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Acute Kidney Injury as Predictor of Major Adverse Cardiac Event (MACE) in 3 Months after Admission of Acute Heart Failure Patients in Haji Adam Malik General Hospital Medan Chan, Muhammad Ikhsan; Andra, Cut Aryfa; Raynaldo, Abdul Halim; Hasan, Harris; Sarastri, Yuke; Sitepu, Andika
Cardiovascular and Cardiometabolic Journal (CCJ) Vol. 5 No. 2 (2024): Cardiovascular and Cardiometabolic Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ccj.v5i02.2024.82-94

Abstract

Highlights: 1. This study provides novel evidence that acute kidney injury (AKI) is a strong predictor of major adverse cardiovascular events (MACE) in patients with acute heart failure, highlighting the critical need for early detection and intervention to improve outcomes. 2. This research underscores the importance of incorporating kidney function assessment into the comprehensive management of acute heart failure patients. - Background: Acute heart failure is a condition with high morbidity and mortality. Decreased renal function after hospitalization is a predictor of longer hospitalization and increased mortality. Patients with acute renal failure, especially injury or failure grade, have a worse long-term prognosis compared to patients without acute renal failure, which will lead to MACE. Major adverse cardiovascular events are a combination of non-fatal stroke, non-fatal myocardial infarction, or cardiovascular death. Material and Methods: This study was a retrospective cohort study of 159 patients with acute heart failure at HAM General Hospital from April 1, 2023 to December 31, 2023. Electrocardiographic, laboratory, and echocardiographic data were collected. Patients were categorized according to RIFLE classification and monitored to see MACE in the samples. Bivariate tests were performed to see the correlation between samples. Furthermore, Kaplan-Meier curves were analyzed to see the survival rate. Results: Total subjects were 159 patients consisting of 98 acute heart failure patients with AKI and 61 heart failure patients without AKI. There was a correlation between heart failure patients who developed acute renal failure and the number of days of hospitalization (p = 0.000), in hospital mortality (p = 0.002), rehospitalization in less than 3 months (p = 0.000), and mortality in less than 3 months (p = 0.001). Conclusion: Acute kidney injury has a correlation with MACE so that it can be a predictor of major cardiovascular events in patients with acute heart failure.
Early detection of subclinical rheumatic heart disease through echocardiographic screening: a study in North Sumatra, Indonesia Ardini, Tengku Winda; Ilyas, Kamal Kharazzi; Nasution, Ali Nafiah; Ketaren, Andre Pasha; Napitupulu, Bertha Gabriella; Batubara, Gio Justisia; Sarastri, Yuke; Raynaldo, Abdul Halim; Siregar, Abdullah Afif; Siregar, Yasmine Fitrina; Dewita, Auliya; Andra, Cut Aryfa; Lubis, Anggia Chairuddin
Heart Science Journal Vol. 5 No. 3 (2024): The Science and Art of Revascularization in Acute Coronary Syndrome
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.03.10

Abstract

BACKGROUND: Given the urgent need to address the significant morbidity and mortality associated with Rheumatic Heart Disease (RHD) in Indonesia, there is a growing interest in exploring cost-effective screening approaches, such as handheld echocardiography.OBJECTIVES: The purpose of this study was to ascertain the prevalence of RHD in North Sumatra, Indonesia.METHODS: This descriptive observational study was conducted within the population of North Sumatra from 2022 to 2023. Junior high school students aged 12 to 15 years were included from randomly selected schools in Langkat, Tebing Tinggi, and Labuhan Batu. Data collection encompassed various parameters, including social demographic information, parental characteristics, environmental factors, household details, anthropometric measurements, physical assessments, auscultation findings, and echocardiographic data. The data were analyzed descriptively.RESULTS: In our study, a total of 692 children were examined, with an average age of 12.9 years and a standard deviation of 1.1 years, among whom 42.5% were male. Utilizing echocardiographic evaluations, we identified RHD in four children, yielding a prevalence rate of 0.6%. Further examination of these cases revealed that the majority, accounting for three individuals (75%), exhibited borderline RHD, while one child (25%) presented with definite RHD.CONCLUSION: In our study population, the prevalence of RHD was 0.6%. A broader echocardiographic screening program is necessary to determine the overall prevalence of RHD, assess the disease burden, and identify individuals earlier to prevent adverse outcomes.
Alteration of Right Ventricular-Pulmonary Arterial Coupling Before and After Decongestion in Non-Preserved Fraction Acute Heart Failure Patients at Adam Malik Hospital Medan Brahmana, Andrew Timanta; Ketaren, Andre Pasha; Andra, Cut Aryfa; Lubis, Anggia Chairuddin; Haykal, Teuku Bob; Siregar, Yasmine Fitrina; Lubis, Hilfan Ade Putra; Purba, Joy Wulansari; Akbar, Nizam Zikri
Journal of Society Medicine Vol. 4 No. 1 (2025): January
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v4i1.190

Abstract

Objective: To assess whether there is right ventricular-pulmonary artery (RV-PA coupling by tricuspid annular plane systolic excursion/pulmonary artery systolic pressure TAPSE/PASP) changes in determining the clinical results of decongestion in patients with acute heart failure (AHF) with non-preserved ejection fraction (non-HFpEF) before and after decongestive at Adam Malik Hospital Medan. Methods: This study is an observational study with a prospective approach and consecutively collected, in patients AHF with non-HFpEF at Adam Malik Hospital Medan in the period from September 2023 until November 2024d. The sample is an eligible population that meets the inclusion and exclusion criterias. Results: This study consisted total 44 subjects with majority of 37 men (75%), an average age of 61 years old. A total of 28 subjects (63.6%) had hypertension as comorbid. There were 33 people (75%) who had sinus rhythm. The most acute heart failure phenotype commonly found was acute decompensated heart failure (ADHF) with 21 subjects. The longest length of stay AHF was cardiogenic shock with a median of 9 days. A significant decrease in median heart (p 0.0001), tricpuspid valve gradient (TVG) examination showed a significant decrease in (p 0.0001), PASP examination had a significant decrease in the average (p 0.0001), RV-PA coupling showed a significant increment (p 0.0001). A significant relationship was found between RV-PA coupling changes and decongestion in all acute heart failure groups (p 0.005). No significant relationship between RV-PA coupling ratio with length of stay was found. Conclusion: There were differences found in RV-PA coupling as increment with significant value in complete and partial decongestion groups, with a RV-PA coupling cut-off value of 0.65 and sensitivity and specificity of 68.8% and 67.9%, respectively.
Relationship between Coronary Artery Calcium Score (CACS) and Diastolic Dysfunction in Patients with Stable Coronary Heart Disease at Adam Malik General Hospital Medan Putra, Muhammad Hafiz Mahruzza; Hasan, Refli; Sitepu, Andika; Hasan, Harris; Ketaren, Andre Pasha; Andra, Cut Aryfa; Raynaldo, Abdul Halim; Ilyas, Kamal Kharrazi
Journal of Society Medicine Vol. 4 No. 6 (2025): June
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v4i6.221

Abstract

Introduction: Coronary artery calcium score (CACS) is a specific indicator of coronary atherosclerosis that plays a role in assessing the degree of calcification in atherosclerosis. Diastolic function is the first aspect of cardiac function to be impaired in ischemic heart disease. This study aims to determine the relationship between calcium scoring and diastolic dysfunction. Methods: This analytical observational study with cross-sectional design evaluated the relationship between coronary artery calcium score (CACS) and left ventricular diastolic function in patients with stable CAD. Data were collected retrospectively from medical records at RSUP H. Adam Malik Medan during Nov 2023-Nov 2024. CACS was assessed using coronary CT scan, while left ventricular diastolic function was measured by echocardiography. Data analysis used chi-square test, Mann-Whitney U test, and ROC curve analysis to evaluate CACS threshold in predicting diastolic dysfunction. Results: Among 158 analyzed samples, 113 patients had diastolic dysfunction. A calcium score ≥100 was found in 46.2% of patients, showing 1.318 times higher risk of diastolic dysfunction versus those with scores <100 (p = 0.006; 95% CI 1.083–1.605). ROC analysis showed CACS had moderate predictive ability for diastolic dysfunction with AUC of 0.647 (p = 0.004). A calcium score threshold of 45 had 65.5% sensitivity and 62.2% specificity in detecting diastolic dysfunction. Type 2 diabetes mellitus, urea, and creatinine levels were also significantly associated with diastolic dysfunction (p < 0.05). Conclusion: Calcium score shows a significant relationship with diastolic dysfunction in stable CAD patients and can predict diastolic dysfunction in patients undergoing coronary CT scan.
Incidence of Bleeding Complications in Acute ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention Ferhat, Muhammad; Lubis, Anggia Chairuddin; Safri, Zainal; Mukhtar, Zulfikri; Hasan, Harris; Haykal, Teuku Bob; Siregar, Yasmine Fitrina; Andra, Cut Aryfa
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 3 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i3.21143

Abstract

Background: This study aims to comprehensively describe the incidence, types, and associated risk factors of bleeding complications in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI), addressing a critical gap in the literature given the global burden of cardiovascular disease and the inherent bleeding risks of contemporary antithrombotic therapies. Methode: This retrospective cross-sectional study will investigate the incidence and types of bleeding complications, along with associated risk factors, in ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PPCI) at Adam Malik Hospital Medan, analyzing data from May 2022 to December 2024 through ethical review and statistical analysis using SPSS version 23. Result: Of 245 STEMI patients undergoing primary PCI, 42.9% experienced bleeding, predominantly minor (BARC 1 and 2, 94.2% combined), with significant associations observed between bleeding and lower hemoglobin, higher leukocyte and creatinine levels, higher TIMI score, Killip class 3 and 4, diabetes, use of maintenance heparin, and increased mortality (84.6% of all deaths occurred in bleeding patients), while hematuria and puncture site hematoma were the most common bleeding sources. Conclusion: This study found that 42.9% of 245 STEMI patients undergoing primary PCI experienced bleeding complications, predominantly minor (94.2%), with an average age of 55.22 years and a male majority. Keyword: Bleeding complications, Acute Coronary Syndrome (ACS), ST-Elevation Myocardial Infarction (STEMI), Primary Percutaneous Coronary Intervention (PPCI)
Patient-reported perceptions of life quality and longevity in chronic heart failure Lubis, Ahmad Feriansyah; Lubis, Anggia Chairuddin; Andra, Cut Aryfa; Raynaldo, Abdul Halim; Ardini, Tengku Winda; Haykal, Teuku Bob; Sarastri, Yuke
Heart Science Journal Vol. 6 No. 4 (2025): The Pursuit of Precision: Navigating Risks, Refining Diagnosis, and Securing Lo
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.04.9

Abstract

BACKGROUND: Although heart failure therapy has advanced, many patients still experience functional limitations, which impact their quality of life. OBJECTIVES: To explore the factors influencing heart failure patients' preferences for quality of life and longevity. METHODS: This cross-sectional study was conducted at Adam Malik Hospital, Medan, Indonesia. The study was conducted from April 2023 to October 2023. A total of 143 chronic heart failure patients were included using purposive sampling. Data were collected through interviews and the EuroQol five-dimension five-level questionnaire, EuroQol visual analogue scale, and the Time Trade-Off method. Statistical analysis was performed using multivariate logistic regression. RESULTS: Of the 143 patients, 66.4% preferred quality of life over longevity, and 47.3% were willing to trade two years of their lives for a better quality of life. The main factors associated with this preference were heart failure with reduced ejection fraction (OR: 3.554; 95% CI: 1.373 - 9.198; p: 0.009), diabetes mellitus (OR: 2.705; 95% CI: 1.108 - 6.602; p: 0.029), and lower visual analog scale scores (OR: 0.889; 95% CI: 0.848 - 0.932; p: 0.000). Our results also showed that patients in the longevity group had better ejection fractions, fewer rehospitalizations, and were less likely to have diabetes mellitus or chronic kidney failure compared to the quality of life group. CONCLUSION: The majority of heart failure patients choose quality of life over longevity, and this may be influenced by symptom burden and rehospitalization history. These findings emphasize the importance of patient-centered therapy focusing on symptom management and psychosocial support.
Community Empowerment in Household Clean and Healthy Behavior (PHBS), especially for Prevention and Early Action on Infectious Diseases and Cerebrocardiovascular Diseases in Pekan Village, Tanjung Beringin District, Serdang Bedagai Arina, Cut Aria; Rusdiana, Rusdiana; Andra, Cut Aryfa; Andriyani, Yunilda; Ginting, Yehezkiel
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 2 (2023): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/abdimastalenta.v8i2.9589

Abstract

Infectious diseases, especially those transmitted by mosquitoes, are health problems that are often experienced by people in coastal areas. Cases of infection such as dengue hemorrhagic fever (DHF) and even malaria, were reported to be found in partner areas. The partner's location which is located on the beach with swamps around it allows breeding places for mosquitoes, especially Anopheles sp. which acts as the main vector of malaria and filarial. Breeding sites for Aedes aegypti and Aedes albopictus mosquitoes as dengue vectors are also possible to be found in partner locations because they are located not too far from the city of Medan and include tourist attractions. Cerebrocardiovascular disease, especially stroke and coronary heart, has high morbidity and mortality rates. This disease has almost the same risk factors because both are related to blood vessels, five main risk factors can be controlled, namely hypertension, diabetes mellitus, dyslipidemia, obesity, and smoking. The importance of public understanding of how to prevent and control these risk factors. Public Health Clinic Center as a front-line health service facility plays an important role in improving the health status of the community. One of the community service activities carried out by the Tanjung Beringin Health Center is counseling to cadres from community members this is related to stroke and coronary heart disease because these diseases are diseases that have a very close relationship and become a problem that requires proper and careful management. The risk factors for these two diseases, including hypertension, cause heart attacks, heart failure, and strokes and often lead to new DM in many cases. Due to the increase in the disease due to lifestyle changes, with this education, we can add to the public's knowledge to be responsive in conducting treatment and regular health checks.
The Overview of Coronary Heart Disease Risk Factors in Perimenopausal and Postmenopausal Female Patients at Haji Adam Malik General Hospital in 2021 Faustine, Elaine; Andra, Cut Aryfa; Dalimunthe, Dina Arwina; Haykal, Teuku Bob; Andriyani, Yunilda
SCRIPTA SCORE Scientific Medical Journal Vol. 5 No. 1 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v5i1.12615

Abstract

ABSTRACT Background: Cardiovascular diseases are taking an estimated 17, 9 million lives each year, 85% were caused by coronary heart disease. After menopause, there are physiological changes that occurs in women’s body that increase the risk of coronary heart disease. Risk factors associated with the incidence of coronary heart disease are, family history, age, hypertension, diabetes, dyslipidemia, obesity, and smoking. Objectives: To examine the risk factors associated with the incidence of coronary heart disease in perimenopausal and postmenopausal women at RSUP Haji Adam Malik in 2021. Methods: This study is a descriptive study with cross sectional design and retrospective approach, carried out at RSUP Haji Adam Malik. The data were taken from 1 January-31 December 2021. Results: The results showed that out of 75 perimenopausal and postmenopausal women who suffered from CHD, 61 patients (81,3%) were >50 years old, 3 patients (4%) had a family history of CHD, 53 patients (70,7%) had hypertension, 45 patients (60%) had diabetes, 58 patients (77,3%) with dyslipidemia, 10 patients (13,3%) were obese, and 14 patients (18,7%) had a history of smoking. Conclusion: Risk factors for CHD in perimenopausal and postmenopausal women, are having a family history of CHD, age, hypertension, diabetes, dyslipidemia, obesity, and smoking. Keywords: coronary heart disease, risk factors, perimenopausal women, postmenopausal women, women with CHD   ABSTRAK Latar Belakang: Penyakit kardiovaskular menyebabkan kematian 17,9 juta penduduk dunia setiap tahunnya, dan 85% diantaranya disebabkan oleh penyakit jantung koroner. Pada wanita yang telah mengalami menopause, terjadi perubahan fisiologis pada tubuh wanita sehingga risiko penyakit jantung koroner meningkat. Faktor risiko yang meningkatkan kejadian penyakit jantung koroner antara lain, usia, riwayat keluarga, hipertensi, diabetes, dislipidemia, obesitas, dan merokok. Tujuan: Untuk mengetahui faktor risiko yang menyebabkan terjadinya penyakit jantung koroner pada pasien wanita perimenopause dan postmenopause di RSUP Haji Adam Malik Medan pada tahun 2021. Metode: Jenis penelitian yang dilakukan adalah penelitian deskriptif dengan desain penelitian cross sectional dengan pendekatan retrospektif, yang dilakukan di RSUP H. Adam Malik. Hasil: Hasil penelitian menunjukkan, dari 75 orang wanita perimenopause dan postmenopause yang menderita PJK, sebanyak 61 pasien (81,3%) berusia >50 tahun, 3 pasien (4%) memiliki riwayat keluarga dengan PJK, 53 pasien (70,7%) menderita hipertensi, 45 pasien (60%) menderita diabetes, 58 pasien (77,3%) mengalami dislipidemia, 10 pasien (13,3%) mengalami obesitas, dan 14 pasien (18,7%) memiliki riwayat merokok. Kesimpulan: Faktor risiko PJK pada wanita perimenopause dan postmenopause, meliputi riwayat keluarga, usia, hipertensi, diabetes, dislipidemia, obesitas, dan merokok. Kata Kunci: faktor risiko, penyakit jantung koroner, wanita dengan PJK, wanita perimenopause, wanita postmenopause