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Antibacterial Potential of Methanol Extract of Red Guava Leaves (Psidium guajava L.) Against Salmonella typhi Gabriella Marchelita Ginting; Ira Gracela; Meldawati; Adek Amansyah
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 15 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i15.685

Abstract

Background: Typhoid fever is a fever caused by an infection of the gastrointestinal tract, where the infection is caused by the bacterium Salmonella typhi. This infection is generally found in environmental conditions with dense populations and poor hygiene levels. Various plants have been used from generation to generation to treat typhoid fever, one of which is red guava leaves. This study aims to further explore the potential of methanol extract of red guava leaves (Psidium guajava L.) on the activity of Salmonella thyphi in vitro. Methods: This study is an in vitro experimental study using Salmonella thyphi culture. The phytochemical screening test was carried out on the methanol extract of red guava leaves. Furthermore, an assessment of the diameter of the inhibition zone between groups was carried out. Univariate and bivariate analyzes were performed to compare between groups. Results: There was an increase in the diameter of the inhibition zone along with an increase in the dose of methanol extract from red guava leaves. A dose of 100 mg/mL of red guava leaf extract showed a maximum inhibition diameter of 11.85 cm. Conclusion: Methanol extract of red guava leaves (Psidium guajava L.) has the antibacterial activity of Salmonella thyphi along with increasing concentrations.
GAMBARAN DIAGNOSTIK DAN PENATALAKSANAAN EKLAMPSIA PADA IBU HAMIL DI RS SARI MUTIARA MEDAN TAHUN 2012-2016 Nico Pemberingan Lumbantoruan; Yulitas Bachtiar; Adek Amansyah
PRIMER (Prima Medical Journal) Vol. 4 No. 1 (2019): Edisi April
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/pmj.v4i1.3062

Abstract

Latar belakang: Penyakit hipertensi dalam kehamilan merupakan kelainan vaskuler yang terjadi sebelum kehamilan atau timbul dalam kehamilan atau pada permulaan nifas. Angka kematian ibu yang berhubungan dengan kehamilan dan persalinan masih sangat tinggi. Menurut Word Healt Organization (WHO),sekitar 500.000 wanita hamil didunia menjadikorban proses reproduksi setiap tahun. Tujuan: Tujuan dari penelitian ini adalah untuk megetahui gambaran Diagnostik dan Penatalaksanaan Eklampsia di RS Sari Mutiara Medan pada tahun 2012-2016. Metode: Jenis penelitian ini adalah deskriptif, metode ini akan mendeskripsikan Gambaran Diagnostik Dan Penatalaksanaan Eklampsia Pada Ibu Hamil Di RS Sari Mutiara Medan. Penelitian ini dilaksanakan pada bulan Januari sampai Desember 2016. Sampel yang digunakan dalam penelitian ini adalah sebagian dari populasi yakni minimal 100 data rekam medis dengan kasus yang mengalami eklampsia di RS Sari Mutiara Medan pada tahun 2012-2016. Hasil: Ditemukan Proporsi paling banyak penderita eklampsia pada ibu hamil di Rumah Sakit Sari Mutiara Medan pada tahun 2012-2016 berdasarkan usia ibu adalah kelompok umur > 35 tahun yaitu 40 % (40 orang), masa gestasi > 34 minggu yaitu 64 % (64 orang), tekanan darah > 160/110 mmHg yaitu 60 % (60 orang), penatalaksanaan farmakologi MgSO4 yaitu 72 % (72 orang), penatalaksanaan tindakan obstetric Sectio caesar yaitu 61 % (61 orang), lama rawatan >5 hari yaitu 59 % (59 orang), dan keadaan sewaktu pulang adalah pulang berobat jalan yaitu 75 % (75 orang).
Antibacterial Potential of Methanol Extract of Red Guava Leaves (Psidium guajava L.) Against Salmonella typhi Gabriella Marchelita Ginting; Ira Gracela; Meldawati; Adek Amansyah
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 15 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i15.685

Abstract

Background: Typhoid fever is a fever caused by an infection of the gastrointestinal tract, where the infection is caused by the bacterium Salmonella typhi. This infection is generally found in environmental conditions with dense populations and poor hygiene levels. Various plants have been used from generation to generation to treat typhoid fever, one of which is red guava leaves. This study aims to further explore the potential of methanol extract of red guava leaves (Psidium guajava L.) on the activity of Salmonella thyphi in vitro. Methods: This study is an in vitro experimental study using Salmonella thyphi culture. The phytochemical screening test was carried out on the methanol extract of red guava leaves. Furthermore, an assessment of the diameter of the inhibition zone between groups was carried out. Univariate and bivariate analyzes were performed to compare between groups. Results: There was an increase in the diameter of the inhibition zone along with an increase in the dose of methanol extract from red guava leaves. A dose of 100 mg/mL of red guava leaf extract showed a maximum inhibition diameter of 11.85 cm. Conclusion: Methanol extract of red guava leaves (Psidium guajava L.) has the antibacterial activity of Salmonella thyphi along with increasing concentrations.
Hubungan Kadar Gula Darah dan Indeks Massa Tubuh terhadap Kejadian Preeklamsia-Eklamsia Daniel Muliadi Vito; Adek Amansyah; Meldawati Meldawati
Jurnal Pendidikan dan Konseling (JPDK) Vol. 4 No. 5 (2022): Jurnal Pendidikan dan Konseling
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jpdk.v4i5.7745

Abstract

Preeklamsia merupakan salah satu kondisi hipertensi pada kehamilan yang dapat menyebabkan masalah pertumbuhan janin dan bahkan kematian pada janin dan ibu. Salah satu faktor pemicu dari kondisi ini adalah peningkatan kadar gula darah (KGD) dan indeks massa tubuh (IMT) > 30 1–3. Penelitian ini bertujuan untuk menemukan hubungan antara variabel kadar gula darah sewaktu dan indeks massa tubuh pada kejadian preeklamsia-eklamsia pada ibu hamil. Desain cross-sectional digunakan dalam penelitian ini. Pengumpulan data dilakukan pada RS Royal Prima Medan dan RS K.H. Daud Arif Kuala Tungkal dalam jangka waktu Juni – Agustus 2022 dengan jenis data sekunder berupa rekam medis. Sebanyak 54 data sekunder yang memenuhi kriteria inklusi berupa ibu hamil > 20 minggu disertai dengan data antropometri, kadar gula darah sewaktu, tekanan darah serta status proteinuria dan riwayat obstetrik, diambil dan digunakan pada penelitian ini. Sampel penelitian cenderung memiliki IMT < 30 dengan jumlah 45 orang (83,3%) dan 9 orang (16,7%) diantaranya memiliki IMT > 30 atau obesitas. Sedangkan KGD pada sampel terbagi rata pada kedua kelompok, 27 orang (50%) pada masing masing kelompok KGD ? Median (88,5 mg/dL) dan > Median (88,5 mg/dL). Tidak tampak hubungan signifikan antara IMT dan kejadian preeklamsia-eklamsia dengan nilai P = 0,142, namun terdapat beda rerata yang signifikan (nilai P < 0,05) antara kelompok kontrol (median IMT 23,44) dan kasus (median IMT 26,56). Hubungan yang signifikan antara kadar gula darah sewaktu dan kejadian preeklamsia-eklamsia dapat disimpulkan (P < 0,05), serta beda rerata yang signifikan antara kelompok kontrol (median KGD 82 mg/dL) dan kelompok kasus (median KGD 95 mg/dL).
Hubungan Antara Nilai Neutrophil Lymphocyte Ratio (NLR) dan Indeks Massa Tubuh (IMT) terhadap Kejadian Preeklampsia pada Wanita Hamil Andreas Natanael Siagian; Adek Amansyah; Meldawati Meldawati
Jurnal Pendidikan dan Konseling (JPDK) Vol. 4 No. 6 (2022): Jurnal Pendidikan dan Konseling
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jpdk.v4i6.8417

Abstract

Preeklampsia adalah kumpulan gejala yang ditandai dengan hipertensi dan protein dalam urin, umumnya terjadi pada kehamilan diatas 20 minggu. Nilai neutrophil lymphocyte ratio (NLR) yang meningkat menunjukkan adanya inflamasi sistemik dan disfungsi endotel yang terjadi pada penderita preeklampsia. Tujuan penelitian ini untuk menilai hubungan antara nilai neutrophil lymphocyte ratio (NLR) dan indeks massa tubuh (IMT) terhadap kejadian preeklampsia pada wanita hamil. Penelitian ini menggunakan pendekatan cross sectional. Pengambilan data sampel dilaksanakan di RSU. Royal Prima Medan dan RSU. Royal Prima Jambi dalam jangka waktu Januari - Agustus 2022 dengan jenis data sekunder berupa rekam medis. Jumlah sampel penelitian ini 50 orang. Berdasarkan IMT sampel penelitian cenderung memiliki BMI < 30 dengan jumlah 41 orang (82,0%) dan 9 orang (18.0%) memiliki BMI > 30 atau obesitas. Berdasarkan NLR sampel terbagi pada dua kelompok, kelompok NLR ? Median (3,46) 24 orang (48,0%), pada kelompok NLR > Median (3,46) 26 orang (52,0%). Dapat dilihat tidak adanya hubungan yang signifikan antara IMT dan preeklampsia dengan nilai P = 0,066, namun terdapat beda rerata yang signifikan (P <0,05) dengan kelompok kontrol (median 23,43) dan kasus (median 26,67). Terdapat hubungan yang signifikan antara NLR dengan kejadian preeklampsia (P < 0,05), serta beda rerata yang signifikan dengan kelompok kontrol (median 2,99) dan kasus (media 4,27).
The Effect of Lean Approach on Hospital Service Quality and Inpatient Satisfaction Anton Timur Jailani Harahap; Chrismis Novalinda Ginting; Ali Napiah Nasution; Adek Amansyah
Unnes Journal of Public Health Vol 12 No 1 (2023): Unnes Journal of Public Health
Publisher : Universitas Negeri Semarang (UNNES) in cooperation with Association of Indonesian Public Health Experts (Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/ujph.v12i1.57692

Abstract

Measurement of the service quality is very important, especially to improve service quality and get loyal customers in a private hospital using a lean service approach. This research aims to determine the effect of a lean service approach based on variables including overproduction, waiting time, transportation, excess processing, inventory, motion and satisfaction defects. This study used a quantitative method approach with a cross-sectional design. The population were treated in the inpatient ward of Malahayati Hospital, Medan. The sample size was 110 patients, determined by Rao formula. The sampling technique was a purposive sampling technique with inclusion criteria of patients who were hospitalized for more than three days on March 2021. Data obtained were analyzed with the logistic regression tests. The results showed all variable have significant effect on the inpatient satisfaction including over production (p = 0.019), followed by waiting time (p = 0.012), transportation (p = 0.011), excess processing (p = 0.017), inventory (p = 0.010), motion (p = 0.015), and satisfaction defects (p = 0.010). Based on multivariate analysis concluded that hospital service quality affects inpatient satisfaction based on the waste inventory (4.567 times) as the highest and waste transportation (2.786 times) as the lowest. This study has strongly suggested that the hospital management should maintain over production waste and other waste variables in order to improve the service quality.
The Relationship of Various Physical Activities To Menopausal Symptoms Naurah Al’Ariqoh; Adek Amansyah; Meldawati Meldawati
Asian Journal of Social and Humanities Vol. 2 No. 03 (2023): Asian Journal of Social and Humanities
Publisher : Pelopor Publikasi Akademika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59888/ajosh.v2i03.195

Abstract

The purpose of this study was to identify the relationship of various physical activities to menopausal symptoms in women aged 50-60 years in the work area of the Ujunggading Health Center. Research Method: This study uses a correlation research design with a cross sectional approach model with a sample of 75 respondents with a non-probability sampling method, namely using purposive sampling, data collection using GPAQ and MRS questionnaires, data analysis using correlation tests. Results: The results of the study of 75 respondents found the frequency distribution of respondents' characteristics with the most jobs as housewives, namely 23 people (30.7%), the most junior high school education was 20 people (26.7%), and the most menopause duration of 5-7 years, which was 36 people (48.0%). Showing that most respondents had moderate category physical activity 54 (72%) and most respondents experienced moderate category menopausal symptoms 37 (49.3%) There was a relationship between physical activity and menopausal symptoms with p value = 0.000 (p < 0.05). Conclusion: There is a relationship between physical activity and menopausal symptoms where the higher the physical activity carried out, the less menopausal symptoms are felt, menopausal symptoms can be reduced by routinely doing activities and exercising for 15 to 60 minutes every day
Detection of glibenclamide adulteration in herbal remedies for diabetes mellitus using TLC Budi, Andre; Razoki, Razoki; Harahap, Halimah; Amansyah, Adek; Edlin, Edlin; Tarigan, Susiani
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 1 (2024): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i1.5287

Abstract

The widespread use of jamu, a traditional Indonesian herbal medicine, has been accompanied by a surge in adulteration with synthetic drugs to enhance efficacy and sales. This study aimed to detect the presence of glibenclamide, a common adulterant, in antidiabetic jamu product using TLC. This study employed three herbal medicine samples marketed for lowering blood glucose levels, with glibenclamide BPFI serving as a reference standard. Thin-layer chromatography, employing a mobile phase consisting of chloroform, cyclohexane, ethanol, and glacial acetic acid (9:9:1:1), was utilized for the analysis. Thin-layer chromatography (TLC) analysis revealed a standard Rf value of 0.4 for glibenclamide, producing a distinct blue-violet spot when visualized with 10% sulfuric acid. The results indicated that the tested herbal medicine samples did not contain the pharmaceutical substance glibenclamide. This conclusion was drawn from the absence of a corresponding Rf value for glibenclamide in the herbal samples when compared to the reference standard.
Hubungan jumlah paritas terhadap usia menopause Grasiah, Joster; Amansyah, Adek; Pratama, Irza Haicha; Djohan, Djohan
Jurnal Prima Medika Sains Vol. 4 No. 1 (2022): Juni
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v4i1.2260

Abstract

Semakin meningkatnya jumlah wanita berusia 59 tahun di Indonesia, menjadi penting untuk mecegah menopause pada usia yang terlalu dini. Jumlah paritas merupakan salah satu faktor yang penting untuk mencegah menopause lebih cepat. Oleh karena itu penelitian ini bertujuan untuk mengetahui hubungan antara paritas terhadap menopause pada pasien di Rumah Sakit Umum Royal Prima. Penelitian ini merupakan penelitian cross-sectional pada 30 pasien menopause di Rumah Sakit Umum Royal Prima yang dipilih dengan simple random sampling. Analisa data yang dilakukan untuk menilai pengaruh jumlah paritas terhadap usia menopause adalah uji Kruskal-Wallis dan korelasi spearman rho. Hasil penelitian menunjukkan bahwa rata-rata pasien menopause berada pada usia 67.10 tahun dengan kecenderungan mengalamai menopause pada usia 54 tahun. Terdapat perbedaan yang signifikan terhadap usia menopause pada masing-masing kelompok paritas (p= 0,023). Selain itu, hasil analisa statistik lainnya juga menunjukkan bahwa terdapat korelasi yang bersifat positif antara jumlah paritas terhadap usia menopause (p= 0.05; koefisien korelasi: 0.874). Oleh karena itu, jumlah paritas secara signifikan mempengaruhi usia menopause, dimana pasien dengan jumlah paritas yang banyak cenderung mengalami menopause yang lebih lama.
The Role of Physical Activity in Menopausal Women Amansyah, Adek; Naurah Al’Ariqoh; Meldawati
Community Medicine and Education Journal Vol. 5 No. 1 (2024): Community Medicine and Education Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/cmej.v5i1.441

Abstract

Menopause is the permanent cessation of the menstrual cycle due to decreased ovarian function, resulting in a decrease in follicles. A person is said to be experiencing menopause if they do not experience menstruation for 12 months. Symptoms that occur during menopause include somatic, psychological, and urogenital symptoms. Exercise has many benefits for body health. Exercise, such as regular physical activity, is considered to reduce complaints during menopause. This study aims to identify the relationship between various physical activities and menopausal symptoms in women aged 50-60 years in the working area of the Ujunggading Health Center. This research uses a correlation research design with a cross-sectional approach model with a sample size of 75 respondents using the nonprobability sampling method, namely using purposive sampling, data collection using GPAQ and MRS questionnaires, and data analysis using correlation tests. The results of the research from 75 respondents showed that the frequency distribution of the characteristics of respondents with the highest occupation was as a housewife, namely 23 people (30.7%), the highest education was junior high school, namely 20 people (26.7%), and the highest duration of menopause was 5-7 years, namely 36 people (48.0%). Shows that many respondents have physical activity in the moderate category 54 (72%), and many respondents experience menopausal symptoms in the moderate category 37 (49.3%). There is a relationship between physical activity and menopausal symptoms with a p-value = 0.000 (p<0.05). There is a relationship between physical activity and menopausal symptoms where the higher the physical activity carried out, the less menopausal symptoms are felt, menopausal symptoms can be reduced by routinely doing activities and exercising for 15 to 60 minutes every day.