Article Per Year (5 Year)
p-Index From 2021 - 2026
1.756
P-Index
This Author published in this journals
All Journal International Journal of Public Health Science (IJPHS) International Journal of Integrated Health Sciences Majalah Kedokteran Bandung Universa Medicina JSMARTech : Journal of Smart Bioprospecting and Technology Narra J The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Maghfirah, Desi
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health

Published : 11 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 11 Documents
Search

 1   2 
Gastrointestinal Manifestations and Neutrophil-to-Lymphocyte Ratio as Marker of Occult Bleeding in COVID -19 Maghfirah, Desi; Yusuf, Fauzi; Marisa, Marisa; Eljatin, Muhammad Ridho Akbar
International Journal of Integrated Health Sciences Vol 13, No 2 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v13n2.4210

Abstract

Background: Coronavirus disease 2019 (COVID-19) was initially recognized as a respiratory illness; however, it has been gradually recognized as a disease that affects multiple organ systems, including the gastrointestinal (GI) tract. GI involvement ranges from mild symptoms, such as nausea and diarrhea, to complications like gastrointestinal bleeding. The neutrophil-to-lymphocyte ratio (NLR) has been proposed as a simple biomarker of inflammation and disease severity in COVID-19.Objective: To describe gastrointestinal manifestations of COVID-19 and examine the association between NLR levels and occult gastrointestinal bleeding.Methods: This cross-sectional study was conducted in 2021 at the New-Emerging and Re-Emerging Infectious Diseases inpatient unit of Dr. Zainoel Abidin General Hospital, Banda Aceh, Indonesia. COVID-19-positive patients aged ≥18 years with gastrointestinal symptoms were included, excluding those who were pregnant or had pre-existing GI disorders. Data were collected from medical records and patient interviews. Statistical analysis was performed using the Mann–Whitney U test, with p < 0.05 considered significantResults: The most frequent symptoms were appetite loss and nausea (93%), bloating and vomiting (87%), and diarrhea (57%). Occult GI bleeding occurred in seven patients (23.3%) who had significantly higher NLR values than those without bleeding (p = 0.041).Conclusion: The most frequent GI manifestations of COVID-19 are loss of appetite, nausea, bloating, vomiting, and diarrhea, while occult gastrointestinal bleeding occurs in about one-fourth of cases. Elevated NLR levels are associated with occult bleeding, suggesting its potential role as a simple and accessible biomarker of intestinal inflammation and disease severity.
Co-Authors Alfi Syahrin, Alfi Azzaki Abubakar, Azzaki Chatarina Umbul Wahyuni Darnifayanti, Darnifayanti Dewi Karlina Rusly Edward, Meutia Nailan Eljatin, Muhammad Ridho Akbar Ezigbo, Eyiuche D. Fauzi Yusuf, Fauzi Febriyanti, Sherina Arfi FIRDAUSA, SARAH Gunawan , Andrie Gunawan, Andrie Heltomi, Mirza Hendra Zufry, Hendra Ho, Khek Yu Isitua, Chinwe C. Ismida, Fitri Dewi Kurniawan Kurniawan Marisa Marisa Muhammad Yusuf Muhsin Muhsin Mulia, Vera Dewi Purnomo, Avisena Gatot Riswan, Muhammad Salam, Nurbahri L Sari, Fitrah Subhan Rio Pamungkas, Subhan Rio