sarnianto, Prih Sesilia Andriani Keban Shirly Kumala Sriyono, Bimantoko Hadi Suny Koswara Rahajeng Sutarno Syahputri, Devina Harti Taufik Hidayat Vera Mulyawantie Yati Sumiyati, Yati Yazid, Ricky Chaerul Yoppy Mayrosa Yusi Anggriani Yusi Anggriani Zata Yumni Azizah