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Journal : JURNAL FARMASIMED (JFM)

PENGARUH LILIN AROMATERAPI MINYAK LAVENDER (LAVANDULA ANGUSTIFOLIA) TERHADAP KONSENTRASI BELAJAR PADA SISWA MADRASAH TSANAWIYAH AL-WASHLIYAH PASAR MIRING DI DESA PASAR MIRING anggraeni, Ratih; ., Muriati; Pranata, Chandra
Jurnal FARMASIMED (JFM) Vol 3 No 2 (2021): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v3i2.678

Abstract

Aromatherapy is an ancient healing process that uses pure aromatherapy plant extracts aimed at improving the health and well-being of the body, mind and spirit. Lavender contains linalil acetate and linalool. Linalil acetate and linalool have no harmful side effects on health. This substance is antibacterial, fungicidal, viriside, parasiticidal and vermifugal and has neurotonic and uterotonic action. This study aims to determine the effect of lavender oil (Lavandula angustifolia) aromatherapy candles on increasing the concentration of student learning at the Madrasah Tsanawiyah Al-Wasliyah Pasar Miring in Desa Pasar Miring . The study used a quasi-pretest-posttest experimental method for 30 randomly selected students. The instrument in this study used the Army Alpha Test with data analysis using Paired T-Test. Hypothesis testing using Paired T-Test showed p value = 0.026<0.05 (p <0.05). It can be concluded that there is an influence of lavender oil aromatherapy candles on increasing the concentration of student learning in Madrasah Tsanawiyah Al-Wasliyah Pasar Miring in Desa Pasar Miring
TEST THE ANTIBACTERIAL ACTIVITY OF ETHANOL EXTRACT OF CRASSOCEPHALUM CREPIDIOIDES LEAF AGAINST STREPTOCOCCUS PYOGENES anggraeni, Ratih; Lingga, Nola Monalisa
Jurnal FARMASIMED (JFM) Vol 4 No 2 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v4i2.1082

Abstract

The ethanol extract of Crassocephalum crepidioides leaves was tested against Streptococcus pyogenes bacteria. Extracts from the leaves of Crassocephalum crepidioides are known to have the potential to suppress microbial growth because contain active compounds of alkaloids and flavonoids. The test was carried out by the diffusion method using disc paper that had been soaked in a solution of ethanol extract of Crassocephalum crepidioides leaves with a concentration of 20%, 30%, 40%, 50%. Amoxicillin as a positive control and DMSO as a negative control. It is known that the inhibition of bacterial growth at a concentration of 20% the inhibition zone is 11mm, the concentration of the inhibition zone of 30% is 11.8mm, the concentration of 40% of the inhibition zone is 12.2mm, the concentration of 50% is the inhibition zone is 12.6mm. The higher the concentration of the ethanol extract of Crassocephalum crepidioides leaves, the wider the area of inhibition against Streptococcus pyogenes bacteria.
EVALUATION OF ANTIBIOTICS USE IN DALU SEPULUH PUSKESMAS TANJUNG MORAWA anggraeni, Ratih; Samgryce Siagian, Hartika; Anggraini Sembiring, Syaiba
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1308

Abstract

Antibiok sering digunakan untuk mengatasi infeksi bakteri. Kurangnya pengetahuan masyarakat tentang penggunaan antibiotik menjadi salah satu faktor resiko terjadinya peningkatan resiko bakteri terhadap antibiotik. Penelitian ini bertujuan untuk mengetahui bagaimana tingkat pemahaman tentang penggunaan antibiotik di puskesmas Dalu sepuluh Tanjung Morawa. Desain penelitian ini adalah penelitian deskriptif dengan tehnik sampel yaitu purposive sampling pada subjek sebanyak 70 orang tanjung morawa.
EVALUATION OF ANTIDIABETIC USAGE IN TYPE II DM PATIENTS AT PUBLIC HEALTH CENTRE OF SEI KEPAYANG BARAT ASAHAN DISTRICT Rahayu, Yayuk Suyudi; Anggraeni, Ratih; Tanjung, Nurhaliza
Jurnal FARMASIMED (JFM) Vol 5 No 1 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i1.1321

Abstract

Diabetes Melitus merupakan suatu kondisi dengan gangguan metabolik karena organ pankreas gagal memproduksi hormon insulin. Kondisi ini digolongkan penyakit kronis karena berlangsung menahun. Diabetes melitus digolongkan menjadi tiga jenis, yaitu DM tipe I, II, dan gestasional. Evaluasi penggunaan antidiabetes bertujuan untuk mendukung program pemerintah secara terstruktur dan berkesinambungan dalam hal mengontrol penggunaan obat diabetes secara kualitatif dan kuantitatif. Evaluasi ini menggunakan metode deskriptif kuantitatif berdasarkan tepat obat, tepat dosis, tepat indikasi, dan tepat pasien dengan hasil bahwa pravelensi pasien DM tipe II sering terjadi pada perempuan berusia 40-55 tahun. Evaluasi penggunaan antidiabetes di Puskesmas Sei Kepayang Barat terlaksana sesuai ketentuan dan mengacu pada Keputusan Mentri Kesehatan Tahun 2016.
ANTIBACTERIAL TESTED STAPHYLOCOCCUS AUREUS FROM ETHANOL EXTRACT OF NONI FRUIT anggraeni, Ratih
Jurnal FARMASIMED (JFM) Vol 6 No 1 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v6i1.1926

Abstract

The various types of plants that Indonesia has should be protected and maintained in diversity. Many types of plants are used as medicinal plants. Some taste sweet, astringent, sour, and even bitter. One of them is the noni plant. The noni plant has fruit that tastes bitter and gives off an unpleasant odor. However, noni fruit contains antibacterial properties. More than one bacteria is found in the human body. One of them is Staphylococcus aureus which can infect if the immune system is low. The main treatment for bacterial infections uses antibiotics. Frequent use of antibiotics can cause resistance. To overcome this resistance, research was carried out on ethanol extract of noni fruit which is expected to inhibit the growth of these bacteria. This research is experimental using Staphylococcus aureus bacteria as a bacterial test using the disc diffusion method. The antibiotic amoxicillin was used as a positive control. The diameter of the inhibition zone will determine the antibacterial activity of the bacterial medium. The ethanol extract of noni fruit that was tested provided evidence that it could prolong the growth of Staphylococcus aureus bacteria. The concentration of the test solution is divided into 3, namely 25%, 50% and 75%. The diameters of the inhibition zones are 15.67 mm, 19.7 mm, and 23.97 mm, respectively. Differences in the concentration of the test solution can affect the diameter of the inhibition zone in the bacterial medium. The test solution with a concentration of 75% had the best antibacterial inhibition power, namely 23.97 mm. Keywords: noni fruit, Staphyococcus aureus, antibacterial
The Influence of Abdominal Circumference and Body Mass Index On Hypertension anggraeni, Ratih; Marbun, Romauli Anna Teresia; Siagian, Hartika Samgryce; Lubis, Amelia Hasana
Jurnal FARMASIMED (JFM) Vol 7 No 1 (2024): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i1.2358

Abstract

The Body Mass Index (BMI) value is used to determine the body composition value, calculated using a formula involving height and weight. Increasing body weight will affect the size of the stomach circumference. One indicator of BMI that can identify the risk of morbidity due to increased body weight is the measurement of the size of the abdominal circumference. If there is an increase in BMI, the risk of developing hypertension and other heart diseases also increases. Hypertension is when a person's blood pressure exceeds normal (120/80mmHg). This research was conducted to analyze the influence of BMI and abdominal circumference on hypertension symptoms using analytical observation. Random sampling was taken from the USU Faculty of Medicine student population with the criteria of having a history of heart disease, a history of metabolic disease, taking heart medication, and being an athlete. Respondents had their height and weight measured, their BMI values were calculated, then their abdominal circumference, and their blood pressure. The results showed that there was an influence between BMI and abdominal circumference on symptoms of hypertension. There was a significant correlation between BMI and systole (p=0.000) and diastole (p=0.014) as well as a moderate correlation coefficient for systole (r=0.466) and diastole (r=0.340). There is a correlation between abdominal circumference and systole (p=0.000) and diastole (p=0.038) and a moderate level correlation coefficient with systole (r=0.480) and diastole (r=0.289). It can be concluded that there was an influence of BMI and LP on hypertension.
Effort to Reduce The Incidence of Anemia in Grade XII Students of SMAN 1 Sei Rampah Using The Action Research Approach M Taufik Alfyan; Felix Kasim; Fadlilah Widyaningsih; anggraeni, Ratih
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2637

Abstract

Anemia is a condition of low hemoglobin levels in the blood. This condition often occurs in adolescent girls due to menstrual cycles and a tendency to diet. Adolescent girls who suffer from anemia are at risk of giving birth to babies with low birth weight and stunting. The incidence of anemia is very high in North Sumatra, one of which is in Sei Rampah District. Because of this condition, researchers feel the need to make efforts to reduce the incidence of anemia by providing iron tablets. The action research method was carried out to determine whether there were changes in hemoglobin levels in the anemia group of grade XII SMAN 1 Sei Rampah students who were given intervention. The students' hemoglobin levels were measured to group which ones had the potential for anemia, then given iron tablets once a week for 4 weeks and then their hemoglobin levels were measured again. Action research plays a role in achieving a decrease in the incidence of anemia. Researchers concluded that there was an increase hemoglobin levels by 96.7% in the group of female students categorized as anemic after the intervention of anemia concept education and the provision of iron tablets with assistance.
Testing the Activity of Chitosan Nanohydrogel from Belut Sawah (Monopterus albus) Extract as a Future Anti-Aging Candidate anggraeni, Ratih; Romauli Anna Teresia Marbun
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/x4nw7q34

Abstract

Background: Premature aging has become a serious concern, especially among women. The aging process can occur at any time and progress rapidly. This condition may be caused by exposure to sunlight, which induces the formation of Reactive Oxygen Species (ROS) in the skin. When the amount of ROS exceeds the antioxidant defense capacity of skin cells, it can lead to dryness, thinning, loss of elasticity, wrinkles, and even skin cancer. The swamp eel (Monopterus albus) is commonly used as food by the community. Previous studies have shown that eel extract has been used to treat incision wounds, gastric ulcers, and anemia. It contains vitamin A, vitamin B, and selenium. This species is abundantly found in rice fields and muddy ponds in the Lubuk Pakam area. The formulation of the extract into nan chitosan derived from shrimp shells has been reported to improve the delivery of antioxidant effects into the skin layers. Objective: This study aimed to analyze the activity of a hydrogel combining swamp eel extract with nanochitosan, evaluate its antioxidant activity, and assess the physical stability of the hydrogel formulation as an anti-aging preparation. Methods: Extraction was carried out using the maceration method. The nanochitosan-based hydrogel formulation was designed to enhance the delivery of the eel’s active compounds. Antioxidant activity was tested using the 2,2-Diphenyl-1-picrylhydrazyl (DPPH) method, and the physical stability of the hydrogel was evaluated. Results: The physical evaluation showed that the nanochitosan hydrogel containing swamp eel extract maintained good stability during storage. Organoleptic tests indicated a consistent yellowish-white color, characteristic aroma, and uniform texture (homogeneity) from day 0 to day 4. The pH value remained stable at 5.2 throughout weeks 0 to 4, within the physiological range of skin pH. Viscosity measurements were 10,350 cps for F1, 11,750 cps for F2, and 23,650 cps for F3. These findings suggest that the formulation possessed good physical stability and an appropriate consistency for topical application. Conclusion: Skin elasticity and biological activity tests showed an increase in skin firmness, likely due to the collagen, flavonoid, and antioxidant content in the swamp eel extract. Irritation and panelist preference tests confirmed its safety and user acceptability. Therefore, this hydrogel shows potential to be developed as a natural, safe, and consumer-friendly anti-aging formulation.