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All Journal Pharmaceutical Journal of Indonesia Jurnal Dunia Farmasi Jurnal Pelayanan dan Pengabdian Masyarakat (Pamas) Jurnal Penelitian Farmasi dan Herbal Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Journal Pharmasci (Journal of Pharmacy and Science) Farmasis: Jurnal Sains Farmasi Jurnal Tata Rias
Fernanda, M.A. Hanny Ferry
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Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Other

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Analisis Semikuantitatif Parasetamol Dalam Jamu Pegal Linu Menggunakan Pemrosesan Gambar Digital dari Hasil Kromatografi Lapis Tipis Fernanda, M.A. Hanny Ferry; Wardani, Ratih Kusuma
Pharmaceutical Journal of Indonesia Vol. 8 No. 1 (2022)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2022.008.01.7

Abstract

Jamu is a pharmaceutical preparation derived from plant simplicia and must meet quality requirements, one of which is that it must not contain medicinal chemicals (BKO). One of the herbs widely circulated and can be obtained freely in the community is herbal medicine for aches and pains. In herbal aches and pains, paracetamol is the BKO suspected to be used in this preparation. This study aimed to develop an analytical method to determine the content of paracetamol BKO in herbal pain relief semi-quantitatively using digital images obtained from Thin Layer Chromatography. The semi-quantitative analysis method is carried out by processing digital images using the qTLC application. The results of this study proved the presence of paracetamol BKO in herbal aches and pains qualitatively using the TLC method. Of the five samples analyzed, only one contained paracetamol BKO with an Rf value of 0.15, while the standard Rf was 0.14. The analysis was then continued with the determination of paracetamol levels semi-quantitatively using digital image processing from the Thin Layer Chromatography results. Based on the results of semi-quantitative analysis, it can be seen that the sample suspected to contain paracetamol contains paracetamol with a concentration of 1,491.31 ppm. The results of this study can provide accurate detection of paracetamol BKO compound determination and semi-quantification limits and have the potential for more quantitative analysis in herbal medicine.
Co-Authors Adhitya Putri Sukmawati Amanda Enggar Valentina Biyan Yesi Wilujeng Chrisnandari , Rosita Dwi Dewi Lutfiati Dibah, Meilindah Farah Dini Murtafi’ah Azmi Kristalinawati, Mepifany Kusumo, Galuh Gondo MASPIYAH Mutimmatul Faidah Nia Kussianti Nirwati, Klara Susi Octaverina Kecvara Pritasari Pritasari, Octaverina Kecvara Rahayu, Ni Luh Ika Shafiyyah, Salma Sherlita Restu Khairina Sudarwati, Tri Puji Lestari Suryandari, Mercyska Usodoningtyas, Sri Wardani, Ratih Kusuma Wilujeng, Biyan Yesi