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PROFIL KEMAMPUAN LITERASI ANAK KELAS 3 SEKOLAH DASAR DI SURAKARTA Afkarina, Izza; Sutanto, Alfiani Vivi; Wiliyanto, Dian Atnantomi
Jurnal Review Pendidikan dan Pengajaran Vol. 7 No. 4 (2024): Special Issue Vol. 7 No. 4 Tahun 2024
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jrpp.v7i4.38802

Abstract

Keterampilan literasi di sekolah dasar menjadi langkah awal yang krusial untuk mencapai keberhasilan dalam proses pembelajaran yang produktif. Penelitian ini bertujuan untuk mendeskripsikan profil kemampuan literasi anak kelas 3 sekolah dasar di Surakarta dan faktor yang mempengaruhi peningkatan literasi. Penelitian ini menggunakan mixed methods dengan data kuantitatif dan kualitatif yang diperoleh melalui tes dan wawancara. Sampel penelitian terdiri dari 30 siswa yang dipilih menggunakan teknik quota sampling. Instrumen yang digunakan meliputi tes pemahaman membaca, penilaian menulis, dan pemeriksaan kemampuan mengeja. Teknik analisis data adalah analisis deskriptif kuantitatif dan kualitatif. Hasil penelitian menunjukkan bahwa kemampuan literasi siswa kelas 3 sekolah dasar di Surakarta didominasi pada kategori sedang berdasarkan dari penilaian pemahaman membaca, menulis, dan mengeja. Adapun faktor yang mempengaruhi literasi adalah strategi pengajaran guru, jenis bacaan, jenis tulisan, program literasi, dan ketersediaan fasilitas. Tantangan yang dihadapi guru dalam mengajar literasi yaitu kebiasaan siswa yang selalu di bimbing, kurangnya keterlibatan orang tua, perbedaan kemampuan kognitif siswa.
Network pharmacology approach to identifying optimal therapeutic targets in cancer drug discovery and development: Bibliometric analysis and scoping review Rovik, Anwar; Henra, Henra; Rahman, Farras Alifia; Afkarina, Izza; Conara, Flafiani Cios
Indonesian Journal of Pharmacology and Therapy Vol 7 No 1 (2026)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.13076

Abstract

A rise in chronic diseases, including cancer, increasingly strains public health. While conventional drug discovery often focuses on single molecules, this method frequently fails to address complex diseases with multiple causes. Network pharmacology, a systems biology approach, provides a more complete understanding of disease mechanisms by analyzing intricate biological networks. By combining multi-omics data and computational models, network pharmacology helps identify new drug targets and cellular pathways. This approach is especially promising in cancer research, where it can reveal complex interactions between genes, proteins, and metabolites. This review explains the principles of network pharmacology and its use in cancer drug discovery. We cover the process, from network building and analysis to experimental testing. Additionally, we examine how network pharmacology can speed up the development of personalized cancer treatments.
Network pharmacology approach to identifying optimal therapeutic targets in cancer drug discovery and development: Bibliometric analysis and scoping review Rovik, Anwar; Henra, Henra; Rahman, Farras Alifia; Afkarina, Izza; Conara, Flafiani Cios
Indonesian Journal of Pharmacology and Therapy Vol 7 No 1 (2026)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.13076

Abstract

A rise in chronic diseases, including cancer, increasingly strains public health. While conventional drug discovery often focuses on single molecules, this method frequently fails to address complex diseases with multiple causes. Network pharmacology, a systems biology approach, provides a more complete understanding of disease mechanisms by analyzing intricate biological networks. By combining multi-omics data and computational models, network pharmacology helps identify new drug targets and cellular pathways. This approach is especially promising in cancer research, where it can reveal complex interactions between genes, proteins, and metabolites. This review explains the principles of network pharmacology and its use in cancer drug discovery. We cover the process, from network building and analysis to experimental testing. Additionally, we examine how network pharmacology can speed up the development of personalized cancer treatments.