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Handayati, Anik
Department Of Medical Laboratory Technology, Poltekkes Kemenkes Surabaya
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : International Journal of Advanced Health Science and Technology

 1 
Diagnostic test of Rapid antigen SARS Cov-2 against RT-PCR on suspected symptomatic COVID-19 patients at Rato Ebu Hospital Bangkalan Anik Handayati; Edy Haryanto
International Journal of Advanced Health Science and Technology Vol. 2 No. 3 (2022): June
Publisher : Forum Ilmiah Teknologi dan Ilmu Kesehatan (FORITIKES)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/ijahst.v2i3.3

Abstract

COVID-19 is caused by the SARS-CoV-2 virus. Two tests to detect the SARS-CoV-2 virus are the rapid antigen test and RT-PCR. The gold standard for testing for COVID-19 is RT-PCR. The high number of Covid-19 sufferers in Madura plus the RT-PCR examination takes a long time. Rapid antigen examination is one of the Covid-19 screening solutions that should be tested because it offers fast examination times. This study aims to determine the sensitivity and specificity of the SARS COV-2 rapid antigen test to RT PCR for the diagnosis of COVID 19. This type of research is an analytical study with a cross-sectional design. The study was conducted at Rato Ebu Hospital Bangkalan from July-September 2021. The sample of this study was suspected symptomatic COVID-19 patients who were examined using the SARS-CoV-2 rapid antigen and RT-PCR using purposive sampling of as many as 60 people. Diagnostic test method by measuring the sensitivity and specificity of rapid antigen to RT-PCR. Based on the results of the study, it can be concluded that the sensitivity of the SARS Cov-2 Rapid Antigen to RT-PCR is 82.97% and the specificity of the SARS Cov-2 Rapid Antigen to RT-PCR is 100%.
Description of Platelet Count Patients Infected with Corona Virus (Covid-19) with Grouping of Productive and Elderly Age Hapipah Hapipah; Anik Handayati; Nur Vita Purwaningsih
International Journal of Advanced Health Science and Technology Vol. 2 No. 1 (2022): February
Publisher : Forum Ilmiah Teknologi dan Ilmu Kesehatan (FORITIKES)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (146.272 KB) | DOI: 10.35882/ijahst.v2i1.2

Abstract

Routine hematology tests are one of the supporting tests in diagnostics to assess the severity of the disease and predict risk in COVID-19 patients, and can be used as supporting data on RT-PCR tests. Some blood tests that are widely used as monitoring tools and predicators of COVID-19 are the number of leukocytes, the  number of lymphocytes, the number of neutrophils, the  number of platelets and NLR (Neutrophil lymphocyte ratio).  Thrombocytopenia occurs due to excessive use of tromocytes in the body as compensation for damage to lung parenchym cells, the lungs are organs where platelets are released from megacaryocytes, so this damage causes disruption of platelet maturation process. The type of research used is quantitative descriptive with the aim to find out the results of blood tests complete with platelet parameters in patients infected with the COVID-19 coronavirus at Muhammad Noer Pamekasan General Hospital. The results of the study were platelet count test results at normal productive age of 67 respondents (96%) and decreased platelet count (Thrombocytopenia) by 3 respondents (4%). While in normal elderly age a number of 26 respondents (87%) and a decreased platelet count (Thrombocytopenia) amounted to 4 respondents (13%).
Analysis of Images of Neutrophil Lymphocyte Ratio and Bacteria Density Level of Helicobacter Pylori in Tissue in Gastritis Patients Fadia Rakhmalia; Anik Handayati; Evy Diah Woelansari; Mohd Nazil Salleh
International Journal of Advanced Health Science and Technology Vol. 2 No. 6 (2022): December
Publisher : Forum Ilmiah Teknologi dan Ilmu Kesehatan (FORITIKES)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/ijahst.v2i6.181

Abstract

Gastritis is an inflammatory disease that can last for a long time. Helicobacter pylori infection is known as the main cause of peptic ulcer and the most common cause of gastritis. Helicobacter Pylori infection will cause mononuclear (MN) and polymorphonuclear (PMN) cell infiltration and will increase the production of proinflammatory cytokines in the gastric mucosa compared to non-Helicobacter Pylori gastritis. Helicobacter Pylori with histopathological examination diagnosis. This type of research is descriptive observational with purposive sampling data collection technique at the Anatomical Pathology Laboratory Installation, RSPAL dr. Ramelan Surabaya. The data used are the results of a biopsy of 60 samples that were determined as gastritis with histopathological examination of the identification of Helicobacter Pylori bacteria in gastric tissue classified by the level of bacterial density using The Updated Sydney System, as well as haemogram data for complete blood examination to further calculate the neutrophil lymphocyte ratio (NLR). The data were processed using descriptive statistical tests to determine the average neutrophil lymphocyte ratio (NLR). Based on the statistics of the r-Spearman test, the density of Helicobacter Pylori, (Pν = 0.000) below < 0.005 indicates that there is a strong relationship between the neutrophil lymphocyte ratio (NLR) and the density of Helicobacter Pylori bacteria.
The Comparison of Variant Index Score (VIS) of Homemade and Commercial Lyophilized Serum Ilma Ainun Nisa; Amalia Putri Khurota Ayyun; Anik Handayati; Museyaroh; Diah Titik Mutiarawati
International Journal of Advanced Health Science and Technology Vol. 3 No. 6 (2023): December
Publisher : Forum Ilmiah Teknologi dan Ilmu Kesehatan (FORITIKES)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/ijahst.v3i6.283

Abstract

Many laboratory installations have not implemented quality assurance periodically due to the high cost of purchasing control materials. This study aims to determine the difference in Variant Index Score value of homemade lyophilized serum with commercial parameters of SGOT, SGPT, creatinine, BUN, glucose, uric acid, triglycerides, and cholesterol. The research was conducted in January–May 2023 at the Surabaya Health Center laboratory, the reference laboratory, and the Ubaya Technobiology Faculty using descriptive comparative research with a quantitative approach. The test material used was homemade lyophilized serum, with the research variable being the VIS value of lyophilized serum. The results of the analysis showed a comparison of the VIS value of homemade and commercial serum based on the participant's target values of SGOT, SGPT, creatinine, BUN, glucose, triglycerides, and cholesterol parameters obtained a significance value of 00,759; 0,983; 0,160; 0,994; 0,413; 0,797; 0,318; and 0,262, and based on the true value target values of SGOT, SGPT, creatinine, BUN, glucose, uric acid, triglycerides, and cholesterol parameters obtained a significance value of 0,70; 0,973; It is concluded that there is no significant difference in VIS value between homemade and commercial lyophilized serum, so homemade lyophilized serum can be used as an option for control material to replace commercial serum for laboratory quality assurance.
Compatibility Between Platelet Histogram with IP Message and Platelet Morphology in Thrombocytopenia Patients Dewa Ayu Puja Satya Dinarta; Anik Handayati; Syamsul Arifin
International Journal of Advanced Health Science and Technology Vol. 3 No. 6 (2023): December
Publisher : Forum Ilmiah Teknologi dan Ilmu Kesehatan (FORITIKES)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/ijahst.v3i6.292

Abstract

The aim of this study was to evaluate the compatibility of platelet histogram results with IP Message on the hematology analyzer Sysmex XN-1000 for the platelet morphology of peripheral blood smears of thrombocytopenia patients. This was a quantitative descriptive study of 54 samples taken using the saturation sampling technique at Grati Pasuruan Hospital from April 1–30 2023. The results showed that the histograms that often appeared were abnormal heights on the PU Flag and the IP Messages that often appeared were “PLT Clumps?”, “PLT Abn Distribution”, and “Thrombocytopenia”, with a compatibility level of platelet morphology on peripheral blood smear examination reaching 90.7%. The study concluded that there was a high compatibility between the platelet histogram results accompanied by the IP Message and the platelet morphology of the peripheral blood smear of thrombocytopenia patients, which could improve the accuracy and efficiency of platelet count examination.
Co-Authors ., Pestariati Alizah, Nur Amalia Putri Khurota Ayyun Amania, Salsabila Anggie Banowati Wibiseno Anita Dwi Anggraini Atsania Putri , Puji Lestari Ayu Puspitasari, Ayu Caesaria, Adela Candra Triana Hikma Christ Kartika Rahayuningsih Dewa Ayu Puja Satya Dinarta Diah Titik Mutiarawati Diah Titik Mutiarawati Edy Haryanto Edy Haryanto Edy Haryanto Ellies Tunjung Sari Maulidiyanti Endah Astuti Sri Sulami Endah Astuti, Sri Sulami Endarini, Lully Hanni Evy Diah Woelansari Fadia Rakhmalia Farah Adelia Qotrunnada Fitria Yulfirda Arini Fridayanti, Ni Made Risma Hapipah Hapipah Hikma , Candra Triana Ilma Ainun Nisa Jihan Azzahra Arsyi Juliana Christyaningsih Juliawan Apurwatama Kadek Profit Hartani Liliek Soetjiatie Luthfi Rusyadi Mamik Mamik Masdiva Putri Hidayah Maulida Azmi Wimasni Inah Minarti Minarti Mohd Nazil Salleh Monica Putji Astuti Museyaroh, Museyaroh Nada Nabilah Wulandari Ni Wayan Lisna Marheni Nur Alina Hidayatur Rizki Nur Vita Purwaningsih, Nur Vita Puji Lestari Atsania Putri Putri, Tiara Dewanti Rahayuningsih, Christ Kartika Rahmania, Adelia Prisma Retno Sasongkowati Rinza Rahmawati Samsudin Sri Sulami , Endah Astuti Sri Sulami Endah Astuti Sri Utami Suhariyadi Suhariyadi Suhariyadi Suhariyadi Suhariyadi Suhariyadi Suliati Suliati Syamsul Arifin Syamsul Arifin Tjipto Rini Winarni Winarni Wisnu Istanto Yuni Eka Cahyana