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Journal : Jurnal Kesehatan

UJI FARMAKOLOGI SEDIAAN PLESTER PATCH DARI LIMBAH KULIT PISANG KEPOK (MUSA ACUMINATA) UNTUK PENYEMBUHAN LUKA BAKAR Syamsuri Syakri
Jurnal Kesehatan Vol 12 No 1 (2019): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v12i1.7395

Abstract

Telah dilakukan penelitian mengenai Uji Farmakologi Sediaan Patch Dari Limbah Kulit Pisang Kepok Untuk Penyembuhan Luka Bakar. Tujuan penelitain ini untuk melakukan uji efektivitas dengan menggunakan hewan coba kelinci, serta pembuatan plester patch untuk memberikan suatu kenyamanan dan kemudahan kepada konsumen dalam mengobati luka. Peneltian ini menggunakan metode kuantitatif dengan cara metode eksperimental laboratorium, cara kerjanya berupa pengambilan sampel, ektraksi kulit buah pisang kepok, membuat plester patch dari 3 macam formula kemudian membandingkan dengan kontrol positif dan negatif, evaluasi plester patch¸dan setelah pengujian daya sembuh luka pada hewan kelinci. Dari hasil penelitian didapatkan Formula III yang memiliki efektifitas paling baik dalam menyembuhkan luka yaitu konsentrasi 30% kulit buah pisang kepok. ABSTRACTResearch has been conducted on the Pharmacological Test of Patches Preparation from Kepok Banana Skin Waste to Heal Burns. The use of immature kepok banana peels to help speed up the duration of wound healing has already been done, but in previous studies, kepok banana peel was extracted, but made in gel form, whereas in patch plaster preparations had never been studied before. The purpose of this research is to make patch plaster preparations that have the best effectiveness in healing wounds, as well as making patch plasters to provide comfort and convenience to consumers in treating wounds. This research uses a quantitative method by means of laboratory experimental methods, how it works in the form of sampling, extraction of kepok banana peel, making patch plaster using active ingredients kepok banana peel extract (Musa acuminate), and other additives in the form of glycerin, chitosan, HPMC, Tween 80, then formulated into 3 types of formulas, then compared with positive and negative controls, evaluation of patch patches and after testing the healing power of wounds in rabbit animals. From the results of the study it was found that Formula III had the best effectiveness in healing wounds, namely the concentration of 30% kepok banana peels.
DETEKSI LEMAK BABI PADA BEBERAPA PRODUK LIPSTIK CAIR IMPOR MENGGUNAKAN SPEKTROFOTOMETER FTIR UNTUK ANALISIS KEHALALAN Syamsuri Syakri
Jurnal Kesehatan The 1st Alauddin Pharmaceutical Conference and Expo (ALPHA-C) 2019
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v0i0.12487

Abstract

A study entitled detection of Pig Fat in Several Imported Liquid Lipsticks Using FTIR Spectrophotometry for. The purpose of this study was to identify pork fat in imported liquid lipstick products using the FTIR Spectrophotometer method, and to conduct a qualitative analysis of pork fat in imported liquid lipstick products using the FTIR Spectrophotometer method. The method used in this study is a qualitative analysis method, for the working procedure begins with the sampling process using a sample of 3 imported liquid lipsticks originating from Korea, Thailand, and China, then extracting oil on product samples, and testing using a spectrophotometer FTIR. After the results are obtained, the FTIR Spectrum Data Interpretation is performed. From these results it was found that the FTIR Spectrophotometer Method can be used to identify lard in imported liquid lipstick products. Based on the results of the comparison of the results of the interpretation of the data of Sample 1, Sample 2 and Sample 3 with the spectra data of pork fat from the journal Hermanto, it can be concluded that Sample 1 and Sample 3 have functional groups that are similar to the interpretation of data from the spectrum of lard in several studies on fat pig. However, if seen from the spectrum, there is a difference between Sample 1, Sample 2 and Sample 3 with the spectrum of lard from the journal. Further research needs to be done using other instruments to ensure the presence of lard content in Sample 1, Sample 2 and Sample 3.
KARAKTERISASI MIKROKRISTALIN SELULOSA DARI KULIT JAGUNG PULUT (Zea mays L. Var Ceratina Kulesh) Surya Ningsi; Nining Iklasita; Munifah Wahyuddin; Syamsuri Syakri
Jurnal Kesehatan THE 2nd ALAUDDIN PHARMACEUTICAL CONFERENCE AND EXPO (ALPHA-C) 2020
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v1i1.15294

Abstract

Corn husk is a part of the plant that has a high cellulose fiber content, which is around 44.08%, so it is potentially to be used as a source of raw material of microcrystalline cellulose. The purpose of this research was to synthesize and determine the characteristics of microcrystalline cellulose produced from corn husk. The making of microcrystalline cellulose was carried out in two stages, namely delignification using NaOH solvent with five variations of concentration (7,5%, 10%, 12,5%, 15% and 17,5%) and hydrolyzed using 2,5 N HCl. Characteristic test for microcrystalline cellulose included organoleptic, pH, flow time and stationary angle, FTIR, and XRD. The results showed that microcrystalline cellulose produced from corn husk had characteristics such as fine powder, white and odorless, pH was 7.0, flow time was 0.3 g/sec, a stationary angle was 54o, FTIR analysis showed a typical peak of cellulose namely 3411,05 for O-H and 2900,61 for C-H, with a crystallinity degree was 79%.
POTENSI KEARIFAN LOKAL TANAMAN Ficus SEBAGAI ANTIOKSIDAN Syamsuri Syakri; Mukhriani Mukhriani; Kairun Nisa; St. Aisyah S
Jurnal Kesehatan Vol 14 No 1 (2021): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v14i1.17324

Abstract

The Ficus plant is made up of roughly hundreds of species that are scattered across South, Southeast Asia, and there are 76 types of Ficus plants in Indonesia. Ficus is a plant that is widely used for the prevention of various diseases. Several recent studies have shown that the Ficus plant also has antioxidant activity. This work has described the antioxidant potential of the Ficus plant. Overall, these data suggest that Ficus wood can be suggested as as cosmetic ingredient. The bibliographic survey was conducted from January 2016 to April 2020 by analyzing peer-reviewed journals and articles from the past five years. Peer-reviewed articles were indexed by PubMed, GoogleScholar, DOAJ, and ScienceDirect. Only relevant studies published in English and Indonesian will be considered. There are 31 articles reporting the antioxidant activity of Ficus in vitro on DPPH, FRAP and ABTS methods. Based on a review of these articles, we conclude that ficus has the potential to be developed as an antioxidant cosmetic.
STUDI AKTIVITAS INHIBITOR TIROSINASE DAN KADAR FENOLIK TOTAL EKSTRAK METANOL JAMUR TIRAM PUTIH (Pleurotus ostreatus) Nur Syamsi Dhuha; Nur Suci Suci Wahdaniya; Syamsuri Syakri
Jurnal Kesehatan THE 2nd ALAUDDIN PHARMACEUTICAL CONFERENCE AND EXPO (ALPHA-C) 2020
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v1i1.18166

Abstract

Oyster mushroom (Pleurotus ostreatus) contains vitamin B, vitamin C and carbohydrates such as β-glucans, monoterpenoids, triterpenoids, potential sources of lignin and phenols. The presence of phenolic compounds indicates the ability of oyster mushrooms as potential antioxidants and anti-tyrosinases. Searching for depigmentation agents in cosmetics is necessary to ensure safety and reduce side effects. The aims of this study are to determine the inhibitory activity of tyrosinase and total phenolic levels of Pleurotus ostreatus methanol extract. Tyrosinase inhibitor activity was measured using the Enzyme Linked Immunosorbent Assay (ELISA) method at 490 nm with various concentrations, which were 55 ppm, 65 ppm, 75 ppm, 85 ppm and 95 ppm. Determination of total phenolic levels at a concentration of 100 ppm using a UV-Vis Spectrophotometer at 744.8 nm. Based on the research, the percentage of tyrosinase inhibitor of Pleurotus ostreatus methanol extracts at concentrations of 55 ppm, 65 ppm, 75 ppm, 85 ppm and 95 ppm were 17.6%, 19.5%, 22.2%, 25.9%, and 35.7%, respectively. The result of the IC50 and total phenolic content are 9.06% and 1.13%. These results exhibit that the methanol extract of Pleurotus ostreatus has a very strong tyrosinase inhibitor power.