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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Majalah Kedokteran Sriwijaya Biomedical Journal of Indonesia Paediatrica Indonesiana Majalah Patologi Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Sriwijaya Journal of Surgery Bioscientia Medicina : Journal of Biomedicine and Translational Research

Erial Bahar

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Author-ID : 1878828

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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CORRELATION OF Hba1c LEVELS WITH PUPILLARY RESPONSE TO APRACLONIDINE 0,5% EYE DROPS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS Devi Azri Wahyuni; Nafila Mahida Sukmono; Erial Bahar
Majalah Kedokteran Sriwijaya Vol 52, No 3 (2020): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v52i3.12503

Pupillary reflex abnormalities can result from disorders of the innervation or iris structure of the eye. In people with diabetes mellitus, the pupil size becomes smaller than normal due to neuropathy in innocent sympathetic innervation of the pupil. This neuropathy is associated as a manifestation of uncontrolled diabetes complications. Pupillary response is associated as a general indication of autonomic neuropathy disorders in diabetes mellitus patients. Apraclonidine as an ophthalmic sympathomimetic agent can cause mydriasis, which is likely to identify pupillary sympathetic denervation in type 2 diabetes mellitus patients. This study aimed to find out the correlation between HbA1c levels and pupillary response to 0.5% Apraclonidine eye drops in diabetes mellitus type 2 patients at Mohammad Hoesin Hospital Palembang. Observational research with a correlation test design to investigate the correlation of HbA1c levels with pupillary response to apraclonidine 0.5% eye drops in patients with type 2 diabetes mellitus has been conducted from March to May 2019. The study sample met the inclusion and exclusion criteria of 31 diabetics mellitus type 2 with HbA1c level> 6.5% in the Eye clinic at the Mohammad Hoesin Palembang hospital. In this study 31 patients with type 2 diabetes mellitus with HbA1c levels >6.5 mg% were obtained. The average HbA1c level was 9.5 ± 1.4 mg%, which ranged from 7.6 - 12.6 mg%. The glycemic status of the patients in this study were all (100.0%) in an uncontrolled condition (HbA1c> 7.5 mg%). The estimated duration of diabetes mellitus is 2.7 ± 1.8 years, with a minimum value of 1 year and the largest being 8 years. The average change in pupillary diameter before - after dropping 0.5% apraclonidine was 1.16 ± 1.06 mm, ranging from 0 - 4 mm. There were 9 (29.0%) eyes that did not show any changes. Significant enlargement of pupillary size after dropping 0.5% apraclonidine (p = 0,000). This change in pupil size correlated with the estimated duration of diabetes mellitus (r = 0.436, p = 0.014) and HbA1c levels (r = 0.492, p = 0.005). Pupil size after using 0.5% apraclonidine has a distribution value of 4 (3-6) mm can be interpreted that there are subjects who have no change, but there are patients who have pupils dilated to 6 mm.

COMPARISON OF POST OPERATIVE EPIDURAL ANALGESIA EFFECT USING CONTINUOUS 0.125% BUPIVACAINE WITH BOLUS 3 MG MORPHINE ON INSULIN LEVELS IN PATIENT UNDERGOING LOWER LIMB SURGERY Yovalina R; Zulkifli Zulkifli; Zainal R; Erial Bahar
Majalah Kedokteran Sriwijaya Vol 52, No 3 (2020): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v52i3.12511

The procedure for lower limb surgery is one of the major and long-standing operations. Surgical trauma stimulates the stress response of surgery. The surgical stress response will interfere with stress hormones including insulin. Insulin is an anabolic hormone that is important in the body and has a role in the process of wound healing. Previous studies have shown insulin levels to correlate with increased surgical stress and the type of anesthesia given. This study analyzed differences insulin levels in bupivacaine 0,125% with morphine 3 mg and to compare the analgesia effect of continuous bupivacaine 0,125% with 3 mg morphine epidural in postoperative lower extremity assessed from insulin levels. A retrospective cohort study taken from secondary data from previous studies and their medical records at RSUP Dr. Mohammad Hoesin Palembang. Statistical analysis used STATA 15th edition. Wilcoxon showed that there was a significant difference in 0,125% bupivacaine group on insulin leves after 12th hours postoperative (p<0.05). Man-Whitney showed that there was no significant difference between the 0,125% bupivacaine with 3 mg morphine on insulin levels postoperative lower extremity after 6th hours, 6th and 12th hours and after 12th hours (p>0.05). In this study, there was no significant difference between the 0,125% bupivacaine with 3 mg morphine on insulin levels

COMPARISON OF COPPER LEVEL AND COLOR VISION IN PULMONARY TUBERCULOSIS PATIENTS BEFORE AND AFTER ETHAMBUTOL TREATMENT IN CATEGORY I AND II Devi Azri Wahyuni; Febria Restissa; Ahmad Rasyid; Erial Bahar
Majalah Kedokteran Sriwijaya Vol 52, No 2 (2020): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v52i2.11969

Copper as a metal chelator in ethambutol may interfere oxidative phosphorylation and mitochondrial function that are useful in the formation of ATP, so that long-term damage can cause apoptosis and interfere color vision. This study aims to determine the correlation between duration of ethambutol and copper levels in serum with color vision disorder examined with Farnsworth Munsell 100 Hue (FM100) in patients with tuberculosis. This study was an explorative observation of 20 samples during November 2017 - January 2018 period. Comparative analysis using independent t-test, paired t-test, Wilcoxon test and Mann-Whitney test, while correlation analysis using Spearman's test and Pearson's test. There was a significant difference of FM100value before and after in category I (p=0.000) with increase of total error value 11.80+5.31 or category II (p=0.000) with increase of total error value 15.00+7.41. There was significant difference of Cu2+ level before and after in category I (p=0.005) with decrease of Cu2+ level 15.57+5.04 mg/dL or category II (p=0.005) with decrease of Cu2+ level 31.66+7.35 mg/dL. The duration of Ethambutol was related to changes in color vision examined with FM100.

Benefits of domperidone in ambulatory acute diarrhea with severe vomiting Irene A. O.; Achirul Bakri; Erial Bahar; Rusdi Ismail
Paediatrica Indonesiana Vol 47 No 5 (2007): September 2007
Publisher : Indonesian Pediatric Society

Background Recently, most patients with diarrheal disease (DD)cases are hospitalized not due to severe dehydration, but due tosevere vomiting which interferes with fluid and food intake. Useof anti-vomiting medicines is not recommended because of itsâ€œcentralâ€ side effects. Domperidone has prokinetic and antiemeticeffects with only minimal extrapyramidal side effects.Objective To evaluate domperidone in preventing hospitalizationof DD patients in outpatient setting.Methods This randomized double blind, placebo-controlledclinical trial, was conducted from February to August 2005 atMohammad Hoesin Hospital, Palembang. We included patientsaged 6 to 59 months old with acute diarrhea who had vomited atleast 4 times in the last 24 hours, not in need of hospitalization,and agreed to participate. We excluded patients who had takenanti-vomiting drug, or those who had severe diseases, includingsevere malnutrition. The dose of domperidone was 1.25 mg per 5kg body weight.Results There were 183 subjects randomized, consisted of 91 whotook domperidone (treatment group) and 92 who took placebo(control group). The duration and decrease of vomiting frequencywere significantly different in favor of domperidone. Domperidoneprevented hospitalization significantly (P=0.001, OR=4.1, ARR= 20%, RRR=71%, NNT=5). No overt acute clinical side effectswere found.Conclusion Domperidone significantly shortened the duration anddecreased the frequency of vomiting in DD cases.

Benefits of gum arabic supplementation to oral rehydration solution in managing acute diarrhea Hasri Salwan; Isnada Isnada; Achirul Bakri; Rusdi Ismail; Erial Bahar
Paediatrica Indonesiana Vol 47 No 6 (2007): November 2007
Publisher : Indonesian Pediatric Society

Background Oral rehydration solution (ORS) has been provensuccessfully to overcome dehydration in diarrhea. The improvementof the effectiveness of ORS is still needed to overcome some failures.Gum Arabic (GA), an indigestable starch, can enhance ORSabsorption in mice with diarrhea. It is worthy to explore its benefitsin human. Since GA is non toxic to human being, it is regardedethical to conduct effectiveness study directly in clinical setting.Objective To evaluate the effectiveness of GA supplementationto ORS in managing inpatients diarrheal cases .Methods A double blind clinical trial was conducted during Marchto September 2004 in the Department of Child Health of M. HoesinHospital, Palembang. The subjects were randomly enrolled to GA-ORS (GA) group or ORS (SO) group. Indirect measurements wereconducted on ORS absorptive enhancement by evaluating theduration of diarrhea after hospitalization, frequency of defecationduring hospitalization, ORS consumption during hospitalization,and time laps of stool consistency conversion. The effectivenessanalysis was controlled for confounders.Results Supplementation of 0.5 gram GA to 200 ml ORS could decreasethe duration of diarrhoea 15.65 hours (P=0.000) during hospitalisation,frequency of defecation during hospitalization 1.171 times/days(P=0.002), ORS consumption 38.39 ml/kg BW (P=0.029), time ofstool consistency to become semisolid 15.84 hours (P=0.000), andbecome solid 14.45 hours (P=0.002). Vomiting during hospitalizationand aged group of 6-11 months were significant confounder. However,after controlling the outcome with these confounding factors, thebenefits of GA supplementation were still significant.Conclusions GA supplementation to ORS significantly shortenthe duration of diarrhea, decreases the frequency of defecation,consumption of ORS, time of stool consistency to becomesemisolid and solid in inpatients diarrheal cases.

RESULTS OF INTRAVENOUS ALINAMIN AND ALCOHOL EXAMINATION RESULTS IN PATIENTS COMPLAINTS OF SNACTING DISORDERS AT RSMH PALEMBANG Yoan Levia Magdi; Guntur Bayu Bima Pratama; Erial Bahar
JURNAL KEDOKTERAN DAN KESEHATAN Vol 10, No 2 (2023)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/JKK.V10I1.21350

Smell is a chemical substance mixed in the air that humans perceive with their sense of smell. Loss of smell or loss of smell has become very important in recent years. Currently, research on odor is very interesting because it can determine the type of odor, as well as the function of smell. Examination of the intravenous smell test and alcohol smell test is one of the gold standard examinations that can be done to determine the type of smell disorder. To determine the concordance between the results of the intravenous alinamin smell test and the alcohol smell test in patients with olfactory disorders at RSMH Palembang. Observational and analytic research using cross sectional. Data collection was carried out using the medical records of RSUP Dr. Mohammad Hoesin Palembang for the period October 2022 to January 2023. Data were analyzed with IBM SPSS 25. In this study, there were 49 patients with complaints of smell disturbances to the THTBKL department of RSUP Dr. Mohammad Hoesin Palembang. The mean age in the study was 33 years old with the most vulnerable population aged <20 years (26.5%). With the majority of the female sex (57.1%). While the majority of the work is mostly students (26.5%) and complains of gradual disturbance smells (91.8%). Most of the patients who came with complaints of smell disturbances were patients with sinonasal masses (53.1%). The correlation between intravenous alinamin and alcohol smell tests using the Spearman correlation test showed a very strong correlation (r=0.908) and in the conformity test using Cohen's kappa value obtained was 1.000 which means that perfect agreement was reached between the two tests. There is a concordance in the examination results between the alinamin smell test and the alcohol smell test in patients with complaints of smell disorders.

Relationship Between the Use of Topical Hypothermia with Ice Water to Postoperative Pulmonary Complications of Coronary Artery Bypass Graft Agustina, Sri; Gama Satria; Erial Bahar
Sriwijaya Journal of Surgery Vol. 7 No. 1 (2024): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v7i1.99

Introduction: Open heart surgery such as coronary artery bypass graft (CABG) is a heart surgery technique that uses a machine cardiopulmonary bypass (CPB) which can cause postoperative complications such as systemic inflammatory response syndrome (SIRS) and myocardial damage. Myocardial protection can be achieved through topical hypothermia techniques by lowering the heart temperature using a cold solution or ice cubes. Although several studies have shown its benefit in protecting the myocardium, the use of topical hypothermia remains controversial due to its uneven cooling effect and risk of tissue injury. This study aims to evaluate the relationship between the use of topical hypothermia of ice water and pulmonary complications of open heart surgery. Methods: This research is an analytical observational cohort retrospective comparison of pulmonary complications postoperatively in cardiac surgery patients who received systemic cardioplegia alone versus those who received a combination of systemic cardioplegia and topical hypothermia. Data collection was carried out using techniques consecutive sampling. Results: Of the 32 research subjects, the results of the analysis showed that the use of topical hypothermia did not have a statistically significant relationship (p>0.05) on the incidence of leukocytosis, pulmonary edema, duration of surgery, duration of ventilator use, duration of hospitalization, and mortality compared to the group that only received systemic cardioplegia. There was a significant relationship (p<0.05) between the incidence of pleural effusion in the topical hypothermia group. Conclusion: The use of topical hypothermia in cardiac surgery has a significant association with a higher incidence of pleural effusion.

Accuracy of the Chest Trauma Score (CTS) as a Predictor of Acute Respiratory Distress Syndrome (ARDS) in Blunt Chest Trauma Patients: Single Center Study at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia Peter, Billy; Arie Hasiholan Lumban Tobing; Erial Bahar
Sriwijaya Journal of Surgery Vol. 7 No. 2 (2024): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v7i2.104

Introduction: Chest trauma is the third most common cause of death due to trauma worldwide, with a mortality rate reaching 60%. Chest Trauma Score (CTS) is a chest trauma assessment score that can predict patient complications and death, including acute respiratory distress syndrome (ARDS). This study aims to determine the relationship and assess the accuracy of CTS as a predictor of ARDS in patients with blunt chest trauma. Methods: Medical records of 32 patients with blunt chest trauma were analyzed. Subjects were assessed for CTS, with components including age, number of rib fractures, presence of bilateral rib fractures, and lung contusion. Data were divided into two groups, CTS<5 and CTS≥5. Data were analyzed to determine the relationship between CTS and ARDS. Results: 62.5% of subjects had CTS ≥5 and 37.5% had CTS<5. As many as 68.8% of subjects with blunt chest trauma experienced ARDS. Analysis using the Fischer Exact Test showed that there was a significant relationship (p<0.05) between the CTS value and ARDS. The sensitivity of this study was 77.3%, specificity 70%, positive predictive value 85%, negative predictive value 58.3%. Conclusion: Statistically there is a significant relationship between the chest trauma score and ARDS, so the chest trauma score is considered accurate as a predictor of ARDS in patients with blunt chest trauma.

Analysis of Risk Factors for Continence Post Posterior Sagittal Anorectoplasty (PSARP) in Anorectal Malformation Patients: A Single Center Observational Study at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia Sinaga, Maleakhi Hasudungan; Shalita Dastamuar; Erial Bahar
Sriwijaya Journal of Surgery Vol. 7 No. 2 (2024): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v7i2.107

Introduction: Anorectal malformation (MAR) is a congenital abnormality with a significant incidence rate. Posterior sagittal anorectoplasty (PSARP) is the standard surgical procedure for MAR correction. However, achieving post-operative continence remains a major challenge. This study aims to identify risk factors associated with continence in MAR patients after PSARP at Dr. Mohammad Hoesin General Hospital Palembang. Methods: This prospective observational study involved MAR patients who underwent PSARP at Dr. Mohammad Hoesin General Hospital Palembang between January 2018 to December 2023. Demographic, clinical data, and RINTALA questionnaire results were collected. Statistical analysis was performed using a chi-square test, independent t-test, and logistic regression to identify significant risk factors associated with continence. Results: A total of 120 post-PSARP MAR patients met the inclusion criteria and participated in this study. The mean age of patients was 8.5 years (SD = 3.2). The results of the RINTALA questionnaire showed a mean score of 45.3 (SD = 12.8), with 42.5% of patients experiencing poor continence (RINTALA score < 40). Univariate analysis showed a significant association between poor continence and high MAR type (p = 0.002), age at PSARP < 1 year (p = 0.031), and the presence of a history of related surgery (p = 0.017). In multivariate analysis, MAR type was high (OR = 4.21; 95% CI: 1.54-11.52; p = 0.005) and age at PSARP < 1 year (OR = 2.87; 95% CI: 1, 05-7.89; p = 0.040) remained an independent predictor of poor continence. Conclusion: This study succeeded in identifying the type of MAR high and age at PSARP < 1 year as significant independent risk factors associated with poor continence in MAR patients after PSARP at Dr. Mohammad Hoesin General Hospital Palembang. These findings provide valuable information for surgeons and patient families in anticipating and managing post-PSARP continence problems.

Comparison of Upper Extremity Function After Operative and Non-operative Management of Distal Radius Intra-Articular Fractures with Clinical Assessment of QuickDASH Score Istiqomah, Ridnia Nur; Wiria Aryanta; Erial Bahar
Sriwijaya Journal of Surgery Vol. 7 No. 2 (2024): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v7i2.110

Introduction: Intra-articular fracture of the distal radius is a common injury and can disrupt upper extremity function. This study aims to compare upper extremity function after treatment of intra-articular distal radius fractures in productive age between operative and non-operative procedures using the QuickDASH score. Methods: This observational analytical study with a retrospective cohort design involved 80 patients with intra-articular distal radius fractures who were managed operatively (60 patients) and non-operatively (20 patients) at Dr. Mohammad Hoesin General Hospital Palembang. Data was collected from patient medical records and analyzed using the independent t-test and Chi-Square test. Results: The mean QuickDASH score in the operative group (10.53 ± 17.25) was significantly lower than the non-operative group (23.29 ± 23.82) (p = 0.012). There was a significant relationship between operative management and QuickDASH score (p = 0.023). Patients treated operatively were 1.5 times more likely to have normal upper extremity function (QuickDASH score ≤ 20). Conclusion: Operative treatment of intra-articular distal radius fractures in productive age provides better upper extremity functional outcomes compared to non-operative treatment, based on QuickDASH score assessment.

Co-Authors Achirul Bakri Agung Muda Patih Agustine Tinambunan Ahmad Rasyid Ahmat Umar Ari Dwi Prasetyo Arie Hasiholan Lumban Tobing Aswin Nugraha Awan Rochaniawan Belly Sutopo Wijaya Citra Dewi Denny Satria Utama Devi Azri Wahyuni Dwiandi Susilo Eddy Roflin Eriza Eva Syahriana Fadhli Aufar Kasyfi Febria Restissa Fifie Julianita Gama Satria Guntur Bayu Bima Pratama Hapzi Ali Harief Seamaladi Hasri Salwan Henny Sulastri Ika Kartika Indah Yunalda Iqmal Perlianta Irene A. O. IRWANSYAH Isnada Isnada Istiqomah, Ridnia Nur Jayawarsa, A.A. Ketut Jusuf Fantoni Krisna Murti Krisna Murti Linda Fatrisia Luther Theng Masdiyanto, Gayuh Prastya Mediarty Muhammad Asprianto Muhammad Hasnawi Haddani Muhlisa, Safitri Nafila Mahida Sukmono Nia Elisa Ginting Nur Riviati, Nur Nurul Salmah Alia Dita Olivia Amanda Peter, Billy R.M. Aerul Chakra Alibasya R.M. Faisal Reizkhi Fitriyana Rizki Bastari Rusdi Ismail Shalita Dastamuar Sinaga, Maleakhi Hasudungan Sri Agustina, Sri Sri Handayani Stefiyan, Ferdi Subandrate Sugiharto, Henry Surya Darma Theresia Christin Trijoso Permono Valendra, Deo Wiria Aryanta Yoan Levia Magdi Yovalina R Yulianto kusnadi Yundari, Yundari Yusril Yusril Zainal R

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