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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal SOLMA Sainstech Farma: Jurnal Ilmu Kefarmasian Jurnal Ilmiah Medicamento SAINSTECH: Jurnal Penelitian dan Pengkajian Sains dan Teknologi Mestaka: Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian Masyarakat Bangsa Jurnal Kefarmasian Indonesia
Kusuma, Ika Maruya
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Journal : Jurnal Ilmiah Medicamento

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Skincare Antijerawat: Formulasi Masker Gel Peel-Off Etil P-Metoksisinamat dari Kaempferia galanga L dengan Polivinill Alkohol sebagai Gelling Agent Kusuma, Ika Maruya; Indrawati, Teti; Zulfah, Zulfah
Jurnal Ilmiah Medicamento Vol 11 No 2 (2025): Jurnal Ilmiah Medicamento (In progress)
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v11i2.11465

Abstract

Herbal medicines are increasingly used as antibacterial therapy due to their accessibility and affordability. Kaempferia galanga L. (kencur) rhizome contains ethyl p-methoxycinnamate (EPMS), an active compound with anti-acne properties. EPMS at 1.2% in cream formulations has shown antibacterial activity against Propionibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus. However, creams are unsuitable for oily skin as they may worsen acne. Peel-off gels offer a better alternative because it is non-greasy, supports exfoliation, stimulates cell regeneration, minimizes pores, and helps cleanse and moisturize the skin. This study aimed to formulate a physically stable anti-acne peel-off gel containing EPMS using polyvinyl alcohol (PVA) at 10% and 12%. EPMS was isolated from kencur rhizome and incorporated into gel bases. Evaluations included organoleptic properties, viscosity, homogeneity, pH, drying time, spreadability, and accelerated stability at 27 ± 2 °C and 40 ± 2 °C for 21 days. Results showed that EPMS can be successfully formulated into peel-off gels with PVA 10% and 12%. The gels exhibited yellowish-white color, honey-like odor, homogeneity, pH 5.21–5.35, drying time 17–30 minutes, spreadability 55–68 mm, and viscosity 4,900–16,000 cPs. All formulations maintained physical stability under test conditions. This study provides a scientific basis for the development of natural-based cosmetic products that are safe, particularly for oily skin, and do not worsen acne conditions.
Co-Authors ., Herdini Ainun Wulandari Akhatik, Nurul Alodia, Anita Andini, Issri Mila Nova Azizah, Shandy Chairunnisa, Brilliany Desi, Ika Pusma Djuhariah, Yayah Siti Erwi Putri Setyaningsih Febriani, Amelia Firdamayanti, Firdamayanti H Herdini Jastian, Silfia Yohana Jaya, Rendy Indra Krisnawati, Indah Manalu, Rosario Trijuliamos Mellova Amir Munawarohthus Sholikha Muzallifah, Muzallifah Nopianti, Hermila Nugrahani, Hervianti Nurfitria Pontoan, Jenny Putri, Elvina Triana Rachmatiah, Tiah Setiadi, Fandy Rezha Siswati Siswati Subaryanti, Subaryanti Syafriana, Vilya Teodhora, Teodhora Teti Indrawati Veryanti, Putu Rika Widyapratiwi, Ritha Zahra, Nada Zulfah Zulfah