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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Sewagati Journal of Medicine and Health Technology
Sari, Desiana Widityaning
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Arts Humanities Biochemistry, Genetics & Molecular Biology Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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The Confusion between Pustular Psoriasis and Acute Generalized Exanthematous Pustulosis as a Cause of Exfoliative Dermatitis: A Case Report Sari, Desiana Widityaning; Damayanti, Damayanti; Anggraeni, Sylvia; Umborowati, Menul Ayu; Cita Rosita Sigit Prakoeswa; Ervianti, Evy
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 3 (2021): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.3.2021.224-231

Abstract

Background: Pustular psoriasis and Acute Generalized Exanthematous Pustulosis (AGEP) are grouped under pustular diseases, in which their clinical manifestations are similar. Those diseases can lead to exfoliative dermatitis. Purpose:To evaluate a specific histopathological examination in differentiating Pustular Psoriasis and AGEP. Case: A 55-year-old woman presented with sudden redness and diffused scaly skin with multiple pustules and also fever. She had taken Cefadroxil 2 days before the scales and pustules appeared. Leukocytosis and histopathological examination results from biopsy supported the diagnosis of AGEP. The patient was then hospitalized and received steroid therapy. Within the first week of tapering off, the scales disappeared but the pustules increased. After such clinical findings, the histopathological examination results were revisited and reassessed. Thus, we considered changing the diagnosis to Pustular Psoriasis, and the therapy was switched to Methotrexate. The patient had a better outcome, and the pustules slowly disappeared entirely. Discussion: It is often difficult to differentiate between the pustules in pustular psoriasis and AGEP unless by thorough history-taking and physical examinations. AGEP is characterized by a widespread of pustules with an acute febrile onset; while pustular psoriasis is an acute variant of psoriasis where pustules are spread over erythematous skin and accompanied by high fever and leukocytosis. Conclusion: Histopathological examination is the gold standard for the establishment of pustular psoriasis diagnosis. The histopathological characteristics of pustular psoriasis and AGEP are difficult to differentiate. Therefore, we need detailed history-taking and physical examination to establish the diagnosis.
Pelatihan Psychological First Aid (PFA) dan Stress Management untuk Mahasiswa Kedokteran Tahun Pertama FKK ITS 2024 Syulthoni, Zain Budi; Haykal, Muhammad Nazhif; Eljatin, Dwinka Syafira; Haque, Sayidah Aulia Ul; Rangkuti, Rahmah Yasinta; Fadhlina, Afia Nuzila; Indriastuti, Endah; Radiansyah, Riva Satya; Putri, Atina Irani Wira; Sari, Desiana Widityaning; Indriani, Ratri Dwi; Siswanto, Putri Alief; Mahdi, Faizal
Sewagati Vol 9 No 1 (2025)
Publisher : Pusat Publikasi ITS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12962/j26139960.v9i1.2413

Abstract

Mahasiswa kedokteran tahun pertama menghadapi banyak tantangan dalam menye-suaikan diri dengan lingkungan akademik baru, yang dapat memengaruhi kesehatan mental mereka. Tujuan dari penelitian ini adalah untuk meningkatkan kemampuan siswa dalam mengelola stres dan memberikan dukungan psikologis melalui pelatihan manajemen stres dan dukungan psikologis pertama / Psychological First Aid (PFA). 30 mahasiswa kedokteran semester 1 FKK ITS mengikuti pelatihan, yang berlangsung selama dua hari dan total 16 jam. Pelatihan juga dievaluasi melalui pretest dan posttest menggunakan kuesioner. Melalui simulasi kasus, peserta menunjukkan kemampuan yang baik dalam menggunakan strategi PFA dan manajemen stres. Hasil analisis menunjukkan peningkatan signifikan dalam pemahaman dan keterampilan peserta setelah mengikuti pelatihan (p=0.000). Pelatihan mencakup pemaparan teori dan praktik keterampilan PFA, seperti keterampilan mendengarkan yang aktif, keterampilan komunikasi, keterampilan empati, dan keterampilan bertahan hidup. Dua modul program ber-ISBN dan publikasi di media massa. Kesimpulan dari pengabdian masyarakat adalah bahwa terjadi peningkatan pemahaman dan kemampuan mahasiswa kedokteran tahun pertama terhadap Psychological First Aid dan Stress Management yang diharapkan lebih siap menghadapi tantangan akademik.
Successful Management of High-Risk Pregnancy with TORCH Infection History and Chronic Hypertension Karimah, Rumman; Fadli, Sonny; Eljatin, Dwinka Syafira; Indriastuti, Endah; Sari, Desiana Widityaning; Ridhoi, Ahmad
Journal of Medicine and Health Technology Vol. 1 No. 2 (2024)
Publisher : Direktorat Riset dan Pengabdian Kepada Masyarakat, Institut Teknologi Sepuluh Nopember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12962/j30466865.v1i2.1129

Abstract

A 41-year-old pregnant woman of Javanese ethnicity attended the outpatient clinic of a private hospital, presented with fifth pregnancy and no living children due to a history of ectopic pregnancy, two times IUFD, and one time neonatal death. The patient also had a history of chronic hypertension and asthma. The examination showed positive IgG Toxoplasma and CMV antibody levels. The patient's blood pressure also never touched the normal limit since the beginning of pregnancy. At the end of pregnancy, she had very high blood pressure and proteinuria. According to WHO Maternal Mortality Rate (MMR) is still very high, where two of the five highest causes are infection and hypertension in pregnancy. High risk pregnancies require special attention in monitoring during pregnancy and management. In a history of bad obstetrical history it is necessary to screen for infection which can be done by antibody serology testing. A positive IgG indicates immunity to the virus, if possible it is necessary to check IgG Avidity to determine whether therapy is still needed or can rely on the immune system that has been formed. Chronic hypertension (Systolic Blood Pressure (SBP) > 140 mmHg and / or Diastolic Blood Pressure (DBP) > 90 mmHg since < 20 Weeks Gestational Age (WGA) until 42 days after delivery). First-line Labetalol and Nifedipine or second-line Methyldopa and Hydrochlorothiazide should be considered depending on the condition and gestational age. If there are signs of preeclampsia, termination should be done if possible, along with antihypertensives and anticonvulsants such as MgSO4.
The Role of Microbiota in Atopic Dermatitis Sari, Desiana Widityaning; Nugraheningtyasari, Nur Annisa
Journal of Medicine and Health Technology Vol. 2 No. 2 (2025)
Publisher : Direktorat Riset dan Pengabdian Kepada Masyarakat, Institut Teknologi Sepuluh Nopember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12962/j30466865.v2i2.2630

Abstract

Skin microbiota play an important role in the pathogenesis of AD. Damage to the integrity of the skin mucosa allows penetration of allergens and colonization of the skin by pathogenic microorganisms. This can then stimulate inflammation related to excessive activation of Th2 lymphocytes throughout the body including the digestive tract and respiratory tract. The understanding of the latest definition of AD emphasizes this disease as a chronic inflammatory disease characterized by disruption of the skin barrier, inflammation, and dysbiosis (an imbalance between commensal and pathogenic bacteria, which then has significant health implications). Skin dysbiosis is based on an increase in the concentration of Staphylococcus aureus colonization, which causes a decrease in the number of commensal bacteria. Changes in the microbiota in AD affect the functioning of the immune system, stimulating inflammatory reactions that are manifested as atopic eczema. This concept of dysbiosis is important to discuss because it can influence new strategies for the treatment and prevention of AD. This article will further discuss the role of microbiota in AD.
Co-Authors Anggraeni, Sylvia Cita Rosita Sigit Prakoeswa Damayanti Damayanti Dwinka Syafira Eljatin Evy Ervianti Fadhlina, Afia Nuzila Fadli, Sonny Haque, Sayidah Aulia Ul Haykal, Muhammad Nazhif Indriani, Ratri Dwi Indriastuti, Endah Indriastuti, Endah Karimah, Rumman Mahdi, Faizal Menul Ayu Umborowati, Menul Ayu Nugraheningtyasari, Nur Annisa Putri Alief Siswanto Putri, Atina Irani Wira Radiansyah, Riva Satya Rangkuti, Rahmah Yasinta Ridhoi, Ahmad Syulthoni, Zain Budi