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All Journal SRIWIJAYA JOURNAL OF MEDICINE PREPOTIF : Jurnal Kesehatan Masyarakat Bioscientia Medicina : Journal of Biomedicine and Translational Research Journal of General Procedural Dermatology and Venereology Indonesia Ebers Papyrus Bali Dermatology Venereology and Aesthetic Journal
Purwoko, Izazi Hari
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Mucocutaneous manifestations of HIV/AIDS infection: literature review Mutia Devi; Muhammad Izazi Hari Purwoko; Suroso Adi Nugroho; Yulia Farida Yahya; Indah Astri Aryani; Kiki Septiafni
Bali Dermatology Venereology and Aesthetic Journal BDVJ - Vol. 5 No. 2 (December 2022)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/dv4m1f17

Abstract

Mucocutaneous manifestations are the first recognized human immunodeficiency virus (HIV) infections. More than 90% of HIV-infected patients develop at least one or more types of typical or atypical skin lesions during the disease. Mucocutaneous manifestation can also indicate the progression of HIV infection and cluster of differentiation 4 (CD4) cell count as an indicator of the development of acquired immunodeficiency syndrome (AIDS). It is important to know mucocutaneous manifestations and their correlation with the patient’s immune status to provide appropriate treatment to improve the patient’s quality of life.
Effectiveness of 5% Channa Striata Extract Gel in Wound Healing: A Double-blind Randomized Controlled Trial Yahya, Yulia Farida; Kurniawati, Yuli; Bahar, Erial; Toruan, Theresia Lumban; Kartowigno, Soenarto; Purwoko, Muhammad Izazi Hari; Octyvani, Tiar Marina
Journal of General - Procedural Dermatology and Venereology Indonesia Vol. 9, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: Snakehead fish (Channa striata, CS) has traditionally been used in Indonesia as a nutrient to promote wound healing. It contains protein highly similar to human protein, which may be involved in wound healing via biological pathways. We aim to determine the effectiveness of the topical 5% CS extract gel in promoting wound healing. Methods: A double-blind, placebo-controlled randomized clinical trial was conducted from June to August 2022 at the Department of Dermatology, Venereology, and Aesthetics of Dr. Mohammad Hoesin Hospital. We allocated 32 post-skin surgery participants with grade I acute superficial wounds on the face, neck, trunk, and extremities into 2 groups with one receiving 5% CS (n=16) and the other receiving placebo (n=16). Both groups applied the treatments twice daily. Assessments of wound healing using modified REEDA (redness, edema, ecchymosis, drainage, approximation) score, wound size, and adverse effects were done at follow-up days 1, 3, and 7. Results: Both groups showed REEDA score improvements on days 1, 3, and 7, with significant difference between both groups identified on day 3 (p=0.038). Wound size improved at each follow-up in all participants, with the 5% CS group being slightly better than the placebo group on day 3 (p>0.05). A mild adverse event was found in only one participant in the 5% CS group (3.1%). Conclusion: Both 5% CS extract gel and placebo had good safety profile and were effective in promoting wound healing. 5% CS extract gel was better at reducing REEDA score.
Co-Authors Adi Agung Anantawijaya D Chandra, Riza Damai Trilisnawati Diba, Sarah Erial Bahar, Erial Fitriani Fitriani . Fitriani Fitriani Fitriani Fitriani Hari Darmawan Hari Darmawan Indah Astri Aryani Karim, Putri Laksmi Kartowigno, Soenarto Kiki Septiafni Muhammad Irsan Saleh Mutia Devi Mutia Devi Mutia Devi Mutia Devi Mutia Devi, Mutia Nofilia Citra Candra Nugroho, Suroso Adi Octyvani, Tiar Marina Raden Pamudji Santoso, Ritchie Soenarto Kartowigno Susanti Budiamal Toruan, Theresia Toruan, Theresia Lumban Widyastuti Yuli Kurniawati, Yuli Yulia Farida Yahya