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ABVD versus Stanford V Regimen in Unfavorable Classical Hodgkin’s Lymphoma SUPIT, TOMMY; AMIN, ZULKIFLI
Indonesian Journal of Cancer Vol 7, No 4 (2013): Oct - Dec 2013
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

Latar belakang: dilaporkan pasien yang terdiagnosis unfavorable limfoma Hodgkin klasik stadium IIB. Pedoman terapi onkologi memasukkan regimen doxorubicin, bleomycin, vinblastine and dacarbazine (ABVD) dan Standford V sebagai pilihan pengobatan. Namun, sampai saat ini tidak ada tinjauan sistematis atau analisis-meta yang membandingakan kedua rejimen tersebut yang spesifik untuk kasus ini. Studi kasus ini akan menganalisis hasil uji klinis untuk mengetahui apakah salah satu dari rejimen yang tersebut lebih unggul berdasarkan efikasi klinis dan profil toksisitas.Metodologi: pencarian sistematis dilakukan melalui database EMBASE and Cochrane.Laporan kasus ini menelaah beberapa publikasi dalam bahasa Inggris yang berdasarkan uji klinik acak terkendali.Hasil: tiga hasil uji klinik acak terkendali dengan ketersediaan teks lengkap dievaluasi dalam laporan ini. Dua penelitian telah menunjukkan keunggulan ABVD dibandingkan dengan rejimen Standford V yang dimodifikasi, sementara studi lain menunjukkan keunggulan ABVD yang tidak signifikan. Namun, komponen radioterapi regimen Standford V yang digunakan dalam ketiga penelitian tersebut lebih restriktif dibanding dengan rejimen Standford V yang standar.Kesimpulan: ABVD dan rejimen Standford V merupakan dua pilihan yang dapat digunakan untuk mengobati limfoma Hodgkin klasik.Kata Kunci: limfoma Hodgkin, ABVD, Stanford V, perbandingan, efikasi klinik, toksisitas, NCCN, ESMO
Demographic, Clinic, Radiologic, and Histopathologic Pattern of Patient with Mediastinal Mass who Died during Treatment at Cipto Mangunkusumo Hospital Jakarta Amin, Zulkifli
Indonesian Journal of Cancer Vol 7, No 1 (2013): Jan - Mar 2013
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

Banyak penyakit dapat timbul atau melibatkan mediastinum. Penyakit-penyakit tersebut adalah tumor primer, metastase, kista, dan infeksi akut atau kronis. Mendiagnosis massa mediastinum seringkali menjadi tantangan mengingat diperlukan standar diagnosis dan rencana perawatan. Meningkatkan risiko pasien dan memutuskan kapan harus melakukan perawatan agresif akan memberikan hasil akhir yang lebih baik dalam menurunkan angka kesakitan dan kematian. Saat ini, pola demografi, klinik, radiologi, dan histopatologi pasien dengan massa mediastinum yang meninggal selama perawatan di RS Cipto Mangunkusumo belum dilaporkan.Tujuan: mendapatkan pola demografi, klinik, radiologi, dan histopatologi pasien dengan massa mediastinum yang meninggal selama perawatan di RS Cipto Mangunkusumo dalam kurun waktu sepuluh tahun terakhir.Metode: penelitian ini merupakan studi cross-sectional deskriptif. Penelitian dilakukan antara April 2010 sampai Juli 2010 dengan mengumpulkan dan mempelajari catatan medis pasien dengan massa mediastinum yang didiagnosis selama Januari 2000 sampai Desember 2009 di RS Cipto Mangunkusumo, kemudian diproses dengan program SPSS versi 16.0.Hasil: terdapat 201 pasien yang didiagnosis memiliki massa mediastinum di RS Cipto Mangunkusumo selama sepuluh tahun terakhir. Delapan puluh delapan catatan medis tidak ditemukan sehingga hanya ada 113 sampel yang diteliti. Empat puluh lima sampel (39,8%) dari 113 sampel meninggal selama perawatan di rumah sakit.Kesimpulan: ada sedikit perbedaan dalam pola demografi, klinik, radiologi, dan histopatologi pasien dengan massa mediastinum yang meninggal selama pengobatan di RS Cipto Mangunkusumo dibandingkan dengan penelitian lain. Tingkat kematian selama pengobatan tinggi. Diagnosis yang tepat pada stadium dini sangat diperlukan untuk menurunkan angka kesakitan serta angka kematian dan pasien memperoleh hasil akhir yang lebih baik.Kata kunci: massa mediastinum, kematian, sindrom vena cava superior
Characteristics of Mediastinal Tumor Patients in Cipto Mangunkusumo National Hospital Jakarta Amin, Zulkifli
Indonesian Journal of Cancer Vol 7, No 2 (2013): Apr - Jun 2013
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

Tumor mediastinum mewakili keragaman penyakit di berbagai negara. Di Indonesia, khususnya di Rumah Sakit Nasional Cipto Mangunkusumo, masih kekurangan karakteristik epidemiologi, klinis, radiologi, dan karakteristik histopatologi dari tumor mediastinal.Tujuan: untuk menentukan karakteristik kasus-kasus tumor mediastinum berbasis rekam medis. Metode: penelitian retrospektif ini didasarkan pada data yang telah dilaporkan dalam Chest meetings yang diselenggarakan oleh Divisi Pulmonologi Penyakit Dalam Rumah Sakit Cipto Mangunkusumo dari Januari 2007 sampai Desember 2008. Saat penelitian, terdapat 27 kasus tumor mediastinum.Hasil: kebanyakan pasien didiagnosis tumor mediastinum pada usia di atas 40 tahun (56%) dan lebih dari separuh pasien berjenis kelamin laki-laki (67%). Dari 13 pasien (52%) telah dipastikan bahwa 9 dari mereka memiliki riwayat merokok. Tiga gejala yang paling umum ditemukan di antaranya batuk, terengah-engah, dan terjadinya penurunan berat badan. Jenis histologis yang paling umum dari tumor adalah thymoma (33%). Tujuh belas pasien (63%) di antaranya pernah menjalani pembedahan. Radioterapi oleh 44% pasien dan kemoterapi oleh 26% pasien.Kesimpulan: peneliti menangani 27 kasus tumor mediastinum dari Januari 2007 hingga Desember 2008. Lebih dari separuh kasus terjadi pada usia di atas 40 tahun dan thymoma adalah temuan histopatologis yang paling umum.Kata kunci: tumor mediastinum, thymoma.
An Indonesian Pregnant Woman with Lung Cancer and Liver Metastasis : A Case Report Jayalie, Vito Filbert; Priantono, Dimas; Amin, Zulkifli
Indonesian Journal of Cancer Vol 12, No 2 (2018): April-June
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (472.237 KB) | DOI: 10.33371/ijoc.v12i2.580

Abstract

Background: Lung cancer in pregnancy is a rare disease compared to other types of cancer. However, special issue should be applied in order to maximize benefit for mother without harming the fetus.Methods: We present a case of 37-year-old, five months pregnant woman who came to the hospital with chief complain of shortness of breath. Later on, she was found to have a stage IV Non-Small Cell Lung Cancer (NSCLC) with adenocarcinoma subtype.Result: This may be the first lung cancer in pregnancy reported in Indonesia. Being a developing country, several challenges emerged before diagnosing patient of having lung cancer.Conclusion: Careful considerations along with multidisciplinary approach are necessary to provide the best care for the patient.
Pendekatan Diagnosis dan Tatalaksana Sindrom Mirizzi Putra, Ario Perbowo; Christine, Griskalia; Amin, Zulkifli; Fauzi, Achmad
Jurnal Penyakit Dalam Indonesia Vol. 2, No. 3
Publisher : UI Scholars Hub

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Abstract

Penyakit batu empedu telah menjadi masalah kesehatan penting di banyak negara. Estimasi prevalensi penyakit batu saluran empedu yang menyertai penyakit batu empedu adalah sekitar 10-15% dan meningkat dengan usia lanjut. Sindrom Mirizzi adalah komplikasi dari penyakit batu empedu yang jarang terjadi. Karakteristik yang khas yaitu adanya impaksi batu empedu di duktus sistikus atau di leher kandung empedu sehingga menghasilkan obstruksi mekanik di duktus hepatikus dan menghasilkan striktur inflamasi di saluran empedu, sehingga menyebabkan ikterus obstruktif berkelanjutan. Kami laporkan sebuah kasus Sindrom Mirizzi pada laki-laki dewasa yang menyebabkan iketerus obstruktif dengan kolelitiasis.
The Relationship of Reading Interest with Learning Outcomes in Class IX MTS Students' Civics Subjects Single Islamic Academic Year 2017/2018 Pratiwi, Erni; Amin, Zulkifli
EDUCTUM: Journal Research Vol. 1 No. 1 (2022): EDUCTUM: Journal Research
Publisher : Lembaga Riset Mutiara Akbar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (535.201 KB) | DOI: 10.56495/ejr.v1i1.257

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The problem of this research is whether there is a relationship between reading interest and student learning outcomes in citizenship education subjects at MTs. Islamiyah Sunggal in the 2017/2018 academic year. The purpose of this study was to determine the relationship between reading interest and student learning outcomes in citizenship education subjects at MTs. Islamiyah Sunggal in the 2017/2018 academic year. The population used in this study was class IX at MTs. Islamiyah Sunggal Medan which consisted of 4 classes with a total of 129 students. The sampling technique in this study used purposive sampling, namely the class that was the sample studied was class IX with 30 students. The instrument used is a closed questionnaire. In which this questionnaire conducted observations at MTs. Islamiyah Sunggal Medan and a questionnaire on the Relationship of Reading Interest with Student Learning Outcomes. From the results of this study, it can be seen that there is an increase in student learning outcomes with the relationship between reading interest and the research conducted, it is found that the relationship between reading interest is very influential on student learning outcomes in the subject of Citizenship Education. This is evidenced by the value of the correlation coefficient r?count = 1.094. From table r Product Moment for N = 30 obtained rtable = 0.361. So, because (1.094) > (0.361) then the correlation is very strong. From the results of the calculation of the hypothesis obtained t?itung = 13.075 with a significant level = 0.05 and dk = n – 2 = 30 – 2 = 28, then get the price = 1.701. Obtained t?itung13.075> 1.701. This means that Ha is accepted, meaning that there is a significant influence between the relationship between reading interest and student learning outcomes. Thus, it is concluded that there is a relationship between reading interest and student learning outcomes in civic education subjects at MTs. Islamiyah Sunggal Medan in the 2017/2018 academic year
The Role of PPKN Teachers in Strengthening Anti-Corruption Values in Class X at SMA Negeri 1 Sarolangun Febriyanti, Wiwit; Amin, Zulkifli
EDUCTUM: Journal Research Vol. 2 No. 1 (2023): EDUCTUM: Journal Research
Publisher : Lembaga Riset Mutiara Akbar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (249.065 KB) | DOI: 10.56495/ejr.v2i1.276

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Where anti-corruption education is a conscious effort to provide understanding and prevention of acts of corruption committed from formal education in schools, informal education in the family environment, and non-formal education in the community. Most people may still think that corruption is only limited to the act of someone taking money that is not rightfully theirs. In fact, corruption can actually arise from various causes and even the place where corruption occurs is not only limited to the political arena. Education is recognized as the easiest and most effective strategy for changing, at least directing one's way of thinking and mindset in acting. Schools occupy a strategic position in implementing anti-corruption education, especially in cultivating anti-corruption behavior among students. Therefore, the researchers conducted this research with the aim of finding out the role of PKN teachers in strengthening anti-corruption values in class X at SMA Negeri 1 Sarolangun in the 2022/2023 academic year, with a total of 36 students. Using quantitative research methods, data collection techniques in this study were observation and questionnaire distribution in class X. Data analysis techniques used in this study were normality tests and hypothesis testing. The results of the analysis show that regarding variable (x) the role of PKN teachers in strengthening anti-corruption values. It can be seen from the significant value of the role of the pkn teacher (x) 0.000 <0.05 but in the value thitung 2,548 > 1.688 (t tabel = 0.05:1.688) So it can be concluded that there is a positive influence and significant between the independent variable and the dependent variable.
IMPLEMENTASI PEMBELAJARAN PKN DALAM PEMBENTUKAN KARAKTER GENERASI MUDA GOOD AND SMART CITIZENSHIP DI ERA RESOLUSI INDUSTRI 4.0 Taufika, Ryan; Amin, Zulkifli
GOVERNANCE: Jurnal Ilmiah Kajian Politik Lokal dan Pembangunan Vol. 10 No. 1 (2023): 2023 September
Publisher : Lembaga Kajian Ilmu Sosial dan Politik (LKISPOL)

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Abstract

In the current era of the industrial revolution 4.0, learning is needed that can have a significant impact in answering opportunities and challenges in producing the quality and quality of the young generation with character who will become the future of the nation. This study aims to determine the implementation of Civics learning in Higher Education in shaping the moral character of Good and Smart Citizenship students in preparing the future of the nation. This type of research is qualitative, with analytical descriptive methods used to describe, analyze, and describe a condition of the subject or object under study based on facts that occur in the field about how to implement PKn learning. The subjects in this study are Civics lecturers and PKn students. Civics learning is very important in the formation of a nation character that is tough, competitive and able to solve social problems in the life of the nation and state. Civics learning fosters citizens to become good and smart citizens. Civics aims to develop the character and character of citizens in accordance with noble values and Pancasila.
Utilization of the Kahoot-it Application as a Learning Vehicle Based on Massive Open on Line Course (MOOC) during the Covid-19 Pandemic Amin, Zulkifli; Dahnial, Irfan
Budapest International Research and Critics Institute-Journal (BIRCI-Journal) Vol 4, No 4 (2021): Budapest International Research and Critics Institute November
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v4i4.3343

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This research shows that in the preparation stage, the implementation does the following things. (a) The implementer conducts socialization to the students of the Muhammadiyah University of North Sumatra through the Zoom media. (b) Implementers prepare questionnaires, attendance lists and other files for the purposes of activity reports. (c) Implementers re-register students who are actively enrolled in the class. (d) Executors prepare hardware devices in the form of computers/laptops, LCDs and so on. The approach in this research is qualitative (qualitative research). What is meant by qualitative research is to understand the phenomenon of what is experienced by the research subject holistically, and by means of description in the form of words and language, in a special natural context and by utilizing various scientific methods. From several different samples of students, there was a significant difference in the implementation of independent learning using MOOC-based Kahoot-it media. Therefore, these two different classes must be further improved with several methods that will be given later to students or later, so that the implementation of independent learning itself is carried out properly.
The Influence of the Project Based Learning (PjBL) Learning Model in Civics Subjects on the Development of Students' Civic Skills at SMP Muhammadiyah 19 Pematangsiantar TP. 2022/2023 Nisa, Khairun; Amin, Zulkifli
Holistic Science Vol. 3 No. 2 (2023): Jurnal Nasional Holistic Science
Publisher : Lembaga Riset Mutiara Akbar NOMOR AHU-0003295.AH.01.07 TAHUN 2021

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56495/hs.v3i2.387

Abstract

This research aims to find out the influence of the Project Based Learning (PjBL) learning model in Civics subjects on the development of student’s civic skills. This research uses quantitative research. The objects of this research were class VIII students of SMP Muhammadiyah 19 Pematangsiantar and data collection techniques used questionnaires, observation and documentation. The data analysis techniques used are validity tests, reliability tests, normality tests, and using the "t" test. Based on the calculation of the validity test there are 20 questions, after carrying out the validity test it is > 0.388 then it is declared that the whole is valid, the reliability test value (x) obtained is 0.640 and the value (y) obtained is 0.841 so it is declared reliable, the normality test value obtained is 0.197 then it is normally distributed. And after carrying out the "t" Paired Sample Test using SPSS 26.0, namely a sig value of 0.00, then sig < 0.05 (0.00 < 0.05). So, Ha is accepted, Ho is rejected. This proves that Civics learning on the development of student’s civic skills using the Project Based Learning (PjBL) learning model has an influence compared to before using the Project Based Learning (PjBL) learning model