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All Journal Jurnal Riset Kesehatan Jurnal Penelitian Kesehatan Suara Forikes Health Notions Jurnal Analis Kesehatan JURNAL PENELITIAN KESEHATAN JURNAL MEDIA KESEHATAN INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Medicra (Journal of Medical Laboratory Science/Technology) Journal of Indonesian Medical Laboratory and Science (JoIMedLabS) AloHA International Journal of Health Advancement (AIJHA) International Journal of Advanced Health Science and Technology JHeS (Journal of Health Studies) Sewagati Analis Kesehatan Sains (e-Journal) Jurnal Pengabdian Kesehatan Beguai Jejama Frontiers in Community Service and Empowerment Health Dynamics Jurnal Teknokes
Handayati, Anik
Department Of Medical Laboratory Technology, Poltekkes Kemenkes Surabaya
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Health Notions

 1 
Correlation Between Implementation Intensity of Internal Quality Control and the Outcome of External Quality Control at Public Health Center Laboratories Anik Handayati; Ni Wayan Lisna Marheni
Health Notions Vol 5, No 3 (2021): March
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn50302

Abstract

Quality control is a process in a procedure conducted to evaluate testing process, with the purpose of ensuring the outcome of laboratory examinations, minimizing, as well as identifying the source of deviations. It consists of two, the internal and external quality control. This study aims to determine correlation between implementation intensity of internal quality control and the outcome of external quality control in the parameter of complete blood count in Public Health Centers Laboratories in Gianyar Bali. This study was a correlational observational study with cross-sectional approach. Total samples of 13 laboratories were taken from total population. As many as 15.38% of Public Health Center carried out internal quality control every day, 53.85% once a week, 7.7% biweekly, and 23.07% carried it out once a month. As for external quality control with parameter of complete blood count, 61.54% of the centers were good, 23.07% were average, and 15.38% were poor in handling abnormally low level of complete blood count. At normal level, 76.92% were good, 15.38% in average, and 7.7% were below average. At abnormally high level, 53.85% were good and 46.15% were in average. Statistical test results showed p-value >0.05. It can be concluded that there is no correlation between implementation intensity of internal quality control and the outcome of external quality control with parameter of complete blood count in Public Health Center laboratories in Gianyar Bali. Keywords: internal quality control; external quality control; complete blood count
Correlation of Neutrophil and Lymphocyte Counts in Patient Infected with Coronavirus (Covid-19) Nur Alina Hidayatur Rizki; Anik Handayati; Ellies Tunjung Sari Maulidiyanti
Health Notions Vol 6, No 3 (2022): March
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn60305

Abstract

Coronavirus Disease 2019 (Covid-19) causes hyper-inflammation and poor clinical conditions leading to high mortality in the world. Neutrophil and lymphocyte counts are used to describe disease severity in many clinical conditions including COVID-19. The purpose of this study was to determine the relationship between neutrophils and lymphocyte counts in patients infected with the coronavirus (Covid-19). The type of research used was cross-sectional. The sample in this study were patients infected with the Coronavirus (Covid-19) in a special isolation room who did a complete blood check at Brawijaya Hospital Surabaya. Types of data obtained from LIS (Laboratory Information System). The results of the study on the number of neutrophils in coronavirus (Covid-19) patients at Brawijaya Hospital showed an average neutrophil count of 5,174 cells/uL and an average lymphocyte count of 1,514 cells/uL. Data analysis showed that there was no correlation between the number of neutrophils and lymphocytes in patients infected with the Coronavirus (Covid-19) at Brawijaya Hospital Surabaya, possibly related to differences in immunity in each person. Keywords: coronavirus (Covid-19); neutrophils; lymphocytes
Anticoagulant Activity of Dayak Onion Bulb (Eleutherine bulbosa) Extract on Human Blood Samples Anik Handayati; Syamsul Arifin; Monica Putji Astuti
Health Notions Vol 5, No 2 (2021): February
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn50202

Abstract

Cardiovascular disease can occur due to disruption of the hemostatic system by forming blood clots in blood vessels, or commonly known as deep vein thrombosis. The curative action that has been carried out in the form of heparin anticoagulant administration had many side effects such as bleeding, hematuria, thrombocytopenia, and hypersensitivity; therefore, alternative anticoagulant ingredients such as onion bulbs have emerged. Dayak onion bulb (Eleutherine bulbosa) is known to contain eleutherinol compound, which has anticoagulant activity. This study aims to determine the potential anticoagulant activity of Dayak onion bulbs extract (Eleutherine bulbosa) on human blood samples. This anticoagulant activity test was carried out by observing the length of time for blood clotting in the extract treatment group with several concentrations (0, 10, 12.5, 16, 25, and 50%) by Clotting Time (Lee-White) method. The results showed a significant delay in blood coagulation time in the group treated with Dayak onion bulbs extract as increasing the concentration. About 50% Dayak onion onion bulb extract was showed a twofold increase in blood coagulation time thanthat of no extract administration. So that, Dayak bulb onion has the opportunity to be an alternative natural anticoagulant. Keywords: anticoagulants; Dayak onion bulbs (Eleutherine bulbosa); clotting time
Correlation of Fasting Blood Glucose Levels and HbA1c with Body Mass Index in Type 2 Diabetes Mellitus Patients Anik Handayati; Lully Hanni Endarini; Yuni Eka Cahyana
Health Notions Vol 6, No 4 (2022): April
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn60404

Abstract

Excess body mass index is at greater risk of developing diabetes mellitus than other diseases. Monitoring blood glucose includes through examination of fasting blood glucose levels and HbA1c. This study aims to find out the relationship of fasting blood glucose levels and HbA1c with Body Mass Index in type 2 diabetes mellitus patients. This study was an observational analytical study with a cross sectional design. The research was conducted at Prima Surabaya Main Clinic in January to June 2021. The sample was a type 2 diabetes mellitus patient who conducted fasting blood glucose examination, HbA1c and Body Mass Index measurement at Prima Surabaya Main Clinic as many as 40 people, were taken purposive sampling. The results of this study found that the average fasting blood glucose level of patients with type 2 diabetes mellitus was 172.6 mg / dL and HbA1c was 7.76%. The average Body Mass Index was 24.97. Pearson correlation test results obtained significant Body Mass Index with fasting blood glucose levels p = 0.150 and HbA1c with Body Mass Index p = 0.295, which means there is no relationship between fasting blood glucose levels and HbA1c with body mass index in type 2 diabetes mellitus patients.  Keywords: fasting blood glucose; HbA1c; Body Mass Index; auto analyzer
Design of Home Made Lyophilized Serum as a Control Material for Internal and External Quality Control in Clinical Laboratories Anik Handayati
Health Notions Vol 6, No 12 (2022): December
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn61203

Abstract

Important control materials are used to achieve laboratory test quality. Control materials can be obtained from commercial serum or can be made independently in the form of pooled serum. Control materials commonly used in clinical laboratories are commercial control materials in lyophilized form. However, the price is quite expensive, so it is less efficient to use in laboratories where the average number of examinations is small. Homemade lyophilized control agents can be used as an alternative to expensive factory controls. This study aims to analyze the stability of homemade lyophilized serum as a control material for the parameters of glucose, uric acid, cholesterol, triglycerides, BUN, creatinine, SGOT and SGPT stored for 7 months. This research was an experimental study with a time series research design conducted at the Clinical Chemistry Laboratory, Department of Medical Laboratory Technology, Poltekkes Kemenkes Surabaya, in January 2022 to September 2022. Blood serum was processed using the freeze dry technique to obtain a lyophilized form. Lyophilized serum was stored at 2-8°C in the freezer, dissolved using aquabides and checked every month, for 7 months. The results of glucose, uric acid, SGOT, SGPT, creatinine, cholesterol, and triglyceride tests did not cross the CV line (CCV). The Levey Jennings graph shows that the results of glucose, uric acid, SGOT, SGPT, creatinine, BUN, cholesterol, and triglycerides were in the mean ± 2 SD and did not follow Westgard's law restrictions, meaning that the results of homemade lyophilized serum were well controlled (in control) for 7 months of storage. It can be concluded that the homemade lyophilized serum is stable over 7 months of storage. 
Co-Authors ., Pestariati Alizah, Nur Amalia Putri Khurota Ayyun Amania, Salsabila Anggie Banowati Wibiseno Anita Dwi Anggraini Atsania Putri , Puji Lestari Ayu Puspitasari, Ayu Caesaria, Adela Candra Triana Hikma Christ Kartika Rahayuningsih Dewa Ayu Puja Satya Dinarta Diah Titik Mutiarawati Diah Titik Mutiarawati Edy Haryanto Edy Haryanto Edy Haryanto Ellies Tunjung Sari Maulidiyanti Endah Astuti Sri Sulami Endah Astuti, Sri Sulami Endarini, Lully Hanni Evy Diah Woelansari Fadia Rakhmalia Farah Adelia Qotrunnada Fitria Yulfirda Arini Fridayanti, Ni Made Risma Hapipah Hapipah Hikma , Candra Triana Ilma Ainun Nisa Jihan Azzahra Arsyi Juliana Christyaningsih Juliawan Apurwatama Kadek Profit Hartani Liliek Soetjiatie Luthfi Rusyadi Mamik Mamik Masdiva Putri Hidayah Maulida Azmi Wimasni Inah Minarti Minarti Mohd Nazil Salleh Monica Putji Astuti Museyaroh, Museyaroh Nada Nabilah Wulandari Ni Wayan Lisna Marheni Nur Alina Hidayatur Rizki Nur Vita Purwaningsih, Nur Vita Puji Lestari Atsania Putri Putri, Tiara Dewanti Rahayuningsih, Christ Kartika Rahmania, Adelia Prisma Retno Sasongkowati Rinza Rahmawati Samsudin Sri Sulami , Endah Astuti Sri Sulami Endah Astuti Sri Utami Suhariyadi Suhariyadi Suhariyadi Suhariyadi Suhariyadi Suhariyadi Suhariyadi Suliati Suliati Syamsul Arifin Syamsul Arifin Tjipto Rini Winarni Winarni Wisnu Istanto Yuni Eka Cahyana