Article Per Year (5 Year)
p-Index From 2020 - 2025
2.293
P-Index
This Author published in this journals
All Journal HAYATI Journal of Biosciences Jurnal Neutrino : jurnal fisika dan aplikasinya MPI (Media Pharmaceutica Indonesiana) JC-T (Journal Cis-Trans): Jurnal Kimia dan Terapannya Jurnal Penelitian Pendidikan IPA (JPPIPA) Stigma : Jurnal Matematika dan Ilmu Pengetahuan Alam Unipa Pharmaceutical Sciences and Research (PSR) Jurnal Tumbuhan Obat Indonesia Jurnal Sains dan Kesehatan
Budipramana, Krisyanti
Department Of Pharmaceutical Biology, Faculty Of Pharmacy, University Of Surabaya, Surabaya 60293, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health

Published : 12 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : MPI (Media Pharmaceutica Indonesiana)

 1 
RP-HPLC Method Validation for Purity Assay of α-Mangostin Isolate Ratih, Ratih; Budipramana, Krisyanti; Firmansyah, Adang
MPI (Media Pharmaceutica Indonesiana) Vol. 5 No. 2 (2023): DECEMBER
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24123/mpi.v5i2.6108

Abstract

The quality of natural products regarding the purity of their active compounds, such as α-mangostin isolate from mangosteen pericarp, may vary depending on cultivation, harvest season, and isolation process. Thus, extensive isolation procedures are involved in obtaining a certain level of purity of the active compounds. Studies on the yield of α-mangostin isolate and its effectiveness as an active compound in health care have been reported. The quality parameter of the isolate as the intended active compound can be indicated by its purity level. Measuring the purity of the active compound is proposed to define the grade α-mangostin isolate as a starting material or even reference standard. The higher the purity level of α-mangostin isolate, the greater its potential as a reference standard candidate. Therefore, a selective analytical method is required to measure the purity level accurately. For this reason, a rapid analytical method to ensure α-mangostin isolate was developed and validated to confirm its purity. Separation condition semployed an X-Terra® C18 column 5 μm, 4.6 x 150 mm under an isocratic system with a mobile phase composition of MeCN:water (85:15) at a flowrate of 0.5 mL/ min and a detector wavelength of 243 nm were selected. Acceptable validation parameters of linearity in the range of 2.6 –52 μg/mL with r2 = 0,9994, Vx0 = 2.64%; accuracy 96.38 – 100.99%; precision 1.36%; and LOD/LOQ = 4.6 μg/mL/ 13.7μg/mL were achieved. The validated method was successfully applied to the purity assay α-mangostinisolate with a run time of less than 9 minutes.
Formulasi dan Evaluasi Sabun Wajah yang Mengandung Ekstrak Etanol Jamur Shiitake (Lentinus edodes) Putranti, Astridani Rizky; Wijaya, Yeremia Tanu; Budipramana, Krisyanti
MPI (Media Pharmaceutica Indonesiana) Vol. 6 No. 2 (2024): DECEMBER
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24123/mpi.v6i2.7032

Abstract

Jamur shiitake (Lentinus edodes) kaya akan polisakarida, selenium, dan vitamin sehingga banyak digunakan sebagai salah satu komposisi kosmetik kulit dan rambut. Salah satu kosmetik yang banyak menggunakan jamur shiitake adalah sabun wajah. Penelitian ini bertujuan untuk mengekstraksi jamur shiitake dengan beberapa konsentrasi alkohol, yaitu 96% (F1), 75% (F2), dan 50% (F3) menggunakan ultrasonik. Selanjutnya, formula tersebut dievaluasi karakteristik fisikokimianya meliputi pemeriksaan organoleptis, pH, berat jenis, daya sebar, uji busa, laju alir, dan uji hedonik. Formula terbaik adalah F3 dengan karakteristik warna putih krim, tekstur homogen, aroma enak, pH 10,55, berat jenis 0,25 g/ml, daya sebar 11,4 cm, stabilitas 100%, dan viskositas 233,8 cps. Uji hedonik formula F3 dilakukan terhadap 20 responden dengan parameter organoleptis, aroma, kekentalan, uji busa, dan efek melembabkan kulit. Hasil uji hedonik dari para responden dengan nilai tertinggi dari sabun wajah diperoleh dari parameter efek melembabkan kulit, diikuti dengan organoleptis dan efek busa. Shiitake mushrooms (Lentinus edodes) are rich in polysaccharides, selenium, and vitamins that are beneficial for skin and hair cosmetics. These compounds induce shiitake mushrooms to be wide­ly used as raw materials for cosmetics, one of which is facial wash. The purpose of this study is to extract shiitake mushroom using various ethanol concentration 96% (F1), 75% (F2), and 50% (F3) with ultra­sonic assisted extraction (UAE) method. Next, the formulas were evaluated for physicochemical characteristics, including organoleptic testing, pH, specific gravity, spreadability, foam test, flow properties, and hedonic test. F3 showed the best formula with evaluated characteristics of creamy white color, homogeneous texture, aromatic, pH value 10.55, specific gravity 0.25 g/ml, spreadability of 11.4 cm, 100% foam stability, and flow properties of 233.8 cps. Hedonic testing of F3 facial wash was conducted on 20 respondents with acceptance parameters including organoleptic, scent, viscosity, foam test, and moisturizing effect. The highest hedonic test result score was shown from the parameter of the ability of shiitake mushroom extract facial wash to moisturize the skin, followed by organoleptic and foam effect. Submitted: 12-11-2024, Revised: 09-12-2024, Accepted: 11-12-2024, Published regularly: December 2024
Co-Authors Adang Firmansyah Agustina, Astrid Karindra Amelia Lorensia Amilia, Eva Anita Purnamayanti Ayu Titisari, Manik Biutifasari, Verna Bramianto Setiawan Budi Pramana, Yanatra Djoko Adi Walujo Elfahmi Elfahmi, Elfahmi Fauziatul Fajaroh Frangky Sangande Huda, Miftakul Indah Nurhayati Marisca Evalina Gondokesumo, Marisca Evalina Marthy Meliana Ariyanti Jalmav Moira, Lovely Anastasia Pramana, Yanatra Budi Pratama, Anggara Martha Prihono Prihono, Prihono Putranti, Astridani Rizky Raharjo, Dian Natasya ratih ratih Rissyelly Rissyelly Setiawan, Vendra Subandowo, Marianus Sukrasno Sukrasno Suryadinata, Rivan Virlando Syaikhul Aziz Triono, Nathanel Wardani, Mariani Ika Wijaya, Yeremia Tanu Yanatra Budi Pramana Yitno Utomo Yodha, Agung Wibawa Mahatva Zulfikar Ainunsidiq, Mohammad